The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

Journal of Biological Chemistry

Volumn 281, Issue 39, 2006, Pages 28712-28720

  Koivunen, Peppi ^a   Hirsilä, Maija ^a   Kivirikko, Kari I ^a   Myllyharju, Johanna ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

19-RESIDUE PEPTIDE; C-TERMINAL SITES; HYPOXIA-INDUCIBLE FACTOR PROLYL 4-HYDROXYLASES (HIF-P4H); N SITE PEPTIDES;

AMINO ACIDS; BIOSENSORS; GENETIC ENGINEERING; HYDROXYLATION; MUTAGENESIS; OXYGEN; SUBSTRATES;

PROTEINS;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; ISOENZYME; PEPTIDE DERIVATIVE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE DERIVATIVE; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HIF 3ALPHA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYDROXYLATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOXIA-INDUCIBLE FACTOR 1; INSECTS; KINETICS; MOLECULAR SEQUENCE DATA; MUTATION; OXYGEN; PEPTIDES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 33749410367     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604628200     Document Type: Article

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