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Volumn 7, Issue 3, 2002, Pages 149-164

Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs

Author keywords

ACE inhibitors; AT1 receptor antagonists; Atherosclerosis; Diabetes; Endothelial dysfunction; eNOS uncoupling; Glucocorticoids; Hypertension; Oxidative stress; Statins; Staurosporine

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIOXIDANT; CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STATIN; SUPEROXIDE; TACROLIMUS;

EID: 0036430356     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1089-8603(02)00111-8     Document Type: Review
Times cited : (192)

References (201)
  • 1
    • 0036751127 scopus 로고    scopus 로고
    • Physiological mechanisms regulating the expression of endothelial-type NO synthase
    • H. Li, T. Wallerath, U. Förstermann, Physiological mechanisms regulating the expression of endothelial-type NO synthase, Nitric Oxide Biol. Chem. 7 (2002) 103-118.
    • (2002) Nitric Oxide Biol. Chem. , vol.7 , pp. 103-118
    • Li, H.1    Wallerath, T.2    Förstermann, U.3
  • 2
    • 0029021173 scopus 로고
    • Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cells
    • K. Hirata, N. Miki, Y. Kuroda, T. Sakoda, S. Kawashima, M. Yokoyama, Low concentration of oxidized low-density lipoprotein and lysophosphatidylcholine upregulate constitutive nitric oxide synthase mRNA expression in bovine aortic endothelial cells, Circ. Res. 76 (1995) 958-962.
    • (1995) Circ. Res. , vol.76 , pp. 958-962
    • Hirata, K.1    Miki, N.2    Kuroda, Y.3    Sakoda, T.4    Kawashima, S.5    Yokoyama, M.6
  • 3
    • 0028821643 scopus 로고
    • Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase
    • J.K. Liao, W.S. Shin, W.Y. Lee, S.L. Clark, Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase, J. Biol. Chem. 270 (1995) 319-324.
    • (1995) J. Biol. Chem. , vol.270 , pp. 319-324
    • Liao, J.K.1    Shin, W.S.2    Lee, W.Y.3    Clark, S.L.4
  • 4
    • 0032521624 scopus 로고    scopus 로고
    • Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells
    • F. Vidal, C. Colome, J. Martinez Gonzalez, L. Badimon, Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells, Eur. J. Biochem. 252 (1998) 378-384.
    • (1998) Eur. J. Biochem. , vol.252 , pp. 378-384
    • Vidal, F.1    Colome, C.2    Martinez Gonzalez, J.3    Badimon, L.4
  • 5
    • 0042196814 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: Balance between transcriptional and posttranscriptional regulation
    • J. Martinez-Gonzalez, B. Raposo, C. Rodriguez, L. Badimon, 3-Hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: Balance between transcriptional and posttranscriptional regulation, Arterioscler. Thromb. Vasc. Biol. 21 (2001) 804-809.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 804-809
    • Martinez-Gonzalez, J.1    Raposo, B.2    Rodriguez, C.3    Badimon, L.4
  • 6
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • O. Hernandez-Perera, D. Perez-Sala, J. Navarro-Antolin, R. Sanchez-Pascuala, G. Hernandez, C. Diaz, S. Lamas, Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells, J. Clin. Invest. 101 (1998) 2711-2719.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2711-2719
    • Hernandez-Perera, O.1    Perez-Sala, D.2    Navarro-Antolin, J.3    Sanchez-Pascuala, R.4    Hernandez, G.5    Diaz, C.6    Lamas, S.7
  • 7
    • 0029942086 scopus 로고    scopus 로고
    • Endothelial constitutive nitric oxide synthase protein and mRNA increased in rabbit atherosclerotic aorta despite impaired endothelium-dependent vascular relaxation
    • K. Kanazawa, S. Kawashima, S. Mikami, Y. Miwa, K. Hirata, M. Suematsu, Y. Hayashi, H. Itoh, M. Yokoyama, Endothelial constitutive nitric oxide synthase protein and mRNA increased in rabbit atherosclerotic aorta despite impaired endothelium-dependent vascular relaxation, Am. J. Pathol. 148 (1996) 1949-1956.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1949-1956
    • Kanazawa, K.1    Kawashima, S.2    Mikami, S.3    Miwa, Y.4    Hirata, K.5    Suematsu, M.6    Hayashi, Y.7    Itoh, H.8    Yokoyama, M.9
  • 8
    • 0033532524 scopus 로고    scopus 로고
    • A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: Possible relevance of upregulation of endothelial NO synthase mRNA
    • H. Kano, T. Hayashi, D. Sumi, T. Esaki, Y. Asai, N.K. Thakur, M. Jayachandran, A. Iguchi, A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: Possible relevance of upregulation of endothelial NO synthase mRNA, Biochem. Biophys. Res. Commun. 259 (1999) 414-419.
    • (1999) Biochem. Biophys. Res. Commun. , vol.259 , pp. 414-419
    • Kano, H.1    Hayashi, T.2    Sumi, D.3    Esaki, T.4    Asai, Y.5    Thakur, N.K.6    Jayachandran, M.7    Iguchi, A.8
  • 9
    • 0033538644 scopus 로고    scopus 로고
    • Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae
    • T.E. Peterson, V. Poppa, H. Ueba, A. Wu, C. Yan, B.C. Berk, Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae, Circ. Res. 85 (1999) 29-37.
    • (1999) Circ. Res. , vol.85 , pp. 29-37
    • Peterson, T.E.1    Poppa, V.2    Ueba, H.3    Wu, A.4    Yan, C.5    Berk, B.C.6
  • 10
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • H. Cai, D.G. Harrison, Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress, Circ. Res. 87 (2000) 840-844.
    • (2000) Circ. Res. , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 11
    • 0032741623 scopus 로고    scopus 로고
    • Cholesterol-dependent regulation of nitric oxide production: Potential role in atherosclerosis
    • R.J. Coppinger, C.L. Baum, Cholesterol-dependent regulation of nitric oxide production: Potential role in atherosclerosis, Nutr. Rev. 57 (1999) 279-282.
    • (1999) Nutr. Rev. , vol.57 , pp. 279-282
    • Coppinger, R.J.1    Baum, C.L.2
  • 13
    • 0032580971 scopus 로고    scopus 로고
    • Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis
    • B.S. Oemar, M.R. Tschudi, N. Godoy, V. Brovkovich, T. Malinski, T.F. Lüscher, Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis, Circulation 97 (1998) 2494-2498.
    • (1998) Circulation , vol.97 , pp. 2494-2498
    • Oemar, B.S.1    Tschudi, M.R.2    Godoy, N.3    Brovkovich, V.4    Malinski, T.5    Lüscher, T.F.6
  • 14
    • 0029994360 scopus 로고    scopus 로고
    • Explanted vein grafts with an intact endothelium demonstrate reduced focal expression of endothelial nitric oxide synthase specific to atherosclerotic sites
    • L.D. Buttery, A.H. Chester, D.R. Springall, J.A. Borland, T. Michel, M.H. Yacoub, J.M. Polak, Explanted vein grafts with an intact endothelium demonstrate reduced focal expression of endothelial nitric oxide synthase specific to atherosclerotic sites, J. Pathol. 179 (1996) 197-203.
    • (1996) J. Pathol. , vol.179 , pp. 197-203
    • Buttery, L.D.1    Chester, A.H.2    Springall, D.R.3    Borland, J.A.4    Michel, T.5    Yacoub, M.H.6    Polak, J.M.7
  • 17
    • 0033967215 scopus 로고    scopus 로고
    • Cardiovascular dysfunction in hypercholesterolemia associated with enhanced formation of AT1-receptor and of eicosanoids
    • M. Schwemmer, O. Sommer, R. Koeckerbauer, E. Bassenge, Cardiovascular dysfunction in hypercholesterolemia associated with enhanced formation of AT1-receptor and of eicosanoids, J. Cardiovasc. Pharmacol. Ther. 5 (2000) 59-68.
    • (2000) J. Cardiovasc. Pharmacol. Ther. , vol.5 , pp. 59-68
    • Schwemmer, M.1    Sommer, O.2    Koeckerbauer, R.3    Bassenge, E.4
  • 18
    • 0037022256 scopus 로고    scopus 로고
    • Fundamentals of endothelial function for the clinical cardiologist
    • S. Verma, T.J. Anderson, Fundamentals of endothelial function for the clinical cardiologist, Circulation 105 (2002) 546-549.
    • (2002) Circulation , vol.105 , pp. 546-549
    • Verma, S.1    Anderson, T.J.2
  • 20
    • 0035098023 scopus 로고    scopus 로고
    • Effect of chronic insulin treatment on NO production and endothelium-dependent relaxation in aortae from established STZ-induced diabetic rats
    • T. Kobayashi, K. Kamata, Effect of chronic insulin treatment on NO production and endothelium-dependent relaxation in aortae from established STZ-induced diabetic rats, Atherosclerosis 155 (2001) 313-320.
    • (2001) Atherosclerosis , vol.155 , pp. 313-320
    • Kobayashi, T.1    Kamata, K.2
  • 21
    • 0034067388 scopus 로고    scopus 로고
    • Neuronal and endothelial nitric oxide synthase expression in outer medulla of streptozotocin-induced diabetic rat kidney
    • S.J. Shin, F.J. Lai, J.D. Wen, P.J. Hsiao, M.C. Hsieh, T.F. Tzeng, H.C. Chen, J.Y. Guh, J.H. Tsai, Neuronal and endothelial nitric oxide synthase expression in outer medulla of streptozotocin-induced diabetic rat kidney, Diabetologia 43 (2000) 649-659.
