메뉴 건너뛰기




Volumn 8, Issue 3, 2007, Pages 277-284

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

EID: 34247271308     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1437     Document Type: Article
Times cited : (735)

References (37)
  • 2
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 4
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6, 345-352 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 5
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
    • Fontenot, J.D. et al. Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity 22, 329-341 (2005).
    • (2005) Immunity , vol.22 , pp. 329-341
    • Fontenot, J.D.1
  • 6
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim, J., Rasmussen, J.P. & Rudensky, A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8, 191-197 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 191-197
    • Kim, J.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 7
    • 33847220736 scopus 로고    scopus 로고
    • Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
    • in the press
    • Zheng, Y. et al. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature (in the press).
    • Nature
    • Zheng, Y.1
  • 8
    • 0034888424 scopus 로고    scopus 로고
    • Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity
    • Silver, D.P. & Livingston, D.M. Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol. Cell 8, 233-243 (2001).
    • (2001) Mol. Cell , vol.8 , pp. 233-243
    • Silver, D.P.1    Livingston, D.M.2
  • 9
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4 (2001).
    • (2001) BMC Dev. Biol , vol.1 , pp. 4
    • Srinivas, S.1
  • 10
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot, J.D., Rasmussen, J.P., Gavin, M.A. & Rudensky, A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6, 1142-1151 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 11
    • 33745817085 scopus 로고    scopus 로고
    • + T reg cells
    • + T reg cells. J. Exp. Med. 203, 1701-1711 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 1701-1711
    • Liu, W.1
  • 12
    • 0035576221 scopus 로고    scopus 로고
    • The amount of scurfin protein determines peripheral T cell number and responsiveness
    • Khattri, R. et al. The amount of scurfin protein determines peripheral T cell number and responsiveness. J. Immunol. 167 6312-6320 (2001).
    • (2001) J. Immunol , vol.167 , pp. 6312-6320
    • Khattri, R.1
  • 13
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli, E., Dastrange, M. & Oukka, M. Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells. Proc. Natl. Acad. Sci. USA 102, 5138-5143 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 14
    • 33646577466 scopus 로고    scopus 로고
    • H17 and regulatory T cells
    • H17 and regulatory T cells. Nature 441, 235-238 (2006).
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1
  • 15
    • 33748588423 scopus 로고    scopus 로고
    • + helper cells
    • + helper cells. Cell 126, 1121-1133 (2006).
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1
  • 17
    • 0036233983 scopus 로고    scopus 로고
    • Transcription: Tantalizing times for T cells
    • Ho, I.C. & Glimcher, L.H. Transcription: Tantalizing times for T cells. Cell 109, S109-S120 (2002).
    • (2002) Cell , vol.109
    • Ho, I.C.1    Glimcher, L.H.2
  • 18
    • 9244263631 scopus 로고    scopus 로고
    • H2 responses
    • H2 responses. Nat. Immunol. 5, 1157-1165 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 1157-1165
    • Zhu, J.1
  • 19
    • 1242274405 scopus 로고    scopus 로고
    • GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
    • Pai, S.Y., Truitt, M.L. & Ho, I.C. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc. Natl. Acad. Sci. USA 101, 1993-1998 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1993-1998
    • Pai, S.Y.1    Truitt, M.L.2    Ho, I.C.3
  • 20
    • 27144526101 scopus 로고    scopus 로고
    • Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression
    • Martins, G.A., Hutchins, A.S. & Reiner, S.L. Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression. J. Immunol. 175, 5981-5985 (2005).
    • (2005) J. Immunol , vol.175 , pp. 5981-5985
    • Martins, G.A.1    Hutchins, A.S.2    Reiner, S.L.3
  • 21
    • 0034679560 scopus 로고    scopus 로고
    • + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192, 303-310 (2000).
    • (2000) J. Exp. Med , vol.192 , pp. 303-310
    • Takahashi, T.1
  • 22
