Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease

Journal of Cardiovascular Pharmacology

Volumn 35, Issue 2, 2000, Pages 173-178

  Maier, Willibald ^a   Cosentino, Francesco ^b,c   Lütolf, Roland B ^a   Fleisch, Martin ^a   Seiler, Christian ^a   Hess, Otto M ^a   Meier, Bernhard ^a   Lüscher, Thomas F ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c IRCCS NEUROMED   (Italy)

Author keywords

Acetylcholine; Coronary artery disease; Coronary vasomotion; Endothelial dysfunction; Nitric oxide synthase (NOS); Tetrahydrobiopterin

Indexed keywords

ACETYLCHOLINE; GLYCERYL TRINITRATE; TETRAHYDROBIOPTERIN;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTERY ENDOTHELIUM; ARTICLE; CLINICAL ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; DRUG EFFECT; DRUG SCREENING; FEMALE; HUMAN; INTRACORONARY INFUSION; MALE; PRIORITY JOURNAL; VASOCONSTRICTION; VASODILATATION;

ACETYLCHOLINE; ADENOSINE; AGED; ANGIOGRAPHY; ANTIOXIDANTS; BIOPTERIN; CORONARY DISEASE; CORONARY VESSELS; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; NITROGLYCERIN; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 0033967254     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200002000-00001     Document Type: Article

References (3)

1. Anggard E. Nitric oxide: mediator, murderer, and medicine. Lancet 1994;343:1199-206.
2. 2+/calmodulin-dependent nitric oxide synthase from porcine cerebellum: cofactor-role of tetrahydrobiopterin. FEBS Lett 1990;277:215-9.
3. Wever RM, Lüscher TF, Cosentino F, Rabelink TJ. Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation 1998;97:108-12.