-
1
-
-
0022640843
-
Two types of murine helper T cell clone, I: definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., and Coffman R.L. Two types of murine helper T cell clone, I: definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136 (1986) 2348-2357
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
2
-
-
33947720523
-
Development in motion: helper T cells at work
-
Reiner S.L. Development in motion: helper T cells at work. Cell 129 (2007) 33-36
-
(2007)
Cell
, vol.129
, pp. 33-36
-
-
Reiner, S.L.1
-
3
-
-
33846966636
-
A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 13 (2007) 139-145
-
(2007)
Nat Med
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
4
-
-
36249024247
-
Regulatory T cells: a brief history and perspective
-
Sakaguchi S., Wing K., and Miyara M. Regulatory T cells: a brief history and perspective. Eur J Immunol 37 suppl 1 (2007) S116-S123
-
(2007)
Eur J Immunol
, vol.37
, Issue.SUPPL. 1
-
-
Sakaguchi, S.1
Wing, K.2
Miyara, M.3
-
6
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441 (2006) 235-238
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
-
7
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan P.R., Harrington L.E., O'Quinn D.B., Helms W.S., Bullard D.C., Elson C.O., et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441 (2006) 231-234
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
-
8
-
-
33745818935
-
TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells
-
Veldhoen M., and Stockinger B. TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells. Trends Immunol 27 (2006) 358-361
-
(2006)
Trends Immunol
, vol.27
, pp. 358-361
-
-
Veldhoen, M.1
Stockinger, B.2
-
9
-
-
33646012294
-
T helper cell differentiation: regulation by cis elements and epigenetics
-
Lee G.R., Kim S.T., Spilianakis C.G., Fields P.E., and Flavell R.A. T helper cell differentiation: regulation by cis elements and epigenetics. Immunity 24 (2006) 369-379
-
(2006)
Immunity
, vol.24
, pp. 369-379
-
-
Lee, G.R.1
Kim, S.T.2
Spilianakis, C.G.3
Fields, P.E.4
Flavell, R.A.5
-
11
-
-
0036885067
-
Decision making in the immune system: the lineage decisions of helper T cells
-
Murphy K.M., and Reiner S.L. Decision making in the immune system: the lineage decisions of helper T cells. Nat Rev Immunol 2 (2002) 933-944
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
12
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo S.J., Kim S.T., Costa G.L., Zhang X., Fathman C.G., and Glimcher L.H. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100 (2000) 655-669
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
13
-
-
0242410712
-
Control of effector CD8+ T cell function by the transcription factor eomesodermin
-
Pearce E.L., Mullen A.C., Martins G.A., Krawczyk C.M., Hutchins A.S., Zediak V.P., et al. Control of effector CD8+ T cell function by the transcription factor eomesodermin. Science 302 (2003) 1041-1043
-
(2003)
Science
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
Mullen, A.C.2
Martins, G.A.3
Krawczyk, C.M.4
Hutchins, A.S.5
Zediak, V.P.6
-
14
-
-
33846489173
-
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
-
Djuretic I.M., Levanon D., Negreanu V., Groner Y., Rao A., and Ansel K.M. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat Immunol 8 (2007) 145-153
-
(2007)
Nat Immunol
, vol.8
, pp. 145-153
-
-
Djuretic, I.M.1
Levanon, D.2
Negreanu, V.3
Groner, Y.4
Rao, A.5
Ansel, K.M.6
-
15
-
-
0036301997
-
Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
-
Mullen A.C., Hutchins A.S., High F.A., Lee H.W., Sykes K.J., Chodosh L.A., et al. Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat Immunol 3 (2002) 652-658
-
(2002)
Nat Immunol
, vol.3
, pp. 652-658
-
-
Mullen, A.C.1
Hutchins, A.S.2
High, F.A.3
Lee, H.W.4
Sykes, K.J.5
Chodosh, L.A.6
-
16
-
-
37549032110
-
T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain
-
Lewis M.D., Miller S.A., Miazgowicz M.M., Beima K.M., and Weinmann A.S. T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain. Mol Cell Biol 27 (2007) 8510-8521
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8510-8521
-
-
Lewis, M.D.1
Miller, S.A.2
Miazgowicz, M.M.3
Beima, K.M.4
Weinmann, A.S.5
-
17
-
-
27144526101
-
Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression
-
Martins G.A., Hutchins A.S., and Reiner S.L. Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression. J Immunol 175 (2005) 5981-5985
-
(2005)
J Immunol
, vol.175
, pp. 5981-5985
-
-
Martins, G.A.1
Hutchins, A.S.2
Reiner, S.L.3
-
18
-
-
0035997908
-
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
-
Afkarian M., Sedy J.R., Yang J., Jacobson N.G., Cereb N., Yang S.Y., et al. T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells. Nat Immunol 3 (2002) 549-557
-
(2002)
Nat Immunol
, vol.3
, pp. 549-557
-
-
Afkarian, M.1
Sedy, J.R.2
Yang, J.3
Jacobson, N.G.4
Cereb, N.5
Yang, S.Y.6
-
19
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
Mullen A.C., High F.A., Hutchins A.S., Lee H.W., Villarino A.V., Livingston D.M., et al. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science 292 (2001) 1907-1910
-
(2001)
Science
, vol.292
, pp. 1907-1910
-
-
Mullen, A.C.1
High, F.A.2
Hutchins, A.S.3
Lee, H.W.4
Villarino, A.V.5
