-
1
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
J.A. Bluestone, and A.K. Abbas Natural versus adaptive regulatory T cells Nat Rev Immunol 3 2003 253 257
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 253-257
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
2
-
-
0041735102
-
Regulatory T cells control the development of allergic disease and asthma
-
D.T. Umetsu, O. Akbari, and R.H. Dekruyff Regulatory T cells control the development of allergic disease and asthma J Allergy Clin Immunol 112 2003 480 488
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 480-488
-
-
Umetsu, D.T.1
Akbari, O.2
Dekruyff, R.H.3
-
3
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
S. Sakaguchi Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses Annu Rev Immunol 22 2004 531 562
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
4
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
S. Read, V. Malmstrom, and F. Powrie Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation J Exp Med 192 2000 295 302
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
5
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
T. Takahashi, T. Tagami, S. Yamazaki, T. Uede, J. Shimizu, and N. Sakaguchi Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4 J Exp Med 192 2000 303 310
-
(2000)
J Exp Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
-
6
-
-
0036195161
-
CD4(+)CD25(+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
R.S. McHugh, M.J. Whitters, C.A. Piccirillo, D.A. Young, E.M. Shevach, and M. Collins CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor Immunity 16 2002 311 323
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
Young, D.A.4
Shevach, E.M.5
Collins, M.6
-
7
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
-
J. Shimizu, S. Yamazaki, T. Takahashi, Y. Ishida, and S. Sakaguchi Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance Nat Immunol 3 2002 135 142
-
(2002)
Nat Immunol
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
8
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
9
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J Immunol 155 1995 1151 1164
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
10
-
-
0036597371
-
CD4+ CD25+ suppressor T cells: More questions than answers
-
E.M. Shevach CD4+ CD25+ suppressor T cells: more questions than answers Nat Rev Immunol 2 2002 389 400
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
11
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
A.M. Thornton, and E.M. Shevach CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J Exp Med 188 1998 287 296
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
12
-
-
0037220923
-
CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice
-
D. Xu, H. Liu, M. Komai-Koma, C. Campbell, C. McSharry, and J. Alexander CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice J Immunol 170 2003 394 399
-
(2003)
J Immunol
, vol.170
, pp. 394-399
-
-
Xu, D.1
Liu, H.2
Komai-Koma, M.3
Campbell, C.4
McSharry, C.5
Alexander, J.6
-
13
-
-
2942709797
-
Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells
-
M. Stassen, H. Jonuleit, C. Muller, M. Klein, C. Richter, and T. Bopp Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells J Immunol 173 2004 267 274
-
(2004)
J Immunol
, vol.173
, pp. 267-274
-
-
Stassen, M.1
Jonuleit, H.2
Muller, C.3
Klein, M.4
Richter, C.5
Bopp, T.6
-
14
-
-
0141449974
-
CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
-
S. Suvas, U. Kumaraguru, C.D. Pack, S. Lee, and B.T. Rouse CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses J Exp Med 198 2003 889 901
-
(2003)
J Exp Med
, vol.198
, pp. 889-901
-
-
Suvas, S.1
Kumaraguru, U.2
Pack, C.D.3
Lee, S.4
Rouse, B.T.5
-
15
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
H. von Boehmer Mechanisms of suppression by suppressor T cells Nat Immunol 6 2005 338 344
-
(2005)
Nat Immunol
, vol.6
, pp. 338-344
-
-
Von Boehmer, H.1
-
16
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
W.J. Grossman, J.W. Verbsky, W. Barchet, M. Colonna, J.P. Atkinson, and T.J. Ley Human T regulatory cells can use the perforin pathway to cause autologous target cell death Immunity 21 2004 589 601
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
17
-
-
0141703239
-
CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes
-
E.A. Green, L. Gorelik, C.M. McGregor, E.H. Tran, and R.A. Flavell CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes Proc Natl Acad Sci U S A 100 2003 10878 10883
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 10878-10883
-
-
Green, E.A.1
Gorelik, L.2
McGregor, C.M.3
Tran, E.H.4
Flavell, R.A.5
-
18
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
M.L. Chen, M.J. Pittet, L. Gorelik, R.A. Flavell, R. Weissleder, and H. von Boehmer Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo Proc Natl Acad Sci U S A 102 2005 419 424
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, pp. 419-424
-
-
Chen, M.L.1
Pittet, M.J.2
Gorelik, L.3
Flavell, R.A.4
Weissleder, R.5
Von Boehmer, H.6
-
19
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
-
J.C. Marie, J.J. Letterio, M. Gavin, and A.Y. Rudensky TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells J Exp Med 201 2005 1061 1067
-
(2005)
J Exp Med
, vol.201