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust, S., Lu, L., McCarty, N. & Cantor, H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc. Natl. Acad. Sci. USA 101, 10398-10403 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 23
    • 33750375612 scopus 로고    scopus 로고
    • + T cells during cure of colitis
    • + T cells during cure of colitis. J. Immunol. 177, 5852-5860 (2006).
    • (2006) J. Immunol , vol.177 , pp. 5852-5860
    • Uhlig, H.H.1
  • 25
    • 0033763306 scopus 로고    scopus 로고
    • Control of experimental inflammatory bowel disease by regulatory T cells
    • Asseman, C., Fowler, S. & Powrie, F. Control of experimental inflammatory bowel disease by regulatory T cells. Am. J. Respir. Crit. Care Med. 162, S185-S189 (2000).
    • (2000) Am. J. Respir. Crit. Care Med , vol.162
    • Asseman, C.1    Fowler, S.2    Powrie, F.3
  • 26
    • 0036798380 scopus 로고    scopus 로고
    • The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells
    • Yegutkin, G.G., Henttinen, T., Samburski, S.S., Spychala, J. & Jalkanen, S. The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells. Biochem. J. 367, 121-128 (2002).
    • (2002) Biochem. J , vol.367 , pp. 121-128
    • Yegutkin, G.G.1    Henttinen, T.2    Samburski, S.S.3    Spychala, J.4    Jalkanen, S.5
  • 27
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • Ohta, A. & Sitkovsky, M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414, 916-920 (2001).
    • (2001) Nature , vol.414 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 28
    • 33750832563 scopus 로고    scopus 로고
    • T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
    • Kobie, J.J. et al. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine. J. Immunol. 177, 6780-6786 (2006).
    • (2006) J. Immunol , vol.177 , pp. 6780-6786
    • Kobie, J.J.1
  • 29
    • 0345570521 scopus 로고    scopus 로고
    • The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
    • Villarino, A. et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 19, 645-655 (2003).
    • (2003) Immunity , vol.19 , pp. 645-655
    • Villarino, A.1
  • 30
    • 0037446535 scopus 로고    scopus 로고
    • Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: Suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells
    • Chan, C.W. et al. Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: Suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells. J. Immunol. 170, 4036-4044 (2003).
    • (2003) J. Immunol , vol.170 , pp. 4036-4044
    • Chan, C.W.1
  • 31
    • 4143066714 scopus 로고    scopus 로고
    • + T cell receptors
    • + T cell receptors. Immunity 21, 267-277 (2004).
    • (2004) Immunity , vol.21 , pp. 267-277
    • Hsieh, C.S.1
  • 32
    • 33645102841 scopus 로고    scopus 로고
    • An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires
    • Hsieh, C.S., Zheng, Y., Liang, Y., Fontenot, J.D. & Rudensky, A.Y. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat. Immunol. 7, 401-410 (2006).
    • (2006) Nat. Immunol , vol.7 , pp. 401-410
    • Hsieh, C.S.1    Zheng, Y.2    Liang, Y.3    Fontenot, J.D.4    Rudensky, A.Y.5
  • 33
    • 33847153417 scopus 로고    scopus 로고
    • Foxp3-dependent programme of regulatory T cell differentiation
    • in the press
    • Gavin, M.A. et al. Foxp3-dependent programme of regulatory T cell differentiation. Nature (in the press).
    • Nature
    • Gavin, M.A.1
  • 35
    • 4143096772 scopus 로고    scopus 로고
    • CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
    • Ohl, L. et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21, 279-288 (2004).
    • (2004) Immunity , vol.21 , pp. 279-288
    • Ohl, L.1
  • 36
    • 28844464837 scopus 로고    scopus 로고
    • Colon lamina propria dendritic cells induce a proinflammatory cytokine response in lamina propria T cells in the SCID mouse model of colitis
    • Drakes, M.L., Blanchard, T.G. & Czinn, S.J. Colon lamina propria dendritic cells induce a proinflammatory cytokine response in lamina propria T cells in the SCID mouse model of colitis. J. Leukoc. Biol. 78, 1291-1300 (2005).
    • (2005) J. Leukoc. Biol , vol.78 , pp. 1291-1300
    • Drakes, M.L.1    Blanchard, T.G.2    Czinn, S.J.3
  • 37
    • 30444435242 scopus 로고    scopus 로고
    • Isolation of lymphocytes and their innate immune characterizations from liver, intestine, lung and uterus
    • Zhang, J.H. et al. Isolation of lymphocytes and their innate immune characterizations from liver, intestine, lung and uterus. Cell. Mol. Immunol. 2, 271-280 (2005).
    • (2005) Cell. Mol. Immunol , vol.2 , pp. 271-280
    • Zhang, J.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.