HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Cancer Cell

Volumn 8, Issue 2, 2005, Pages 143-153

  Isaacs, Jennifer S ^a,e   Yun, Jin Jung ^b   Mole, David R ^c   Lee, Sunmin ^a   Torres Cabala, Carlos ^a   Chung, Yuen Li ^d   Merino, Maria ^a   Trepel, Jane ^a   Zbar, Berton ^a   Toro, Jorge ^a   Ratcliffe, Peter J ^c   Linehan, W Marston ^a   Neckers, Len ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Pusan National University   (South Korea)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROPROPIONIC ACID; CYCLOHEXIMIDE; ENZYME INHIBITOR; FUMARATE HYDRATASE; FUMARIC ACID; HYPOXIA INDUCIBLE FACTOR 1; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SMALL INTERFERING RNA;

ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GENE LOSS; HUMAN; HUMAN TISSUE; HYDROXYLATION; KIDNEY CANCER; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; UPREGULATION;

EID: 23644448721     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2005.06.017     Document Type: Article

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