, pp. 1061-1067
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
20
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
M. Asano, M. Toda, N. Sakaguchi, and S. Sakaguchi Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation J Exp Med 184 1996 387 396
-
(1996)
J Exp Med
, vol.184
, pp. 387-396
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
21
-
-
0033988289
-
Anergy and suppression regulate CD4(+) T cell responses to a self peptide
-
M.S. Jordan, M.P. Riley, H. von Boehmer, and A.J. Caton Anergy and suppression regulate CD4(+) T cell responses to a self peptide Eur J Immunol 30 2000 136 144
-
(2000)
Eur J Immunol
, vol.30
, pp. 136-144
-
-
Jordan, M.S.1
Riley, M.P.2
Von Boehmer, H.3
Caton, A.J.4
-
22
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
M.S. Jordan, A. Boesteanu, A.J. Reed, A.L. Petrone, A.E. Holenbeck, and M.A. Lerman Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide Nat Immunol 2 2001 301 306
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
-
23
-
-
0036568942
-
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
K. Kawahata, Y. Misaki, M. Yamauchi, S. Tsunekawa, K. Setoguchi, and J. Miyazaki Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression J Immunol 168 2002 4399 4405
-
(2002)
J Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
Misaki, Y.2
Yamauchi, M.3
Tsunekawa, S.4
Setoguchi, K.5
Miyazaki, J.6
-
25
-
-
9244244736
-
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
-
H.M. van Santen, C. Benoist, and D. Mathis Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells J Exp Med 200 2004 1221 1230
-
(2004)
J Exp Med
, vol.200
, pp. 1221-1230
-
-
Van Santen, H.M.1
Benoist, C.2
Mathis, D.3
-
26
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
J.D. Fontenot, J.P. Rasmussen, L.M. Williams, J.L. Dooley, A.G. Farr, and A.Y. Rudensky Regulatory T cell lineage specification by the forkhead transcription factor foxp3 Immunity 22 2005 329 341
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
27
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Y.Y. Wan, and R.A. Flavell Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter Proc Natl Acad Sci U S A 102 2005 5126 5131
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
28
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
T.R. Malek, and A.L. Bayer Tolerance, not immunity, crucially depends on IL-2 Nat Rev Immunol 4 2004 665 674
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 665-674
-
-
Malek, T.R.1
Bayer, A.L.2
-
29
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
W. Chen, W. Jin, N. Hardegen, K.J. Lei, L. Li, and N. Marinos Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 J Exp Med 198 2003 1875 1886
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
30
-
-
1242290580
-
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: The role of IL-2, TGF-beta, and IL-10
-
S.G. Zheng, J.H. Wang, J.D. Gray, H. Soucier, and D.A. Horwitz Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10 J Immunol 172 2004 5213 5221
-
(2004)
J Immunol
, vol.172
, pp. 5213-5221
-
-
Zheng, S.G.1
Wang, J.H.2
Gray, J.D.3
Soucier, H.4
Horwitz, D.A.5
-
31
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
-
M.C. Fantini, C. Becker, G. Monteleone, F. Pallone, P.R. Galle, and M.F. Neurath Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7 J Immunol 172 2004 5149 5153
-
(2004)
J Immunol
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
Becker, C.2
Monteleone, G.3
Pallone, F.4
Galle, P.R.5
Neurath, M.F.6
-
32
-
-
0346969978
-
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
-
M.R. Walker, D.J. Kasprowicz, V.H. Gersuk, A. Benard, M. Van Landeghen, and J.H. Buckner Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells J Clin Invest 112 2003 1437 1443
-
(2003)
J Clin Invest
, vol.112
, pp. 1437-1443
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
Benard, A.4
Van Landeghen, M.5
Buckner, J.H.6
-
33
-
-
8344275995
-
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
-
H. Yagi, T. Nomura, K. Nakamura, S. Yamazaki, T. Kitawaki, and S. Hori Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells Int Immunol 16 2004 1643 1656
-
(2004)
Int Immunol
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
Yamazaki, S.4
Kitawaki, T.5
Hori, S.6
-
34
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
I. Apostolou, and H. von Boehmer In vivo instruction of suppressor commitment in naive T cells J Exp Med 199 2004 1401 1408
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
35
-
-
22144479379
-
Oral tolerance in the absence of naturally occurring Tregs
-
D. Mucida, N. Kutchukhidze, A. Erazo, M. Russo, J.J. Lafaille, and M.A. Curotto de Lafaille Oral tolerance in the absence of naturally occurring Tregs J Clin Invest 115 2005 1923 1933
-
(2005)
J Clin Invest
, vol.115
, pp. 1923-1933
-
-
Mucida, D.1
Kutchukhidze, N.2
Erazo, A.3
Russo, M.4
Lafaille, J.J.5
Curotto De Lafaille, M.A.6
-
36
-
-
0035576221
-
The amount of scurfin protein determines peripheral T cell number and responsiveness
-
R. Khattri, D. Kasprowicz, T. Cox, M. Mortrud, M.W. Appleby, and M.E. Brunkow The amount of scurfin protein determines peripheral T cell number and responsiveness J Immunol 167 2001 6312 6320
-
(2001)
J Immunol
, vol.167
, pp. 6312-6320
-
-
