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Volumn 37, Issue SUPPL. 1, 2007, Pages

Regulatory T cells - A brief history and perspective

Author keywords

CD25; Foxp3; IL 2; Immunological self tolerance; IPEX; Regulatory T cells; Suppressor T cells

Indexed keywords

CYCLOSPORIN A; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3;

EID: 36249024247     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737593     Document Type: Article
Times cited : (277)

References (76)
  • 1
    • 0034716925 scopus 로고    scopus 로고
    • Sakaguchi, S., Regulatory T cells: Key controllers of immunologic self-tolerance. Cell 2000. 101: 455-458.
    • Sakaguchi, S., Regulatory T cells: Key controllers of immunologic self-tolerance. Cell 2000. 101: 455-458.
  • 2
    • 0014792798 scopus 로고
    • Cell interactions in the induction of tolerance: The role of thymic lymphocytes
    • Gershon, R. K. and Kondo, K., Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 1970. 18: 723-737.
    • (1970) Immunology , vol.18 , pp. 723-737
    • Gershon, R.K.1    Kondo, K.2
  • 4
    • 0342770172 scopus 로고
    • RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex
    • Kronenberg, M., Steinmetz, M., Kobori, J., Kraig, E., Kapp, J. A., Pierce, C. W., Sorensen, C. M. et al., RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex. Proc. Natl. Acad. Sci. USA 1983. 80: 5704-5708.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 5704-5708
    • Kronenberg, M.1    Steinmetz, M.2    Kobori, J.3    Kraig, E.4    Kapp, J.A.5    Pierce, C.W.6    Sorensen, C.M.7
  • 5
    • 0026603775 scopus 로고
    • Revisiting and revising suppressor T cells
    • Bloom, B. R., Salgame, P. and Diamond, B., Revisiting and revising suppressor T cells. Immunol. Today 1992. 13:131-136.
    • (1992) Immunol. Today , vol.13 , pp. 131-136
    • Bloom, B.R.1    Salgame, P.2    Diamond, B.3
  • 6
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler, J. W., Roehm, N. and Marrack, P., T cell tolerance by clonal elimination in the thymus. Cell 1987. 49: 273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 9
    • 0028361047 scopus 로고
    • Role of cytokines in determining T-lymphocyte function
    • O'Garra, A. and Murphy, K., Role of cytokines in determining T-lymphocyte function. Curr. Opin. Immunol. 1994. 6: 458-466.
    • (1994) Curr. Opin. Immunol , vol.6 , pp. 458-466
    • O'Garra, A.1    Murphy, K.2
  • 10
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalitis
    • Chen, Y., Kuchroo, V. K., Inobe, J., Hafler, D. A. and Weiner, H. L., Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalitis. Science 1994. 265: 1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 12
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka, Y. and Sakakura, T., Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 1969. 166: 753-755.
    • (1969) Science , vol.166 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 13
    • 0019823659 scopus 로고
    • Genetic susceptibility to post-thymectomy autoimmune diseases in mice
    • Kojima, A. and Prehn, R. T., Genetic susceptibility to post-thymectomy autoimmune diseases in mice. Immunogenetics 1981. 14: 15-27.
    • (1981) Immunogenetics , vol.14 , pp. 15-27
    • Kojima, A.1    Prehn, R.T.2
  • 14
    • 0015908120 scopus 로고
    • Spontaneous thyroiditis in thymectomized and irradiated Wistar rats
    • Penhale, W. J., Farmer, A., McKenna, R. P. and Irvine, W. J., Spontaneous thyroiditis in thymectomized and irradiated Wistar rats. Clin. Exp. Immunol. 1973. 15: 225-236.
    • (1973) Clin. Exp. Immunol , vol.15 , pp. 225-236
    • Penhale, W.J.1    Farmer, A.2    McKenna, R.P.3    Irvine, W.J.4
  • 16
    • 0027509812 scopus 로고
    • + T cell subset that inhibits this autoimmune potential
    • + T cell subset that inhibits this autoimmune potential. J. Exp. Med. 1993. 177: 627-636.
    • (1993) J. Exp. Med , vol.177 , pp. 627-636
    • Fowell, D.1    Mason, D.2
  • 17
    • 0020451946 scopus 로고
    • Study on cellular events in post-thymectomy autoinumme oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
