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Volumn 72, Issue 4, 2007, Pages 799-809

Separating transrepression and transactivation: A distressing divorce for the glucocorticoid receptor?

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; CCAAT ENHANCER BINDING PROTEIN; CYCLIN D3; CYCLOOXYGENASE 2; DACTINOMYCIN; DEXAMETHASONE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 11; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA POLYMERASE II; RU 24858; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 34748920671     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.038794     Document Type: Short Survey
Times cited : (273)

References (175)
  • 1
    • 0028925985 scopus 로고
    • Corticosteroids increase secretory leukocyte protease inhibitor transcript levels in airway epithelial cells
    • Abbinante-Nissen JM, Simpson LG, and Leikauf GD (1995) Corticosteroids increase secretory leukocyte protease inhibitor transcript levels in airway epithelial cells. Am J Physiol 268:L601-L606.
    • (1995) Am J Physiol , vol.268
    • Abbinante-Nissen, J.M.1    Simpson, L.G.2    Leikauf, G.D.3
  • 3
    • 0346849703 scopus 로고    scopus 로고
    • Homodimerization of the glucocorticoid receptor is not essential for response element binding: Activation of the phenylethanolamine N-methyltransferase gene by dimerizationdefective mutants
    • Adams M, Meijer OC, Wang J, Bhargava A, and Pearce D (2003) Homodimerization of the glucocorticoid receptor is not essential for response element binding: activation of the phenylethanolamine N-methyltransferase gene by dimerizationdefective mutants. Mol Endocrinol 17:2583-2592.
    • (2003) Mol Endocrinol , vol.17 , pp. 2583-2592
    • Adams, M.1    Meijer, O.C.2    Wang, J.3    Bhargava, A.4    Pearce, D.5
  • 4
    • 26944472106 scopus 로고    scopus 로고
    • Glucocorticoids: Effects on gene transcription
    • Adcock IM, Ito K, and Barnes PJ (2004) Glucocorticoids: effects on gene transcription. Proc Am Thorac Soc 1:247-254.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 247-254
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 5
    • 0343618515 scopus 로고    scopus 로고
    • Cooperation among stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes
    • Aittomäki S, Pesu M, Groner B, Janne OA, Palvimo JJ, and Silvennoinen O (2000) Cooperation among stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes. J Immunol 164:5689-5697.
    • (2000) J Immunol , vol.164 , pp. 5689-5697
    • Aittomäki, S.1    Pesu, M.2    Groner, B.3    Janne, O.A.4    Palvimo, J.J.5    Silvennoinen, O.6
  • 6
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, and Karin M (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 8
    • 33744477341 scopus 로고    scopus 로고
    • How corticosteroids control inflammation: Quintiles prize lecture 2005
    • Barnes PJ (2006) How corticosteroids control inflammation: quintiles prize lecture 2005. Br J Pharmacol 148:245-254.
    • (2006) Br J Pharmacol , vol.148 , pp. 245-254
    • Barnes, P.J.1
  • 9
    • 0035253604 scopus 로고    scopus 로고
    • Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity
    • Belvisi MG, Wicks SL, Battram CH, Bottoms SE, Redford JE, Woodman P, Brown TJ, Webber SE, and Foster ML (2001) Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity. J Immunol 166:1975-1982.
    • (2001) J Immunol , vol.166 , pp. 1975-1982
    • Belvisi, M.G.1    Wicks, S.L.2    Battram, C.H.3    Bottoms, S.E.4    Redford, J.E.5    Woodman, P.6    Brown, T.J.7    Webber, S.E.8    Foster, M.L.9
  • 10
    • 1842556193 scopus 로고    scopus 로고
    • Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0
    • Bergmann MW, Staples KJ, Smith SJ, Barnes PJ, and Newton R (2004) Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0. Am J Respir Cell Mol Biol 30:555-563.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 555-563
    • Bergmann, M.W.1    Staples, K.J.2    Smith, S.J.3    Barnes, P.J.4    Newton, R.5
  • 11
    • 0037438590 scopus 로고    scopus 로고
    • Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: An anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10
    • Berrebi D, Bruscoli S, Cohen N, Foussat A, Migliorati G, Bouchet-Delbos L, Maillot MC, Portier A, Couderc J, Galanaud P, et al. (2003) Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. Blood 101:729-738.
    • (2003) Blood , vol.101 , pp. 729-738
    • Berrebi, D.1    Bruscoli, S.2    Cohen, N.3    Foussat, A.4    Migliorati, G.5    Bouchet-Delbos, L.6    Maillot, M.C.7    Portier, A.8    Couderc, J.9    Galanaud, P.10
  • 13
    • 14944350347 scopus 로고    scopus 로고
    • Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression
    • Bladh LG, Liden J, Dahlman-Wright K, Reimers M, Nilsson S, and Okret S (2005) Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression. Mol Pharmacol 67:815-826.
    • (2005) Mol Pharmacol , vol.67 , pp. 815-826
    • Bladh, L.G.1    Liden, J.2    Dahlman-Wright, K.3    Reimers, M.4    Nilsson, S.5    Okret, S.6
  • 15
    • 0031569536 scopus 로고    scopus 로고
    • Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun
    • Brostjan C, Anrather J, Csizmadia V, Natarajan G, and Winkler H (1997) Glucocorticoids inhibit E-selectin expression by targeting NF-kappaB and not ATF/c-Jun. J Immunol 158:3836-3844.
    • (1997) J Immunol , vol.158 , pp. 3836-3844
    • Brostjan, C.1    Anrather, J.2    Csizmadia, V.3    Natarajan, G.4    Winkler, H.5
  • 16
    • 0029778179 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of NFκB activity in endothelial cells does not involve induction of IκBα synthesis
    • Brostjan C, Anrather J, Csizmadia V, Stroka D, Soares M, Bach FH, and Winkler H (1996) Glucocorticoid-mediated repression of NFκB activity in endothelial cells does not involve induction of IκBα synthesis. J Biol Chem 271:19612-19616.
    • (1996) J Biol Chem , vol.271 , pp. 19612-19616
    • Brostjan, C.1    Anrather, J.2    Csizmadia, V.3    Stroka, D.4    Soares, M.5    Bach, F.H.6    Winkler, H.7
  • 17
    • 0028909667 scopus 로고    scopus 로고
    • Caldenhoven E, Liden J, Wissink S, van de SA, Raaijmakers J, Koenderman L, Okret S, Gustafsson JA, and van der Saag PT (1995) Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol Endocrinol 9:401-412.
    • Caldenhoven E, Liden J, Wissink S, van de SA, Raaijmakers J, Koenderman L, Okret S, Gustafsson JA, and van der Saag PT (1995) Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol Endocrinol 9:401-412.
  • 18
    • 33746217403 scopus 로고    scopus 로고
    • Catley MC, Sukkar MB, Chung KF, Jaffee B, Liao SM, Coyle AJ, Haddad e, Barnes PJ, and Newton R (2006) Validation of the anti-inflammatory properties of smallmolecule IB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle. Mol Pharmacol 70:697-705.
    • Catley MC, Sukkar MB, Chung KF, Jaffee B, Liao SM, Coyle AJ, Haddad e, Barnes PJ, and Newton R (2006) Validation of the anti-inflammatory properties of smallmolecule IB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle. Mol Pharmacol 70:697-705.
  • 19
    • 0031899361 scopus 로고    scopus 로고
    • Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
    • Cella N, Groner B, and Hynes NE (1998) Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells. Mol Cell Biol 18:1783-1792.
    • (1998) Mol Cell Biol , vol.18 , pp. 1783-1792
    • Cella, N.1    Groner, B.2    Hynes, N.E.3
  • 20
    • 0033593351 scopus 로고    scopus 로고
    • The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropinreleasing hormone distal negative glucocorticoid response element
    • Chandran UR, Warren BS, Baumann CT, Hager GL, and DeFranco DB (1999) The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropinreleasing hormone distal negative glucocorticoid response element. J Biol Chem 274:2372-2378.
    • (1999) J Biol Chem , vol.274 , pp. 2372-2378
    • Chandran, U.R.1    Warren, B.S.2    Baumann, C.T.3    Hager, G.L.4    DeFranco, D.B.5
  • 21
    • 0035015922 scopus 로고    scopus 로고
    • Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells
    • Chang MM, Juarez M, Hyde DM, and Wu R (2001) Mechanism of dexamethasone-mediated interleukin-8 gene suppression in cultured airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 280:L107- L115.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Chang, M.M.1    Juarez, M.2    Hyde, D.M.3    Wu, R.4
  • 22
    • 0035884932 scopus 로고    scopus 로고
    • Cutting edge: Altered pulmonary eosinophilic inflammation in mice deficient for Clara cell secretory 10-kDa Protein
    • Chen LC, Zhang Z, Myers AC, and Huang SK (2001) Cutting edge: altered pulmonary eosinophilic inflammation in mice deficient for Clara cell secretory 10-kDa Protein. J Immunol 167:3025-3028.