Khattri, R.1
Kasprowicz, D.2
Cox, T.3
Mortrud, M.4
Appleby, M.W.5
Brunkow, M.E.6
-
37
-
-
0026178213
-
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
-
V.L. Godfrey, J.E. Wilkinson, and L.B. Russell X-linked lymphoreticular disease in the scurfy (sf) mutant mouse Am J Pathol 138 1991 1379 1387
-
(1991)
Am J Pathol
, vol.138
, pp. 1379-1387
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Russell, L.B.3
-
38
-
-
0025317650
-
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
-
M.F. Lyon, J. Peters, P.H. Glenister, S. Ball, and E. Wright The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome Proc Natl Acad Sci U S A 87 1990 2433 2437
-
(1990)
Proc Natl Acad Sci U S a
, vol.87
, pp. 2433-2437
-
-
Lyon, M.F.1
Peters, J.2
Glenister, P.H.3
Ball, S.4
Wright, E.5
-
39
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
J.D. Fontenot, M.A. Gavin, and A.Y. Rudensky Foxp3 programs the development and function of CD4+CD25+ regulatory T cells Nat Immunol 4 2003 330 336
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
40
-
-
27644519459
-
Allergic dysregulation and hyperimmunoglobulinemia e in Foxp3 mutant mice
-
W. Lin, N. Truong, W.J. Grossman, D. Haribhai, C.B. Williams, and J. Wang Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant mice J Allergy Clin Immunol 116 2005 1106 1115
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 1106-1115
-
-
Lin, W.1
Truong, N.2
Grossman, W.J.3
Haribhai, D.4
Williams, C.B.5
Wang, J.6
-
41
-
-
0035158734
-
Hyper immunoglobulin e response in mice with monoclonal populations of B and T lymphocytes
-
M.A. Curotto de Lafaille, S. Muriglan, M.J. Sunshine, Y. Lei, N. Kutchukhidze, and G.C. Furtado Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes J Exp Med 194 2001 1349 1359
-
(2001)
J Exp Med
, vol.194
, pp. 1349-1359
-
-
Curotto De Lafaille, M.A.1
Muriglan, S.2
Sunshine, M.J.3
Lei, Y.4
Kutchukhidze, N.5
Furtado, G.C.6
-
42
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
M.E. Brunkow, E.W. Jeffery, K.A. Hjerrild, B. Paeper, L.B. Clark, and S.A. Yasayko Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Nat Genet 27 2001 68 73
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
-
43
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
T.A. Chatila, F. Blaeser, N. Ho, H.M. Lederman, C. Voulgaropoulos, and C. Helms JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome J Clin Invest 106 2000 R75 R81
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
-
44
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
R.S. Wildin, F. Ramsdell, J. Peake, F. Faravelli, J.L. Casanova, and N. Buist X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy Nat Genet 27 2001 18 20
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
-
45
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
C.L. Bennett, J. Christie, F. Ramsdell, M.E. Brunkow, P.J. Ferguson, and L. Whitesell The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Nat Genet 27 2001 20 21
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
-
46
-
-
0036346861
-
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
R.S. Wildin, S. Smyk-Pearson, and A.H. Filipovich Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome J Med Genet 39 2002 537 545
-
(2002)
J Med Genet
, vol.39
, pp. 537-545
-
-
Wildin, R.S.1
Smyk-Pearson, S.2
Filipovich, A.H.3
-
47
-
-
13144261691
-
FOXP3 acts as a rheostat of the immune response
-
H.D. Ochs, S.F. Ziegler, and T.R. Torgerson FOXP3 acts as a rheostat of the immune response Immunol Rev 203 2005 156 164
-
(2005)
Immunol Rev
, vol.203
, pp. 156-164
-
-
Ochs, H.D.1
Ziegler, S.F.2
Torgerson, T.R.3
-
48
-
-
11144355358
-
Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome
-
D.S. Nieves, R.P. Phipps, S.J. Pollock, H.D. Ochs, Q. Zhu, and G.A. Scott Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome Arch Dermatol 140 2004 466 472
-
(2004)
Arch Dermatol
, vol.140
, pp. 466-472
-
-
Nieves, D.S.1
Phipps, R.P.2
Pollock, S.J.3
Ochs, H.D.4
Zhu, Q.5
Scott, G.A.6
-
49
-
-
0035821985
-
Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation
-
O. Baud, O. Goulet, D. Canioni, F. Le Deist, I. Radford, and D. Rieu Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation N Engl J Med 344 2001 1758 1762
-
(2001)
N Engl J Med
, vol.344
, pp. 1758-1762
-
-
Baud, O.1
Goulet, O.2
Canioni, D.3
Le Deist, F.4
Radford, I.5
Rieu, D.6
-
50
-
-
14644418544
-
A novel reduced-intensity stem cell transplant regimen for nonmalignant disorders
-
S. Shenoy, W.J. Grossman, J. DiPersio, L.C. Yu, D. Wilson, and Y.J. Barnes A novel reduced-intensity stem cell transplant regimen for nonmalignant disorders Bone Marrow Transplant 35 2005 345 352
-
(2005)
Bone Marrow Transplant
, vol.35
, pp. 345-352
-
-
Shenoy, S.1
Grossman, W.J.2
Dipersio, J.3
Yu, L.C.4
Wilson, D.5
Barnes, Y.J.6
-
51
-
-
0042591396
-
Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors
-
B. Wang, D. Lin, C. Li, and P. Tucker Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors J Biol Chem 278 2003 24259 24268
-
(2003)
J Biol Chem
, vol.278
, pp. 24259-24268
-
-
Wang, B.1
Lin, D.2
Li, C.3
Tucker, P.4
-
52
-
-
0347986673
-
Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions
-
S. Li, J. Weidenfeld, and E.E. Morrisey Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions Mol Cell Biol 24 2004 809 822
