C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Cell

Volumn 107, Issue 1, 2001, Pages 43-54

  Epstein, Andrew C R ^a   Gleadle, Jonathan M ^a   McNeill, Luke A ^b   Hewitson, Kirsty S ^b   O'Rourke, John ^a   Mole, David R ^a   Mukherji, Mridul ^b   Metzen, Eric ^a   Wilson, Michael I ^a   Dhanda, Anu ^b   Tian, Ya Min ^a   Masson, Norma ^a   Hamilton, Donald L ^a   Jaakkola, Panu ^a   Barstead, Robert ^c   Hodgkin, Jonathan ^d   Maxwell, Patrick H ^a   Pugh, Christopher W ^a   Schofield, Christopher J ^b   Ratcliffe, Peter J ^a  

^a The Henry Wellcome Building of Genomic Medicine ^*  (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ION; IRON; ISOPROTEIN; OXYGEN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN; PROTEIN EGL 9; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CATALYSIS; CELL HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROXYLATION; IRON CHELATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SENSOR;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 17944375360     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00507-4     Document Type: Article

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