GATA-3 promotes Th2 responses through three different mechanisms: Induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

Cell Research

Volumn 16, Issue 1, 2006, Pages 3-10

  Zhu, Jinfang ^a   Yamane, Hidehiro ^a   Cote Sierra, Javier ^a   Guo, Liying ^a   Paul, William E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Cell expansion; GATA 3; Gfi 1; Stat5; Th2 cell differentiation; Transcription factors

Indexed keywords

CYTOKINE; DNA BINDING PROTEIN; GFI1 PROTEIN, MOUSE; INTERLEUKIN 2; INTERLEUKIN 4; IONOMYCIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; STAT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3;

ANIMAL; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; TRANSACTIVATION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; DNA-BINDING PROTEINS; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; INTERLEUKIN-2; INTERLEUKIN-4; IONOMYCIN; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TETRADECANOYLPHORBOL ACETATE; TH1 CELLS; TH2 CELLS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 31144460961     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7310002     Document Type: Review

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