Mechanism of regulation of the hypoxia-inducible factor-la by the von Hippel-Lindau tumor suppressor protein

EMBO Journal

Volumn 19, Issue 16, 2000, Pages 4298-4309

  Tanimoto, Keiji ^a   Makino, Yuichi ^a   Pereira, Teresa ^a   Poellinger, Lorenz ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Hypoxia inducible factor 1 ; Transcription; Tumor suppression; Ubiquitylation; Von Hippel Lindau protein

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL CELL; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; VON HIPPEL LINDAU DISEASE;

AMINO ACID SEQUENCE; ANIMALS; ANOXIA; BINDING SITES; CELL LINE; COS CELLS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GREEN FLUORESCENT PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; LIGASES; LUMINESCENT PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTATION; NUCLEAR PROTEINS; OXYGEN; PLASMIDS; PRECIPITIN TESTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

ANIMALIA;

EID: 0034663894     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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