Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 280, Issue 1 43-1, 2001, Pages

  Li, Hui ^a   Meininger, Cynthia J ^b   Hawker Jr , James R ^b   Haynes, Tony E ^a   Kepka Lenhart, Diane ^c   Mistry, Sanjay K ^c   Morris Jr , Sidney M ^c   Wu, Guoyao ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Arginine; Cell transfection; Endothelial metabolism; Ornithine

Indexed keywords

ARGINASE; COMPLEMENTARY DNA; GLUTAMIC ACID; NITRIC OXIDE; POLYAMINE; PROLINE; PUTRESCINE; SPERMIDINE; SYNTHETASE; UREA;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANGIOGENESIS; ANIMAL CELL; ARTICLE; CARDIOVASCULAR FUNCTION; CATTLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNTHESIS; WOUND HEALING;

EID: 0035016176     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2001.280.1.e75     Document Type: Article

References (38)

1. Biochemical and functional profile of a newly developed potent and isozyme-selective arginase inhibitor
2. G-hydroxy-L-arginine during high-output NO production
3. Arginase-boronic acid complex highlights a physiological role in erectile function
4. Induction of intracellular arginase activity does not diminish the capacity of macrophages to produce nitric oxide in vitro
5. Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cells
6. G-hydroxy-L-arginine in alveolar macrophages: Implications for the utilization of L-arginine for nitric oxide synthesis
7. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: Cultured endothelial cells recycle L-citrulline to L-arginine
8. ω-hydroxy-D,L-indospicine, effects on L-arginine utilization by nitric oxide synthase
9. Comparative properties of arginases
10. Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase
11. Arginase I: A limiting factor for nitric oxide and polyamine synthesis by activated macrophages?
12. Nitric oxide synthase in mammals
13. Rapid determination of nitrite by reversed-phase high-performance liquid chromatography
14. Nitrogen metabolism and ornithine cycle function
15. L-Glutamine inhibits nitric oxide synthesis in bovine venular endothelial cells
16. Proliferation of endothelial cells (EC) from diabetic BB rats is impaired
17. Nitric oxide synthases: Which, where, how, and why?
18. A fluorometric assay for the measurement of nitrite in biological samples
19. Molecular mechamsms and therapeutic strategies related to nitric oxide
20. Arginine synthesis, metabolism, and transport: Regulators of nitric oxide synthesis
21. Human type II arginase: Sequence analysis and tissue-specific expression
22. Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells
23. Elevated type I arginase expression enhances polyamine synthesis without inhibiting NO synthesis in RAW 264.7 cells
24. Vascular endothelial cell proliferation: Regulation of cellular polyamines
25. Venular endothelial cells from bovine heart
26. Structure of the murine arginase II gene
27. Coinduction of nitric oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide
28. ω-hydroxynor-L-arginine on NO synthase activity in murine macrophages
29. Urea synthesis in enterocytes of developing pigs
30. Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs
31. The activation of the arginine-citrulline cycle in macrophages from the spontaneously diabetic BB rat
32. Enhanced intestinal synthesis of polyamines from proline in cortisol-treated piglets
33. Regulation of L-arginine synthesis from L-citrulline by L-glutamine in endothelial cells
34. Impaired arginine metabolism and NO synthesis in coronary endothelial cells of the spontaneously diabetic BB rat
35. Arginine nutrition and cardiovascular function
36. Arginine metabolism: Nitric oxide and beyond
37. Maternal dietary protein deficiency decreases nitric oxide synthase and ornithine decarboxylase activities in placenta and endometrium of pigs during early gestation