Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

Annual Review of Pharmacology and Toxicology

Volumn 47, Issue , 2007, Pages 89-116

  Kensler, Thomas W ^a   Wakabayashi, Nobunao ^a   Biswal, Shyam ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Antioxidant response element; Cytoprotection; Gene expression; Knockout mice; Oxidative stress

Indexed keywords

3 NITROPROPIONIC ACID; ACTIN; BENZO[A]PYRENE; BLEOMYCIN; BUTYLCRESOL; CARCINOGEN; CARRAGEENAN; ELASTASE; ENDOTOXIN; GENE PRODUCT; MALONIC ACID; NITROSAMINE; OVALBUMIN; PARACETAMOL; PROTEIN KEAP1; TOBACCO SMOKE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AGING; ANTIOXIDANT RESPONSIVE ELEMENT; CARCINOGENESIS; CARCINOGENICITY; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CIGARETTE SMOKING; DEGENERATIVE DISEASE; ENVIRONMENTAL STRESS; EXHAUST GAS; GENE; GENE CONTROL; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HYPEROXIA; INNATE IMMUNITY; KEAP1 GENE; KNOCKOUT MOUSE; LIVER TOXICITY; LUNG TOXICITY; MOLECULAR RECOGNITION; NEUROTOXICITY; NONHUMAN; NRF2 GENE; OVARY DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIOXIDANTS; CELL SURVIVAL; CYTOPROTECTION; CYTOSKELETAL PROTEINS; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS;

MUS;

EID: 33847050801     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.46.120604.141046     Document Type: Review

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