Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing

Cellular and Molecular Life Sciences

Volumn 66, Issue 22, 2009, Pages 3539-3554

  Webb, James D ^a   Coleman, Mathew L ^a   Pugh, Christopher W ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Asparaginyl hydroxylase; FIH; HIF; Hypoxia; Oxygen sensing; PHD; Prolyl hydroxylase

Indexed keywords

2 OXOGLUTARIC ACID; AMINO ACID; COBALT CHLORIDE; DEFEROXAMINE; DIMETHYLOXALYLGLYCINE; ERYTHROPOIETIN; FG 0041; FG 2216; FG 4487; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MIMOSINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; OXYGENASE; OXYGENASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ANGIOGENESIS; BLOOD VESSEL TONE; CELL GROWTH; CELL SURVIVAL; DNA REPAIR; GENE CONTROL; GENE EXPRESSION; GLYCOLYSIS; HEART INFARCTION; HUMAN; HYDROXYLATION; HYPOXIA; MITOCHONDRION; MUTATION; NONHUMAN; OXYGEN SENSING; OXYGENATION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL HYPOXIA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; OXYGEN; OXYGEN CONSUMPTION; PROTEIN ISOFORMS; TRANSCRIPTION FACTORS;

EID: 70449527373     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0147-7     Document Type: Review

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