    • (2001) J Immunol , vol.167 , pp. 3025-3028
    • Chen, L.C.1    Zhang, Z.2    Myers, A.C.3    Huang, S.K.4
  • 23
    • 0036884621 scopus 로고    scopus 로고
    • Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages
    • Chen P, Li J, Barnes J, Kokkonen GC, Lee JC, and Liu Y (2002) Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J Immunol 169:6408-6416.
    • (2002) J Immunol , vol.169 , pp. 6408-6416
    • Chen, P.1    Li, J.2    Barnes, J.3    Kokkonen, G.C.4    Lee, J.C.5    Liu, Y.6
  • 24
    • 0034730644 scopus 로고    scopus 로고
    • Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptorinduced gene transcription
    • Chen S, Sarlis NJ, and Simons SS Jr (2000) Evidence for a common step in three different processes for modulating the kinetic properties of glucocorticoid receptorinduced gene transcription. J Biol Chem 275:30106-30117.
    • (2000) J Biol Chem , vol.275 , pp. 30106-30117
    • Chen, S.1    Sarlis, N.J.2    Simons Jr, S.S.3
  • 25
    • 33751099074 scopus 로고    scopus 로고
    • Analysis of the dissociated steroid, RU24858, does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids
    • Chivers JE, Gong W, King EM, Seybold J, Mak JC, Donnelly LE, Holden NS, and Newton R (2006) Analysis of the dissociated steroid, RU24858, does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids. Mol Pharmacol 70:2084-2095.
    • (2006) Mol Pharmacol , vol.70 , pp. 2084-2095
    • Chivers, J.E.1    Gong, W.2    King, E.M.3    Seybold, J.4    Mak, J.C.5    Donnelly, L.E.6    Holden, N.S.7    Newton, R.8
  • 26
    • 14644401720 scopus 로고    scopus 로고
    • Role of activation function domain-1, DNA binding, and coactivator GRIP1 in the expression of partial agonist activity of glucocorticoid receptor-antagonist complexes
    • Cho S, Blackford JA Jr, and Simons SS Jr (2005) Role of activation function domain-1, DNA binding, and coactivator GRIP1 in the expression of partial agonist activity of glucocorticoid receptor-antagonist complexes. Biochemistry 44:3547-3561.
    • (2005) Biochemistry , vol.44 , pp. 3547-3561
    • Cho, S.1    Blackford Jr, J.A.2    Simons Jr, S.S.3
  • 27
    • 0029918680 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation
    • Chu Y, Solski PA, Khosravi-Far R, Der CJ, and Kelly K (1996) The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J Biol Chem 271:6497-6501.
    • (1996) J Biol Chem , vol.271 , pp. 6497-6501
    • Chu, Y.1    Solski, P.A.2    Khosravi-Far, R.3    Der, C.J.4    Kelly, K.5
  • 28
    • 0041669330 scopus 로고    scopus 로고
    • MAP kinase phosphatase 1: A novel mediator of biological effects of glucocorticoids?
    • Clark AR (2003) MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids? J Endocrinol 178:5-12.
    • (2003) J Endocrinol , vol.178 , pp. 5-12
    • Clark, A.R.1
  • 30
    • 0025759019 scopus 로고
    • Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids
    • Dahlman-Wright K, Wright A, Gustafsson JA, and Carlstedt-Duke J (1991) Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids. J Biol Chem 266:3107-3112.
    • (1991) J Biol Chem , vol.266 , pp. 3107-3112
    • Dahlman-Wright, K.1    Wright, A.2    Gustafsson, J.A.3    Carlstedt-Duke, J.4
  • 31
    • 0348141449 scopus 로고
    • Glucocorticoid induction of the rat tryptophan oxygenase gene is mediated by two widely separated glucocorticoid-responsive elements
    • Danesch U, Gloss B, Schmid W, Schutz G, Schüle R, and Renkawitz R (1987) Glucocorticoid induction of the rat tryptophan oxygenase gene is mediated by two widely separated glucocorticoid-responsive elements. EMBO J 6:625-630.
    • (1987) EMBO J , vol.6 , pp. 625-630
    • Danesch, U.1    Gloss, B.2    Schmid, W.3    Schutz, G.4    Schüle, R.5    Renkawitz, R.6
  • 32
    • 0031459881 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation
    • De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, and Haegeman G (1997) Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. Proc Natl Acad Sci U S A 94:13504-13509.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13504-13509
    • De Bosscher, K.1    Schmitz, M.L.2    Vanden Berghe, W.3    Plaisance, S.4    Fiers, W.5    Haegeman, G.6
  • 34
    • 0035147033 scopus 로고    scopus 로고
    • Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators
    • De Bosscher K, Vanden Berghe W, and Haegeman G (2001) Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators. Mol Endocrinol 15:219-227.
    • (2001) Mol Endocrinol , vol.15 , pp. 219-227
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 35
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: Molecular mechanisms for gene repression
    • De Bosscher K, Vanden Berghe W, and Haegeman G (2003) The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr Rev 24:488-522.
    • (2003) Endocr Rev , vol.24 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 36
    • 0034636021 scopus 로고    scopus 로고
    • Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of P65 with the basal transcription machinery, irrespective of coactivator levels in the cell
    • De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, and Haegeman G (2000) Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of P65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proc Natl Acad Sci U S A 97:3919-3924.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3919-3924
    • De Bosscher, K.1    Vanden Berghe, W.2    Vermeulen, L.3    Plaisance, S.4    Boone, E.5    Haegeman, G.6
  • 38
    • 0024799086 scopus 로고
    • Glucocorticoid repression of proopiomelanocortin gene transcription
    • Drouin J, Sun YL, and Nemer M (1989a) Glucocorticoid repression of proopiomelanocortin gene transcription. J Steroid Biochem 34:63-69.
    • (1989) J Steroid Biochem , vol.34 , pp. 63-69
    • Drouin, J.1    Sun, Y.L.2    Nemer, M.3
  • 39
    • 0024388773 scopus 로고
    • Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription
    • Drouin J, Trifiro MA, Plante RK, Nemer M, Eriksson P, and Wrange O (1989b) Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol Cell Biol 9:5305-5314.
    • (1989) Mol Cell Biol , vol.9 , pp. 5305-5314
    • Drouin, J.1    Trifiro, M.A.2    Plante, R.K.3    Nemer, M.4    Eriksson, P.5    Wrange, O.6
  • 40
    • 21344450122 scopus 로고    scopus 로고
    • Eberhardt W, Kilz T, Akool e, Muller R, and Pfeilschifter J (2005) Dissociated glucocorticoids equipotently inhibit cytokine- and CAMP-induced matrix degrading proteases in rat mesangial cells. Biochem Pharmacol 70:433-445.
    • Eberhardt W, Kilz T, Akool e, Muller R, and Pfeilschifter J (2005) Dissociated glucocorticoids equipotently inhibit cytokine- and CAMP-induced matrix degrading proteases in rat mesangial cells. Biochem Pharmacol 70:433-445.
  • 41
    • 33845945174 scopus 로고    scopus 로고
    • The anti-inflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells
    • Eddleston J, Herschbach J, Wagelie-Steffen AL, Christiansen SC, and Zuraw BL (2007) The anti-inflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells. J Allergy Clin Immunol 119:115-122.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 115-122
    • Eddleston, J.1    Herschbach, J.2    Wagelie-Steffen, A.L.3    Christiansen, S.C.4    Zuraw, B.L.5
  • 42
    • 0035818924 scopus 로고    scopus 로고
    • Nonsteroidal selective glucocorticoid modulators: The effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4- trimethyl-1H-[1]benzopyrano[3,4-f]quinolines
    • Elmore SW, Coghlan MJ, Anderson DD, Pratt JK, Green BE, Wang AX, Stashko MA, Lin CW, Tyree CM, Miner JN, et al. (2001) Nonsteroidal selective glucocorticoid modulators: the effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4- trimethyl-1H-[1]benzopyrano[3,4-f]quinolines. J Med Chem 44:4481-4491.
    • (2001) J Med Chem , vol.44 , pp. 4481-4491
    • Elmore, S.W.1    Coghlan, M.J.2    Anderson, D.D.3    Pratt, J.K.4    Green, B.E.5    Wang, A.X.6    Stashko, M.A.7    Lin, C.W.8    Tyree, C.M.9    Miner, J.N.10
  • 44
    • 27744593012 scopus 로고    scopus 로고
    • The role of posttranscriptional regulation in chemokine gene expression in inflammation and allergy
    • Fan J, Heller NM, Gorospe M, Atasoy U, and Stellato C (2005) The role of posttranscriptional regulation in chemokine gene expression in inflammation and allergy. Eur Respir J 26:933-947.
    • (2005) Eur Respir J , vol.26 , pp. 933-947
    • Fan, J.1    Heller, N.M.2    Gorospe, M.3    Atasoy, U.4    Stellato, C.5
  • 45
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • Flower RJ and Rothwell NJ (1994) Lipocortin-1: cellular mechanisms and clinical relevance. Trends Pharmacol Sci 15:71-76.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 46
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits P38 MAPK and stress-activated protein kinase in U937 cells
    • Franklin CC and Kraft AS (1997) Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits P38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 272:16917-16923.