    • (2000) Diabetologia , vol.43 , pp. 649-659
    • Shin, S.J.1    Lai, F.J.2    Wen, J.D.3    Hsiao, P.J.4    Hsieh, M.C.5    Tzeng, T.F.6    Chen, H.C.7    Guh, J.Y.8    Tsai, J.H.9
  • 22
    • 0036174019 scopus 로고    scopus 로고
    • Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo
    • A.M. Joussen, V. Poulaki, W. Qin, B. Kirchhof, N. Mitsiades, S.J. Wiegand, J. Rudge, G.D. Yancopoulos, A.P. Adamis, Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo, Am. J. Pathol. 160 (2002) 501-509.
    • (2002) Am. J. Pathol. , vol.160 , pp. 501-509
    • Joussen, A.M.1    Poulaki, V.2    Qin, W.3    Kirchhof, B.4    Mitsiades, N.5    Wiegand, S.J.6    Rudge, J.7    Yancopoulos, G.D.8    Adamis, A.P.9
  • 23
    • 0034890217 scopus 로고    scopus 로고
    • Constitutive nitric oxide synthase is associated with retinal vascular permeability in early diabetic rats
    • M. Takeda, F. Mori, A. Yoshida, A. Takamiya, S. Nakagomi, E. Sato, H. Kiyama, Constitutive nitric oxide synthase is associated with retinal vascular permeability in early diabetic rats, Diabetologia 44 (2001) 1043-1050.
    • (2001) Diabetologia , vol.44 , pp. 1043-1050
    • Takeda, M.1    Mori, F.2    Yoshida, A.3    Takamiya, A.4    Nakagomi, S.5    Sato, E.6    Kiyama, H.7
  • 24
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • F. Cosentino, K. Hishikawa, Z.S. Katusic, T.F. Lüscher, High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells, Circulation 96 (1997) 25-28.
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Lüscher, T.F.4
  • 25
    • 0033867239 scopus 로고    scopus 로고
    • Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression
    • Y. Ding, N.D. Vaziri, R. Coulson, V.S. Kamanna, D.D. Roh, Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression, Am. J. Physiol. 279 (2000) E11-E17.
    • (2000) Am. J. Physiol. , vol.279 , pp. E11-E17
    • Ding, Y.1    Vaziri, N.D.2    Coulson, R.3    Kamanna, V.S.4    Roh, D.D.5
  • 26
    • 0031831261 scopus 로고    scopus 로고
    • Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products
    • U. Chakravarthy, R.G. Hayes, A.W. Stitt, E. McAuley, D.B. Archer, Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products, Diabetes 47 (1998) 945-952.
    • (1998) Diabetes , vol.47 , pp. 945-952
    • Chakravarthy, U.1    Hayes, R.G.2    Stitt, A.W.3    McAuley, E.4    Archer, D.B.5
  • 28
    • 0034616273 scopus 로고    scopus 로고
    • Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity
    • X.L. Wang, A.S. Sim, M.X. Wang, G.A. Murrell, B. Trudinger, J. Wang, Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity, FEBS Lett. 471 (2000) 45-50.
    • (2000) FEBS Lett. , vol.471 , pp. 45-50
    • Wang, X.L.1    Sim, A.S.2    Wang, M.X.3    Murrell, G.A.4    Trudinger, B.5    Wang, J.6
  • 29
    • 0032209539 scopus 로고    scopus 로고
    • Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells
    • Y. Su, W. Han, C. Giraldo, Y. De Li, E.R. Block, Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells, Am. J. Respir. Cell. Mol. Biol. 19 (1998) 819-825.
    • (1998) Am. J. Respir. Cell. Mol. Biol. , vol.19 , pp. 819-825
    • Su, Y.1    Han, W.2    Giraldo, C.3    De Li, Y.4    Block, E.R.5
  • 30
    • 0032813017 scopus 로고    scopus 로고
    • Effects of cigarette smoke on nitric oxide synthase expression in the rat lung
    • J.L. Wright, J. Dai, K. Zay, K. Price, C.B. Gilks, A. Churg, Effects of cigarette smoke on nitric oxide synthase expression in the rat lung, Lab. Invest. 79 (1999) 975-983.
    • (1999) Lab. Invest. , vol.79 , pp. 975-983
    • Wright, J.L.1    Dai, J.2    Zay, K.3    Price, K.4    Gilks, C.B.5    Churg, A.6
  • 33
    • 0001599370 scopus 로고
    • Role of endothelium-derived nitric oxide in the regulation of blood pressure
    • D.D. Rees, R.M. Palmer, S. Moncada, Role of endothelium-derived nitric oxide in the regulation of blood pressure, Proc. Natl. Acad. Sci. USA 86 (1989) 3375-3378.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 34
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • R.D. Rudic, E.G. Shesely, N. Maeda, O. Smithies, S.S. Segal, W.C. Sessa, Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling, J. Clin. Invest. 101 (1998) 731-736.
    • (1998) J. Clin. Invest. , vol.101 , pp. 731-736
    • Rudic, R.D.1    Shesely, E.G.2    Maeda, N.3    Smithies, O.4    Segal, S.S.5    Sessa, W.C.6
  • 35
    • 0030793748 scopus 로고    scopus 로고
    • Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery
    • K.F. Lin, L. Chao, J. Chao, Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery, Hypertension 30 (1997) 307-313.
    • (1997) Hypertension , vol.30 , pp. 307-313
    • Lin, K.F.1    Chao, L.2    Chao, J.3
  • 36
    • 0033932483 scopus 로고    scopus 로고
    • Long-term effect of antihypertensive therapy with calcium antagonist or angiotensin converting enzyme inhibitor on serum nitrite/nitrate levels in human essential hypertension
    • H. Takase, M. Sugiyama, A. Nakazawa, K. Sato, R. Ueda, Y. Dohi, Long-term effect of antihypertensive therapy with calcium antagonist or angiotensin converting enzyme inhibitor on serum nitrite/nitrate levels in human essential hypertension, Arzneimittelforschung 50 (2000) 530-534.
    • (2000) Arzneimittelforschung , vol.50 , pp. 530-534
    • Takase, H.1    Sugiyama, M.2    Nakazawa, A.3    Sato, K.4    Ueda, R.5    Dohi, Y.6
  • 37
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • R.P. Lifton, A.G. Gharavi, D.S. Geller, Molecular mechanisms of human hypertension, Cell 104 (2001) 545-556.
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 38
    • 0032883019 scopus 로고    scopus 로고
    • The molecular basis of hypertension
    • D.L. Garbers, S.K. Dubois, The molecular basis of hypertension, Annu. Rev. Biochem. 68 (1999) 127-155.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 127-155
    • Garbers, D.L.1    Dubois, S.K.2
  • 41
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium
    • S. Kerr, M.J. Brosnan, M. Mclntyre, J.L. Reid, A.F. Dominiczak, C.A. Hamilton, Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium, Hypertension 33 (1999) 1353-1358.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McLntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 42
    • 0034917618 scopus 로고    scopus 로고
    • Compensatory up-regulation of nitric-oxide synthase isoforms in lead-induced hypertension; reversal by a superoxide dismutase-mimetic drug
    • N.D. Vaziri, Y. Ding, Z. Ni, Compensatory up-regulation of nitric-oxide synthase isoforms in lead-induced hypertension; reversal by a superoxide dismutase-mimetic drug, J. Pharmacol. Exp. Ther. 298 (2001) 679-685.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 679-685
    • Vaziri, N.D.1    Ding, Y.2    Ni, Z.3
  • 43
    • 0030955626 scopus 로고    scopus 로고
    • Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene
    • W. Steudel, F. Ichinose, P.L. Huang, W.E. Hurford, R.C. Jones, J.A. Bevan, M.C. Fishman, W.M. Zapol, Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene, Circ. Res. 81 (1997) 34-41.
    • (1997) Circ. Res. , vol.81 , pp. 34-41
    • Steudel, W.1    Ichinose, F.2    Huang, P.L.3    Hurford, W.E.4    Jones, R.C.5    Bevan, J.A.6    Fishman, M.C.7    Zapol, W.M.8
  • 44
    • 0028290543 scopus 로고
    • Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs
    • J.R. Fineman, J. Wong, F.C. Morin 3rd, L.M. Wild, S.J. Soifer, Chronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs, J. Clin. Invest. 93 (1994) 2675-2683.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2675-2683
    • Fineman, J.R.1    Wong, J.2    Morin, F.C.3    Wild, L.M.4    Soifer, S.J.5
  • 46
    • 0030017320 scopus 로고    scopus 로고
    • Adeno viral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats
    • S.P. Janssens, K.D. Bloch, Z. Nong, R.D. Gerard, P. Zoldhelyi, D. Collen, Adeno viral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats, J. Clin. Invest. 98 (1996) 317-324.
    • (1996) J. Clin. Invest. , vol.98 , pp. 317-324
    • Janssens, S.P.1    Bloch, K.D.2    Nong, Z.3    Gerard, R.D.4    Zoldhelyi, P.5    Collen, D.6
  • 47
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • A. Giaid, D. Saleh, Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension, N. Engl. J. Med. 333 (1995) 214-221.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 48
    • 0031856005 scopus 로고    scopus 로고
    • High expression of endothelial nitric oxide synthase in plexiform lesions of pulmonary hypertension
    • N.A. Mason, D.R. Springall, M. Burke, J. Pollock, G. Mikhail, M.H. Yacoub, J.M. Polak, High expression of endothelial nitric oxide synthase in plexiform lesions of pulmonary hypertension, J. Pathol. 185 (1998) 313-318.
