-
1
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22, 531-562 (2004).
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
2
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot, J.D. & Rudensky, A.Y. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol. 6, 331-337 (2005).
-
(2005)
Nat. Immunol
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
3
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., Sarukhan, A., Klein, L. & von Boehmer, H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3, 756-763 (2002).
-
(2002)
Nat. Immunol
, vol.3
, pp. 756-763
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
von Boehmer, H.4
-
4
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2, 301-306 (2001).
-
(2001)
Nat. Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
6
-
-
33744786828
-
+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage
-
+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage. Proc. Natl. Acad. Sci. USA 103, 8453-8458 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8453-8458
-
-
Cabarrocas, J.1
-
7
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
-
Hsieh, C.S., Zheng, Y., Liang, Y., Fontenot, J.D. & Rudensky, A.Y. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat. Immunol. 7, 401-410 (2006).
-
(2006)
Nat. Immunol
, vol.7
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
9
-
-
0025317650
-
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
-
Lyon, M.F., Peters, J., Glenister, P.H., Ball, S. & Wright, E. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc. Natl. Acad. Sci. USA 87, 2433-2437 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2433-2437
-
-
Lyon, M.F.1
Peters, J.2
Glenister, P.H.3
Ball, S.4
Wright, E.5
-
10
-
-
0026178213
-
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
-
Godfrey, V.L., Wilkinson, J.E. & Russell, L.B. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am. J. Pathol. 138, 1379-1387 (1991).
-
(1991)
Am. J. Pathol
, vol.138
, pp. 1379-1387
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Russell, L.B.3
-
12
-
-
27644519459
-
Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice
-
Lin, W. et al. Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice. J. Allergy Clin. Immunol. 116, 1106-1115 (2005).
-
(2005)
J. Allergy Clin. Immunol
, vol.116
, pp. 1106-1115
-
-
Lin, W.1
-
13
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T.A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-R81 (2000).
-
(2000)
J. Clin. Invest
, vol.106
-
-
Chatila, T.A.1
-
14
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R.S. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27, 18-20 (2001).
-
(2001)
Nat. Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
15
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C.L. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27, 20-21 (2001).
-
(2001)
Nat. Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
16
-
-
0036568942
-
+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol. 168, 4399-4405 (2002).
-
(2002)
J. Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
-
17
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
18
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
van Santen, H.M., Benoist, C. & Mathis, D. Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. J. Exp. Med. 200, 1221-1230 (2004).
-
(2004)
J. Exp. Med
, vol.200
, pp. 1221-1230
-
-
van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
19
-
-
33646240855
-
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
-
Gavin, M.A. et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc. Natl. Acad. Sci. USA 103, 6659-6664 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6659-6664
-
-
Gavin, M.A.1
-
20
-
-
0029946516
-
Administration of anti-interleukin-2 receptor α antibody in vivo induces localized autoimmune disease
-
Taguchi, O. & Takahashi, T. Administration of anti-interleukin-2 receptor α antibody in vivo induces localized autoimmune disease. Eur. J. Immunol. 26, 1608-1612 (1996).
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 1608-1612
-
-
Taguchi, O.1
Takahashi, T.2
-
21
-
-
0037097503
-
+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
-
+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J. Immunol. 168, 5979-5983 (2002).
-
(2002)
J. Immunol
, vol.168
, pp. 5979-5983
-
-
McHugh, R.S.1
Shevach, E.M.2
-
22
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Wu, Y. et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 126, 375-387 (2006).
-
(2006)
Cell
, vol.126
, pp. 375-387
-
-
Wu, Y.1
-
23
-
-
33644800026
-
Structure of the forkhead domain of FOXP2 bound to DNA
-
Stroud, J.C. et al. Structure of the forkhead domain of FOXP2 bound to DNA. Structure 14, 159-166 (2006).
-
(2006)
Structure
, vol.14
, pp. 159-166
-
-
Stroud, J.C.1
-
24
-
-
33747762947
-
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor
-
Lopes, J.E. et al. Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor. J. Immunol. 177, 3133-3142 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 3133-3142
-
-
Lopes, J.E.1
-
25
-
-
33847370194
-
Regulatory T cells dynamically control the primary immune response to foreign antigen
-
in the press
-
Haribhai, D. et al. Regulatory T cells dynamically control the primary immune response to foreign antigen. J. Immunol. (in the press).
-
J. Immunol
-
-
Haribhai, D.1
-
26
-
-
0026553435
-
Activation events during thymic selection
-
Bendelac, A., Matzinger, P., Seder, R.A., Paul, W.E. & Schwartz, R.H. Activation events during thymic selection. J. Exp. Med. 175, 731-742 (1992).