    • (1997) J Biol Chem , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 47
    • 0033515428 scopus 로고    scopus 로고
    • Increasing the complexity of coactivation in nuclear receptor signaling
    • Freedman LP (1999) Increasing the complexity of coactivation in nuclear receptor signaling. Cell 97:5-8.
    • (1999) Cell , vol.97 , pp. 5-8
    • Freedman, L.P.1
  • 48
    • 33845997764 scopus 로고    scopus 로고
    • MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium
    • Fürst R, Schroeder T, Eilken HM, Bubik MF, Kiemer AK, Zahler S, and Vollmar AM (2007) MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium. FASEB J 21:74-80.
    • (2007) FASEB J , vol.21 , pp. 74-80
    • Fürst, R.1    Schroeder, T.2    Eilken, H.M.3    Bubik, M.F.4    Kiemer, A.K.5    Zahler, S.6    Vollmar, A.M.7
  • 50
    • 9644307891 scopus 로고    scopus 로고
    • Glucocorticoid ligands specify different interactions with NF-kappaB by allosteric effects on the glucocorticoid receptor DNA binding domain
    • Garside H, Stevens A, Farrow S, Normand C, Houle B, Berry A, Maschera B, and Ray D (2004) Glucocorticoid ligands specify different interactions with NF-kappaB by allosteric effects on the glucocorticoid receptor DNA binding domain. J Biol Chem 279:50050-50059.
    • (2004) J Biol Chem , vol.279 , pp. 50050-50059
    • Garside, H.1    Stevens, A.2    Farrow, S.3    Normand, C.4    Houle, B.5    Berry, A.6    Maschera, B.7    Ray, D.8
  • 52
    • 0031013332 scopus 로고    scopus 로고
    • The glucocorticoidresponsive gene cascade. Activation of the rat arginase gene through induction of C/EBPβ
    • Gotoh T, Chowdhury S, Takiguchi M, and Mori M (1997) The glucocorticoidresponsive gene cascade. Activation of the rat arginase gene through induction of C/EBPβ. J Biol Chem 272:3694-3698.
    • (1997) J Biol Chem , vol.272 , pp. 3694-3698
    • Gotoh, T.1    Chowdhury, S.2    Takiguchi, M.3    Mori, M.4
  • 53
    • 0037192796 scopus 로고    scopus 로고
    • Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases
    • Graham TE, Prossnitz ER, and Dorin RI (2002) Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases. J Biol Chem 277:10876-10882.
    • (2002) J Biol Chem , vol.277 , pp. 10876-10882
    • Graham, T.E.1    Prossnitz, E.R.2    Dorin, R.I.3
  • 54
    • 0034044596 scopus 로고    scopus 로고
    • Post-transcriptional regulation of bradykinin B1 and B2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-: Modulation by dexamethasone
    • Haddad EB, Fox AJ, Rousell J, Burgess G, McIntyre P, Barnes PJ, and Chung KF (2000) Post-transcriptional regulation of bradykinin B1 and B2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-: modulation by dexamethasone. Mol Pharmacol 57:1123-1131.
    • (2000) Mol Pharmacol , vol.57 , pp. 1123-1131
    • Haddad, E.B.1    Fox, A.J.2    Rousell, J.3    Burgess, G.4    McIntyre, P.5    Barnes, P.J.6    Chung, K.F.7
  • 55
    • 0030789420 scopus 로고    scopus 로고
    • I kappaB alpha-independent downregulation of NF-kappab activity by glucocorticoid receptor
    • Heck S, Bender K, Kullmann M, Gottlicher M, Herrlich P, and Cato AC (1997) I kappaB alpha-independent downregulation of NF-kappab activity by glucocorticoid receptor. EMBO J 16:4698-4707.
    • (1997) EMBO J , vol.16 , pp. 4698-4707
    • Heck, S.1    Bender, K.2    Kullmann, M.3    Gottlicher, M.4    Herrlich, P.5    Cato, A.C.6
  • 56
    • 0027934108 scopus 로고
    • A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1
    • Heck S, Kullmann M, Gast A, Ponta H, Rahmsdorf HJ, Herrlich P, and Cato AC (1994) A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J 13:4087-4095.
    • (1994) EMBO J , vol.13 , pp. 4087-4095
    • Heck, S.1    Kullmann, M.2    Gast, A.3    Ponta, H.4    Rahmsdorf, H.J.5    Herrlich, P.6    Cato, A.C.7
  • 57
    • 14944347295 scopus 로고    scopus 로고
    • Dexamethasone up-regulates the inhibitory adaptor protein dok-1 and suppresses downstream activation of the mitogen-activated protein kinase pathway in antigen-stimulated RBL-2H3 mast cells
    • Hiragun T, Peng Z, and Beaven MA (2005) Dexamethasone up-regulates the inhibitory adaptor protein dok-1 and suppresses downstream activation of the mitogen-activated protein kinase pathway in antigen-stimulated RBL-2H3 mast cells. Mol Pharmacol 67:598-603.
    • (2005) Mol Pharmacol , vol.67 , pp. 598-603
    • Hiragun, T.1    Peng, Z.2    Beaven, M.A.3
  • 58
    • 33746933829 scopus 로고    scopus 로고
    • Cutting edge: Dexamethasone negatively regulates Syk in mast cells by up-regulating SRC-like adaptor protein
    • Hiragun T, Peng Z, and Beaven MA (2006) Cutting edge: dexamethasone negatively regulates Syk in mast cells by up-regulating SRC-like adaptor protein. J Immunol 177:2047-2050.
    • (2006) J Immunol , vol.177 , pp. 2047-2050
    • Hiragun, T.1    Peng, Z.2    Beaven, M.A.3
  • 59
    • 0036925189 scopus 로고    scopus 로고
    • The promoter context determines mutual repression or synergism between NF-B and the glucocorticoid receptor
    • Hofmann TG and Schmitz ML (2002) The promoter context determines mutual repression or synergism between NF-B and the glucocorticoid receptor. Biol Chem 383:1947-1951.
    • (2002) Biol Chem , vol.383 , pp. 1947-1951
    • Hofmann, T.G.1    Schmitz, M.L.2
  • 60
    • 33646113165 scopus 로고    scopus 로고
    • Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells
    • Humphrey EL, Williams JH, Davie MW, and Marshall MJ (2006) Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells. Bone 38:652-661.
    • (2006) Bone , vol.38 , pp. 652-661
    • Humphrey, E.L.1    Williams, J.H.2    Davie, M.W.3    Marshall, M.J.4
  • 61
    • 34249805700 scopus 로고    scopus 로고
    • Corticosteroid inhibition of growth-related oncogene protein-{alpha} via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells
    • Issa R, Xie S, Khorasani N, Sukkar M, Adcock IM, Lee KY, and Chung KF (2007) Corticosteroid inhibition of growth-related oncogene protein-{alpha} via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells. J Immunol 178:7366-7375.
    • (2007) J Immunol , vol.178 , pp. 7366-7375
    • Issa, R.1    Xie, S.2    Khorasani, N.3    Sukkar, M.4    Adcock, I.M.5    Lee, K.Y.6    Chung, K.F.7
  • 62
    • 0033821409 scopus 로고    scopus 로고
    • Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
    • Ito K, Barnes PJ, and Adcock IM (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20:6891-6903.
    • (2000) Mol Cell Biol , vol.20 , pp. 6891-6903
    • Ito, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 63
    • 0035839497 scopus 로고    scopus 로고
    • P65-activated histone acetyltransferase activity is repressed by glucocorticoids: Mifepristone fails to recruit HDAC2 to the P65-HAT complex
    • Ito K, Jazrawi E, Cosio B, Barnes PJ, and Adcock IM (2001) P65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the P65-HAT complex. J Biol Chem 276:30208-30215.
    • (2001) J Biol Chem , vol.276 , pp. 30208-30215
    • Ito, K.1    Jazrawi, E.2    Cosio, B.3    Barnes, P.J.4    Adcock, I.M.5
  • 64
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
    • Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, and Adcock IM (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 203:7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcock, I.M.7
  • 65
    • 13844270512 scopus 로고    scopus 로고
    • Inhibition of tristetraprolin expression by dexamethasone in activated macrophages
    • Jalonen U, Lahti A, Korhonen R, Kankaanranta H, and Moilanen E (2005) Inhibition of tristetraprolin expression by dexamethasone in activated macrophages. Biochem Pharmacol 69:733-740.
    • (2005) Biochem Pharmacol , vol.69 , pp. 733-740
    • Jalonen, U.1    Lahti, A.2    Korhonen, R.3    Kankaanranta, H.4    Moilanen, E.5
  • 66
    • 33748343189 scopus 로고    scopus 로고
    • The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils
    • Janka-Junttila M, Moilanen E, Hasala H, Zhang X, Adcock I, and Kankaanranta H (2006) The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils. J Inflamm (Lond) 3:10.