-
(2004)
Mol Cell Biol
, vol.24
, pp. 809-822
-
-
Li, S.1
Weidenfeld, J.2
Morrisey, E.E.3
-
53
-
-
0035813231
-
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
-
L.A. Schubert, E. Jeffery, Y. Zhang, F. Ramsdell, and S.F. Ziegler Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation J Biol Chem 276 2001 37672 37679
-
(2001)
J Biol Chem
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
54
-
-
17044393922
-
Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
-
E. Bettelli, M. Dastrange, and M. Oukka Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells Proc Natl Acad Sci U S A 102 2005 5138 5143
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, pp. 5138-5143
-
-
Bettelli, E.1
Dastrange, M.2
Oukka, M.3
-
55
-
-
0033105648
-
Cellular and molecular characterization of the scurfy mouse mutant
-
L.B. Clark, M.W. Appleby, M.E. Brunkow, J.E. Wilkinson, S.F. Ziegler, and F. Ramsdell Cellular and molecular characterization of the scurfy mouse mutant J Immunol 162 1999 2546 2554
-
(1999)
J Immunol
, vol.162
, pp. 2546-2554
-
-
Clark, L.B.1
Appleby, M.W.2
Brunkow, M.E.3
Wilkinson, J.E.4
Ziegler, S.F.5
Ramsdell, F.6
-
56
-
-
0028171297
-
CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
-
P.J. Blair, S.J. Bultman, J.C. Haas, B.T. Rouse, J.E. Wilkinson, and V.L. Godfrey CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse J Immunol 153 1994 3764 3774
-
(1994)
J Immunol
, vol.153
, pp. 3764-3774
-
-
Blair, P.J.1
Bultman, S.J.2
Haas, J.C.3
Rouse, B.T.4
Wilkinson, J.E.5
Godfrey, V.L.6
-
57
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
R. Khattri, T. Cox, S.A. Yasayko, and F. Ramsdell An essential role for Scurfin in CD4+CD25+ T regulatory cells Nat Immunol 4 2003 337 342
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
58
-
-
0035008978
-
SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo
-
T. Naka, H. Tsutsui, M. Fujimoto, Y. Kawazoe, H. Kohzaki, and Y. Morita SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo Immunity 14 2001 535 545
-
(2001)
Immunity
, vol.14
, pp. 535-545
-
-
Naka, T.1
Tsutsui, H.2
Fujimoto, M.3
Kawazoe, Y.4
Kohzaki, H.5
Morita, Y.6
-
59
-
-
0035873731
-
Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis
-
J.D. Gorham, J.T. Lin, J.L. Sung, L.A. Rudner, and M.A. French Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis J Immunol 166 2001 6413 6422
-
(2001)
J Immunol
, vol.166
, pp. 6413-6422
-
-
Gorham, J.D.1
Lin, J.T.2
Sung, J.L.3
Rudner, L.A.4
French, M.A.5
-
60
-
-
0347993107
-
Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome
-
C.J. Owen, C.E. Jennings, H. Imrie, A. Lachaux, N.A. Bridges, and T.D. Cheetham Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome J Clin Endocrinol Metab 88 2003 6034 6039
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 6034-6039
-
-
Owen, C.J.1
Jennings, C.E.2
Imrie, H.3
Lachaux, A.4
Bridges, N.A.5
Cheetham, T.D.6
-
61
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
T.R. Malek, A. Yu, V. Vincek, P. Scibelli, and L. Kong CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2 Immunity 17 2002 167 178
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
62
-
-
2542461255
-
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution
-
R.H. Buckley Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution Annu Rev Immunol 22 2004 625 655
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 625-655
-
-
Buckley, R.H.1
-
63
-
-
0028783963
-
Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells
-
B. Sadlack, J. Lohler, H. Schorle, G. Klebb, H. Haber, and E. Sickel Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells Eur J Immunol 25 1995 3053 3059
-
(1995)
Eur J Immunol
, vol.25
, pp. 3053-3059
-
-
Sadlack, B.1
Lohler, J.2
Schorle, H.3
Klebb, G.4
Haber, H.5
Sickel, E.6
-
64
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
B. Sadlack, H. Merz, H. Schorle, A. Schimpl, A.C. Feller, and I. Horak Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene Cell 75 1993 253 261
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
65
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
D.M. Willerford, J. Chen, J.A. Ferry, L. Davidson, A. Ma, and F.W. Alt Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment Immunity 3 1995 521 530
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
66
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
H. Suzuki, T.M. Kundig, C. Furlonger, A. Wakeham, E. Timms, and T. Matsuyama Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta Science 268 1995 1472 1476
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
Kundig, T.M.2
Furlonger, C.3
Wakeham, A.4
Timms, E.5
Matsuyama, T.6
-
67
-
-
0242580058
-
Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice
-
J.W. Snow, N. Abraham, M.C. Ma, B.G. Herndier, A.W. Pastuszak, and M.A. Goldsmith Loss of tolerance and autoimmunity affecting multiple organs in STAT5A/5B-deficient mice J Immunol 171 2003 5042 5050
-
(2003)
J Immunol
, vol.171
, pp. 5042-5050
-
-
Snow, J.W.1
Abraham, N.2
Ma, M.C.3
Herndier, B.G.4
Pastuszak, A.W.5
Goldsmith, M.A.6
-
68
-
-
0034965185
-
Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: Evidence for two distinct regulatory mechanisms
-