Livingston, D.M.6
-
20
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui T., Preiss J.C., Kanno Y., Yao Z.J., Bream J.H., O'Shea J.J., et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med 203 (2006) 755-766
-
(2006)
J Exp Med
, vol.203
, pp. 755-766
-
-
Usui, T.1
Preiss, J.C.2
Kanno, Y.3
Yao, Z.J.4
Bream, J.H.5
O'Shea, J.J.6
-
21
-
-
0037059462
-
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
-
Szabo S.J., Sullivan B.M., Stemmann C., Satoskar A.R., Sleckman B.P., and Glimcher L.H. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295 (2002) 338-342
-
(2002)
Science
, vol.295
, pp. 338-342
-
-
Szabo, S.J.1
Sullivan, B.M.2
Stemmann, C.3
Satoskar, A.R.4
Sleckman, B.P.5
Glimcher, L.H.6
-
22
-
-
0037059509
-
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
-
Finotto S., Neurath M.F., Glickman J.N., Qin S., Lehr H.A., Green F.H., et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295 (2002) 336-338
-
(2002)
Science
, vol.295
, pp. 336-338
-
-
Finotto, S.1
Neurath, M.F.2
Glickman, J.N.3
Qin, S.4
Lehr, H.A.5
Green, F.H.6
-
23
-
-
23844473010
-
Asthmatic changes in mice lacking T-bet are mediated by IL-13
-
Finotto S., Hausding M., Doganci A., Maxeiner J.H., Lehr H.A., Luft C., et al. Asthmatic changes in mice lacking T-bet are mediated by IL-13. Int Immunol 17 (2005) 993-1007
-
(2005)
Int Immunol
, vol.17
, pp. 993-1007
-
-
Finotto, S.1
Hausding, M.2
Doganci, A.3
Maxeiner, J.H.4
Lehr, H.A.5
Luft, C.6
-
24
-
-
30344438533
-
T-bet polymorphisms are associated with asthma and airway hyperresponsiveness
-
Raby B.A., Hwang E.S., Van Steen K., Tantisira K., Peng S., Litonjua A., et al. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med 173 (2006) 64-70
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 64-70
-
-
Raby, B.A.1
Hwang, E.S.2
Van Steen, K.3
Tantisira, K.4
Peng, S.5
Litonjua, A.6
-
25
-
-
38449083851
-
Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis
-
Fortin A., Abel L., Casanova J.L., and Gros P. Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis. Annu Rev Genomics Hum Genet 8 (2007) 163-192
-
(2007)
Annu Rev Genomics Hum Genet
, vol.8
, pp. 163-192
-
-
Fortin, A.1
Abel, L.2
Casanova, J.L.3
Gros, P.4
-
26
-
-
33845897463
-
Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity
-
Minegishi Y., Saito M., Morio T., Watanabe K., Agematsu K., Tsuchiya S., et al. Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity. Immunity 25 (2006) 745-755
-
(2006)
Immunity
, vol.25
, pp. 745-755
-
-
Minegishi, Y.1
Saito, M.2
Morio, T.3
Watanabe, K.4
Agematsu, K.5
Tsuchiya, S.6
-
27
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel K.M., Djuretic I., Tanasa B., and Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 24 (2006) 607-656
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
28
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W., and Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89 (1997) 587-596
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
29
-
-
0030764961
-
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
-
Zhang D.H., Cohn L., Ray P., Bottomly K., and Ray A. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem 272 (1997) 21597-21603
-
(1997)
J Biol Chem
, vol.272
, pp. 21597-21603
-
-
Zhang, D.H.1
Cohn, L.2
Ray, P.3
Bottomly, K.4
Ray, A.5
-
30
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang W., Lohning M., Gao Z., Assenmacher M., Ranganath S., Radbruch A., et al. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 12 (2000) 27-37
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
Lohning, M.2
Gao, Z.3
Assenmacher, M.4
Ranganath, S.5
Radbruch, A.6
-
31
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
-
Ouyang W., Ranganath S.H., Weindel K., Bhattacharya D., Murphy T.L., Sha W.C., et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9 (1998) 745-755
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
Ranganath, S.H.2
Weindel, K.3
Bhattacharya, D.4
Murphy, T.L.5
Sha, W.C.6
-
32
-
-
0033212806
-
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3
-
Zhang D.H., Yang L., Cohn L., Parkyn L., Homer R., Ray P., et al. Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3. Immunity 11 (1999) 473-482
-
(1999)
Immunity
, vol.11
, pp. 473-482
-
-
Zhang, D.H.1
Yang, L.2
Cohn, L.3
Parkyn, L.4
Homer, R.5
Ray, P.6
-
33
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses
-
Zhu J., Min B., Hu-Li J., Watson C.J., Grinberg A., Wang Q., et al. Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol 5 (2004) 1157-1165
-
(2004)
Nat Immunol
, vol.5
, pp. 1157-1165
-
-
Zhu, J.1
Min, B.2
Hu-Li, J.3
Watson, C.J.4
Grinberg, A.5
Wang, Q.6
-
34
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai S.Y., Truitt M.L., and Ho I.C. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A 101 (2004) 1993-1998
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
35
-
-
31144460961
-
GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors
-
Zhu J., Yamane H., Cote-Sierra J., Guo L., and Paul W.E. GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors. Cell Res 16 (2006) 3-10
-
(2006)
Cell Res
, vol.16
, pp. 3-10
-
-
Zhu, J.1
Yamane, H.2
Cote-Sierra, J.3
Guo, L.4
Paul, W.E.5
-
36
-
-
0033049690
-