    • (2006) J Inflamm (Lond) , vol.3 , pp. 10
    • Janka-Junttila, M.1    Moilanen, E.2    Hasala, H.3    Zhang, X.4    Adcock, I.5    Kankaanranta, H.6
  • 67
    • 0023649643 scopus 로고
    • Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene
    • Jantzen HM, Strähle U, Gloss B, Stewart F, Schmid W, Boshart M, Miksicek R, and Schutz G (1987) Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene. Cell 49:29-38.
    • (1987) Cell , vol.49 , pp. 29-38
    • Jantzen, H.M.1    Strähle, U.2    Gloss, B.3    Stewart, F.4    Schmid, W.5    Boshart, M.6    Miksicek, R.7    Schutz, G.8
  • 68
    • 0025015647 scopus 로고
    • Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
    • Jonat C, Rahmsdorf HJ, Park KK, Cato AC, Gebel S, Ponta H, and Herrlich P (1990) Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62:1189-1204.
    • (1990) Cell , vol.62 , pp. 1189-1204
    • Jonat, C.1    Rahmsdorf, H.J.2    Park, K.K.3    Cato, A.C.4    Gebel, S.5    Ponta, H.6    Herrlich, P.7
  • 69
    • 33749322525 scopus 로고    scopus 로고
    • Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers
    • Kabotyanski EB, Huetter M, Xian W, Rijnkels M, and Rosen JM (2006) Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Mol Endocrinol 20:2355-2368.
    • (2006) Mol Endocrinol , vol.20 , pp. 2355-2368
    • Kabotyanski, E.B.1    Huetter, M.2    Xian, W.3    Rijnkels, M.4    Rosen, J.M.5
  • 71
    • 0037126628 scopus 로고    scopus 로고
    • Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
    • Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, and Cato AC (2001) Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J 20:7108-7116.
    • (2001) EMBO J , vol.20 , pp. 7108-7116
    • Kassel, O.1    Sancono, A.2    Kratzschmar, J.3    Kreft, B.4    Stassen, M.5    Cato, A.C.6
  • 72
    • 0038265311 scopus 로고    scopus 로고
    • The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism
    • Kauppi B, Jakob C, Farnegardh M, Yang J, Ahola H, Alarcon M, Calles K, Engstrom O, Harlan J, Muchmore S, et al. (2003) The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism. J Biol Chem 278:22748-22754.
    • (2003) J Biol Chem , vol.278 , pp. 22748-22754
    • Kauppi, B.1    Jakob, C.2    Farnegardh, M.3    Yang, J.4    Ahola, H.5    Alarcon, M.6    Calles, K.7    Engstrom, O.8    Harlan, J.9    Muchmore, S.10
  • 73
    • 0032488810 scopus 로고    scopus 로고
    • Dexamethasone rapidly induces a novel Ras superfamily member-related gene in Att-20 Cells
    • Kemppainen RJ and Behrend EN (1998) Dexamethasone rapidly induces a novel Ras superfamily member-related gene in Att-20 Cells. J Biol Chem 273:3129-3131.
    • (1998) J Biol Chem , vol.273 , pp. 3129-3131
    • Kemppainen, R.J.1    Behrend, E.N.2
  • 74
    • 0023906367 scopus 로고
    • Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms
    • Kern JA, Lamb RJ, Reed JC, Daniele RP, and Nowell PC (1988) Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanisms. J Clin Invest 81:237-244.
    • (1988) J Clin Invest , vol.81 , pp. 237-244
    • Kern, J.A.1    Lamb, R.J.2    Reed, J.C.3    Daniele, R.P.4    Nowell, P.C.5
  • 75
    • 0030060927 scopus 로고    scopus 로고
    • Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-B
    • Kleinert H, Euchenhofer C, Ihrig-Biedert I, and Forstermann U (1996) Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-B. Mol Pharmacol 49:15-21.
    • (1996) Mol Pharmacol , vol.49 , pp. 15-21
    • Kleinert, H.1    Euchenhofer, C.2    Ihrig-Biedert, I.3    Forstermann, U.4
  • 76
    • 0026579203 scopus 로고
    • Interference between pathway-specific transcription factors: Glucocorticoids antagonize phorbol esterinduced AP-1 activity without altering AP-1 site occupation in vivo
    • König H, Ponta H, Rahmsdorf HJ, and Herrlich P (1992) Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol esterinduced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J 11:2241-2246.
    • (1992) EMBO J , vol.11 , pp. 2241-2246
    • König, H.1    Ponta, H.2    Rahmsdorf, H.J.3    Herrlich, P.4
  • 77
    • 0030069606 scopus 로고    scopus 로고
    • The role of Stat and C/EBP transcription factors in the synergistic activation of rat serine protease inhibitor-3 gene by interleukin-6 and dexamethasone
    • Kordula T and Travis J (1996) The role of Stat and C/EBP transcription factors in the synergistic activation of rat serine protease inhibitor-3 gene by interleukin-6 and dexamethasone. Biochem J 313:1019-1027.
    • (1996) Biochem J , vol.313 , pp. 1019-1027
    • Kordula, T.1    Travis, J.2
  • 78
    • 0036765329 scopus 로고    scopus 로고
    • Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages
    • Korhonen R, Lahti A, Hamalainen M, Kankaanranta H, and Moilanen E (2002) Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages. Mol Pharmacol 62:698-704.
    • (2002) Mol Pharmacol , vol.62 , pp. 698-704
    • Korhonen, R.1    Lahti, A.2    Hamalainen, M.3    Kankaanranta, H.4    Moilanen, E.5
  • 79
    • 0033848995 scopus 로고    scopus 로고
    • Effects of glucocorticoids on tumor necrosis factor alpha-dependent activation of nuclear factor kappaB and expression of the intercellular adhesion molecule 1 gene in osteoblast-like ROS17/2.8 Cells
    • Kurokouchi K, Kambe F, Kikumori T, Sakai T, Sarkar D, Ishiguro N, Iwata H, and Seo H (2000) Effects of glucocorticoids on tumor necrosis factor alpha-dependent activation of nuclear factor kappaB and expression of the intercellular adhesion molecule 1 gene in osteoblast-like ROS17/2.8 Cells. J Bone Miner Res 15:1707-1715.
    • (2000) J Bone Miner Res , vol.15 , pp. 1707-1715
    • Kurokouchi, K.1    Kambe, F.2    Kikumori, T.3    Sakai, T.4    Sarkar, D.5    Ishiguro, N.6    Iwata, H.7    Seo, H.8
  • 80
    • 0033049125 scopus 로고    scopus 로고
    • Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
    • Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, and Blackshear PJ (1999) Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol 19:4311-4323.
    • (1999) Mol Cell Biol , vol.19 , pp. 4311-4323
    • Lai, W.S.1    Carballo, E.2    Strum, J.R.3    Kennington, E.A.4    Phillips, R.S.5    Blackshear, P.J.6
  • 81
    • 0036841288 scopus 로고    scopus 로고
    • Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK P38
    • Lasa M, Abraham SM, Boucheron C, Saklatvala J, and Clark AR (2002) Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK P38. Mol Cell Biol 22:7802-7811.
    • (2002) Mol Cell Biol , vol.22 , pp. 7802-7811
    • Lasa, M.1    Abraham, S.M.2    Boucheron, C.3    Saklatvala, J.4    Clark, A.R.5
  • 82
    • 0035138742 scopus 로고    scopus 로고
    • Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase P38
    • Lasa M, Brook M, Saklatvala J, and Clark AR (2001) Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase P38. Mol Cell Biol 21:771-780.
    • (2001) Mol Cell Biol , vol.21 , pp. 771-780
    • Lasa, M.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 83
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase P38 signaling cascade
    • Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, and Clark AR (2000) Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase P38 signaling cascade. Mol Cell Biol 20:4265-4274.
    • (2000) Mol Cell Biol , vol.20 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 85
    • 0000693107 scopus 로고
    • Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA
    • Lee SW, Tsou AP, Chan H, Thomas J, Petrie K, Eugui EM, and Allison AC (1988) Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA. Proc Natl Acad Sci U S A 85:1204-1208.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 1204-1208
    • Lee, S.W.1    Tsou, A.P.2    Chan, H.3    Thomas, J.4    Petrie, K.5    Eugui, E.M.6    Allison, A.C.7
  • 86
    • 0142091544 scopus 로고    scopus 로고
    • STAT3-dependent enhanceosome assembly and disassembly: Synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene
    • Lerner L, Henriksen MA, Zhang X, and Darnell JE Jr (2003) STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene. Genes Dev 17:2564-2577.
    • (2003) Genes Dev , vol.17 , pp. 2564-2577
    • Lerner, L.1    Henriksen, M.A.2    Zhang, X.3    Darnell Jr, J.E.4
  • 87
    • 0030824266 scopus 로고    scopus 로고
    • A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation
    • Liden J, Delaunay F, Rafter I, Gustafsson J, and Okret S (1997) A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation. J Biol Chem 272:21467-21472.