    • (1998) J. Pathol. , vol.185 , pp. 313-318
    • Mason, N.A.1    Springall, D.R.2    Burke, M.3    Pollock, J.4    Mikhail, G.5    Yacoub, M.H.6    Polak, J.M.7
  • 49
    • 0030954154 scopus 로고    scopus 로고
    • Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension
    • P.W. Shaul, I.S. Yuhanna, Z. German, Z. Chen, R.H. Steinhorn, F.C. Morin 3rd, Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension, Am. J. Physiol. 272 (1997) L1005-L1012.
    • (1997) Am. J. Physiol. , vol.272 , pp. L1005-L1012
    • Shaul, P.W.1    Yuhanna, I.S.2    German, Z.3    Chen, Z.4    Steinhorn, R.H.5    Morin, F.C.6
  • 50
    • 0030979142 scopus 로고    scopus 로고
    • Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus
    • E. Villamor, T.D. Le Cras, M.P. Koran, A.C. Halbower, R.M. Tuder, S.H. Abman, Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus, Am. J. Physiol. 272 (1997) L1013-L1020.
    • (1997) Am. J. Physiol. , vol.272 , pp. L1013-L1020
    • Villamor, E.1    Le Cras, T.D.2    Koran, M.P.3    Halbower, A.C.4    Tuder, R.M.5    Abman, S.H.6
  • 51
    • 0033839977 scopus 로고    scopus 로고
    • Early abnormalities of pulmonary vascular development in the Fawn-Hooded rat raised at Denver's altitude
    • T.D. Le Cras, D.H. Kim, N.E. Markham, A.S. Abman, Early abnormalities of pulmonary vascular development in the Fawn-Hooded rat raised at Denver's altitude, Am. J. Physiol. Lung Cell. Mol. Physiol. 279 (2000) L283-L291.
    • (2000) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.279 , pp. L283-L291
    • Le Cras, T.D.1    Kim, D.H.2    Markham, N.E.3    Abman, A.S.4
  • 53
    • 0035928753 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats
    • S. Kanno, Y.J. Wu, P.C. Lee, T.R. Billiar, C. Ho, Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats, Circulation 104 (2001) 945-950.
    • (2001) Circulation , vol.104 , pp. 945-950
    • Kanno, S.1    Wu, Y.J.2    Lee, P.C.3    Billiar, T.R.4    Ho, C.5
  • 55
    • 0027371195 scopus 로고
    • Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats
    • Z.G. Zhang, M. Chopp, C. Zaloga, J.S. Pollock, U. Förstermann, Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats, Stroke 24 (1993) 2016-2021.
    • (1993) Stroke , vol.24 , pp. 2016-2021
    • Zhang, Z.G.1    Chopp, M.2    Zaloga, C.3    Pollock, J.S.4    Förstermann, U.5
  • 57
    • 0034648090 scopus 로고    scopus 로고
    • Decrease of endothelial nitric oxide synthase in stroke-prone spontaneously hypertensive rat cerebral cortex
    • S. Kimoto-Kinoshita, S. Nishida, T.T. Tomura, Decrease of endothelial nitric oxide synthase in stroke-prone spontaneously hypertensive rat cerebral cortex, Neurosci. Lett. 288 (2000) 103-106.
    • (2000) Neurosci. Lett. , vol.288 , pp. 103-106
    • Kimoto-Kinoshita, S.1    Nishida, S.2    Tomura, T.T.3
  • 60
    • 0032826065 scopus 로고    scopus 로고
    • Neuroprotective properties of statins in cerebral ischemia and stroke
    • C.J. Vaughan, N. Delanty, Neuroprotective properties of statins in cerebral ischemia and stroke, Stroke 30 (1999) 1969-1973.
    • (1999) Stroke , vol.30 , pp. 1969-1973
    • Vaughan, C.J.1    Delanty, N.2
  • 64
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life
    • M. Yoshizumi, M.A. Perrella, J.C. Burnett Jr., M.E. Lee, Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life, Circ. Res. 73 (1993) 205-209.
    • (1993) Circ. Res. , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perrella, M.A.2    Burnett, J.C.3    Lee, M.E.4
  • 65
    • 0032211062 scopus 로고    scopus 로고
    • Increased expression of constitutive nitric oxide synthase III, but not inducible nitric oxide synthase II, in human heart failure
    • B. Stein, T. Eschenhagen, J. Rudiger, H. Scholz, U. Förstermann, I. Gath, Increased expression of constitutive nitric oxide synthase III, but not inducible nitric oxide synthase II, in human heart failure, J. Am. Coll. Cardiol. 32 (1998) 1179-1186.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 1179-1186
    • Stein, B.1    Eschenhagen, T.2    Rudiger, J.3    Scholz, H.4    Förstermann, U.5    Gath, I.6
  • 66
    • 0029745968 scopus 로고    scopus 로고
    • Regulation of human endothelial nitric oxide synthase by hypoxia and inflammation in human pulmonary arteries - Implications for the therapy of pulmonary hypertension in COPD patients
    • R. Ziesche, V. Petkov, W. Mosgoller, L.H. Block, Regulation of human endothelial nitric oxide synthase by hypoxia and inflammation in human pulmonary arteries - Implications for the therapy of pulmonary hypertension in COPD patients, Acta Anaesthesiol. Scand. Suppl. 109 (1996) 97-98.
    • (1996) Acta Anaesthesiol. Scand. Suppl. , vol.109 , pp. 97-98
    • Ziesche, R.1    Petkov, V.2    Mosgoller, W.3    Block, L.H.4
  • 67
    • 0029312594 scopus 로고
    • The effects of hypoxia on nitric oxide synthase activity and mRNA expression of pulmonary artery endothelial cells in pigs
    • A. Dai, Z. Zhang, R. Niu, The effects of hypoxia on nitric oxide synthase activity and mRNA expression of pulmonary artery endothelial cells in pigs, Chung Hua Chieh Ho Ho Hu Hsi Tsa Chih 18 (1995) 164-166.
    • (1995) Chung Hua Chieh Ho Ho Hu Hsi Tsa Chih , vol.18 , pp. 164-166
    • Dai, A.1    Zhang, Z.2    Niu, R.3
  • 69
    • 0029872411 scopus 로고    scopus 로고
    • Oxygen upregulates nitric oxide synthase gene expression in ovine fetal pulmonary artery endothelial cells
    • A.J. North, K.S. Lau, T.S. Brannon, L.C. Wu, L.B. Wells, Z. German, P.W. Shaul, Oxygen upregulates nitric oxide synthase gene expression in ovine fetal pulmonary artery endothelial cells, Am. J. Physiol. 270 (1996) L643-L649.
    • (1996) Am. J. Physiol. , vol.270 , pp. L643-L649
    • North, A.J.1    Lau, K.S.2    Brannon, T.S.3    Wu, L.C.4    Wells, L.B.5    German, Z.6    Shaul, P.W.7
  • 70
    • 0027938194 scopus 로고
    • Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
    • L.P. McQuillan, G.K. Leung, P.A. Marsden, S.K. Kostyk, S. Kourembanas, Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms, Am. J. Physiol. 36 (1994) H1921-H1927.
    • (1994) Am. J. Physiol. , vol.36 , pp. H1921-H1927
    • McQuillan, L.P.1    Leung, G.K.2    Marsden, P.A.3    Kostyk, S.K.4    Kourembanas, S.5
  • 71
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase
    • U. Laufs, V.L. Fata, J.K. Liao, Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase, J. Biol. Chem. 272 (1997) 31725-31729.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31725-31729
    • Laufs, U.1    Fata, V.L.2    Liao, J.K.3
  • 72
    • 0029948575 scopus 로고    scopus 로고
    • Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells
    • M.W. Phelan, D.V. Faller, Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells, J. Cell. Physiol. 167 (1996) 469-476.
    • (1996) J. Cell. Physiol. , vol.167 , pp. 469-476
    • Phelan, M.W.1    Faller, D.V.2
  • 74
    • 0033966770 scopus 로고    scopus 로고
    • Endothelial cell regulation of nitric oxide production during hypoxia in coronary microvessels and epicardial arteries
    • J.M. Justice, M.A. Tanner, P.R. Myers, Endothelial cell regulation of nitric oxide production during hypoxia in coronary microvessels and epicardial arteries, J. Cell. Physiol. 182 (2000) 359-365.
    • (2000) J. Cell. Physiol. , vol.182 , pp. 359-365
    • Justice, J.M.1    Tanner, M.A.2    Myers, P.R.3
  • 75
    • 0034737826 scopus 로고    scopus 로고
    • Downregulation of endothelial nitric oxide synthase in rat aorta after prolonged hypoxia in vivo
    • M. Toporsian, K. Govindaraju, M. Nagi, D. Eidelman, G. Thibault, M.E. Ward, Downregulation of endothelial nitric oxide synthase in rat aorta after prolonged hypoxia in vivo, Circ. Res. 86 (2000) 671-675.
    • (2000) Circ. Res. , vol.86 , pp. 671-675
    • Toporsian, M.1    Govindaraju, K.2    Nagi, M.3    Eidelman, D.4    Thibault, G.5    Ward, M.E.6
  • 77
    • 0030023029 scopus 로고    scopus 로고
    • Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung
    • T.D. Le Cras, C. Xue, A. Rengasamy, R.A. Johns, Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung, Am. J. Physiol. 270 (1996) L164-L170.