Gene expression of the GATA-3 transcription factor is increased in atopic asthma
-
Nakamura Y., Ghaffar O., Olivenstein R., Taha R.A., Soussi-Gounni A., Zhang D.H., et al. Gene expression of the GATA-3 transcription factor is increased in atopic asthma. J Allergy Clin Immunol 103 (1999) 215-222
-
(1999)
J Allergy Clin Immunol
, vol.103
, pp. 215-222
-
-
Nakamura, Y.1
Ghaffar, O.2
Olivenstein, R.3
Taha, R.A.4
Soussi-Gounni, A.5
Zhang, D.H.6
-
37
-
-
0035806279
-
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression
-
Finotto S., De Sanctis G.T., Lehr H.A., Herz U., Buerke M., Schipp M., et al. Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression. J Exp Med 193 (2001) 1247-1260
-
(2001)
J Exp Med
, vol.193
, pp. 1247-1260
-
-
Finotto, S.1
De Sanctis, G.T.2
Lehr, H.A.3
Herz, U.4
Buerke, M.5
Schipp, M.6
-
38
-
-
37549010258
-
Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness
-
Lee C.C., Huang H.Y., and Chiang B.L. Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness. Mol Ther 16 (2008) 60-65
-
(2008)
Mol Ther
, vol.16
, pp. 60-65
-
-
Lee, C.C.1
Huang, H.Y.2
Chiang, B.L.3
-
39
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho I.C., Hodge M.R., Rooney J.W., and Glimcher L.H. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85 (1996) 973-983
-
(1996)
Cell
, vol.85
, pp. 973-983
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
40
-
-
0033152267
-
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
-
Kim J.I., Ho I.C., Grusby M.J., and Glimcher L.H. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity 10 (1999) 745-751
-
(1999)
Immunity
, vol.10
, pp. 745-751
-
-
Kim, J.I.1
Ho, I.C.2
Grusby, M.J.3
Glimcher, L.H.4
-
41
-
-
0030474682
-
NF-AT-Driven interleukin-4 transcription potentiated by NIP45
-
Hodge M.R., Chun H.J., Rengarajan J., Alt A., Lieberson R., and Glimcher L.H. NF-AT-Driven interleukin-4 transcription potentiated by NIP45. Science 274 (1996) 1903-1905
-
(1996)
Science
, vol.274
, pp. 1903-1905
-
-
Hodge, M.R.1
Chun, H.J.2
Rengarajan, J.3
Alt, A.4
Lieberson, R.5
Glimcher, L.H.6
-
42
-
-
27644433355
-
Role of regulatory T cells in human diseases
-
quiz 60
-
Chatila T.A. Role of regulatory T cells in human diseases. J Allergy Clin Immunol 116 (2005) 949-959 quiz 60
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 949-959
-
-
Chatila, T.A.1
-
43
-
-
34547138154
-
Role of regulatory T cells and FOXP3 in human diseases
-
quiz 36-7
-
Bacchetta R., Gambineri E., and Roncarolo M.G. Role of regulatory T cells and FOXP3 in human diseases. J Allergy Clin Immunol 120 (2007) 227-235 quiz 36-7
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 227-235
-
-
Bacchetta, R.1
Gambineri, E.2
Roncarolo, M.G.3
-
44
-
-
34247277666
-
Foxp3 in control of the regulatory T cell lineage
-
Zheng Y., and Rudensky A.Y. Foxp3 in control of the regulatory T cell lineage. Nat Immunol 8 (2007) 457-462
-
(2007)
Nat Immunol
, vol.8
, pp. 457-462
-
-
Zheng, Y.1
Rudensky, A.Y.2
-
45
-
-
27544446622
-
Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
-
D'Cruz L.M., and Klein L. Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol 6 (2005) 1152-1159
-
(2005)
Nat Immunol
, vol.6
, pp. 1152-1159
-
-
D'Cruz, L.M.1
Klein, L.2
-
46
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot J.D., Rasmussen J.P., Gavin M.A., and Rudensky A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 6 (2005) 1142-1151
-
(2005)
Nat Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
47
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
-
Marie J.C., Letterio J.J., Gavin M., and Rudensky A.Y. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 201 (2005) 1061-1067
-
(2005)
J Exp Med
, vol.201
, pp. 1061-1067
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
48
-
-
34948875308
-
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells
-
quiz 51-2
-
Torgerson T.R., and Ochs H.D. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J Allergy Clin Immunol 120 (2007) 744-750 quiz 51-2
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 744-750
-
-
Torgerson, T.R.1
Ochs, H.D.2
-
49
-
-
33846805925
-
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes
-
Caudy A.A., Reddy S.T., Chatila T., Atkinson J.P., and Verbsky J.W. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes. J Allergy Clin Immunol 119 (2007) 482-487
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 482-487
-
-
Caudy, A.A.1
Reddy, S.T.2
Chatila, T.3
Atkinson, J.P.4
Verbsky, J.W.5
-
50
-
-
33747775187
-
Cutting edge: Decreased accumulation and regulatory function of CD4+ CD25(high) T cells in human STAT5b deficiency
-
Cohen A.C., Nadeau K.C., Tu W., Hwa V., Dionis K., Bezrodnik L., et al. Cutting edge: Decreased accumulation and regulatory function of CD4+ CD25(high) T cells in human STAT5b deficiency. J Immunol 177 (2006) 2770-2774
-
(2006)
J Immunol
, vol.177
, pp. 2770-2774
-
-
Cohen, A.C.1
Nadeau, K.C.2
Tu, W.3
Hwa, V.4
Dionis, K.5
Bezrodnik, L.6
-
51
-
-
41449114038
-
The biology of interleukin-2
-
Dec 6 [epub ahead of print]
-
Malek T.R. The biology of interleukin-2. Annu Rev Immunol (2007) Dec 6 [epub ahead of print]
-
(2007)
Annu Rev Immunol
-
-
Malek, T.R.1
-
52
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4 (2003) 330-336