    • (1997) J Biol Chem , vol.272 , pp. 21467-21472
    • Liden, J.1    Delaunay, F.2    Rafter, I.3    Gustafsson, J.4    Okret, S.5
  • 88
    • 0028924419 scopus 로고
    • Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation
    • Liu Y, Gorospe M, Yang C, and Holbrook NJ (1995) Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 270:8377-8380.
    • (1995) J Biol Chem , vol.270 , pp. 8377-8380
    • Liu, Y.1    Gorospe, M.2    Yang, C.3    Holbrook, N.J.4
  • 90
    • 18244381020 scopus 로고    scopus 로고
    • The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression
    • Luecke HF and Yamamoto KR (2005) The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression. Genes Dev 19:1116-1127.
    • (2005) Genes Dev , vol.19 , pp. 1116-1127
    • Luecke, H.F.1    Yamamoto, K.R.2
  • 91
    • 15444376898 scopus 로고    scopus 로고
    • Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor
    • Martens C, Bilodeau S, Maira M, Gauthier Y, and Drouin J (2005) Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor. Mol Endocrinol 19:885-897.
    • (2005) Mol Endocrinol , vol.19 , pp. 885-897
    • Martens, C.1    Bilodeau, S.2    Maira, M.3    Gauthier, Y.4    Drouin, J.5
  • 92
    • 0031916865 scopus 로고    scopus 로고
    • Cross-talk between nuclear factor-kappa B and the steroid hormone receptors: Mechanisms of mutual antagonism
    • McKay LI, and Cidlowski JA (1998) Cross-talk between nuclear factor-kappa B and the steroid hormone receptors: mechanisms of mutual antagonism. Mol Endocrinol 12:45-56.
    • (1998) Mol Endocrinol , vol.12 , pp. 45-56
    • McKay, L.I.1    Cidlowski, J.A.2
  • 93
    • 0034464826 scopus 로고    scopus 로고
    • CBP (CREB binding protein) integrates NFkappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism
    • McKay LI, and Cidlowski JA (2000) CBP (CREB binding protein) integrates NFkappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism. Mol Endocrinol 14:1222-1234.
    • (2000) Mol Endocrinol , vol.14 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 94
    • 0036284103 scopus 로고    scopus 로고
    • Minireview: Nuclear receptor coactivators-an update
    • McKenna NJ, and O'Malley BW (2002) Minireview: nuclear receptor coactivators-an update. Endocrinology 143:2461-2465.
    • (2002) Endocrinology , vol.143 , pp. 2461-2465
    • McKenna, N.J.1    O'Malley, B.W.2
  • 96
    • 0030666901 scopus 로고    scopus 로고
    • A weak TATA box is a prerequisite for glucocorticoid-dependent repression of the osteocalcin gene
    • Meyer T, Carlstedt-Duke J, and Starr DB (1997) A weak TATA box is a prerequisite for glucocorticoid-dependent repression of the osteocalcin gene. J Biol Chem 272:30709-30714.
    • (1997) J Biol Chem , vol.272 , pp. 30709-30714
    • Meyer, T.1    Carlstedt-Duke, J.2    Starr, D.B.3
  • 97
    • 0032429910 scopus 로고    scopus 로고
    • Glucocorticoids inhibit IL-4 and mitogen-induced IL-4R alpha chain expression by different posttranscriptional mechanisms
    • Mozo L, Gayo A, Suarez A, Rivas D, Zamorano J, and Gutierrez C (1998) Glucocorticoids inhibit IL-4 and mitogen-induced IL-4R alpha chain expression by different posttranscriptional mechanisms. J Allergy Clin Immunol 102:968-976.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 968-976
    • Mozo, L.1    Gayo, A.2    Suarez, A.3    Rivas, D.4    Zamorano, J.5    Gutierrez, C.6
  • 98
    • 0035800872 scopus 로고    scopus 로고
    • Inhibition of AP-1 by the glucocorticoidinducible protein GILZ
    • Mittelstadt PR and Ashwell JD (2001) Inhibition of AP-1 by the glucocorticoidinducible protein GILZ. J Biol Chem 276:29603-29610.
    • (2001) J Biol Chem , vol.276 , pp. 29603-29610
    • Mittelstadt, P.R.1    Ashwell, J.D.2
  • 99
    • 0028305712 scopus 로고
    • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression
    • Mukaida N, Morita M, Ishikawa Y, Rice N, Okamoto S, Kasahara T, and Matsushima K (1994) Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-κB is target for glucocorticoid-mediated interleukin 8 gene repression. J Biol Chem 269:13289-13295.
    • (1994) J Biol Chem , vol.269 , pp. 13289-13295
    • Mukaida, N.1    Morita, M.2    Ishikawa, Y.3    Rice, N.4    Okamoto, S.5    Kasahara, T.6    Matsushima, K.7
  • 100
    • 0034808097 scopus 로고    scopus 로고
    • Differential interactions of specific nuclear factor I isoforms with the glucocorticoid receptor and STAT5 in the cooperative regulation of WAP gene transcription
    • Mukhopadhyay SS, Wyszomierski SL, Gronostajski RM, and Rosen JM (2001) Differential interactions of specific nuclear factor I isoforms with the glucocorticoid receptor and STAT5 in the cooperative regulation of WAP gene transcription. Mol Cell Biol 21:6859-6869.
    • (2001) Mol Cell Biol , vol.21 , pp. 6859-6869
    • Mukhopadhyay, S.S.1    Wyszomierski, S.L.2    Gronostajski, R.M.3    Rosen, J.M.4
  • 102
    • 0034130914 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action: What is important?
    • Newton R (2000) Molecular mechanisms of glucocorticoid action: what is important? Thorax 55:603-613.
    • (2000) Thorax , vol.55 , pp. 603-613
    • Newton, R.1
  • 103
    • 0032523897 scopus 로고    scopus 로고
    • Effect of dexamethasone on interleukin-1beta-(IL-1beta)- induced nuclear factor-kappab (NF-kappab) and kappab-dependent transcription in epithelial cells
    • Newton R, Hart LA, Stevens DA, Bergmann M, Donnelly LE, Adcock IM, and Barnes PJ (1998a) Effect of dexamethasone on interleukin-1beta-(IL-1beta)- induced nuclear factor-kappab (NF-kappab) and kappab-dependent transcription in epithelial cells. Eur J Biochem 254:81-89.
    • (1998) Eur J Biochem , vol.254 , pp. 81-89
    • Newton, R.1    Hart, L.A.2    Stevens, D.A.3    Bergmann, M.4    Donnelly, L.E.5    Adcock, I.M.6    Barnes, P.J.7
  • 104
    • 0037255931 scopus 로고    scopus 로고
    • Inhibitors of P38 mitogen-activated protein kinase: Potential as anti-Inflammatory Agents in Asthma?
    • Newton R and Holden N (2003) Inhibitors of P38 mitogen-activated protein kinase: potential as anti-Inflammatory Agents in Asthma? BioDrugs 17:113-129.
    • (2003) BioDrugs , vol.17 , pp. 113-129
    • Newton, R.1    Holden, N.2
  • 105
    • 0033610923 scopus 로고    scopus 로고
    • Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA
    • Newton R, Seybold J, Kuitert LM, Bergmann M, and Barnes PJ (1998b) Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. J Biol Chem 273:32312-32321.
    • (1998) J Biol Chem , vol.273 , pp. 32312-32321
    • Newton, R.1    Seybold, J.2    Kuitert, L.M.3    Bergmann, M.4    Barnes, P.J.5
  • 106
    • 33645807174 scopus 로고    scopus 로고
    • Dexamethasone-induced ras protein 1 negatively regulates protein kinase c delta: Implications for adenylyl cyclase 2 signaling
    • Nguyen CH and Watts VJ (2006) Dexamethasone-induced ras protein 1 negatively regulates protein kinase c delta: implications for adenylyl cyclase 2 signaling. Mol Pharmacol 69:1763-1771.
    • (2006) Mol Pharmacol , vol.69 , pp. 1763-1771
    • Nguyen, C.H.1    Watts, V.J.2
  • 107
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxyterminal domain
    • Nissen RM and Yamamoto KR (2000) The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxyterminal domain. Genes Dev 14:2314-2329.
    • (2000) Genes Dev , vol.14 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 108
    • 0030052429 scopus 로고    scopus 로고
    • Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/Gro, a member of the interleukin-8 family, through impairment of NF-kappa B activation
    • Ohtsuka T, Kubota A, Hirano T, Watanabe K, Yoshida H, Tsurufuji M, Iizuka Y, Konishi K, and Tsurufuji S (1996) Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/Gro, a member of the interleukin-8 family, through impairment of NF-kappa B activation. J Biol Chem 271:1651-1659.