    • (1996) Am. J. Physiol. , vol.270 , pp. L164-L170
    • Le Cras, T.D.1    Xue, C.2    Rengasamy, A.3    Johns, R.A.4
  • 79
    • 0029957529 scopus 로고    scopus 로고
    • Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat
    • C. Xue, R.A. Johns, Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat, Hypertension 28 (1996) 743-753.
    • (1996) Hypertension , vol.28 , pp. 743-753
    • Xue, C.1    Johns, R.A.2
  • 80
    • 0033728055 scopus 로고    scopus 로고
    • Accumulation of nitrotyrosine correlates with endothelial NO synthase in pulmonary resistance arteries during chronic hypoxia in the rat
    • A.T. Demiryurek, M.R. Karamsetty, A.R. McPhaden, R.M. Wadsworth, K.A. Kane, M.R. MacLean, Accumulation of nitrotyrosine correlates with endothelial NO synthase in pulmonary resistance arteries during chronic hypoxia in the rat, Pulm. Pharmacol. Ther. 13 (2000) 157-165.
    • (2000) Pulm. Pharmacol. Ther. , vol.13 , pp. 157-165
    • Demiryurek, A.T.1    Karamsetty, M.R.2    McPhaden, A.R.3    Wadsworth, R.M.4    Kane, K.A.5    MacLean, M.R.6
  • 81
    • 0032988309 scopus 로고    scopus 로고
    • Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia
    • T.C. Resta, L.G. Chicoine, J.L. Omdahl, B.R. Walker, Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia, Am. J. Physiol. 276 (1999) H699-H708.
    • (1999) Am. J. Physiol. , vol.276 , pp. H699-H708
    • Resta, T.C.1    Chicoine, L.G.2    Omdahl, J.L.3    Walker, B.R.4
  • 83
    • 0030779819 scopus 로고    scopus 로고
    • Decreased nitric-oxide synthase activity causes impaired endothelium-dependent relaxation in the postischemic heart
    • R.R. Giraldez, A. Panda, Y. Xia, S.P. Sanders, J.L. Zweier, Decreased nitric-oxide synthase activity causes impaired endothelium-dependent relaxation in the postischemic heart, J. Biol. Chem. 212 (1997) 21420-21426.
    • (1997) J. Biol. Chem. , vol.212 , pp. 21420-21426
    • Giraldez, R.R.1    Panda, A.2    Xia, Y.3    Sanders, S.P.4    Zweier, J.L.5
  • 84
    • 0034832915 scopus 로고    scopus 로고
    • TGF-β(1) modulates NOS expression and phosphorylation of Akt/PKB in rat myocytes exposed to hypoxia-reoxygenation
    • H. Chen, D. Li, T. Saldeen, J.L. Mehta, TGF-β(1) modulates NOS expression and phosphorylation of Akt/PKB in rat myocytes exposed to hypoxia-reoxygenation, Am. J. Physiol. 281 (2001) H1035-H1039.
    • (2001) Am. J. Physiol. , vol.281 , pp. H1035-H1039
    • Chen, H.1    Li, D.2    Saldeen, T.3    Mehta, J.L.4
  • 85
    • 0034942037 scopus 로고    scopus 로고
    • Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: An ex vivo study in isolated working rat hearts
    • P. Di Napoli, A. Antonio Taccardi, A. Grilli, R. Spina, M. Felaco, A. Barsotti, R. De Caterina, Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: An ex vivo study in isolated working rat hearts, Cardiovasc. Res. 51 (2001) 283-293.
    • (2001) Cardiovasc. Res. , vol.51 , pp. 283-293
    • Di Napoli, P.1    Antonio Taccardi, A.2    Grilli, A.3    Spina, R.4    Felaco, M.5    Barsotti, A.6    De Caterina, R.7
  • 86
    • 0034983144 scopus 로고    scopus 로고
    • Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase
    • M. Joyce, C.J. Kelly, G. Chen, D.J. Bouchier-Hayes, Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase, Eur. J. Vasc. Endovasc. Surg. 21 (2001) 295-300.
    • (2001) Eur. J. Vasc. Endovasc. Surg. , vol.21 , pp. 295-300
    • Joyce, M.1    Kelly, C.J.2    Chen, G.3    Bouchier-Hayes, D.J.4
  • 87
    • 0033969745 scopus 로고    scopus 로고
    • Infarct size and nitric oxide synthase in murine myocardium
    • M.S. Sumeray, D.D. Rees, D.M. Yellon, Infarct size and nitric oxide synthase in murine myocardium, J. Mol. Cell. Cardiol. 32 (2000) 35-42.
    • (2000) J. Mol. Cell. Cardiol. , vol.32 , pp. 35-42
    • Sumeray, M.S.1    Rees, D.D.2    Yellon, D.M.3
  • 88
    • 0030006173 scopus 로고    scopus 로고
    • Aging progressively impairs endothelium-dependent vasodilation in forearm resistance vessels of humans
    • M. Gerhard, M.A. Roddy, S.J. Creager, M.A. Creager, Aging progressively impairs endothelium-dependent vasodilation in forearm resistance vessels of humans, Hypertension 27 (1996) 849-853.
    • (1996) Hypertension , vol.27 , pp. 849-853
    • Gerhard, M.1    Roddy, M.A.2    Creager, S.J.3    Creager, M.A.4
  • 91
    • 0031886546 scopus 로고    scopus 로고
    • Alterations of nitric oxide synthase expression with aging and hypertension in rats
    • T.C. Chou, M.H. Yen, C.Y. Li, Y.A. Ding, Alterations of nitric oxide synthase expression with aging and hypertension in rats, Hypertension 31 (1998) 643-648.
    • (1998) Hypertension , vol.31 , pp. 643-648
    • Chou, T.C.1    Yen, M.H.2    Li, C.Y.3    Ding, Y.A.4
  • 92
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • T. Finkel, N.J. Holbrook, Oxidants, oxidative stress and the biology of ageing, Nature 408 (2000) 239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 94
    • 0034623823 scopus 로고    scopus 로고
    • The oxidative paradox: Another piece in the puzzle
    • C. Patterson, N.R. Madamanchi, M.S. Runge, The oxidative paradox: Another piece in the puzzle, Circ. Res. 87 (2000) 1074-1076.
    • (2000) Circ. Res. , vol.87 , pp. 1074-1076
    • Patterson, C.1    Madamanchi, N.R.2    Runge, M.S.3
  • 96
    • 0033952940 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
    • G.R. Drummond, H. Cai, M.E. Davis, S. Ramasamy, D.G. Harrison, Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide, Circ. Res. 86 (2000) 347-354.
    • (2000) Circ. Res. , vol.86 , pp. 347-354
    • Drummond, G.R.1    Cai, H.2    Davis, M.E.3    Ramasamy, S.4    Harrison, D.G.5
  • 97
    • 0035724654 scopus 로고    scopus 로고
    • Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2+)/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway
    • H. Cai, M.E. Davis, G.R. Drummond, D.G. Harrison, Induction of endothelial NO synthase by hydrogen peroxide via a Ca(2+)/calmodulin-dependent protein kinase II/janus kinase 2-dependent pathway, Arterioscler. Thromb. Vasc. Biol. 21 (2001) 1571-1576.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1571-1576
    • Cai, H.1    Davis, M.E.2    Drummond, G.R.3    Harrison, D.G.4
  • 99
    • 0034614284 scopus 로고    scopus 로고
    • Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability
    • T. Münzel, H. Li, H. Mollnau, U. Hink, E. Matheis, M. Hartmann, M. Oelze, M. Skatchkov, A. Warnholtz, L. Duncker, T. Meinertz, U. Förstermann, Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability, Circ. Res. 86 (2000) E7-E12.
    • (2000) Circ. Res. , vol.86 , pp. E7-E12
    • Münzel, T.1    Li, H.2    Mollnau, H.3    Hink, U.4    Matheis, E.5    Hartmann, M.6    Oelze, M.7    Skatchkov, M.8    Warnholtz, A.9    Duncker, L.10    Meinertz, T.11    Förstermann, U.12
  • 101
    • 0037155131 scopus 로고    scopus 로고
    • Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway
    • S.R. Thomas, K. Chen, J.F. Keaney Jr., Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway, J. Biol. Chem. 211 (2002) 6017-6024.
    • (2002) J. Biol. Chem. , vol.211 , pp. 6017-6024
    • Thomas, S.R.1    Chen, K.2    Keaney, J.F.3
  • 102
    • 0034625348 scopus 로고    scopus 로고
    • Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase
    • H.M. Abu Soud, K. Ichimori, A. Presta, D.J. Stuehr, Electron transfer, oxygen binding, and nitric oxide feedback inhibition in endothelial nitric-oxide synthase, J. Biol. Chem. 215 (2000) 17349-17357.
    • (2000) J. Biol. Chem. , vol.215 , pp. 17349-17357
    • Abu Soud, H.M.1    Ichimori, K.2    Presta, A.3    Stuehr, D.J.4
  • 103
    • 0033567065 scopus 로고    scopus 로고
    • Enzymatic function of nitric oxide synthases
    • P.J. Andrew, B. Mayer, Enzymatic function of nitric oxide synthases, Cardiovasc. Res. 43 (1999) 521-531.
    • (1999) Cardiovasc. Res. , vol.43 , pp. 521-531
    • Andrew, P.J.1    Mayer, B.2
  • 104
    • 0034703358 scopus 로고    scopus 로고
    • Nitric oxide synthases catalyze superoxide formation
    • B. Mayer, Nitric oxide synthases catalyze superoxide formation, FEBS Lett. 481 (2000) 304.