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
53
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
54
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin M.A., Rasmussen J.P., Fontenot J.D., Vasta V., Manganiello V.C., Beavo J.A., et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 445 (2007) 771-775
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
-
55
-
-
33947600584
-
Regulatory T cell development in the absence of functional Foxp3
-
Lin W., Haribhai D., Relland L.M., Truong N., Carlson M.R., Williams C.B., et al. Regulatory T cell development in the absence of functional Foxp3. Nat Immunol 8 (2007) 359-368
-
(2007)
Nat Immunol
, vol.8
, pp. 359-368
-
-
Lin, W.1
Haribhai, D.2
Relland, L.M.3
Truong, N.4
Carlson, M.R.5
Williams, C.B.6
-
56
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila T.A., Blaeser F., Ho N., Lederman H.M., Voulgaropoulos C., Helms C., et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 106 (2000) R75-R81
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
-
57
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams L.M., and Rudensky A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 8 (2007) 277-284
-
(2007)
Nat Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
58
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
Schubert L.A., Jeffery E., Zhang Y., Ramsdell F., and Ziegler S.F. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J Biol Chem 276 (2001) 37672-37679
-
(2001)
J Biol Chem
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
59
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson A., Kretschmer K., Frampton G.M., Jacobsen E.S., Polansky J.K., MacIsaac K.D., et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 445 (2007) 931-935
-
(2007)
Nature
, vol.445
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
Jacobsen, E.S.4
Polansky, J.K.5
MacIsaac, K.D.6
-
60
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng Y., Josefowicz S.Z., Kas A., Chu T.T., Gavin M.A., and Rudensky A.Y. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 445 (2007) 936-940
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
61
-
-
34248379172
-
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression
-
Li B., Samanta A., Song X., Iacono K.T., Bembas K., Tao R., et al. FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci U S A 104 (2007) 4571-4576
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4571-4576
-
-
Li, B.1
Samanta, A.2
Song, X.3
Iacono, K.T.4
Bembas, K.5
Tao, R.6
-
62
-
-
34547821980
-
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease
-
Li B., Samanta A., Song X., Iacono K.T., Brennan P., Chatila T.A., et al. FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int Immunol 19 (2007) 825-835
-
(2007)
Int Immunol
, vol.19
, pp. 825-835
-
-
Li, B.1
Samanta, A.2
Song, X.3
Iacono, K.T.4
Brennan, P.5
Chatila, T.A.6
-
63
-
-
34247215187
-
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
-
Ono M., Yaguchi H., Ohkura N., Kitabayashi I., Nagamura Y., Nomura T., et al. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature 446 (2007) 685-689
-
(2007)
Nature
, vol.446
, pp. 685-689
-
-
Ono, M.1
Yaguchi, H.2
Ohkura, N.3
Kitabayashi, I.4
Nagamura, Y.5
Nomura, T.6
-
64
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Wu Y., Borde M., Heissmeyer V., Feuerer M., Lapan A.D., Stroud J.C., et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126 (2006) 375-387
-
(2006)
Cell
, vol.126
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
Feuerer, M.4
Lapan, A.D.5
Stroud, J.C.6
-
65
-
-
27644449311
-
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
-
Allan S.E., Passerini L., Bacchetta R., Crellin N., Dai M., Orban P.C., et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest 115 (2005) 3276-3284
-
(2005)
J Clin Invest
, vol.115
, pp. 3276-3284
-
-
Allan, S.E.1
Passerini, L.2
Bacchetta, R.3
Crellin, N.4
Dai, M.5
Orban, P.C.6
-
66
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
Hill J.A., Feuerer M., Tash K., Haxhinasto S., Perez J., Melamed R., et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 27 (2007) 786-800
-
(2007)
Immunity
, vol.27
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
Haxhinasto, S.4
Perez, J.5
Melamed, R.6
-
67
-
-
36048986019
-
The regulatory T cell transcriptosome: e pluribus unum
-
Chatila T. The regulatory T cell transcriptosome: e pluribus unum. Immunity 27 (2007) 693-695
-
(2007)
Immunity
, vol.27
, pp. 693-695
-
-
Chatila, T.1
-
68
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198 (2003) 1875-1886
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
69
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini M.C., Becker C., Monteleone G., Pallone F., Galle P.R., and Neurath M.F. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 172 (2004) 5149-5153
-
(2004)
J Immunol
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
70
-
-
38349095578
-
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
-
Tone Y., Furuuchi K., Kojima Y., Tykocinski M.L., Greene M.I., and Tone M. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol 9 (2008) 194-202
-
(2008)
Nat Immunol
, vol.9
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
