Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

Nature Genetics

Volumn 35, Issue 4, 2003, Pages 331-340

  Scortegagna, Marzia ^a   Ding, Kan ^a   Oktay, Yavuz ^a   Gaur, Arti ^a   Thurmond, Frederick ^a   Yan, Liang Jun ^a   Marck, Brett T ^b   Matsumoto, Alvin M ^b   Shelton, John M ^a,c   Richardson, James A ^a,c   Bennet, Michael J ^a,d   Garcia, Joseph A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d CHILDREN S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL PAS DOMAIN PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 2ALPHA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; BONE MARROW DISEASE; CHEMICAL ANALYSIS; CITRIC ACID CYCLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FATTY ACID OXIDATION; FATTY LIVER; GENE EXPRESSION; GENETIC TRANSFECTION; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HOMEOSTASIS; HYPOGLYCEMIA; LACTIC ACIDOSIS; METABOLIC DISORDER; MOUSE; MULTIPLE ORGAN FAILURE; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RETINOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; ULTRASTRUCTURE;

ABNORMALITIES, MULTIPLE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION REGULATION; HEART; HOMEOSTASIS; HOMOZYGOTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR MIMICRY; MUSCLE, SKELETAL; NEOPLASM PROTEINS; OXIDATIVE STRESS; PEROXIDASES; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; SURVIVAL RATE; TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA;

EID: 0344826529     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1266     Document Type: Article

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