M. Wolf, A. Schimpl, and T. Hunig Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms Eur J Immunol 31 2001 1637 1645
-
(2001)
Eur J Immunol
, vol.31
, pp. 1637-1645
-
-
Wolf, M.1
Schimpl, A.2
Hunig, T.3
-
69
-
-
0030903027
-
Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor
-
N. Sharfe, H.K. Dadi, M. Shahar, and C.M. Roifman Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor Proc Natl Acad Sci U S A 94 1997 3168 3171
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 3168-3171
-
-
Sharfe, N.1
Dadi, H.K.2
Shahar, M.3
Roifman, C.M.4
-
70
-
-
0033920789
-
Human IL-2 receptor alpha chain deficiency
-
C.M. Roifman Human IL-2 receptor alpha chain deficiency Pediatr Res 48 2000 6 11
-
(2000)
Pediatr Res
, vol.48
, pp. 6-11
-
-
Roifman, C.M.1
-
72
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
E.A. Tivol, F. Borriello, A.N. Schweitzer, W.P. Lynch, J.A. Bluestone, and A.H. Sharpe Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 Immunity 3 1995 541 547
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
73
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
P. Waterhouse, J.M. Penninger, E. Timms, A. Wakeham, A. Shahinian, and K.P. Lee Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 Science 270 1995 985 988
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
-
74
-
-
2942738825
-
The emerging role of the CTLA-4 gene in autoimmune endocrinopathies
-
B. Vaidya, and S. Pearce The emerging role of the CTLA-4 gene in autoimmune endocrinopathies Eur J Endocrinol 150 2004 619 626
-
(2004)
Eur J Endocrinol
, vol.150
, pp. 619-626
-
-
Vaidya, B.1
Pearce, S.2
-
75
-
-
13144259647
-
Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis
-
G. Menasche, J. Feldmann, A. Fischer, and G. de Saint Basile Primary hemophagocytic syndromes point to a direct link between lymphocyte cytotoxicity and homeostasis Immunol Rev 203 2005 165 179
-
(2005)
Immunol Rev
, vol.203
, pp. 165-179
-
-
Menasche, G.1
Feldmann, J.2
Fischer, A.3
De Saint Basile, G.4
-
76
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
-
A. O'Garra, P.L. Vieira, P. Vieira, and A.E. Goldfeld IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage J Clin Invest 114 2004 1372 1378
-
(2004)
J Clin Invest
, vol.114
, pp. 1372-1378
-
-
O'Garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
77
-
-
0028158319
-
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
-
R. Bacchetta, M. Bigler, J.L. Touraine, R. Parkman, P.A. Tovo, and J. Abrams High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells J Exp Med 179 1994 493 502
-
(1994)
J Exp Med
, vol.179
, pp. 493-502
-
-
Bacchetta, R.1
Bigler, M.2
Touraine, J.L.3
Parkman, R.4
Tovo, P.A.5
Abrams, J.6
-
78
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
H. Groux, A. O'Garra, M. Bigler, M. Rouleau, S. Antonenko, and J.E. de Vries A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 1997 737 742
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
-
79
-
-
0035339884
-
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells
-
M.K. Levings, R. Sangregorio, F. Galbiati, S. Squadrone, R. de Waal Malefyt, and M.G. Roncarolo IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells J Immunol 166 2001 5530 5539
-
(2001)
J Immunol
, vol.166
, pp. 5530-5539
-
-
Levings, M.K.1
Sangregorio, R.2
Galbiati, F.3
Squadrone, S.4
De Waal Malefyt, R.5
Roncarolo, M.G.6
-
80
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
F.J. Barrat, D.J. Cua, A. Boonstra, D.F. Richards, C. Crain, and H.F. Savelkoul In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines J Exp Med 195 2002 603 616
-
(2002)
J Exp Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
Savelkoul, H.F.6
-
81
-
-
2442450433
-
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
-
P.L. Vieira, J.R. Christensen, S. Minaee, E.J. O'Neill, F.J. Barrat, and A. Boonstra IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells J Immunol 172 2004 5986 5993
-
(2004)
J Immunol
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
Christensen, J.R.2
Minaee, S.3
O'Neill, E.J.4
Barrat, F.J.5
Boonstra, A.6
-
82
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Y. Chen, V.K. Kuchroo, J. Inobe, D.A. Hafler, and H.L. Weiner Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis Science 265 1994 1237 1240
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
83
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
-
H.L. Weiner Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells Immunol Rev 182 2001 207 214
-
(2001)
Immunol Rev
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
84
-
-
20844432359
-
Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
-
C. Karagiannidis, M. Akdis, P. Holopainen, N.J. Woolley, G. Hense, and B. Ruckert Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma J Allergy Clin Immunol 114 2004 1425 1433
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 1425-1433
-
-
Karagiannidis, C.1
Akdis, M.2
Holopainen, P.3
Woolley, N.J.4
Hense, G.5
Ruckert, B.6
-
85
-
-
1642453559
-
Specialization in tolerance: Innate CD(4+)CD(25+) versus acquired TR1 and TH3 regulatory T cells
-
F. Cottrez, and H. Groux Specialization in tolerance: innate CD(4+)CD(25+) versus acquired TR1 and TH3 regulatory T cells Transplantation 77 suppl 2004 S12 S15
-
(2004)
Transplantation
, vol.77
, Issue.SUPPL.
