Protein kinase C β and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

Science

Volumn 315, Issue 5812, 2007, Pages 659-663

  Pinton, Paolo ^a   Rimessi, Alessandro ^a   Marchi, Saverio ^a   Orsini, Francesca ^b,c   Migliaccio, Enrica ^b,c   Giorgio, Marco ^b,c   Contursi, Cristina ^d   Minucci, Saverio ^d   Mantovani, Fiamma ^e,f   Wieckowski, Mariusz R ^a,g   Del Sal, Giannino ^e,f   Pelicci, Pier Giuseppe ^b,c,h   Rizzuto, Rosario ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d MIKAMAI Srl   (Italy)

^e Laboratorio Nazionale CIB   (Italy)

^f UNIVERSITY OF TRIESTE   (Italy)

^g NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^h UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYTOCHROME C; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; OKADAIC ACID; PROTEIN KINASE C BETA; PROTEIN P66; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ENZYME ACTIVITY; MITOCHONDRION;

AGING; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIFESPAN; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM SIGNALING; CELL AGING; CELL SURVIVAL; CELLS, CULTURED; CYCLOSPORINE; HYDROGEN PEROXIDE; MICE; MITOCHONDRIA; MUTATION; OXIDATIVE STRESS; PEPTIDYLPROLYL ISOMERASE; PERMEABILITY; PHOSPHORYLATION; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 33846817351     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1135380     Document Type: Article

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