c-Jun N-Terminal kinase 2 deficiency protects against hypercholesterolemia- induced endothelial dysfunction and oxidative stress

Circulation

Volumn 118, Issue 20, 2008, Pages 2073-2080

  Osto, Elena ^a,b   Matter, Christian M ^a,b   Kouroedov, Alexei ^a,b   Malinski, Tadeusz ^c   Bachschmid, Markus ^d   Camici, Giovanni G ^a   Kilic, Ulkan ^a   Stallmach, Thomas ^a   Boren, Jan ^e   Iliceto, Sabino ^f   Lüscher, Thomas F ^a,b   Cosentino, Francesco ^a,b,g  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c OHIO UNIVERSITY   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

^f UNIVERSITY OF PADOVA   (Italy)

^g SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Atherosclerosis; Endothelium; JNK kinase; Nitric oxide; Reactive oxygen species

Indexed keywords

3 NITROTYROSINE; ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE 9; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SCAVENGER; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GENE DELETION; HYPERCHOLESTEROLEMIA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PEROXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

ACETYLCHOLINE; ANIMALS; AORTA; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HYPERCHOLESTEROLEMIA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPIDS; MALE; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 9; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; VASODILATION; VASODILATOR AGENTS;

EID: 57149134387     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.765032     Document Type: Article

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