Targeted replacement of hypoxia-inducible factor-1α by a hypoxia-inducible factor-2α knock-in allele promotes tumor growth

Cancer Research

Volumn 65, Issue 6, 2005, Pages 2277-2286

  Covello, Kelly L ^a   Simon, M Celeste ^a,b   Keith, Brian ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN;

ALLELE; ARTICLE; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE LOCUS; GENE OVEREXPRESSION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TERATOMA; TRANSCRIPTION REGULATION; TUMOR GROWTH;

ALLELES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELL TRANSFORMATION, NEOPLASTIC; EMBRYO; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; STEM CELLS; TERATOMA; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 16844386959     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3246     Document Type: Article

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