71
-
-
22144479379
-
Oral tolerance in the absence of naturally occurring Tregs
-
Mucida D., Kutchukhidze N., Erazo A., Russo M., Lafaille J.J., and Curotto de Lafaille M.A. Oral tolerance in the absence of naturally occurring Tregs. J Clin Invest 115 (2005) 1923-1933
-
(2005)
J Clin Invest
, vol.115
, pp. 1923-1933
-
-
Mucida, D.1
Kutchukhidze, N.2
Erazo, A.3
Russo, M.4
Lafaille, J.J.5
Curotto de Lafaille, M.A.6
-
72
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I., and von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 199 (2004) 1401-1408
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
von Boehmer, H.2
-
73
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S., Freyer J., Siewert C., Baron U., Olek S., Polansky J., et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 5 (2007) 169-178
-
(2007)
PLoS Biol
, vol.5
, pp. 169-178
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
Baron, U.4
Olek, S.5
Polansky, J.6
-
74
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage
-
O'Garra A., Vieira P.L., Vieira P., and Goldfeld A.E. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 114 (2004) 1372-1378
-
(2004)
J Clin Invest
, vol.114
, pp. 1372-1378
-
-
O'Garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
75
-
-
33749522704
-
Stochastic monoallelic expression of IL-10 in T cells
-
Calado D.P., Paixao T., Holmberg D., and Haury M. Stochastic monoallelic expression of IL-10 in T cells. J Immunol 177 (2006) 5358-5364
-
(2006)
J Immunol
, vol.177
, pp. 5358-5364
-
-
Calado, D.P.1
Paixao, T.2
Holmberg, D.3
Haury, M.4
-
76
-
-
33845453812
-
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse
-
Kamanaka M., Kim S.T., Wan Y.Y., Sutterwala F.S., Lara-Tejero M., Galan J.E., et al. Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity 25 (2006) 941-952
-
(2006)
Immunity
, vol.25
, pp. 941-952
-
-
Kamanaka, M.1
Kim, S.T.2
Wan, Y.Y.3
Sutterwala, F.S.4
Lara-Tejero, M.5
Galan, J.E.6
-
77
-
-
34548131112
-
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
-
Maynard C.L., Harrington L.E., Janowski K.M., Oliver J.R., Zindl C.L., Rudensky A.Y., et al. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10. Nat Immunol 8 (2007) 931-941
-
(2007)
Nat Immunol
, vol.8
, pp. 931-941
-
-
Maynard, C.L.1
Harrington, L.E.2
Janowski, K.M.3
Oliver, J.R.4
Zindl, C.L.5
Rudensky, A.Y.6
-
78
-
-
34047163404
-
Mechanisms of allergen-specific immunotherapy
-
Akdis M., and Akdis C.A. Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol 119 (2007) 780-791
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 780-791
-
-
Akdis, M.1
Akdis, C.A.2
-
79
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6 (2005) 1123-1132
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
-
80
-
-
33744984785
-
Th17: an effector CD4 T cell lineage with regulatory T cell ties
-
Weaver C.T., Harrington L.E., Mangan P.R., Gavrieli M., and Murphy K.M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24 (2006) 677-688
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
81
-
-
25144515561
-
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae
-
Happel K.I., Dubin P.J., Zheng M., Ghilardi N., Lockhart C., Quinton L.J., et al. Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med 202 (2005) 761-769
-
(2005)
J Exp Med
, vol.202
, pp. 761-769
-
-
Happel, K.I.1
Dubin, P.J.2
Zheng, M.3
Ghilardi, N.4
Lockhart, C.5
Quinton, L.J.6
-
82
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez E.V., Napolitani G., Lanzavecchia A., and Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 8 (2007) 942-949
-
(2007)
Nat Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
83
-
-
34249026701
-
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
LeibundGut-Landmann S., Gross O., Robinson M.J., Osorio F., Slack E.C., Tsoni S.V., et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol 8 (2007) 630-638
-
(2007)
Nat Immunol
, vol.8
, pp. 630-638
-
-
LeibundGut-Landmann, S.1
Gross, O.2
Robinson, M.J.3
Osorio, F.4
Slack, E.C.5
Tsoni, S.V.6
-
84
-
-
34249068562
-
Antifungal defense turns 17
-
Palm N.W., and Medzhitov R. Antifungal defense turns 17. Nat Immunol 8 (2007) 549-551
-
(2007)
Nat Immunol
, vol.8
, pp. 549-551
-
-
Palm, N.W.1
Medzhitov, R.2
-
86
-
-
33847667225
-
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
-
Afzali B., Lombardi G., Lechler R.I., and Lord G.M. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 148 (2007) 32-46
-
(2007)
Clin Exp Immunol
, vol.148
, pp. 32-46
-
-
Afzali, B.1
Lombardi, G.2
Lechler, R.I.3
Lord, G.M.4
-
87
-
-
35648935980
-
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge
-
He R., Oyoshi M.K., Jin H., and Geha R.S. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci U S A 104 (2007) 15817-15822
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15817-15822
-
-
He, R.1
Oyoshi, M.K.2
Jin, H.3
Geha, R.S.4
-
88
-
-
33751506710
-
Interleukin-17 is a negative regulator of established allergic asthma
-
Schnyder-Candrian S., Togbe D., Couillin I., Mercier I., Brombacher F., Quesniaux V., et al. Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med 203 (2006) 2715-2725
-
(2006)
J Exp Med
, vol.203
, pp. 2715-2725
-
-
Schnyder-Candrian, S.1
Togbe, D.2
Couillin, I.3