    • Sakaguchi, S., Takahashi, T. and Nishizuka, Y., Study on cellular events in post-thymectomy autoinumme oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J. Exp. Med. 1982. 156: 1577-1586.
    • (1982) J. Exp. Med , vol.156 , pp. 1577-1586
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 18
    • 0017195863 scopus 로고
    • Thyroiditis in T cell-depleted rats: Suppression of the autoallergic response by reconstitution with normal lymphoid cells
    • Penhale, W. J., Irvine, W. J., Inglis, J. R. and Farmer, A., Thyroiditis in T cell-depleted rats: suppression of the autoallergic response by reconstitution with normal lymphoid cells. Clin. Exp. Immunol. 1976. 25: 6-16.
    • (1976) Clin. Exp. Immunol , vol.25 , pp. 6-16
    • Penhale, W.J.1    Irvine, W.J.2    Inglis, J.R.3    Farmer, A.4
  • 19
    • 0020432846 scopus 로고
    • Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer
    • Sakaguchi, S., Takahashi, T. and Nishizuka, Y., Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer. J. Exp. Med. 1982. 156: 1565-1576.
    • (1982) J. Exp. Med , vol.156 , pp. 1565-1576
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 20
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T-cell subset. I. Evidence for the active participation of T cells in natural self-tolerance: Deficit of a T-cetl subset as a possible cause of autoimmune disease
    • Sakaguchi, S., Fukuma, K., Kuribayashi, K. and Masuda, T., Organ-specific autoimmune diseases induced in mice by elimination of T-cell subset. I. Evidence for the active participation of T cells in natural self-tolerance: deficit of a T-cetl subset as a possible cause of autoimmune disease. J. Exp. Med. 1985. 161: 72-87.
    • (1985) J. Exp. Med , vol.161 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 22
    • 0026761052 scopus 로고
    • Tolerance mechanism in experimental ovarian and gastric autoinumme disease
    • Smith, H., Lou, Y. H., Iacy, P. and Tung, K. S. K. Tolerance mechanism in experimental ovarian and gastric autoinumme disease. J. Immunol. 1992. 149: 2212-2218
    • (1992) J. Immunol , vol.149 , pp. 2212-2218
    • Smith, H.1    Lou, Y.H.2    Iacy, P.3    Tung, K.S.K.4
  • 25
    • 0029150110 scopus 로고
    • Immunologic tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. and Toda, M., Immunologic tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995. 155: 1151-1164.
    • (1995) J. Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 26
    • 0029788211 scopus 로고    scopus 로고
    • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
    • Asano, M., Toda, M., Sakaguchi, N. and Sakaguchi, S., Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 1996. 184: 387-396.
    • (1996) J. Exp. Med , vol.184 , pp. 387-396
    • Asano, M.1    Toda, M.2    Sakaguchi, N.3    Sakaguchi, S.4
  • 30
    • 0033064551 scopus 로고    scopus 로고
    • Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells
    • Suri-Payer, E., Amar, A. Z., McHugh, R., Natarajan, K., Margulies, D. H. and Shevach, E. M., Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells. Eur. J. Immunol. 1999. 29: 669-677.
    • (1999) Eur. J. Immunol , vol.29 , pp. 669-677
    • Suri-Payer, E.1    Amar, A.Z.2    McHugh, R.3    Natarajan, K.4    Margulies, D.H.5    Shevach, E.M.6
  • 31
    • 0031939403 scopus 로고    scopus 로고
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 1998. 160: 1212-1218.
    • (1998) J. Immunol , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 32
    • 0025899598 scopus 로고
    • Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
    • Schorle, H., Holtschke, T., Hunig, T., Schimpl, A. and Horak, I., Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 1991. 352: 621-624.
    • (1991) Nature , vol.352 , pp. 621-624
    • Schorle, H.1    Holtschke, T.2    Hunig, T.3    Schimpl, A.4    Horak, I.5
  • 34
    • 0028784289 scopus 로고
    • Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford, D. M., Chen, J., Ferry, J. A., Davidson, L., Ma, A. and Alt, F. W. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995. 3: 521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 35
