Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1α, HIF-2α, and other pathways

Journal of Biological Chemistry

Volumn 281, Issue 22, 2006, Pages 15215-15226

  Elvidge, Gareth P ^b   Glenny, Louisa ^b   Appelhoff, Rebecca J ^a   Ratcliffe, Peter J ^a   Ragoussis, Jiannis ^b   Gleadle, Jonathan M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; ENZYME KINETICS; GENES; GENETIC ENGINEERING; OXYGEN; RNA;

DIMETHYLOXALYLGLYCINE (DMOG); GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR (HIF); SIGNAL PATHWAYS;

ENZYMES;

2 OXOGLUTARIC ACID; DIMETHYLOXALYLGLYCINE; DIOXYGENASE; ENZYME INHIBITOR; FIH1 ENZYME; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OXYGEN; PHD1 ENZYME; PHD2 ENZYME; PHD3 ENZYME; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; DNA MODIFICATION; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; OXYGEN SENSING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UNINDEXED SEQUENCE;

EID: 33744954065     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511408200     Document Type: Article

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