    • (2000) FEBS Lett. , vol.481 , pp. 304
    • Mayer, B.1
  • 106
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Y. Xia, A.L. Tsai, V. Berka, J.L. Zweier, Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process, J. Biol. Chem. 213 (1998) 25804-25808.
    • (1998) J. Biol. Chem. , vol.213 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 109
    • 0035814951 scopus 로고    scopus 로고
    • Endothelial regulation of vasomotion in apoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
    • J.B. Laursen, M. Somers, S. Kurz, L. McCann, A. Warnholtz, B.A. Freeman, M. Tarpey, T. Fukai, D.G. Harrison, Endothelial regulation of vasomotion in apoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin, Circulation 103 (2001) 1282-1288.
    • (2001) Circulation , vol.103 , pp. 1282-1288
    • Laursen, J.B.1    Somers, M.2    Kurz, S.3    McCann, L.4    Warnholtz, A.5    Freeman, B.A.6    Tarpey, M.7    Fukai, T.8    Harrison, D.G.9
  • 111
    • 0027459585 scopus 로고
    • Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity
    • G. Werner-Felmayer, E.R. Werner, D. Fuchs, A. Hausen, G. Reibnegger, K. Schmidt, G. Weiss, H. Wachter, Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity, J. Biol. Chem. 268 (1993) 1842-1846.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1842-1846
    • Werner-Felmayer, G.1    Werner, E.R.2    Fuchs, D.3    Hausen, A.4    Reibnegger, G.5    Schmidt, K.6    Weiss, G.7    Wachter, H.8
  • 112
    • 0028196891 scopus 로고
    • Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity
    • P. Rosenkranz-Weiss, W.C. Sessa, S. Milstien, S. Kaufman, C.A. Watson, J.S. Pober, Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity, J. Clin. Invest. 93 (1994) 2236-2243.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2236-2243
    • Rosenkranz-Weiss, P.1    Sessa, W.C.2    Milstien, S.3    Kaufman, S.4    Watson, C.A.5    Pober, J.S.6
  • 113
    • 0031033321 scopus 로고    scopus 로고
    • Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin
    • G.M. Pieper, Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin, J. Cardiovasc. Pharmacol. 29 (1997) 8-15.
    • (1997) J. Cardiovasc. Pharmacol. , vol.29 , pp. 8-15
    • Pieper, G.M.1
  • 114
    • 0034730795 scopus 로고    scopus 로고
    • Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats
    • K. Shinozaki, Y. Nishio, T. Okamura, Y. Yoshida, H. Maegawa, H. Kojima, M. Masada, N. Toda, R. Kikkawa, A. Kashiwagi, Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats, Circ. Res. 87 (2000) 566-573.
    • (2000) Circ. Res. , vol.87 , pp. 566-573
    • Shinozaki, K.1    Nishio, Y.2    Okamura, T.3    Yoshida, Y.4    Maegawa, H.5    Kojima, H.6    Masada, M.7    Toda, N.8    Kikkawa, R.9    Kashiwagi, A.10
  • 116
    • 0034602878 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
    • T. Heitzer, C. Brockhoff, B. Mayer, A. Warnholtz, H. Mollnau, S. Henne, T. Meinertz, T. Münzel, Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase, Circ. Res. 86 (2000) E36-E41.
    • (2000) Circ. Res. , vol.86 , pp. E36-E41
    • Heitzer, T.1    Brockhoff, C.2    Mayer, B.3    Warnholtz, A.4    Mollnau, H.5    Henne, S.6    Meinertz, T.7    Münzel, T.8
  • 117
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • S. Milstien, Z. Katusic, Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function, Biochem. Biophys. Res. Commun. 263 (1999) 681-684.
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 119
    • 0035726142 scopus 로고    scopus 로고
    • Supplemention with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats
    • H.-J. Hong, G. Hsiao, T.-H. Cheng, M.-H. Yen, Supplemention with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats, Hypertension 38 (2001) 1044-1048.
    • (2001) Hypertension , vol.38 , pp. 1044-1048
    • Hong, H.-J.1    Hsiao, G.2    Cheng, T.-H.3    Yen, M.-H.4
  • 120
    • 0033210904 scopus 로고    scopus 로고
    • Statins and blockers of the renin-angiotensin system: Vascular protection beyond their primary mode of action
    • A. Faggiotto, R. Paoletti, Statins and blockers of the renin-angiotensin system: Vascular protection beyond their primary mode of action, Hypertension 34 (1999) 987-996.
    • (1999) Hypertension , vol.34 , pp. 987-996
    • Faggiotto, A.1    Paoletti, R.2
  • 121
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • U. Laufs, V. La Fata, J. Plutzky, J.K. Liao, Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors, Circulation 97 (1998) 1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 122
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • U. Laufs, J.K. Liao, Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase, J. Biol. Chem. 273 (1998) 24266-24271.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 124
    • 0343048978 scopus 로고    scopus 로고
    • Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
    • A.H. Wagner, T. Kohler, U. Ruckschloss, I. Just, M. Hecker, Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation, Arterioscler. Thromb. Vasc. Biol. 20 (2000) 61-69.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 61-69
    • Wagner, A.H.1    Kohler, T.2    Ruckschloss, U.3    Just, I.4    Hecker, M.5
  • 125
    • 0035089910 scopus 로고    scopus 로고
    • A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects - The relevance of endothelial nitric oxide synthase and superoxide anion scavenging action
    • D. Sumi, T. Hayashi, N.K. Thakur, M. Jayachandran, Y. Asai, H. Kano, H. Matsui, A. Iguchi, A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects - The relevance of endothelial nitric oxide synthase and superoxide anion scavenging action, Atherosclerosis 155 (2001) 347-357.
    • (2001) Atherosclerosis , vol.155 , pp. 347-357
    • Sumi, D.1    Hayashi, T.2    Thakur, N.K.3    Jayachandran, M.4    Asai, Y.5    Kano, H.6    Matsui, H.7    Iguchi, A.8
  • 126
    • 0032753626 scopus 로고    scopus 로고
    • Atorvastatin increases ecNOS levels in human platelets of hyperlipidemic subjects
    • M. Tannous, R. Cheung, A. Vignini, B. Mutus, Atorvastatin increases ecNOS levels in human platelets of hyperlipidemic subjects, Thromb. Haemost. 82 (1999) 1390-1394.
    • (1999) Thromb. Haemost. , vol.82 , pp. 1390-1394
    • Tannous, M.1    Cheung, R.2    Vignini, A.3    Mutus, B.4
  • 127
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • M. Endres, U. Laufs, Z. Huang, T. Nakamura, P. Huang, M.A. Moskowitz, J.K. Liao, Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase, Proc. Natl. Acad. Sci. USA 95 (1998) 8880-8885.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3    Nakamura, T.4    Huang, P.5    Moskowitz, M.A.6    Liao, J.K.7
  • 128
    • 0033800718 scopus 로고    scopus 로고
    • Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
    • U. Laufs, K. Gertz, P. Huang, G. Nickenig, M. Bohm, U. Dirnagl, M. Endres, Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice, Stroke 31 (2000) 2442-2449.
    • (2000) Stroke , vol.31 , pp. 2442-2449
    • Laufs, U.1    Gertz, K.2    Huang, P.3    Nickenig, G.4    Bohm, M.5    Dirnagl, U.6    Endres, M.7
  • 129
    • 0035073930 scopus 로고    scopus 로고
    • Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice
    • S. Amin-Hanjani, N.E. Stagliano, M. Yamada, P.L. Huang, J.K. Liao, M.A. Moskowitz, Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice, Stroke 52 (2001) 980-986.
    • (2001) Stroke , vol.52 , pp. 980-986
    • Amin-Hanjani, S.1    Stagliano, N.E.2    Yamada, M.3    Huang, P.L.4    Liao, J.K.5    Moskowitz, M.A.6
  • 130
    • 0032896636 scopus 로고    scopus 로고
    • Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions
    • W.H. Kaesemeyer, R.B. Caldwell, J. Huang, R.W. Caldwell, Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions, J. Am. Coll. Cardiol. 33 (1999) 234-241.
    • (1999) J. Am. Coll. Cardiol. , vol.33 , pp. 234-241
    • Kaesemeyer, W.H.1    Caldwell, R.B.2    Huang, J.3    Caldwell, R.W.4
  • 131
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • S. Wassmann, U. Laufs, A.T. Baumer, K. Muller, K. Ahlbory, W. Linz, G. Itter, R. Rosen, M. Bohm, G. Nickenig, HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species, Hypertension 37 (2001) 1450-1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3    Muller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rosen, R.8    Bohm, M.9    Nickenig, G.10
  • 132
    • 0032719311 scopus 로고    scopus 로고
    • Anti-atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high-cholesterol diet
    • M. Miyazaki, H. Sakonjo, S. Takai, Anti-atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high-cholesterol diet, Br. J. Pharmacol. 128 (1999) 523-529.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 523-529
    • Miyazaki, M.1    Sakonjo, H.2    Takai, S.3
  • 135
    • 0032844079 scopus 로고    scopus 로고
    • Late treatment with ramipril increases survival in old spontaneously hypertensive rats
    • W. Linz, P. Wohlfart, B.A. Schoelkens, R.H. Becker, T. Malinski, G. Wiemer, Late treatment with ramipril increases survival in old spontaneously hypertensive rats, Hypertension 34 (1999) 291-295.
    • (1999) Hypertension , vol.34 , pp. 291-295
    • Linz, W.1    Wohlfart, P.2    Schoelkens, B.A.3    Becker, R.H.4    Malinski, T.5    Wiemer, G.6
  • 136
    • 0030689824 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats
    • G. Wiemer, W. Linz, S. Hatrik, B.A. Scholkens, T. Malinski, Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats, Hypertension 30 (1997) 1183-1190.