    • (1996) J Biol Chem , vol.271 , pp. 1651-1659
    • Ohtsuka, T.1    Kubota, A.2    Hirano, T.3    Watanabe, K.4    Yoshida, H.5    Tsurufuji, M.6    Iizuka, Y.7    Konishi, K.8    Tsurufuji, S.9
  • 109
    • 0032515034 scopus 로고    scopus 로고
    • Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites
    • Pearce D, Matsui W, Miner JN, and Yamamoto KR (1998) Glucocorticoid receptor transcriptional activity determined by spacing of receptor and nonreceptor DNA sites. J Biol Chem 273:30081-30085.
    • (1998) J Biol Chem , vol.273 , pp. 30081-30085
    • Pearce, D.1    Matsui, W.2    Miner, J.N.3    Yamamoto, K.R.4
  • 110
    • 0027394555 scopus 로고
    • Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element
    • Pearce D and Yamamoto KR (1993) Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science 259:1161-1165.
    • (1993) Science , vol.259 , pp. 1161-1165
    • Pearce, D.1    Yamamoto, K.R.2
  • 111
    • 0026100340 scopus 로고
    • The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids
    • Peppel K, Vinci JM, and Baglioni C (1991) The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids. J Exp Med 173:349-355.
    • (1991) J Exp Med , vol.173 , pp. 349-355
    • Peppel, K.1    Vinci, J.M.2    Baglioni, C.3
  • 112
    • 0037226583 scopus 로고    scopus 로고
    • Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells
    • Planey SL, Abrams MT, Robertson NM, and Litwack G (2003) Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells. Cancer Res 63:172-178.
    • (2003) Cancer Res , vol.63 , pp. 172-178
    • Planey, S.L.1    Abrams, M.T.2    Robertson, N.M.3    Litwack, G.4
  • 113
    • 0032863156 scopus 로고    scopus 로고
    • Identification of a novel dexamethasone-sensitive RNA-destabilizing region on rat monocyte chemoattractant protein 1 mRNA
    • Poon M, Liu B, and Taubman MB (1999) Identification of a novel dexamethasone-sensitive RNA-destabilizing region on rat monocyte chemoattractant protein 1 mRNA. Mol Cell Biol 19:6471-6478.
    • (1999) Mol Cell Biol , vol.19 , pp. 6471-6478
    • Poon, M.1    Liu, B.2    Taubman, M.B.3
  • 114
    • 2442537231 scopus 로고    scopus 로고
    • Role of Hsp90 and the Hsp90-binding immunophilins in signalling protein movement
    • Pratt WB, Galigniana MD, Harrell JM, and DeFranco DB (2004) Role of Hsp90 and the Hsp90-binding immunophilins in signalling protein movement. Cell Signal 16:857-872.
    • (2004) Cell Signal , vol.16 , pp. 857-872
    • Pratt, W.B.1    Galigniana, M.D.2    Harrell, J.M.3    DeFranco, D.B.4
  • 115
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the P65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
    • Ray A and Prefontaine KE (1994) Physical association and functional antagonism between the P65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci U S A 91:752-756.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 116
    • 0030678464 scopus 로고    scopus 로고
    • Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids
    • Ray KP, Farrow S, Daly M, Talabot F, and Searle N (1997) Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids. Biochem J 328:707-715.
    • (1997) Biochem J , vol.328 , pp. 707-715
    • Ray, K.P.1    Farrow, S.2    Daly, M.3    Talabot, F.4    Searle, N.5
  • 117
    • 0028179247 scopus 로고
    • The type II "receptor" as a decoy target for interleukin 1 in polymorphonuclear leukocytes: Characterization of induction by dexamethasone and ligand binding properties of the released decoy receptor
    • Re F, Muzio M, De Rossi M, Polentarutti N, Giri JG, Mantovani A, and Colotta F (1994) The type II "receptor" as a decoy target for interleukin 1 in polymorphonuclear leukocytes: characterization of induction by dexamethasone and ligand binding properties of the released decoy receptor. J Exp Med 179:739-743.
    • (1994) J Exp Med , vol.179 , pp. 739-743
    • Re, F.1    Muzio, M.2    De Rossi, M.3    Polentarutti, N.4    Giri, J.G.5    Mantovani, A.6    Colotta, F.7
  • 120
    • 0028808720 scopus 로고
    • Glucocorticoid regulation of cyclin D3 gene transcription and mRNA stability in lymphoid cells
    • Reisman D and Thompson EA (1995) Glucocorticoid regulation of cyclin D3 gene transcription and mRNA stability in lymphoid cells. Mol Endocrinol 9:1500-1509.
    • (1995) Mol Endocrinol , vol.9 , pp. 1500-1509
    • Reisman, D.1    Thompson, E.A.2
  • 121
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids-new mechanisms for old drugs
    • Rhen T and Cidlowski JA (2005) Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353:1711-1723.
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 122
    • 0029809863 scopus 로고    scopus 로고
    • Down-regulation of cytokine-induced cyclooxygenase-2 transcript isoforms by dexamethasone: Evidence for post-transcriptional regulation
    • Ristimaki A, Narko K, and Hla T (1996) Down-regulation of cytokine-induced cyclooxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem J 318:325-331.
    • (1996) Biochem J , vol.318 , pp. 325-331
    • Ristimaki, A.1    Narko, K.2    Hla, T.3
  • 123
    • 0037168648 scopus 로고    scopus 로고
    • Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts
    • Rogatsky I, Luecke HF, Leitman DC, and Yamamoto KR (2002) Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts. Proc Natl Acad Sci U S A 99:16701-16706.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16701-16706
    • Rogatsky, I.1    Luecke, H.F.2    Leitman, D.C.3    Yamamoto, K.R.4
  • 125
    • 0035502975 scopus 로고    scopus 로고
    • Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones
    • Rogatsky I, Zarember KA, and Yamamoto KR (2001) Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. EMBO J 20:6071-6083.
    • (2001) EMBO J , vol.20 , pp. 6071-6083
    • Rogatsky, I.1    Zarember, K.A.2    Yamamoto, K.R.3
  • 126
    • 0024080921 scopus 로고
    • Hormone-mediated repression: A negative glucocorticoid response element from the bovine prolactin gene
    • Sakai DD, Helms S, Carlstedt-Duke J, Gustafsson JA, Rottman FM, and Yamamoto KR (1988) Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. Genes Dev 2:1144-1154.
    • (1988) Genes Dev , vol.2 , pp. 1144-1154
    • Sakai, D.D.1    Helms, S.2    Carlstedt-Duke, J.3    Gustafsson, J.A.4    Rottman, F.M.5    Yamamoto, K.R.6
  • 127
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • Schäcke H, Docke WD, and Asadullah K (2002) Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 96:23-43.
    • (2002) Pharmacol Ther , vol.96 , pp. 23-43
    • Schäcke, H.1    Docke, W.D.2    Asadullah, K.3
  • 128
    • 0347719371 scopus 로고    scopus 로고
    • Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
    • Schäcke H, Schottelius A, Docke WD, Strehlke P, Jaroch S, Schmees N, Rehwinkel H, Hennekes H, and Asadullah K (2004) Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects. Proc Natl Acad Sci U S A 101:227-232.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 227-232
    • Schäcke, H.1    Schottelius, A.2    Docke, W.D.3    Strehlke, P.4    Jaroch, S.5    Schmees, N.6    Rehwinkel, H.7    Hennekes, H.8    Asadullah, K.9
  • 129
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, and Baldwin AS Jr (1995a) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr, A.S.4
  • 130
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, and Baldwin AS Jr (1995b) Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol Cell Biol 15:943-953.
    • (1995) Mol Cell Biol , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin Jr, A.S.5
  • 131
    • 0024208947 scopus 로고
    • Many transcription factors interact synergistically with steroid receptors
    • Schüle R, Muller M, Kaltschmidt C, and Renkawitz R (1988) Many transcription factors interact synergistically with steroid receptors. Science 242:1418-1420.
    • (1988) Science , vol.242 , pp. 1418-1420
    • Schüle, R.1    Muller, M.2    Kaltschmidt, C.3    Renkawitz, R.4
  • 133
    • 4544343929 scopus 로고    scopus 로고
    • Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands
    • Shah N and Scanlan TS (2004) Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands. Bioorg Med Chem Lett 14:5199-5203.
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 5199-5203
    • Shah, N.1    Scanlan, T.S.2
  • 134
    • 0032491483 scopus 로고    scopus 로고
    • Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1
    • Sheppard KA, Phelps KM, Williams AJ, Thanos D, Glass CK, Rosenfeld MG, Gerritsen ME, and Collins T (1998) Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J Biol Chem 273:29291-29294.
    • (1998) J Biol Chem , vol.273 , pp. 29291-29294
    • Sheppard, K.A.1    Phelps, K.M.2    Williams, A.J.3    Thanos, D.4    Glass, C.K.5    Rosenfeld, M.G.6    Gerritsen, M.E.7    Collins, T.8
  • 135
    • 0033026004 scopus 로고    scopus 로고
    • Activation of nuclear factor kappaB by nitric oxide in rat striatal neurones: Differential inhibition of the P50 and P65 subunits by dexamethasone
    • Simpson CS and Morris BJ (1999) Activation of nuclear factor kappaB by nitric oxide in rat striatal neurones: differential inhibition of the P50 and P65 subunits by dexamethasone. J Neurochem 73:353-361.
