Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: A new therapeutic approach for the treatment of inflammatory diseases

Current Pharmaceutical Design

Volumn 10, Issue 8, 2004, Pages 879-891

  Chen, Xi lin ^a   Kunsch, Charles ^a  

^a AtheroGenics Inc   (United States)

Author keywords

Antioxidant response element; Inflammation; Nrf2; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; ANTIRHEUMATIC AGENT; APOFERRITIN; CELL ADHESION MOLECULE; DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; FERRITIN; GLUCURONOSYLTRANSFERASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; GOLD SALT; HEME OXYGENASE 1; IBUPROFEN; INDOMETACIN; INTERCELLULAR ADHESION MOLECULE 1; METALLOTHIONEIN I; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFORAPHANE; SUPEROXIDE DISMUTASE; TERT BUTYLHYDROQUINONE; THIOREDOXIN; TRANSALDOLASE; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR NF E2; TRANSKETOLASE; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIOXIDANT ACTIVITY; ATHEROSCLEROSIS; CELL PROLIFERATION; CELL PROTECTION; CHRONIC INFLAMMATION; CLINICAL TRIAL; CYTOKINE PRODUCTION; DNA BINDING; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION; HUMAN; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANTIOXIDANTS; CYTOPROTECTION; DNA-BINDING PROTEINS; GENE THERAPY; HUMANS; INFLAMMATION; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 1642368362     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612043452901     Document Type: Review

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