    • (1997) Hypertension , vol.30 , pp. 1183-1190
    • Wiemer, G.1    Linz, W.2    Hatrik, S.3    Scholkens, B.A.4    Malinski, T.5
  • 138
    • 0033461195 scopus 로고    scopus 로고
    • Effects of imidapril on NOS expression and myocardial remodelling in failing heart of Dahl salt-sensitive hypertensive rats
    • N. Kobayashi, T. Higashi, K. Hara, H. Shirataki, H. Matsuoka, Effects of imidapril on NOS expression and myocardial remodelling in failing heart of Dahl salt-sensitive hypertensive rats, Cardiovasc. Res. 44 (1999) 518-526.
    • (1999) Cardiovasc. Res. , vol.44 , pp. 518-526
    • Kobayashi, N.1    Higashi, T.2    Hara, K.3    Shirataki, H.4    Matsuoka, H.5
  • 139
    • 0034682662 scopus 로고    scopus 로고
    • Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure: Role of nitric oxide, prostanoids, oxidant stress, and bradykinin
    • R. Varin, P. Mulder, F. Tamion, V. Richard, J.P. Henry, F. Lallemand, G. Lerebours, C. Thuillez, Improvement of endothelial function by chronic angiotensin-converting enzyme inhibition in heart failure: Role of nitric oxide, prostanoids, oxidant stress, and bradykinin, Circulation 102 (2000) 351-356.
    • (2000) Circulation , vol.102 , pp. 351-356
    • Varin, R.1    Mulder, P.2    Tamion, F.3    Richard, V.4    Henry, J.P.5    Lallemand, F.6    Lerebours, G.7    Thuillez, C.8
  • 140
    • 0032752107 scopus 로고    scopus 로고
    • Plasma levels of nitric oxide and related vasoactive factors following long-term treatment with angiotensin-converting enzyme inhibitor in patients with essential hypertension
    • M. Kohno, K. Yokokawa, M. Minami, K. Yasunari, K. Maeda, H. Kano, T. Hanehira, J. Yoshikawa, Plasma levels of nitric oxide and related vasoactive factors following long-term treatment with angiotensin-converting enzyme inhibitor in patients with essential hypertension, Metabolism 48 (1999) 1256-1259.
    • (1999) Metabolism , vol.48 , pp. 1256-1259
    • Kohno, M.1    Yokokawa, K.2    Minami, M.3    Yasunari, K.4    Maeda, K.5    Kano, H.6    Hanehira, T.7    Yoshikawa, J.8
  • 141
    • 0032819511 scopus 로고    scopus 로고
    • Enhanced angiotensin-converting enzyme activity and impaired endothelium-dependent vasodilation in aortae from hypertensive rats: Evidence for a causal link
    • R.M. Goetz, J. Holtz, Enhanced angiotensin-converting enzyme activity and impaired endothelium-dependent vasodilation in aortae from hypertensive rats: Evidence for a causal link, Clin. Sci. Colch. 97 (1999) 165-174.
    • (1999) Clin. Sci. Colch. , vol.97 , pp. 165-174
    • Goetz, R.M.1    Holtz, J.2
  • 143
    • 0034106595 scopus 로고    scopus 로고
    • Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats
    • W. Linz, H. Heitsch, B.A. Scholkens, G. Wiemer, Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats, Hypertension 35 (2000) 908-913.
    • (2000) Hypertension , vol.35 , pp. 908-913
    • Linz, W.1    Heitsch, H.2    Scholkens, B.A.3    Wiemer, G.4
  • 144
    • 0034074919 scopus 로고    scopus 로고
    • Effects of angiotensin II type 1 receptor antagonist on nitric oxide synthase expression and myocardial remodeling in Goldblatt hypertensive rats
    • T. Higashi, N. Kobayashi, K. Hara, H. Shirataki, H. Matsuoka, Effects of angiotensin II type 1 receptor antagonist on nitric oxide synthase expression and myocardial remodeling in Goldblatt hypertensive rats, J. Cardiovasc. Pharmacol. 35 (2000) 564-571.
    • (2000) J. Cardiovasc. Pharmacol. , vol.35 , pp. 564-571
    • Higashi, T.1    Kobayashi, N.2    Hara, K.3    Shirataki, H.4    Matsuoka, H.5
  • 145
    • 0034813223 scopus 로고    scopus 로고
    • TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive rats
    • N. Kobayashi, Y. Mori, S. Nakano, Y. Tsubokou, T. Kobayashi, H. Shirataki, H. Matsuoka, TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive rats, Atherosclerosis 158 (2001) 359-368.
    • (2001) Atherosclerosis , vol.158 , pp. 359-368
    • Kobayashi, N.1    Mori, Y.2    Nakano, S.3    Tsubokou, Y.4    Kobayashi, T.5    Shirataki, H.6    Matsuoka, H.7
  • 146
    • 0032991031 scopus 로고    scopus 로고
    • Nifedipine improves endothelial function in hypercholesterolemia, independently of an effect on blood pressure or plasma lipids
    • M.C. Verhaar, M.L. Honing, T. van Dam, M. Zwart, H.A. Koomans, J.J. Kastelein, T.J. Rabelink, Nifedipine improves endothelial function in hypercholesterolemia, independently of an effect on blood pressure or plasma lipids, Cardiovasc. Res. 42 (1999) 752-760.
    • (1999) Cardiovasc. Res. , vol.42 , pp. 752-760
    • Verhaar, M.C.1    Honing, M.L.2    Van Dam, T.3    Zwart, M.4    Koomans, H.A.5    Kastelein, J.J.6    Rabelink, T.J.7
  • 147
    • 0033978264 scopus 로고    scopus 로고
    • Pranidipine enhances the action of nitric oxide released from endothelial cells
    • J. Yang, K. Fukuo, S. Morimoto, T. Niinobu, T. Suhara, T. Ogihara, Pranidipine enhances the action of nitric oxide released from endothelial cells, Hypertension 35 (2000) 82-85.
    • (2000) Hypertension , vol.35 , pp. 82-85
    • Yang, J.1    Fukuo, K.2    Morimoto, S.3    Niinobu, T.4    Suhara, T.5    Ogihara, T.6
  • 148
    • 0035100975 scopus 로고    scopus 로고
    • Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension
    • S. Taddei, A. Virdis, L. Ghiadoni, A. Magagna, S. Favilla, A. Pompella, A. Salvetti, Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension, Hypertension 37 (2001) 943-948.
    • (2001) Hypertension , vol.37 , pp. 943-948
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Favilla, S.5    Pompella, A.6    Salvetti, A.7
  • 149
    • 0030693948 scopus 로고    scopus 로고
    • Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients
    • S. Taddei, A. Virdis, L. Ghiadoni, S. Uleri, A. Magagna, A. Salvetti, Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients, Hypertension 30 (1997) 1606-1612.
    • (1997) Hypertension , vol.30 , pp. 1606-1612
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Uleri, S.4    Magagna, A.5    Salvetti, A.6
  • 150
    • 0032885807 scopus 로고    scopus 로고
    • Dual mode of action of dihydropyridine calcium antagonists - A role for nitric oxide
    • S. Dhein, A. Salameh, R. Berkels, W. Klaus, Dual mode of action of dihydropyridine calcium antagonists - A role for nitric oxide, Drugs 58 (1999) 397-404.
    • (1999) Drugs , vol.58 , pp. 397-404
    • Dhein, S.1    Salameh, A.2    Berkels, R.3    Klaus, W.4
  • 153
    • 0031912146 scopus 로고    scopus 로고
    • Amlodipine releases nitric oxide from canine coronary microvessels: An unexpected mechanism of action of a calcium channel-blocking agent
    • X. Zhang, T.H. Hintze, Amlodipine releases nitric oxide from canine coronary microvessels: An unexpected mechanism of action of a calcium channel-blocking agent, Circulation 97 (1998) 576-580.
    • (1998) Circulation , vol.97 , pp. 576-580
    • Zhang, X.1    Hintze, T.H.2
  • 154
    • 0031724864 scopus 로고    scopus 로고
    • Calcium channel blockade enhances nitric oxide synthase expression by cultured endothelial cells
    • Y. Ding, N.D. Vaziri, Calcium channel blockade enhances nitric oxide synthase expression by cultured endothelial cells, Hypertension 32 (1998) 718-723.
    • (1998) Hypertension , vol.32 , pp. 718-723
    • Ding, Y.1    Vaziri, N.D.2
  • 155
    • 0032993366 scopus 로고    scopus 로고
    • Erythropoietin depresses nitric oxide synthase expression by human endothelial cells
    • X.Q. Wang, N.D. Vaziri, Erythropoietin depresses nitric oxide synthase expression by human endothelial cells, Hypertension 33 (1999) 894-899.
    • (1999) Hypertension , vol.33 , pp. 894-899
    • Wang, X.Q.1    Vaziri, N.D.2
  • 156
    • 0033959660 scopus 로고    scopus 로고
    • Nifedipine and diltiazem but not verapamil up-regulate endothelial nitric-oxide synthase expression
    • Y. Ding, N.D. Vaziri, Nifedipine and diltiazem but not verapamil up-regulate endothelial nitric-oxide synthase expression, J. Pharmacol. Exp. Ther. 292 (2000) 606-609.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 606-609
    • Ding, Y.1    Vaziri, N.D.2
  • 157
    • 0031724865 scopus 로고    scopus 로고
    • Nitric oxide metabolism in erythropoietin-inducedhypertension: Effect of calcium channel blockade
    • Z. Ni, X.Q. Wang, N.D. Vaziri, Nitric oxide metabolism in erythropoietin-inducedhypertension: Effect of calcium channel blockade, Hypertension 32 (1998) 724-729.
