FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Genes and Development

Volumn 16, Issue 12, 2002, Pages 1466-1471

  Lando, David ^a   Peet, Daniel J ^a   Gorman, Jeffrey J ^b   Whelan, Dean A ^b   Whitelaw, Murray L ^a   Bruick, Richard K ^c  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b CSIRO   (Australia)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Asparaginyl hydroxylase; HIF; Hypoxia; Oxygen sensing

Indexed keywords

ASPARAGINYL HYDROXYLASE; HYPOXIA INDUCIBLE FACTOR 1; OXYGEN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ANIMALS; ANOXIA; ASPARAGINE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; GLUTATHIONE TRANSFERASE; HUMANS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IRON; KETOGLUTARIC ACIDS; MASS SPECTROMETRY; MICE; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; OXYGEN; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

MAMMALIA;

EID: 0037097861     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.991402     Document Type: Article

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