Mercier, I.4
Brombacher, F.5
Quesniaux, V.6
-
89
-
-
33645248319
-
The roles of orphan nuclear receptors in the development and function of the immune system
-
Dzhagalov I., Zhang N., and He Y.W. The roles of orphan nuclear receptors in the development and function of the immune system. Cell Mol Immunol 1 (2004) 401-407
-
(2004)
Cell Mol Immunol
, vol.1
, pp. 401-407
-
-
Dzhagalov, I.1
Zhang, N.2
He, Y.W.3
-
90
-
-
0035238364
-
The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes
-
Jetten A.M., Kurebayashi S., and Ueda E. The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes. Prog Nucleic Acid Res Mol Biol 69 (2001) 205-247
-
(2001)
Prog Nucleic Acid Res Mol Biol
, vol.69
, pp. 205-247
-
-
Jetten, A.M.1
Kurebayashi, S.2
Ueda, E.3
-
91
-
-
0032217092
-
RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells
-
He Y.W., Deftos M.L., Ojala E.W., and Bevan M.J. RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity 9 (1998) 797-806
-
(1998)
Immunity
, vol.9
, pp. 797-806
-
-
He, Y.W.1
Deftos, M.L.2
Ojala, E.W.3
Bevan, M.J.4
-
92
-
-
0034733039
-
Requirement for RORgamma in thymocyte survival and lymphoid organ development
-
Sun Z., Unutmaz D., Zou Y.R., Sunshine M.J., Pierani A., Brenner-Morton S., et al. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science 288 (2000) 2369-2373
-
(2000)
Science
, vol.288
, pp. 2369-2373
-
-
Sun, Z.1
Unutmaz, D.2
Zou, Y.R.3
Sunshine, M.J.4
Pierani, A.5
Brenner-Morton, S.6
-
93
-
-
0034730131
-
Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis
-
Kurebayashi S., Ueda E., Sakaue M., Patel D.D., Medvedev A., Zhang F., et al. Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. Proc Natl Acad Sci U S A 97 (2000) 10132-10137
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10132-10137
-
-
Kurebayashi, S.1
Ueda, E.2
Sakaue, M.3
Patel, D.D.4
Medvedev, A.5
Zhang, F.6
-
94
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov II, McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126 (2006) 1121-1133
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov II1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
-
95
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORalpha and RORgamma
-
Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORalpha and RORgamma. Immunity 28 (2008) 29-39
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
-
96
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson N.J., Boniface K., Chan J.R., McKenzie B.S., Blumenschein W.M., Mattson J.D., et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 8 (2007) 950-957
-
(2007)
Nat Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
-
97
-
-
34548125310
-
T(H)-17 differentiation: of mice and men
-
Laurence A., and O'Shea J.J. T(H)-17 differentiation: of mice and men. Nat Immunol 8 (2007) 903-905
-
(2007)
Nat Immunol
, vol.8
, pp. 903-905
-
-
Laurence, A.1
O'Shea, J.J.2
-
98
-
-
39449101603
-
Transcriptional regulation of Th17 cell differentiation
-
Ivanov II, Zhou L., and Littman D.R. Transcriptional regulation of Th17 cell differentiation. Semin Immunol 19 (2007) 409-417
-
(2007)
Semin Immunol
, vol.19
, pp. 409-417
-
-
Ivanov II1
Zhou, L.2
Littman, D.R.3
-
99
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T., Bettelli E., Gao W., Awasthi A., Jager A., Strom T.B., et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 448 (2007) 484-487
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jager, A.5
Strom, T.B.6
-
100
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L., Ivanov II, Spolski R., Min R., Shenderov K., Egawa T., et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 8 (2007) 967-974
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov II2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
-
101
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R., Yang X.O., Martinez G., Zhang Y., Panopoulos A.D., Ma L., et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448 (2007) 480-483
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
Zhang, Y.4
Panopoulos, A.D.5
Ma, L.6
-
102
-
-
34548128307
-
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
-
Brustle A., Heink S., Huber M., Rosenplanter C., Stadelmann C., Yu P., et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol 8 (2007) 958-966
-
(2007)
Nat Immunol
, vol.8
, pp. 958-966
-
-
Brustle, A.1
Heink, S.2
Huber, M.3
Rosenplanter, C.4
Stadelmann, C.5
Yu, P.6
-
103
-
-
35348960378
-
STAT3 mutations in the hyper-IgE syndrome
-
Holland S.M., DeLeo F.R., Elloumi H.Z., Hsu A.P., Uzel G., Brodsky N., et al. STAT3 mutations in the hyper-IgE syndrome. N Engl J Med 357 (2007) 1608-1619
-
(2007)
N Engl J Med
, vol.357
, pp. 1608-1619
-
-
Holland, S.M.1
DeLeo, F.R.2
Elloumi, H.Z.3
Hsu, A.P.4
Uzel, G.5
Brodsky, N.6
-
104
-
-
34548317417
-
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
-
Minegishi Y., Saito M., Tsuchiya S., Tsuge I., Takada H., Hara T., et al. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature 448 (2007) 1058-1062
-
(2007)
Nature
, vol.448
, pp. 1058-1062
-
-
Minegishi, Y.1
Saito, M.2
Tsuchiya, S.3
Tsuge, I.4
Takada, H.5
Hara, T.6
-
105
-
-
33646752928
-
Transcription factors in asthma: are transcription factors a new target for asthma therapy?