    • 0342632839 scopus 로고    scopus 로고
    • Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo
    • Suzuki, H., Zhou, Y. W., Kato, M. and Mak, T. W. and Nakashima, I., Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo. J. Exp. Med. 1999. 190: 1561-1572.
    • (1999) J. Exp. Med , vol.190 , pp. 1561-1572
    • Suzuki, H.1    Zhou, Y.W.2    Kato, M.3    Mak, T.W.4    Nakashima, I.5
  • 36
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory Tcells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
    • Malek, T. R., Yu, A., Vincek, V., Scibelli, P. and Kong, L., CD4 regulatory Tcells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 2002. 17: 167-178.
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 37
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 2005. 201: 723-735.
    • (2005) J. Exp. Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 39
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interieukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interieukin 2 production. J. Exp. Med. 1998. 188: 287-296.
    • (1998) J. Exp. Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 40
    • 0035806289 scopus 로고    scopus 로고
    • + suppressor T cells
    • + suppressor T cells. J. Exp. Med. 2001. 193: F41-F46.
    • (2001) J. Exp. Med , vol.193
    • Shevach, E.M.1
  • 41
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B., Clark, L. B., Yasayko, S. A., Wilkinson, J. E. et al., Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 2001. 27: 68-73.
    • (2001) Nat. Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3    Paeper, B.4    Clark, L.B.5    Yasayko, S.A.6    Wilkinson, J.E.7
  • 42
    • 0034526617 scopus 로고    scopus 로고
    • JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
    • Chatila, T. A., Blaeser, F., Ho, N., Lederman, H. M., Voulgaropoulos, C., Helms, C. and Bowcock, A. M., JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 2000. 106: R75-R81.
    • (2000) J. Clin. Invest , vol.106
    • Chatila, T.A.1    Blaeser, F.2    Ho, N.3    Lederman, H.M.4    Voulgaropoulos, C.5    Helms, C.6    Bowcock, A.M.7
  • 43
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin, R. S., Ramsdell, F., Peake, J., Faravelli, F., Casanova, J. L., Buist, N., Levy-Lahad, E. et al., X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 2001. 27: 18-20.
    • (2001) Nat. Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3    Faravelli, F.4    Casanova, J.L.5    Buist, N.6    Levy-Lahad, E.7
  • 44
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M. E., Ferguson, P. J., Whitesell, L., Kelly, T. E. et al., The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 2001. 27: 20-21.
    • (2001) Nat. Genet , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3    Brunkow, M.E.4    Ferguson, P.J.5    Whitesell, L.6    Kelly, T.E.7
  • 45
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. and Sakaguchi, S., Control of regulatory T cell development by the transcription factor Foxp3. Science 2003. 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 49
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim, J. M., Rasmussen, J. P. and Rudensky, A. Y., Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 2007. 8: 191-197.
    • (2007) Nat. Immunol , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 52
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
    • Zheng, Y., Josefowicz, S. Z., Kas, A., Chu, T. T., Gavin, M. A. and Rudensky, A. Y., Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 2007. 445: 936-940.
    • (2007) Nature , vol.445 , pp. 936-940
    • Zheng, Y.1    Josefowicz, S.Z.2    Kas, A.3    Chu, T.T.4    Gavin, M.A.5    Rudensky, A.Y.6
  • 54
    • 33746228122 scopus 로고    scopus 로고
    • FOXP3 controls regulatory T cell function through cooperation with NFAT
    • Wu, Y., Borde, M., Heissmeyer, V., Feuerer, M., Lapan, A. D., Stroud, J. C., Bates, D. L. et al., FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 2006. 126: 375-387.
    • (2006) Cell , vol.126 , pp. 375-387
    • Wu, Y.1    Borde, M.2    Heissmeyer, V.3    Feuerer, M.4    Lapan, A.D.5    Stroud, J.C.6    Bates, D.L.7