    • (1999) J Neurochem , vol.73 , pp. 353-361
    • Simpson, C.S.1    Morris, B.J.2
  • 136
    • 0035844140 scopus 로고    scopus 로고
    • Distinct binding determinants for ERK2/P38α and JNK Map kinases mediate catalytic activation and substrate selectivity of Map kinase phosphatase-1
    • Slack DN, Seternes OM, Gabrielsen M, and Keyse SM (2001) Distinct binding determinants for ERK2/P38α and JNK Map kinases mediate catalytic activation and substrate selectivity of Map kinase phosphatase-1. J Biol Chem 276:16491-16500.
    • (2001) J Biol Chem , vol.276 , pp. 16491-16500
    • Slack, D.N.1    Seternes, O.M.2    Gabrielsen, M.3    Keyse, S.M.4
  • 137
    • 33845218654 scopus 로고    scopus 로고
    • Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling
    • Smoak K and Cidlowski JA (2006) Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling. Mol Cell Biol 26:9126-9135.
    • (2006) Mol Cell Biol , vol.26 , pp. 9126-9135
    • Smoak, K.1    Cidlowski, J.A.2
  • 138
    • 34347324118 scopus 로고    scopus 로고
    • Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor
    • So AY, Chaivorapol C, Bolton EC, Li H, and Yamamoto KR (2007) Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor. PLoS Genet 3:e94.
    • (2007) PLoS Genet , vol.3
    • So, A.Y.1    Chaivorapol, C.2    Bolton, E.C.3    Li, H.4    Yamamoto, K.R.5
  • 139
    • 0042769826 scopus 로고    scopus 로고
    • Evidence for posttranscriptional regulation of interleukin-5 by dexamethasone
    • Staples KJ, Bergmann MW, Barnes PJ, and Newton R (2003) Evidence for posttranscriptional regulation of interleukin-5 by dexamethasone. Immunology 109:527-535.
    • (2003) Immunology , vol.109 , pp. 527-535
    • Staples, K.J.1    Bergmann, M.W.2    Barnes, P.J.3    Newton, R.4
  • 140
    • 26944440532 scopus 로고    scopus 로고
    • Post-transcriptional and nongenomic effects of glucocorticoids
    • Stellato C (2004) Post-transcriptional and nongenomic effects of glucocorticoids. Proc Am Thorac Soc 1:255-263.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 255-263
    • Stellato, C.1
  • 141
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between stat5 and the glucocorticoid receptor
    • Stöcklin E, Wissler M, Gouilleux F, and Groner B (1996) Functional interactions between stat5 and the glucocorticoid receptor. Nature 383:726-728.
    • (1996) Nature , vol.383 , pp. 726-728
    • Stöcklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 142
    • 0242490975 scopus 로고
    • Synergistic action of the glucocorticoid receptor with transcription factors
    • Strähle U, Schmid W, and Schutz G (1988) Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J 7:3389-3395.
    • (1988) EMBO J , vol.7 , pp. 3389-3395
    • Strähle, U.1    Schmid, W.2    Schutz, G.3
  • 143
    • 0025804498 scopus 로고
    • The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: A potential mechanism for negative regulation
    • Strömstedt PE, Poellinger L, Gustafsson JA, and Carlstedt-Duke J (1991) The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation. Mol Cell Biol 11:3379-3383.
    • (1991) Mol Cell Biol , vol.11 , pp. 3379-3383
    • Strömstedt, P.E.1    Poellinger, L.2    Gustafsson, J.A.3    Carlstedt-Duke, J.4
  • 144
    • 0032483406 scopus 로고    scopus 로고
    • Glucocorticoids repress transcription from a negative glucocorticoid response element recognized by two homeodomaincontaining proteins, Pbx and Oct-1
    • Subramaniam N, Cairns W, and Okret S (1998) Glucocorticoids repress transcription from a negative glucocorticoid response element recognized by two homeodomaincontaining proteins, Pbx and Oct-1. J Biol Chem 273:23567-23574.
    • (1998) J Biol Chem , vol.273 , pp. 23567-23574
    • Subramaniam, N.1    Cairns, W.2    Okret, S.3
  • 145
    • 0030881742 scopus 로고    scopus 로고
    • Jun N-terminal kinase/stressactivated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: Glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK
    • Swantek JL, Cobb MH, and Geppert TD (1997) Jun N-terminal
    • (1997) Mol Cell Biol , vol.17 , pp. 6274-6282
    • Swantek, J.L.1    Cobb, M.H.2    Geppert, T.D.3
  • 146
    • 0036265581 scopus 로고    scopus 로고
    • Glucocorticoid responsiveness of the rat phenylethanolamine N-methyltransferase gene
    • Tai TC, Claycomb R, Her S, Bloom AK, and Wong DL (2002) Glucocorticoid responsiveness of the rat phenylethanolamine N-methyltransferase gene. Mol Pharmacol 61:1385-1392.
    • (2002) Mol Pharmacol , vol.61 , pp. 1385-1392
    • Tai, T.C.1    Claycomb, R.2    Her, S.3    Bloom, A.K.4    Wong, D.L.5
  • 147
    • 0031743573 scopus 로고    scopus 로고
    • Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: Synergistic activation of IL-6 response element by IL-6 and glucocorticoid
    • Takeda T, Kurachi H, Yamamoto T, Nishio Y, Nakatsuji Y, Morishige K, Miyake A, and Murata Y (1998) Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: synergistic activation of IL-6 response element by IL-6 and glucocorticoid. J Endocrinol 159:323-330.
    • (1998) J Endocrinol , vol.159 , pp. 323-330
    • Takeda, T.1    Kurachi, H.2    Yamamoto, T.3    Nishio, Y.4    Nakatsuji, Y.5    Morishige, K.6    Miyake, A.7    Murata, Y.8
  • 148
    • 0347266562 scopus 로고    scopus 로고
    • Cell type-dependent divergence of transactivation by glucocorticoid receptor ligand
    • Tanigawa K, Tanaka K, Nagase H, Miyake H, Kiniwa M, and Ikizawa K (2002) Cell type-dependent divergence of transactivation by glucocorticoid receptor ligand. Biol Pharm Bull 25:1619-1622.
    • (2002) Biol Pharm Bull , vol.25 , pp. 1619-1622
    • Tanigawa, K.1    Tanaka, K.2    Nagase, H.3    Miyake, H.4    Kiniwa, M.5    Ikizawa, K.6
  • 149
    • 0035951781 scopus 로고    scopus 로고
    • Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-κB and induction of apoptosis
    • Tao Y, Williams-Skipp C, and Scheinman RI (2001) Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-κB and induction of apoptosis. J Biol Chem 276:2329-2332.
    • (2001) J Biol Chem , vol.276 , pp. 2329-2332
    • Tao, Y.1    Williams-Skipp, C.2    Scheinman, R.I.3
  • 150
    • 0029032699 scopus 로고
    • The glucocorticoid receptor synergizes with Jun homodimers to activate AP-1-regulated promoters lacking GR binding sites
    • Teurich S and Angel P (1995) The glucocorticoid receptor synergizes with Jun homodimers to activate AP-1-regulated promoters lacking GR binding sites. Chem Senses 20:251-255.
    • (1995) Chem Senses , vol.20 , pp. 251-255
    • Teurich, S.1    Angel, P.2
  • 151
    • 0026548427 scopus 로고
    • Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts
    • Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, and Fey MF (1992) Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood 79:45-51.
    • (1992) Blood , vol.79 , pp. 45-51
    • Tobler, A.1    Meier, R.2    Seitz, M.3    Dewald, B.4    Baggiolini, M.5    Fey, M.F.6
  • 153
    • 0033611050 scopus 로고    scopus 로고
    • The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin
    • Tuckermann JP, Reichardt HM, Arribas R, Richter KH, Schutz G, and Angel P (1999) The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin. J Cell Biol 147:1365-1370.
    • (1999) J Cell Biol , vol.147 , pp. 1365-1370
    • Tuckermann, J.P.1    Reichardt, H.M.2    Arribas, R.3    Richter, K.H.4    Schutz, G.5    Angel, P.6
  • 154
    • 18744408211 scopus 로고    scopus 로고
    • A pharmacological approach to enhancing the therapeutic index of corticosteroids in airway inflammatory disease
    • Uings IJ and Farrow SN (2005) A pharmacological approach to enhancing the therapeutic index of corticosteroids in airway inflammatory disease. Curr Opin Pharmacol 5:221-226.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 221-226
    • Uings, I.J.1    Farrow, S.N.2
  • 155
    • 0027992051 scopus 로고
    • 12-O-Tetradecanoylphorbol-13- acetate- and tumor necrosis factor α-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter
    • van de Stolpe A, Caldenhoven E, Stade BG, Koenderman L, Raaijmakers JA, Johnson JP, and van der Saag PT (1994) 12-O-Tetradecanoylphorbol-13- acetate- and tumor necrosis factor α-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter. J Biol Chem 269:6185-6192.
