Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury

Circulation Research

Volumn 80, Issue 6, 1997, Pages 894-901

  Ma, Xin L ^a,c   Lopez, Bernard L ^a   Liu, Gao Lin ^a   Christopher, Theodore A ^a   Gao, Feng ^a   Guo, Yaping ^a   Feuerstein, Giora Z ^b   Ruffolo Jr , Robert R ^b   Barone, Frank C ^b   Yue, Tian Li ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

atherosclerosis; free radical; glutathione; tissue injury

Indexed keywords

ANTIOXIDANT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARVEDILOL; GLUTATHIONE; NITRIC OXIDE; PEROXYNITRITE; PROPRANOLOL;

ANIMAL TISSUE; ARTERY INJURY; ARTICLE; CONTROLLED STUDY; HYPERCHOLESTEROLEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; VASODILATATION;

EID: 0030918339     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.80.6.894     Document Type: Article

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