HIF-1α-prolyl hydroxylase: Molecular target of nitric oxide in the hypoxic signal transduction pathway

Biochemical and Biophysical Research Communications

Volumn 295, Issue 3, 2002, Pages 657-662

  Wang, Feng ^a,c   Sekine, Hiroki ^a   Kikuchi, Yasuo ^a   Takasaki, Chikahisa ^a   Miura, Chisa ^a   Heiwa, Okuda ^b   Shuin, Taro ^b   Fujii Kuriyama, Yoshiaki ^a,d   Sogawa, Kazuhiro ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b KOCHI MEDICAL SCHOOL   (Japan)

^c UCLA MEDICAL CENTER   (United States)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

HIF 1; Hypoxia; Nitric oxide; Oxygen; Proline hydroxylation; pVHL

Indexed keywords

2 OXOGLUTARIC ACID; BINDING PROTEIN; CELL EXTRACT; COBALT CHLORIDE; DEFEROXAMINE; FERROUS ION; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1ALPHA PROLYL HYDROXYLASE; NITRIC OXIDE; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN; ALPHA-KETOGLUTARIC ACID; COBALT; COMPLEMENTARY DNA; DNA FRAGMENT; HIF1A PROTEIN, HUMAN; LUCIFERASE; SEPHAROSE; SODIUM CHLORIDE; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; CELL HYPOXIA; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; HYDROXYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANOXIA; CHEMISTRY; DOSE RESPONSE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TIME; WESTERN BLOTTING;

ANOXIA; BLOTTING, WESTERN; CELL LINE; COBALT; DNA FRAGMENTATION; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETOGLUTARIC ACIDS; LUCIFERASES; NITRIC OXIDE; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEPHAROSE; SIGNAL TRANSDUCTION; SODIUM CHLORIDE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0035984138     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00729-5     Document Type: Article

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