    • (1998) Hypertension , vol.32 , pp. 724-729
    • Ni, Z.1    Wang, X.Q.2    Vaziri, N.D.3
  • 158
    • 0031968667 scopus 로고    scopus 로고
    • Down-regulation of nitric oxide synthase in chronic renal insufficiency: Role of excess PTH
    • N.D. Vaziri, Z. Ni, X.Q. Wang, F. Oveisi, X.J. Zhou, Down-regulation of nitric oxide synthase in chronic renal insufficiency: Role of excess PTH, Am. J. Physiol. 274 (1998) F642-F649.
    • (1998) Am. J. Physiol. , vol.274 , pp. F642-F649
    • Vaziri, N.D.1    Ni, Z.2    Wang, X.Q.3    Oveisi, F.4    Zhou, X.J.5
  • 159
    • 0035123687 scopus 로고    scopus 로고
    • A calcium channel blocker, benidipine, inhibits intimal thickening in the carotid artery of mice by increasing nitric oxide production
    • T. Yamashita, S. Kawashima, M. Ozaki, Y. Rikitake, T. Hirase, N. Inoue, K. Hirata, M. Yokoyama, A calcium channel blocker, benidipine, inhibits intimal thickening in the carotid artery of mice by increasing nitric oxide production, J. Hypertens. 19 (2001) 451-458.
    • (2001) J. Hypertens. , vol.19 , pp. 451-458
    • Yamashita, T.1    Kawashima, S.2    Ozaki, M.3    Rikitake, Y.4    Hirase, T.5    Inoue, N.6    Hirata, K.7    Yokoyama, M.8
  • 160
  • 161
    • 0035045885 scopus 로고    scopus 로고
    • Lacidipine prevents endothelial dysfunction in salt-loaded stroke-prone hypertensive rats
    • P. Krenek, S. Salomone, J. Kyselovic, M. Wibo, N. Morel, T. Godfraind, Lacidipine prevents endothelial dysfunction in salt-loaded stroke-prone hypertensive rats, Hypertension 37 (2001) 1124-1128.
    • (2001) Hypertension , vol.37 , pp. 1124-1128
    • Krenek, P.1    Salomone, S.2    Kyselovic, J.3    Wibo, M.4    Morel, N.5    Godfraind, T.6
  • 162
    • 0032976441 scopus 로고    scopus 로고
    • Effects of two calcium channel blockers on messenger RNA expression of endothelin-1 and nitric oxide synthase in cardiovascular tissue of hypertensive rats
    • M. Naruse, A. Tanabe, T. Seki, C. Adachi, T. Yoshimoto, N. Mishina, T. Imaki, K. Naruse, R. Demura, H. Demura, Effects of two calcium channel blockers on messenger RNA expression of endothelin-1 and nitric oxide synthase in cardiovascular tissue of hypertensive rats, J. Hypertens. 17 (1999) 53-60.
    • (1999) J. Hypertens. , vol.17 , pp. 53-60
    • Naruse, M.1    Tanabe, A.2    Seki, T.3    Adachi, C.4    Yoshimoto, T.5    Mishina, N.6    Imaki, T.7    Naruse, K.8    Demura, R.9    Demura, H.10
  • 163
    • 0032887933 scopus 로고    scopus 로고
    • Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs
    • C.D. Fike, M.R. Kaplowitz, Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs, Am. J. Physiol. 277 (1999) L449-L456.
    • (1999) Am. J. Physiol. , vol.277 , pp. L449-L456
    • Fike, C.D.1    Kaplowitz, M.R.2
  • 164
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • J.S. Beckman, W.H. Koppenol, Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly, Am. J. Physiol. 271 (1996) C1424-C1437.
    • (1996) Am. J. Physiol. , vol.271 , pp. C1424-C1437
    • Beckman, J.S.1    Koppenol, W.H.2
  • 165
    • 0033022807 scopus 로고    scopus 로고
    • Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells
    • S. Ramasamy, G.R. Drummond, J. Ahn, M. Storek, J. Pohl, S. Parthasarathy, D.G. Harrison, Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells, Mol. Pharmacol. 56 (1999) 116-123.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 116-123
    • Ramasamy, S.1    Drummond, G.R.2    Ahn, J.3    Storek, M.4    Pohl, J.5    Parthasarathy, S.6    Harrison, D.G.7
  • 166
    • 0039550848 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates nitric oxide synthesis in endothelial cells
    • R. Heller, F. Munscher Paulig, R. Grabner, U. Till, L-ascorbic acid potentiates nitric oxide synthesis in endothelial cells, J. Biol. Chem. 274 (1999) 8254-8260.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8254-8260
    • Heller, R.1    Munscher Paulig, F.2    Grabner, R.3    Till, U.4
  • 167
    • 0035120543 scopus 로고    scopus 로고
    • Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells
    • T.A. Baker, S. Milstien, Z.S. Katusic, Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells, J. Cardiovasc. Pharmacol. 37 (2001) 333-338.
    • (2001) J. Cardiovasc. Pharmacol. , vol.37 , pp. 333-338
    • Baker, T.A.1    Milstien, S.2    Katusic, Z.S.3
  • 168
    • 0035808310 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin
    • R. Heller, A. Unbehaun, B. Schellenberg, B. Mayer, G. Werner-Felmayer, E.R. Werner, L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin, J. Biol. Chem. 276 (2001) 40-47.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40-47
    • Heller, R.1    Unbehaun, A.2    Schellenberg, B.3    Mayer, B.4    Werner-Felmayer, G.5    Werner, E.R.6
  • 169
    • 0034625391 scopus 로고    scopus 로고
    • Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin
    • A. Huang, J.A. Vita, R.C. Venema, J.F. Keaney Jr., Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin, J. Biol. Chem. 275 (2000) 17399-17406.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17399-17406
    • Huang, A.1    Vita, J.A.2    Venema, R.C.3    Keaney, J.F.4
  • 170
    • 0034190373 scopus 로고    scopus 로고
    • How does ascorbic acid prevent endothelial dysfunction
    • J.M. May, How does ascorbic acid prevent endothelial dysfunction, Free. Radic. Biol. Med. 28 (2000) 1421-1429.
    • (2000) Free. Radic. Biol. Med. , vol.28 , pp. 1421-1429
    • May, J.M.1
  • 171
  • 174
    • 0031723243 scopus 로고    scopus 로고
    • Effects of red and white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries
    • M. Flesch, A. Schwarz, M. Bohm, Effects of red and white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries, Am. J. Physiol. 275 (1998) H1183-H1190.
    • (1998) Am. J. Physiol. , vol.275 , pp. H1183-H1190
    • Flesch, M.1    Schwarz, A.2    Bohm, M.3
  • 175
    • 0011487226 scopus 로고    scopus 로고
    • Red wine increases the expression of human endothelial NO synthase (eNOS): A mechanism that may contribute to its beneficial cardiovascular effects
    • in press
    • T. Wallerath, D. Poleo, H. Li, U. Förstermann, Red wine increases the expression of human endothelial NO synthase (eNOS): A mechanism that may contribute to its beneficial cardiovascular effects, J. Am. Coll. Cardiol. (2002) in press.
    • (2002) J. Am. Coll. Cardiol.
    • Wallerath, T.1    Poleo, D.2    Li, H.3    Förstermann, U.4
  • 176
    • 0343114388 scopus 로고    scopus 로고
    • Structure-activity relationship of staurosporine analogs in regulating expression of endothelial nitric-oxide synthase gene
    • H. Li, U. Förstermann, Structure-activity relationship of staurosporine analogs in regulating expression of endothelial nitric-oxide synthase gene, Mol. Pharmacol. 57 (2000) 427-435.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 427-435
    • Li, H.1    Förstermann, U.2
  • 178
    • 0035050352 scopus 로고    scopus 로고
    • Decreased renal expression of nitric oxide synthase isoforms in adrenocorticotropin-induced and corticosterone-induced hypertension
    • Y.K. Lou, C. Wen, M. Li, D.J. Adams, M.X. Wang, F. Yang, B.J. Morris, J.A. Whitworth, Decreased renal expression of nitric oxide synthase isoforms in adrenocorticotropin-induced and corticosterone-induced hypertension, Hypertension 37 (2001) 1164-1170.
    • (2001) Hypertension , vol.37 , pp. 1164-1170
    • Lou, Y.K.1    Wen, C.2    Li, M.3    Adams, D.J.4    Wang, M.X.5    Yang, F.6    Morris, B.J.7    Whitworth, J.A.8
  • 179
    • 0032736528 scopus 로고    scopus 로고
    • Increased nitric oxide synthase-3 expression in kidneys of deoxycorticosterone acetate-salt hypertensive rats
    • G.H. Allcock, M. Hukkanen, J.M. Polak, J.S. Pollock, D.M. Pollock, Increased nitric oxide synthase-3 expression in kidneys of deoxycorticosterone acetate-salt hypertensive rats, J. Am. Soc. Nephrol. 10 (1999) 2283-2289.
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 2283-2289
    • Allcock, G.H.1    Hukkanen, M.2    Polak, J.M.3    Pollock, J.S.4    Pollock, D.M.5
  • 180
    • 0024348103 scopus 로고
    • Ciclosporin A inhibits endothelium-dependent vasodilatation and vascular prostacyclin production
    • C. Bossaller, U. Forstermann, R. Hertel, C. Olbricht, V. Reschke, E. Fleck, Ciclosporin A inhibits endothelium-dependent vasodilatation and vascular prostacyclin production, Eur. J. Pharmacol. 165 (1989) 165-169.