-
-
Cottrez, F.1
Groux, H.2
-
86
-
-
0242412365
-
A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation
-
A. Foussat, F. Cottrez, V. Brun, N. Fournier, J.P. Breittmayer, and H. Groux A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation J Immunol 171 2003 5018 5026
-
(2003)
J Immunol
, vol.171
, pp. 5018-5026
-
-
Foussat, A.1
Cottrez, F.2
Brun, V.3
Fournier, N.4
Breittmayer, J.P.5
Groux, H.6
-
87
-
-
10744226674
-
Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes
-
L. Cosmi, F. Liotta, E. Lazzeri, M. Francalanci, R. Angeli, and B. Mazzinghi Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes Blood 102 2003 4107 4114
-
(2003)
Blood
, vol.102
, pp. 4107-4114
-
-
Cosmi, L.1
Liotta, F.2
Lazzeri, E.3
Francalanci, M.4
Angeli, R.5
Mazzinghi, B.6
-
88
-
-
4344675302
-
Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity
-
J.S. Manavalan, S. Kim-Schulze, L. Scotto, A.J. Naiyer, G. Vlad, and P.C. Colombo Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity Int Immunol 16 2004 1055 1068
-
(2004)
Int Immunol
, vol.16
, pp. 1055-1068
-
-
Manavalan, J.S.1
Kim-Schulze, S.2
Scotto, L.3
Naiyer, A.J.4
Vlad, G.5
Colombo, P.C.6
-
89
-
-
8644240281
-
Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation
-
E. Xystrakis, A.S. Dejean, I. Bernard, P. Druet, R. Liblau, and D. Gonzalez-Dunia Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation Blood 104 2004 3294 3301
-
(2004)
Blood
, vol.104
, pp. 3294-3301
-
-
Xystrakis, E.1
Dejean, A.S.2
Bernard, I.3
Druet, P.4
Liblau, R.5
Gonzalez-Dunia, D.6
-
90
-
-
20844457916
-
Rat CD8(+) FOXP3(+) T suppressor cells mediate tolerance to allogeneic heart transplants, inducing PIR-B in APC and rendering the graft invulnerable to rejection
-
J. Liu, Z. Liu, P. Witkowski, G. Vlad, J.S. Manavalan, and L. Scotto Rat CD8(+) FOXP3(+) T suppressor cells mediate tolerance to allogeneic heart transplants, inducing PIR-B in APC and rendering the graft invulnerable to rejection Transpl Immunol 13 2004 239 247
-
(2004)
Transpl Immunol
, vol.13
, pp. 239-247
-
-
Liu, J.1
Liu, Z.2
Witkowski, P.3
Vlad, G.4
Manavalan, J.S.5
Scotto, L.6
-
91
-
-
3042594506
-
Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy
-
M.R. Karlsson, J. Rugtveit, and P. Brandtzaeg Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy J Exp Med 199 2004 1679 1688
-
(2004)
J Exp Med
, vol.199
, pp. 1679-1688
-
-
Karlsson, M.R.1
Rugtveit, J.2
Brandtzaeg, P.3
-
92
-
-
1942531991
-
T regulatory cells in atopic dermatitis and subversion of their activity by superantigens
-
L.S. Ou, E. Goleva, C. Hall, and D.Y. Leung T regulatory cells in atopic dermatitis and subversion of their activity by superantigens J Allergy Clin Immunol 113 2004 756 763
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 756-763
-
-
Ou, L.S.1
Goleva, E.2
Hall, C.3
Leung, D.Y.4
-
93
-
-
0037504093
-
Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy
-
J.N. Francis, S.J. Till, and S.R. Durham Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy J Allergy Clin Immunol 111 2003 1255 1261
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 1255-1261
-
-
Francis, J.N.1
Till, S.J.2
Durham, S.R.3
-
94
-
-
0038363534
-
IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
-
M. Jutel, M. Akdis, F. Budak, C. Aebischer-Casaulta, M. Wrzyszcz, and K. Blaser IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy Eur J Immunol 33 2003 1205 1214
-
(2003)
Eur J Immunol
, vol.33
, pp. 1205-1214
-
-
Jutel, M.1
Akdis, M.2
Budak, F.3
Aebischer-Casaulta, C.4
Wrzyszcz, M.5
Blaser, K.6
-
95
-
-
2942685507
-
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
-
M. Akdis, J. Verhagen, A. Taylor, F. Karamloo, C. Karagiannidis, and R. Crameri Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells J Exp Med 199 2004 1567 1575
-
(2004)
J Exp Med
, vol.199
, pp. 1567-1575
-
-
Akdis, M.1
Verhagen, J.2
Taylor, A.3
Karamloo, F.4
Karagiannidis, C.5
Crameri, R.6
-
96
-
-
4344696812
-
Fluticasone propionate increases CD4CD25 T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism
-
X. Dao Nguyen, and D.S. Robinson Fluticasone propionate increases CD4CD25 T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism J Allergy Clin Immunol 114 2004 296 301
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 296-301
-
-
Dao Nguyen, X.1
Robinson, D.S.2
-
97
-
-
0036278230
-
Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells
-
C. Zuany-Amorim, E. Sawicka, C. Manlius, A. Le Moine, L.R. Brunet, and D.M. Kemeny Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells Nat Med 8 2002 625 629
-
(2002)
Nat Med
, vol.8
, pp. 625-629
-
-
Zuany-Amorim, C.1
Sawicka, E.2
Manlius, C.3
Le Moine, A.4
Brunet, L.R.5
Kemeny, D.M.6
-
98
-
-
0036681632
-
Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation
-
C. Zuany-Amorim, C. Manlius, A. Trifilieff, L.R. Brunet, G. Rook, and G. Bowen Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation J Immunol 169 2002 1492 1499
-
(2002)
J Immunol
, vol.169
, pp. 1492-1499
-
-
Zuany-Amorim, C.1
Manlius, C.2
Trifilieff, A.3
Brunet, L.R.4
Rook, G.5
Bowen, G.6
-
99
-
-
0037323748
-
Impact of Mycobacterium vaccae immunization on lung histopathology in a murine model of chronic asthma
-
C. Ozdemir, T. Akkoc, N.N. Bahceciler, D. Kucukercan, I.B. Barlan, and M.M. Basaran Impact of Mycobacterium vaccae immunization on lung histopathology in a murine model of chronic asthma Clin Exp Allergy 33 2003 266 270
-
(2003)
Clin Exp Allergy
, vol.33
, pp. 266-270
-
-
Ozdemir, C.1
Akkoc, T.2
Bahceciler, N.N.3
Kucukercan, D.4
Barlan, I.B.5
Basaran, M.M.6
-
100
-
-
0035094643
-
Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease
-
P.D. Arkwright, and T.J. David Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease J Allergy Clin Immunol 107 2001 531 534
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 531-534
-
-
Arkwright, P.D.1
David, T.J.2
-
101
-
-
12244290348
-
The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma
-
L. Camporota, A. Corkhill, H. Long, J. Lordan, L. Stanciu, and N. Tuckwell The effects of Mycobacterium vaccae on allergen-induced airway responses in atopic asthma Eur Respir J 21 2003 287 293
-
(2003)
Eur Respir J
, vol.21
, pp. 287-293
-
-
Camporota, L.1
Corkhill, A.2
Long, H.3
Lordan, J.4
Stanciu, L.5
Tuckwell, N.6
-
102
-
-
0347518970
-
Pilot study of the safety and effect of intranasal delipidated acid-treated Mycobacterium vaccae in adult asthma
-
P.M. Shirtcliffe, A. Goldkorn, M. Weatherall, P.L. Tan, and R. Beasley Pilot study of the safety and effect of intranasal delipidated acid-treated Mycobacterium vaccae in adult asthma Respirology 8 2003 497 503
-
(2003)
Respirology
, vol.8
, pp. 497-503
-
-
Shirtcliffe, P.M.1
Goldkorn, A.2
Weatherall, M.3
Tan, P.L.4
Beasley, R.5
-
103
-
-
0042074304
-
Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features
-
J.J. Smit, H. Van Loveren, M.O. Hoekstra, M.A. Schijf, G. Folkerts, and F.P. Nijkamp Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features Clin Exp Allergy 33 2003 1083 1089
-
(2003)
Clin Exp Allergy
, vol.33
, pp. 1083-1089
-
-
Smit, J.J.1
Van Loveren, H.2
Hoekstra, M.O.3
Schijf, M.A.4
Folkerts, G.5
Nijkamp, F.P.6
-
104
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
S. Akira, K. Takeda, and T. Kaisho Toll-like receptors: critical proteins linking innate and acquired immunity Nat Immunol 2 2001 675 680
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
105
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
I. Caramalho, T. Lopes-Carvalho, D. Ostler, S. Zelenay, M. Haury, and J. Demengeot Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide J Exp Med 197 2003 403 411
-
(2003)
J Exp Med
, vol.197
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
106
-
-
0242556891
-
Toll-like receptors: Balancing host resistance with immune tolerance
-
C. Pasare, and R. Medzhitov Toll-like receptors: balancing host resistance with immune tolerance Curr Opin Immunol 15 2003 677 682
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 677-682
-
-
Pasare, C.1
Medzhitov, R.2
-
107
-
-
3543097547
-
Suppressor T cells in human diseases
-
C. Baecher-Allan, and D.A. Hafler Suppressor T cells in human diseases J Exp Med 200 2004 273 276
-
(2004)
J Exp Med
, vol.200
, pp. 273-276
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
108
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
V. Viglietta, C. Baecher-Allan, H.L. Weiner, and D.A. Hafler Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis J Exp Med 199 2004 971 979
-
(2004)
J Exp Med
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
109
-
-
2442628376
-
Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II
-
M.A. Kriegel, T. Lohmann, C. Gabler, N. Blank, J.R. Kalden, and H.M. Lorenz Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II J Exp Med 199 2004 1285 1291