    • (1994) J Biol Chem , vol.269 , pp. 6185-6192
    • van de Stolpe, A.1    Caldenhoven, E.2    Stade, B.G.3    Koenderman, L.4    Raaijmakers, J.A.5    Johnson, J.P.6    van der Saag, P.T.7
  • 156
    • 0032870623 scopus 로고    scopus 로고
    • Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-κB-dependent mechanism
    • Vanden Berghe W, Francesconi E, De Bosscher K, Resche-Rigon M, and Haegeman G (1999) Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-κB-dependent mechanism. Mol Pharmacol 56:797-806.
    • (1999) Mol Pharmacol , vol.56 , pp. 797-806
    • Vanden Berghe, W.1    Francesconi, E.2    De Bosscher, K.3    Resche-Rigon, M.4    Haegeman, G.5
  • 158
    • 0032891082 scopus 로고    scopus 로고
    • Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production
    • Wang J, Zhu Z, Nolfo R, and Elias JA (1999) Dexamethasone regulation of lung epithelial cell and fibroblast interleukin-11 production. Am J Physiol 276:L175-L185.
    • (1999) Am J Physiol , vol.276
    • Wang, J.1    Zhu, Z.2    Nolfo, R.3    Elias, J.A.4
  • 159
  • 160
    • 2542486258 scopus 로고    scopus 로고
    • Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors
    • Wang Q, Blackford JA Jr, Song LN, Huang Y, Cho S, and Simons SS Jr (2004) Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors. Mol Endocrinol 18:1376-1395.
    • (2004) Mol Endocrinol , vol.18 , pp. 1376-1395
    • Wang, Q.1    Blackford Jr, J.A.2    Song, L.N.3    Huang, Y.4    Cho, S.5    Simons Jr, S.S.6
  • 161
    • 0031570836 scopus 로고    scopus 로고
    • Dexamethasone potently enhances phorbol ester-induced IL-1beta gene expression and nuclear factor NF-kappaB activation
    • Wang Y, Zhang JJ, Dai W, Lei KY, and Pike JW (1997) Dexamethasone potently enhances phorbol ester-induced IL-1beta gene expression and nuclear factor NF-kappaB activation. J Immunol 159:534-537.
    • (1997) J Immunol , vol.159 , pp. 534-537
    • Wang, Y.1    Zhang, J.J.2    Dai, W.3    Lei, K.Y.4    Pike, J.W.5
  • 162
    • 0037592259 scopus 로고    scopus 로고
    • Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis
    • Wang Z, Malone MH, He H, McColl KS, and Distelhorst CW (2003) Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J Biol Chem 278:23861-23867.
    • (2003) J Biol Chem , vol.278 , pp. 23861-23867
    • Wang, Z.1    Malone, M.H.2    He, H.3    McColl, K.S.4    Distelhorst, C.W.5
  • 163
    • 33645284675 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein (Txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis
    • Wang Z, Rong YP, Malone MH, Davis MC, Zhong F, and Distelhorst CW (2006b) Thioredoxin-interacting protein (Txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis. Oncogene 25:1903-1913.
    • (2006) Oncogene , vol.25 , pp. 1903-1913
    • Wang, Z.1    Rong, Y.P.2    Malone, M.H.3    Davis, M.C.4    Zhong, F.5    Distelhorst, C.W.6
  • 164
    • 0036773286 scopus 로고    scopus 로고
    • Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types
    • Webster JC, Huber RM, Hanson RL, Collier PM, Haws TF, Mills JK, Burn TC, and Allegretto EA (2002) Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types. Endocrinology 143:3866-3874.
    • (2002) Endocrinology , vol.143 , pp. 3866-3874
    • Webster, J.C.1    Huber, R.M.2    Hanson, R.L.3    Collier, P.M.4    Haws, T.F.5    Mills, J.K.6    Burn, T.C.7    Allegretto, E.A.8
  • 165
    • 0030911732 scopus 로고    scopus 로고
    • Activation of transcription factor NF-κB and P38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
    • Wesselborg S, Bauer MK, Vogt M, Schmitz ML, and Schulze-Osthoff K (1997) Activation of transcription factor NF-κB and P38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways. J Biol Chem 272:12422-12429.
    • (1997) J Biol Chem , vol.272 , pp. 12422-12429
    • Wesselborg, S.1    Bauer, M.K.2    Vogt, M.3    Schmitz, M.L.4    Schulze-Osthoff, K.5
  • 166
    • 0033568608 scopus 로고    scopus 로고
    • The P38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Muller M, Gaestel M, Resch K, and Holtmann H (1999) The P38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 18:4969-4980.
    • (1999) EMBO J , vol.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.Y.5    Shyu, A.B.6    Muller, M.7    Gaestel, M.8    Resch, K.9    Holtmann, H.10
  • 167
    • 0032230316 scopus 로고    scopus 로고
    • Wissink S, van Heerde EC, vand der BB, and van der Saag PT (1998) A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids. Mol Endocrinol 12:355-363.
    • Wissink S, van Heerde EC, vand der BB, and van der Saag PT (1998) A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids. Mol Endocrinol 12:355-363.
  • 168
    • 0346656466 scopus 로고    scopus 로고
    • Repression of P65 transcriptional activation by the glucocorticoid receptor in the absence of receptor-coactivator interactions
    • Wu J, Li Y, Dietz J, and Lala DS (2004) Repression of P65 transcriptional activation by the glucocorticoid receptor in the absence of receptor-coactivator interactions. Mol Endocrinol 18:53-62.
    • (2004) Mol Endocrinol , vol.18 , pp. 53-62
    • Wu, J.1    Li, Y.2    Dietz, J.3    Lala, D.S.4
  • 169
    • 18944375291 scopus 로고    scopus 로고
    • The noncatalytic amino terminus of mitogen-activated protein kinase phosphatase 1 directs nuclear targeting and serum response element transcriptional regulation
    • Wu JJ, Zhang L, and Bennett AM (2005) The noncatalytic amino terminus of mitogen-activated protein kinase phosphatase 1 directs nuclear targeting and serum response element transcriptional regulation. Mol Cell Biol 25:4792-4803.
    • (2005) Mol Cell Biol , vol.25 , pp. 4792-4803
    • Wu, J.J.1    Zhang, L.2    Bennett, A.M.3
  • 170
    • 0035151007 scopus 로고    scopus 로고
    • Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer- binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor
    • Wyszomierski SL and Rosen JM (2001) Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer- binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor. Mol Endocrinol 15:228-240.
    • (2001) Mol Endocrinol , vol.15 , pp. 228-240
    • Wyszomierski, S.L.1    Rosen, J.M.2
  • 171
    • 0032860359 scopus 로고    scopus 로고
    • Steroid-induced conformational changes of rat glucocorticoid receptor cause altered trypsin cleavage of the putative helix 6 in the ligand binding domain
    • Xu M, Modarress KJ, Meeker JE, and Simons SS Jr (1999) Steroid-induced conformational changes of rat glucocorticoid receptor cause altered trypsin cleavage of the putative helix 6 in the ligand binding domain. Mol Cell Endocrinol 155:85-100.
    • (1999) Mol Cell Endocrinol , vol.155 , pp. 85-100
    • Xu, M.1    Modarress, K.J.2    Meeker, J.E.3    Simons Jr, S.S.4
  • 172
    • 0025188132 scopus 로고
    • Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen HF, Chambard JC, Sun YL, Smeal T, Schmidt TJ, Drouin J, and Karin M (1990) Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambard, J.C.2    Sun, Y.L.3    Smeal, T.4    Schmidt, T.J.5    Drouin, J.6    Karin, M.7
  • 173
    • 0033546309 scopus 로고    scopus 로고
    • Dexamethasone alters arachidonate release from human epithelial cells by induction of P11 protein synthesis and inhibition of phospholipase A2 activity
    • Yao XL, Cowan MJ, Gladwin MT, Lawrence MM, Angus CW, and Shelhamer JH (1999) Dexamethasone alters arachidonate release from human epithelial cells by induction of P11 protein synthesis and inhibition of phospholipase A2 activity. J Biol Chem 274:17202-17208.
    • (1999) J Biol Chem , vol.274 , pp. 17202-17208
    • Yao, X.L.1    Cowan, M.J.2    Gladwin, M.T.3    Lawrence, M.M.4    Angus, C.W.5    Shelhamer, J.H.6
  • 175
    • 14844310210 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: Attenuation of proinflammatory cytokine biosynthesis via feedback control of P38
    • Zhao Q, Shepherd EG, Manson ME, Nelin LD, Sorokin A, and Liu Y (2005) The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of P38. J Biol Chem 280:8101-8108.
    • (2005) J Biol Chem , vol.280 , pp. 8101-8108
    • Zhao, Q.1    Shepherd, E.G.2    Manson, M.E.3    Nelin, L.D.4    Sorokin, A.5    Liu, Y.6


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