Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (HIF) in regulating HIF transcriptional target genes

Journal of Biological Chemistry

Volumn 279, Issue 41, 2004, Pages 42719-42725

  Stolze, Ineke P ^a   Tian, Ya Min ^a   Appelhoff, Rebecca J ^a   Turley, Helen ^b   Wykoff, Charles C ^c   Gleadle, Jonathan M ^a   Ratcliffe, Peter J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME KINETICS; GENES; GENETIC ENGINEERING; OXYGEN;

GENE EXPRESSIONS; HYPOXIA-INDUCIBLE FACTORS (HIF); TARGET GENES; TRANSCRIPTION;

ENZYME INHIBITION;

ASPARAGINYL HYDROXYLASE; DOXYCYCLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL HYPOXIA; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

ANIMALS; ANOXIA; CELL LINE; COS CELLS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXYCYCLINE; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMEDIATE-EARLY PROTEINS; IMMUNOBLOTTING; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; NUCLEAR PROTEINS; OXYGEN; PLASMIDS; PROCOLLAGEN-PROLINE DIOXYGENASE; REPRESSOR PROTEINS; RNA; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA; MAMMALIA;

EID: 5644240828     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406713200     Document Type: Article

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