Cellular antioxidant effects of atorvastatin in vitro and in vivo

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 2, 2002, Pages 300-305

  Wassmann, Sven ^a   Laufs, Ulrich ^a   Müller, Kirsten ^a   Konkol, Christian ^a   Ahlbory, Katja ^a   Bäurmer, Anselm T ^a   Linz, Wolfgang ^a   Böhm, Michael ^a   Nickenig, Georg ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

NAD(P)H oxidase; Reactive oxygen species; Spontaneously hypertensive rats; Statins; Vascular smooth muscle cells

Indexed keywords

25 HYDROXYCHOLESTEROL; ANGIOTENSIN; ATORVASTATIN; CATALASE; EPIDERMAL GROWTH FACTOR; GENE PRODUCT; GLUTATHIONE PEROXIDASE; GUANOSINE TRIPHOSPHATASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOENZYME; LUCIGENIN; MESSENGER RNA; MEVALONIC ACID; PROTEIN NOX1; PROTEIN P22PHOX; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD VESSEL INJURY; CELL MEMBRANE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOSOL; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; GENE EXPRESSION; GENE TRANSLOCATION; IN VITRO STUDY; IN VIVO STUDY; LASER MICROSCOPY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; CATALASE; CATTLE; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERTENSION; MUSCLE, SMOOTH, VASCULAR; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; PYRROLES; RATS; RATS, INBRED SHR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; UP-REGULATION;

EID: 0036162113     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq0202.104081     Document Type: Article

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