IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Nature Immunology

Volumn 8, Issue 9, 2007, Pages 967-974

  Zhou, Liang ^a   Ivanov, Ivaylo I ^a   Spolski, Rosanne ^b   Min, Roy ^a   Shenderov, Kevin ^a   Egawa, Takeshi ^a   Levy, David E ^a   Leonard, Warren J ^b   Littman, Dan R ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN 23; INTERLEUKIN 6; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; HELPER CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOBLOTTING; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-6; INTERLEUKINS; MICE; MICE, MUTANT STRAINS; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 34547188748     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1488     Document Type: Article

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