-
Roth M., and Black J.L. Transcription factors in asthma: are transcription factors a new target for asthma therapy?. Curr Drug Targets 7 (2006) 589-595
-
(2006)
Curr Drug Targets
, vol.7
, pp. 589-595
-
-
Roth, M.1
Black, J.L.2
-
107
-
-
34748920671
-
Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?
-
Newton R., and Holden N.S. Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?. Mol Pharmacol 72 (2007) 799-809
-
(2007)
Mol Pharmacol
, vol.72
, pp. 799-809
-
-
Newton, R.1
Holden, N.S.2
-
108
-
-
20744443470
-
Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment
-
Jee Y.K., Gilmour J., Kelly A., Bowen H., Richards D., Soh C., et al. Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment. J Biol Chem 280 (2005) 23243-23250
-
(2005)
J Biol Chem
, vol.280
, pp. 23243-23250
-
-
Jee, Y.K.1
Gilmour, J.2
Kelly, A.3
Bowen, H.4
Richards, D.5
Soh, C.6
-
109
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
Ito K., Yamamura S., Essilfie-Quaye S., Cosio B., Ito M., Barnes P.J., et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 203 (2006) 7-13
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
-
110
-
-
33744477341
-
How corticosteroids control inflammation: Quintiles Prize Lecture 2005
-
Barnes P.J. How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 148 (2006) 245-254
-
(2006)
Br J Pharmacol
, vol.148
, pp. 245-254
-
-
Barnes, P.J.1
-
111
-
-
33745288812
-
Emerging possibilities in the development and function of regulatory T cells
-
Wing K., Fehervari Z., and Sakaguchi S. Emerging possibilities in the development and function of regulatory T cells. Int Immunol 18 (2006) 991-1000
-
(2006)
Int Immunol
, vol.18
, pp. 991-1000
-
-
Wing, K.1
Fehervari, Z.2
Sakaguchi, S.3
-
112
-
-
34247160468
-
Therapeutic use of T regulatory cells
-
Verbsky J.W. Therapeutic use of T regulatory cells. Curr Opin Rheumatol 19 (2007) 252-258
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 252-258
-
-
Verbsky, J.W.1
-
113
-
-
34547214205
-
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
-
Roncarolo M.G., and Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 7 (2007) 585-598
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 585-598
-
-
Roncarolo, M.G.1
Battaglia, M.2
-
114
-
-
33746369415
-
Regulatory T-cell physiology and application to treat autoimmunity
-
Tang Q., and Bluestone J.A. Regulatory T-cell physiology and application to treat autoimmunity. Immunol Rev 212 (2006) 217-237
-
(2006)
Immunol Rev
, vol.212
, pp. 217-237
-
-
Tang, Q.1
Bluestone, J.A.2
-
115
-
-
38049020656
-
Prevention of acute and chronic allograft rejection with CD4(+)CD25(+)Foxp3(+) regulatory T lymphocytes
-
Joffre O., Santolaria T., Calise D., Saati T.A., Hudrisier D., Romagnoli P., et al. Prevention of acute and chronic allograft rejection with CD4(+)CD25(+)Foxp3(+) regulatory T lymphocytes. Nat Med 14 (2008) 88-92
-
(2008)
Nat Med
, vol.14
, pp. 88-92
-
-
Joffre, O.1
Santolaria, T.2
Calise, D.3
Saati, T.A.4
Hudrisier, D.5
Romagnoli, P.6
-
116
-
-
37549032709
-
Generation of potent and stable human CD4(+) T regulatory cells by activation-independent expression of FOXP3
-
Allan S.E., Alstad A.N., Merindol N., Crellin N.K., Amendola M., Bacchetta R., et al. Generation of potent and stable human CD4(+) T regulatory cells by activation-independent expression of FOXP3. Mol Ther 16 (2008) 194-202
-
(2008)
Mol Ther
, vol.16
, pp. 194-202
-
-
Allan, S.E.1
Alstad, A.N.2
Merindol, N.3
Crellin, N.K.4
Amendola, M.5
Bacchetta, R.6
-
117
-
-
20444373376
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
-
Battaglia M., Stabilini A., and Roncarolo M.G. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 105 (2005) 4743-4748
-
(2005)
Blood
, vol.105
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
118
-
-
38049177784
-
Differential impact of mTOR inhibition on CD4+CD25+Foxp3+ regulatory T cells as compared to conventional CD4+ T cells
-
Zeiser R., Leveson-Gower D.B., Zambricki E.A., Kambham N., Beilhack A., Loh J., et al. Differential impact of mTOR inhibition on CD4+CD25+Foxp3+ regulatory T cells as compared to conventional CD4+ T cells. Blood 111 (2008) 453-462
-
(2008)
Blood
, vol.111
, pp. 453-462
-
-
Zeiser, R.1
Leveson-Gower, D.B.2
Zambricki, E.A.3
Kambham, N.4
Beilhack, A.5
Loh, J.6
-
119
-
-
35948980739
-
Deacetylase inhibition promotes the generation and function of regulatory T cells
-
Tao R., de Zoeten E.F., Ozkaynak E., Chen C., Wang L., Porrett P.M., et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 13 (2007) 1299-1307
-
(2007)
Nat Med
, vol.13
, pp. 1299-1307
-
-
Tao, R.1
de Zoeten, E.F.2
Ozkaynak, E.3
Chen, C.4
Wang, L.5
Porrett, P.M.6
-
120
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
Benson M.J., Pino-Lagos K., Rosemblatt M., and Noelle R.J. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med 204 (2007) 1765-1774
-
(2007)
J Exp Med
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
121
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
Coombes J.L., Siddiqui K.R., Arancibia-Carcamo C.V., Hall J., Sun C.M., Belkaid Y., et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 204 (2007) 1757-1764