    • (1989) Eur. J. Pharmacol. , vol.165 , pp. 165-169
    • Bossaller, C.1    Forstermann, U.2    Hertel, R.3    Olbricht, C.4    Reschke, V.5    Fleck, E.6
  • 181
    • 0031791945 scopus 로고    scopus 로고
    • Role of nitric oxide in cyclosporine A-induced hypertension
    • G.K. Oriji, H.R. Keiser, Role of nitric oxide in cyclosporine A-induced hypertension, Hypertension 32 (1998) 849-855.
    • (1998) Hypertension , vol.32 , pp. 849-855
    • Oriji, G.K.1    Keiser, H.R.2
  • 182
    • 7344249590 scopus 로고    scopus 로고
    • Depressed renal and vascular nitric oxide synthase expression in cyclosporine-induced hypertension
    • N.D. Vaziri, Z. Ni, Y.P. Zhang, E.P. Ruzics, P. Maleki, Y. Ding, Depressed renal and vascular nitric oxide synthase expression in cyclosporine-induced hypertension, Kidney Int. 54 (1998) 482-491.
    • (1998) Kidney Int. , vol.54 , pp. 482-491
    • Vaziri, N.D.1    Ni, Z.2    Zhang, Y.P.3    Ruzics, E.P.4    Maleki, P.5    Ding, Y.6
  • 184
    • 33750687601 scopus 로고    scopus 로고
    • Regulation of endothelial NO synthase expression by cyclosporin A in bovine aortic endothelial cells
    • S. Lopez-Ongil, M. Saura, D. Rodriguez-Puyol, M. Rodriguez-Puyol, S. Lamas, Regulation of endothelial NO synthase expression by cyclosporin A in bovine aortic endothelial cells, Am. J. Physiol. 271 (1996) H1072-H1078.
    • (1996) Am. J. Physiol. , vol.271 , pp. H1072-H1078
    • Lopez-Ongil, S.1    Saura, M.2    Rodriguez-Puyol, D.3    Rodriguez-Puyol, M.4    Lamas, S.5
  • 185
    • 0034603063 scopus 로고    scopus 로고
    • Transcriptional induction of endothelial nitric oxide gene by cyclosporine A. A role for activator protein-1
    • J. Navarro-Antolin, J. Rey-Campos, S. Lamas, Transcriptional induction of endothelial nitric oxide gene by cyclosporine A. A role for activator protein-1, J. Biol. Chem. 275 (2000) 3075-3080.
    • (2000) J. Biol. Chem. , vol.275 , pp. 3075-3080
    • Navarro-Antolin, J.1    Rey-Campos, J.2    Lamas, S.3
  • 189
    • 0034068673 scopus 로고    scopus 로고
    • Exposure of endothelial cells to recombinant human erythropoietin induces nitric oxide synthase activity
    • D. Banerjee, M. Rodriguez, M. Nag, J.W. Adamson, Exposure of endothelial cells to recombinant human erythropoietin induces nitric oxide synthase activity, Kidney Int. 57 (2000) 1895-1904.
    • (2000) Kidney Int. , vol.57 , pp. 1895-1904
    • Banerjee, D.1    Rodriguez, M.2    Nag, M.3    Adamson, J.W.4
  • 190
    • 0032827167 scopus 로고    scopus 로고
    • Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein endothelial cells
    • X.C. Wu, E.J. Johns, N.T. Richards, Relationship between erythropoietin and nitric oxide in the contraction of rat renal arcuate arteries and human umbilical vein endothelial cells, Clin. Sci. Colch. 97 (1999) 413-419.
    • (1999) Clin. Sci. Colch. , vol.97 , pp. 413-419
    • Wu, X.C.1    Johns, E.J.2    Richards, N.T.3
  • 191
    • 0030069085 scopus 로고    scopus 로고
    • Recombinant human erythropoietin does not regulate the expression of endothelin-1 and constitutive nitric oxide synthase in vascular endothelial cells
    • S.L. Lopez-Ongil, M. Saura, S. Lamas, M. Rodriguez-Puyol, D. Rodriguez-Puyol, Recombinant human erythropoietin does not regulate the expression of endothelin-1 and constitutive nitric oxide synthase in vascular endothelial cells, Exp. Nephrol. 4 (1996) 37-42.
    • (1996) Exp. Nephrol. , vol.4 , pp. 37-42
    • Lopez-Ongil, S.L.1    Saura, M.2    Lamas, S.3    Rodriguez-Puyol, M.4    Rodriguez-Puyol, D.5
  • 192
    • 0028988330 scopus 로고
    • The pressor effect of recombinant human erythropoietin is not due to decreased activity of the endogenous nitric oxide system
    • D. del Castillo, L. Raij, P.J. Shultz, J.P. Tolins, The pressor effect of recombinant human erythropoietin is not due to decreased activity of the endogenous nitric oxide system, Nephrol. Dial. Transplant. 10 (1995) 505-508.
    • (1995) Nephrol. Dial. Transplant. , vol.10 , pp. 505-508
    • Del Castillo, D.1    Raij, L.2    Shultz, P.J.3    Tolins, J.P.4
  • 194
    • 0031840214 scopus 로고    scopus 로고
    • Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats
    • N.D. Vaziri, Z. Ni, F. Oveisi, Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats, Hypertension 31 (1998) 1248-1254.
    • (1998) Hypertension , vol.31 , pp. 1248-1254
    • Vaziri, N.D.1    Ni, Z.2    Oveisi, F.3
  • 195
    • 0032102780 scopus 로고    scopus 로고
    • Selective dysregulation of nitric oxide synthase type 3 in cardiac myocytes but not coronary microvascular endothelial cells of spontaneously hypertensive rat
    • U. Bayraktutan, Z.K. Yang, A.M. Shah, Selective dysregulation of nitric oxide synthase type 3 in cardiac myocytes but not coronary microvascular endothelial cells of spontaneously hypertensive rat, Cardiovasc. Res. 38 (1998) 719-726.
    • (1998) Cardiovasc. Res. , vol.38 , pp. 719-726
    • Bayraktutan, U.1    Yang, Z.K.2    Shah, A.M.3
  • 197
    • 0032029120 scopus 로고    scopus 로고
    • Vasodilator dysfunction in aged spontaneously hypertensive rats: Changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production
    • J. Bauersachs, A. Bouloumie, A. Mulsch, G. Wiemer, I. Fleming, R. Busse, Vasodilator dysfunction in aged spontaneously hypertensive rats: Changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production, Cardiovasc. Res. 37 (1998) 772-779.
    • (1998) Cardiovasc. Res. , vol.37 , pp. 772-779
    • Bauersachs, J.1    Bouloumie, A.2    Mulsch, A.3    Wiemer, G.4    Fleming, I.5    Busse, R.6
  • 198
    • 0034871456 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase protein is reduced in the renal medulla of two-kidney, one-clip hypertensive rats
    • A. Wickman, I.J. Andersson, J. Jia, L. Hedin, G. Bergstrom, Endothelial nitric oxide synthase protein is reduced in the renal medulla of two-kidney, one-clip hypertensive rats, J. Hypertens. 19 (2001) 1665-1673.
    • (2001) J. Hypertens. , vol.19 , pp. 1665-1673
    • Wickman, A.1    Andersson, I.J.2    Jia, J.3    Hedin, L.4    Bergstrom, G.5
  • 199
    • 0035071093 scopus 로고    scopus 로고
    • Celiprolol stimulates endothelial nitric oxide synthase expression and improves myocardial remodeling in deoxycorticosterone acetate-salt hypertensive rats
    • N. Kobayashi, Y. Mori, S. Nakano, Y. Tsubokou, H. Shirataki, H. Matsuoka, Celiprolol stimulates endothelial nitric oxide synthase expression and improves myocardial remodeling in deoxycorticosterone acetate-salt hypertensive rats, J. Hypertens. 19 (2001) 795-801.
    • (2001) J. Hypertens. , vol.19 , pp. 795-801
    • Kobayashi, N.1    Mori, Y.2    Nakano, S.3    Tsubokou, Y.4    Shirataki, H.5    Matsuoka, H.6
  • 200
    • 0032743579 scopus 로고    scopus 로고
    • Nitric oxide synthase expression in the course of lead-induced hypertension
    • N.D. Vaziri, Y. Ding, Z. Ni, Nitric oxide synthase expression in the course of lead-induced hypertension, Hypertension 34 (1999) 558-562.
    • (1999) Hypertension , vol.34 , pp. 558-562
    • Vaziri, N.D.1    Ding, Y.2    Ni, Z.3
  • 201
    • 0032787942 scopus 로고    scopus 로고
    • Effects of amlodipine on nitric oxide synthase mRNA expression and coronary microcirculation in prolonged nitric oxide blockade-induced hypertensive rats
    • N. Kobayashi, H. Yanaka, A. Tojo, K. Kobayashi, H. Matsuoka, Effects of amlodipine on nitric oxide synthase mRNA expression and coronary microcirculation in prolonged nitric oxide blockade-induced hypertensive rats, J. Cardiovasc. Pharmacol. 34 (1999) 173-181.
    • (1999) J. Cardiovasc. Pharmacol. , vol.34 , pp. 173-181
    • Kobayashi, N.1    Yanaka, H.2    Tojo, A.3    Kobayashi, K.4    Matsuoka, H.5


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