-
(1992)
J. Exp. Med
, vol.175
, pp. 731-742
-
-
Bendelac, A.1
Matzinger, P.2
Seder, R.A.3
Paul, W.E.4
Schwartz, R.H.5
-
27
-
-
0035988219
-
A potential role for CD69 in thymocyte emigration
-
Feng, C. et al. A potential role for CD69 in thymocyte emigration. Int. Immunol. 14, 535-544 (2002).
-
(2002)
Int. Immunol
, vol.14
, pp. 535-544
-
-
Feng, C.1
-
28
-
-
33745817085
-
+ T reg cells
-
+ T reg cells. J. Exp. Med. 203, 1701-1711 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
-
29
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki, N. et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203, 1693-1700 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
-
30
-
-
10744221289
-
+ regulatory T cells
-
+ regulatory T cells. J. Exp. Med. 199, 303-313 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 303-313
-
-
Huehn, J.1
-
31
-
-
33746377279
-
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
-
Izcue, A., Coombes, J.L. & Powrie, F. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol. Rev. 212, 256-271 (2006).
-
(2006)
Immunol. Rev
, vol.212
, pp. 256-271
-
-
Izcue, A.1
Coombes, J.L.2
Powrie, F.3
-
32
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
-
Fontenot, J.D. et al. Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity 22, 329-341 (2005).
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
-
35
-
-
33748460087
-
+ natural regulatory T cells revealed by DNA microarray analysis
-
+ natural regulatory T cells revealed by DNA microarray analysis. Int. Immunol. 18, 1197-1209 (2006).
-
(2006)
Int. Immunol
, vol.18
, pp. 1197-1209
-
-
Sugimoto, N.1
-
36
-
-
0035175548
-
Defective T cell activation and autoimmune disorder in Stra13-deficient mice
-
Sun, H., Lu, B., Li, R.Q., Flavell, R.A. & Taneja, R. Defective T cell activation and autoimmune disorder in Stra13-deficient mice. Nat. Immunol. 2, 1040-1047 (2001).
-
(2001)
Nat. Immunol
, vol.2
, pp. 1040-1047
-
-
Sun, H.1
Lu, B.2
Li, R.Q.3
Flavell, R.A.4
Taneja, R.5
-
37
-
-
0036745068
-
Orphan nuclear receptors in T lymphocyte development
-
He, Y.W. Orphan nuclear receptors in T lymphocyte development. J. Leukoc. Biol. 72, 440-446 (2002).
-
(2002)
J. Leukoc. Biol
, vol.72
, pp. 440-446
-
-
He, Y.W.1
-
38
-
-
8544234990
-
Recent developments in the transcriptional regulation of cytolytic effector cells
-
Glimcher, L.H., Townsend, M.J., Sullivan, B.M. & Lord, G.M. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat. Rev. Immunol. 4, 900-911 (2004).
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 900-911
-
-
Glimcher, L.H.1
Townsend, M.J.2
Sullivan, B.M.3
Lord, G.M.4
-
39
-
-
0035098106
-
Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential
-
Kim, C.H. et al. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107, 595-601 (2001).
-
(2001)
J. Clin. Invest
, vol.107
, pp. 595-601
-
-
Kim, C.H.1
-
41
-
-
0035813231
-
-
Schubert, L.A., Jeffery, E., Zhang, Y., Ramsdell, F. & Ziegler, S.F. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276, 37672-37679 (2001).
-
Schubert, L.A., Jeffery, E., Zhang, Y., Ramsdell, F. & Ziegler, S.F. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276, 37672-37679 (2001).
-
-
-
-
42
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
Bettelli, E., Dastrange, M. & Oukka, M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc. Natl. Acad. Sci. USA 102, 5138-5143 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
43
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim, J.M., Rasmussen, J.P. & Rudensky, A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8, 191-197 (2007).
-
(2007)
Nat. Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
44
-
-
33745296472
-
+ regulatory T cells is indexed to the number of IL-2-producing cells
-
+ regulatory T cells is indexed to the number of IL-2-producing cells. J. Immunol. 177, 192-200 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 192-200
-
-
Almeida, A.R.1
Zaragoza, B.2
Freitas, A.A.3
-
45
-
-
33749320682
-
Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7
-
Peffault de Latour, R. et al. Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7. Blood 108, 2300-2306 (2006).
-
(2006)
Blood
, vol.108
, pp. 2300-2306
-
-
Peffault de Latour, R.1
-
46
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
Grossman, W.J. et al. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 21, 589-601 (2004).
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
-
47
-
-
13544271161
-
+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
-
+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J. Immunol. 174, 1783-1786 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 1783-1786
-
-
Gondek, D.C.1
Lu, L.F.2
Quezada, S.A.3
Sakaguchi, S.4
Noelle, R.J.5
-
49
-
-
0030008349
-
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
-
Lakso, M. et al. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl. Acad. Sci. USA 93 5860-5865 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
-
50
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman, R.C. et al. Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
|