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
Hall, J.4
Sun, C.M.5
Belkaid, Y.6
-
122
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 317 (2007) 256-260
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
-
123
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun C.M., Hall J.A., Blank R.B., Bouladoux N., Oukka M., Mora J.R., et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 204 (2007) 1775-1785
-
(2007)
J Exp Med
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
Bouladoux, N.4
Oukka, M.5
Mora, J.R.6
-
124
-
-
35748934494
-
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells
-
Kang S.G., Lim H.W., Andrisani O.M., Broxmeyer H.E., and Kim C.H. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol 179 (2007) 3724-3733
-
(2007)
J Immunol
, vol.179
, pp. 3724-3733
-
-
Kang, S.G.1
Lim, H.W.2
Andrisani, O.M.3
Broxmeyer, H.E.4
Kim, C.H.5
-
125
-
-
38949164425
-
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
-
Elias K.M., Laurence A., Davidson T.S., Stephens G., Kanno Y., Shevach E.M., et al. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111 (2008) 1013-1020
-
(2008)
Blood
, vol.111
, pp. 1013-1020
-
-
Elias, K.M.1
Laurence, A.2
Davidson, T.S.3
Stephens, G.4
Kanno, Y.5
Shevach, E.M.6
-
126
-
-
34547751351
-
Oral tolerance: is it all retinoic acid?
-
von Boehmer H. Oral tolerance: is it all retinoic acid?. J Exp Med 204 (2007) 1737-1739
-
(2007)
J Exp Med
, vol.204
, pp. 1737-1739
-
-
von Boehmer, H.1
-
127
-
-
34648825284
-
Extra-intestinal manifestations of gastro-intestinal allergy: effector and regulatory T cells in the balance
-
Chatila T.A. Extra-intestinal manifestations of gastro-intestinal allergy: effector and regulatory T cells in the balance. Clin Exp Allergy 37 (2007) 1417-1418
-
(2007)
Clin Exp Allergy
, vol.37
, pp. 1417-1418
-
-
Chatila, T.A.1
-
128
-
-
1642368362
-
Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases
-
Chen X.L., and Kunsch C. Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases. Curr Pharm Des 10 (2004) 879-891
-
(2004)
Curr Pharm Des
, vol.10
, pp. 879-891
-
-
Chen, X.L.1
Kunsch, C.2
-
129
-
-
4344688670
-
Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals
-
Li N., Alam J., Venkatesan M.I., Eiguren-Fernandez A., Schmitz D., Di Stefano E., et al. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. J Immunol 173 (2004) 3467-3481
-
(2004)
J Immunol
, vol.173
, pp. 3467-3481
-
-
Li, N.1
Alam, J.2
Venkatesan, M.I.3
Eiguren-Fernandez, A.4
Schmitz, D.5
Di Stefano, E.6
-
130
-
-
0037188518
-
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
-
Fahey J.W., Haristoy X., Dolan P.M., Kensler T.W., Scholtus I., Stephenson K.K., et al. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proc Natl Acad Sci U S A 99 (2002) 7610-7615
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7610-7615
-
-
Fahey, J.W.1
Haristoy, X.2
Dolan, P.M.3
Kensler, T.W.4
Scholtus, I.5
Stephenson, K.K.6
-
131
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler T.W., Wakabayashi N., and Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 47 (2007) 89-116
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
133
-
-
34247535550
-
Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence
-
Kim H.J., Barajas B., Chan R.C., and Nel A.E. Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence. J Allergy Clin Immunol 119 (2007) 1225-1233
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1225-1233
-
-
Kim, H.J.1
Barajas, B.2
Chan, R.C.3
Nel, A.E.4
-
134
-
-
33744729373
-
Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
-
Ma Q., Battelli L., and Hubbs A.F. Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2. Am J Pathol 168 (2006) 1960-1974
-
(2006)
Am J Pathol
, vol.168
, pp. 1960-1974
-
-
Ma, Q.1
Battelli, L.2
Hubbs, A.F.3
-
135
-
-
0036007313
-
Role of NRF2 in protection against hyperoxic lung injury in mice
-
Cho H.Y., Jedlicka A.E., Reddy S.P., Kensler T.W., Yamamoto M., Zhang L.Y., et al. Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26 (2002) 175-182
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 175-182
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Reddy, S.P.3
Kensler, T.W.4
Yamamoto, M.5
Zhang, L.Y.6
-
136
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
Rangasamy T., Guo J., Mitzner W.A., Roman J., Singh A., Fryer A.D., et al. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 202 (2005) 47-59
-
(2005)
J Exp Med
, vol.202
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
-
137
-
-
33644652410
-
Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma
-
Li N., and Nel A.E. Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma. Antioxid Redox Signal 8 (2006) 88-98
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 88-98
-
-
Li, N.1
Nel, A.E.2
-
138
-
-
34249678457
-
T(H)1 cells control themselves by producing interleukin-10
-
O'Garra A., and Vieira P. T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol 7 (2007) 425-428
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 425-428
-
-
O'Garra, A.1
Vieira, P.2
|