  • 56
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy, K. J. and Powrie, F., Regulatory T cells in the control of immune pathology. Nat. Immunol. 2001. 2: 816-822.
    • (2001) Nat. Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 57
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H., Mechanisms of suppression by suppressor T cells. Nat. Immunol. 2005. 6: 338-344.
    • (2005) Nat. Immunol , vol.6 , pp. 338-344
    • von Boehmer, H.1
  • 59
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou, I. and von Boehmer, H., In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 2004. 199: 1401-1408.
    • (2004) J. Exp. Med , vol.199 , pp. 1401-1408
    • Apostolou, I.1    von Boehmer, H.2
  • 63
    • 10844252294 scopus 로고    scopus 로고
    • + regulatory cell activation and function by dendritic cells
    • + regulatory cell activation and function by dendritic cells. Int. Immunol. 2004. 16: 1769-1780.
    • (2004) Int. Immunol , vol.16 , pp. 1769-1780
    • Fehervari, Z.1    Sakaguchi, S.2
  • 64
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25 + T cell-mediated suppression by dendritic cells
    • Pasare, C. and Medzhitov, R., Toll pathway-dependent blockade of CD4+CD25 + T cell-mediated suppression by dendritic cells. Science. 2003. 299: 1033-1036.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 65
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. and Stockinger, B., TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006. 24: 179-189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 66
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L. and Kuchroo, V. K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006. 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 67
    • 33947162110 scopus 로고    scopus 로고
    • Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
    • Laurence, A., Tato, C. M., Davidson, T. S, Kanno, Y., Chen, Z., Yao, Z., Blank, R. B. et al., Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007 26: 371-381.
    • (2007) Immunity , vol.26 , pp. 371-381
    • Laurence, A.1    Tato, C.M.2    Davidson, T.S.3    Kanno, Y.4    Chen, Z.5    Yao, Z.6    Blank, R.B.7
  • 68
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007. 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 69
    • 0032947236 scopus 로고    scopus 로고
    • QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing 112
    • Encinas, J. A., Wicker, L. S., Peterson, L. B., Mukasa, A., Teuscher, C., Sobel, R., Weiner, H. L. et al., QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing 112. Nat. Genet. 1999. 21: 158-160.
    • (1999) Nat. Genet , vol.21 , pp. 158-160
    • Encinas, J.A.1    Wicker, L.S.2    Peterson, L.B.3    Mukasa, A.4    Teuscher, C.5    Sobel, R.6    Weiner, H.L.7
  • 71
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 2004. 22: 531-562.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 74
    • 0029659049 scopus 로고    scopus 로고
    • Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
    • Le Douarin, N., Corbel, C., Bandeira, A., Thomas-Vaslin, V., Modigliani, Y., Coutinho, A. and Salaun, J., Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells. Immunol. Rev. 1996. 149: 35-53.
    • (1996) Immunol. Rev , vol.149 , pp. 35-53
    • Le Douarin, N.1    Corbel, C.2    Bandeira, A.3    Thomas-Vaslin, V.4    Modigliani, Y.5    Coutinho, A.6    Salaun, J.7
  • 75
    • 33746342782 scopus 로고    scopus 로고
    • Infectious tolerance and the long-term acceptance of transplanted tissue
    • Waldmann, H., Adams, E., Fairchild, P. and Cobbold, S., Infectious tolerance and the long-term acceptance of transplanted tissue. Immunol. Rev. 2006. 212: 301-313.
    • (2006) Immunol. Rev , vol.212 , pp. 301-313
    • Waldmann, H.1    Adams, E.2    Fairchild, P.3    Cobbold, S.4
  • 76
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: Multiple varieties of T regulatory cells
    • Shevach, E. M., From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 2006. 25: 195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.