Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

Journal of Biological Chemistry

Volumn 279, Issue 37, 2004, Pages 38458-38465

  Appelhoffl, Rebecca J ^a   Tian, Ya Min ^a   Raval, Raju R ^a   Turley, Helen ^b   Harris, Adrian L ^c   Pugh, Christopher W ^a   Ratcliffe, Peter J ^a   Gleadle, Jonathan M ^a  

^a Henry Wellcome Bldg of Genomic Med ^*  (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; HYDROXYLATION; OXYGEN; RNA;

DIFFERENTIAL FUNCTION; HOMEOSTASIS; HYPOXIA-INDUCIBLE FACTOR;

ENZYMES;

ESTROGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; ISOENZYME; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE DOMAIN 1; PROLYL HYDROXYLASE DOMAIN 2; PROLYL HYDROXYLASE DOMAIN 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL HYPOXIA; CELL STRAIN MCF 7; CONTROLLED STUDY; GENETIC TRANSFECTION; HELA CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; HYDROXYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; REOXYGENATION; REPORTER GENE; RIBONUCLEASE PROTECTION ASSAY; TRANSCRIPTION REGULATION;

ANIMALS; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CATALYSIS; CELL LINE; CELL LINE, TUMOR; DIOXYGENASES; DNA-BINDING PROTEINS; ESTRADIOL; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMEDIATE-EARLY PROTEINS; IMMUNOBLOTTING; KINETICS; MICE; MICE, INBRED BALB C; NUCLEAR PROTEINS; OXYGEN; PLASMIDS; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN ISOFORMS; RECOMBINANT FUSION PROTEINS; RIBONUCLEASES; RNA; RNA, MESSENGER; RNA, SMALL INTERFERING; SENSITIVITY AND SPECIFICITY; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

MINK CELL FOCUS-FORMING VIRUS;

EID: 4644318828     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406026200     Document Type: Article

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