-
(2004)
J Exp Med
, vol.199
, pp. 1285-1291
-
-
Kriegel, M.A.1
Lohmann, T.2
Gabler, C.3
Blank, N.4
Kalden, J.R.5
Lorenz, H.M.6
-
110
-
-
11244291391
-
Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis
-
A. Balandina, S. Lecart, P. Dartevelle, A. Saoudi, and S. Berrih-Aknin Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis Blood 105 2005 735 741
-
(2005)
Blood
, vol.105
, pp. 735-741
-
-
Balandina, A.1
Lecart, S.2
Dartevelle, P.3
Saoudi, A.4
Berrih-Aknin, S.5
-
111
-
-
3543140687
-
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
-
M.R. Ehrenstein, J.G. Evans, A. Singh, S. Moore, G. Warnes, and D.A. Isenberg Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy J Exp Med 200 2004 277 285
-
(2004)
J Exp Med
, vol.200
, pp. 277-285
-
-
Ehrenstein, M.R.1
Evans, J.G.2
Singh, A.3
Moore, S.4
Warnes, G.5
Isenberg, D.A.6
-
112
-
-
0037261145
-
Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis
-
D. Cao, V. Malmstrom, C. Baecher-Allan, D. Hafler, L. Klareskog, and C. Trollmo Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis Eur J Immunol 33 2003 215 223
-
(2003)
Eur J Immunol
, vol.33
, pp. 215-223
-
-
Cao, D.1
Malmstrom, V.2
Baecher-Allan, C.3
Hafler, D.4
Klareskog, L.5
Trollmo, C.6
-
113
-
-
15244361536
-
CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
-
D. Cao, R. van Vollenhoven, L. Klareskog, C. Trollmo, and V. Malmstrom CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease Arthritis Res Ther 6 2004 R335 R346
-
(2004)
Arthritis Res Ther
, vol.6
-
-
Cao, D.1
Van Vollenhoven, R.2
Klareskog, L.3
Trollmo, C.4
Malmstrom, V.5
-
114
-
-
12144289938
-
Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis
-
B.J. Prakken, R. Samodal, T.D. Le, F. Giannoni, G.P. Yung, and J. Scavulli Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis Proc Natl Acad Sci U S A 101 2004 4228 4233
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4228-4233
-
-
Prakken, B.J.1
Samodal, R.2
Le, T.D.3
Giannoni, F.4
Yung, G.P.5
Scavulli, J.6
-
115
-
-
4043102582
-
Regulatory cells and infectious agents: Detentes cordiale and contraire
-
B.T. Rouse, and S. Suvas Regulatory cells and infectious agents: detentes cordiale and contraire J Immunol 173 2004 2211 2215
-
(2004)
J Immunol
, vol.173
, pp. 2211-2215
-
-
Rouse, B.T.1
Suvas, S.2
-
116
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
Y. Belkaid, and B.T. Rouse Natural regulatory T cells in infectious disease Nat Immunol 6 2005 353 360
-
(2005)
Nat Immunol
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
117
-
-
7044247947
-
An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
-
R. Cabrera, Z. Tu, Y. Xu, R.J. Firpi, H.R. Rosen, and C. Liu An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection Hepatology 40 2004 1062 1071
-
(2004)
Hepatology
, vol.40
, pp. 1062-1071
-
-
Cabrera, R.1
Tu, Z.2
Xu, Y.3
Firpi, R.J.4
Rosen, H.R.5
Liu, C.6
-
118
-
-
16244379546
-
Regulatory T cells and intestinal homeostasis
-
J.L. Coombes, N.J. Robinson, K.J. Maloy, H.H. Uhlig, and F. Powrie Regulatory T cells and intestinal homeostasis Immunol Rev 204 2005 184 194
-
(2005)
Immunol Rev
, vol.204
, pp. 184-194
-
-
Coombes, J.L.1
Robinson, N.J.2
Maloy, K.J.3
Uhlig, H.H.4
Powrie, F.5
-
119
-
-
1842455770
-
Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells
-
H. Hisaeda, Y. Maekawa, D. Iwakawa, H. Okada, K. Himeno, and K. Kishihara Escape of malaria parasites from host immunity requires CD4+ CD25+ regulatory T cells Nat Med 10 2004 29 30
-
(2004)
Nat Med
, vol.10
, pp. 29-30
-
-
Hisaeda, H.1
Maekawa, Y.2
Iwakawa, D.3
Okada, H.4
Himeno, K.5
Kishihara, K.6
-
120
-
-
18244370760
-
Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease
-
Y. Yamano, N. Takenouchi, H.C. Li, U. Tomaru, K. Yao, and C.W. Grant Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease J Clin Invest 115 2005 1361 1368
-
(2005)
J Clin Invest
, vol.115
, pp. 1361-1368
-
-
Yamano, Y.1
Takenouchi, N.2
Li, H.C.3
Tomaru, U.4
Yao, K.5
Grant, C.W.6
-
121
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
K. Oswald-Richter, S.M. Grill, N. Shariat, M. Leelawong, M.S. Sundrud, and D.W. Haas HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells PLoS Biol 2 2004 E198
-
(2004)
PLoS Biol
, vol.2
-
-
Oswald-Richter, K.1
Grill, S.M.2
Shariat, N.3
Leelawong, M.4
Sundrud, M.S.5
Haas, D.W.6
|