-
1
-
-
2442522323
-
Autoreactive T cells in healthy individuals
-
Danke, N. A., Koelle, D. M., Yee, C., Beheray, S. and Kwok, W. W. 2004. Autoreactive T cells in healthy individuals. J. Immunol. 172:5967.
-
(2004)
J. Immunol.
, vol.172
, pp. 5967
-
-
Danke, N.A.1
Koelle, D.M.2
Yee, C.3
Beheray, S.4
Kwok, W.W.5
-
2
-
-
25444497719
-
Cutting edge: Direct suppression of B cells by CD4+ CD25+ regulatory T cells
-
Lim, H. W., Hillsamer, P., Banham, A. H. and Kim, C. H. 2005. Cutting edge: Direct suppression of B cells by CD4+ CD25+ regulatory T cells. J. Immunol. 175:4180.
-
(2005)
J. Immunol.
, vol.175
, pp. 4180
-
-
Lim, H.W.1
Hillsamer, P.2
Banham, A.H.3
Kim, C.H.4
-
3
-
-
14744270856
-
Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells
-
Maloy, K. J., Antonelli, L. R., Lefevre, M. and Powrie, F. 2005. Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells. Immunol. Lett. 97:189.
-
(2005)
Immunol. Lett.
, vol.97
, pp. 189
-
-
Maloy, K.J.1
Antonelli, L.R.2
Lefevre, M.3
Powrie, F.4
-
4
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi, S. 2004. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531
-
-
Sakaguchi, S.1
-
5
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
Bluestone, J. A. and Abbas, A. K. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3:253.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 253
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
6
-
-
0035413350
-
CD4+CD25high regulatory cells in human peripheral blood
-
Baecher-Allan, C., Brown, J. A., Freeman, G. J. and Hafler, D. A. 2001. CD4+CD25high regulatory cells in human peripheral blood. J. Immunol. 167:1245.
-
(2001)
J. Immunol.
, vol.167
, pp. 1245
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
7
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. and Toda, M. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
8
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin IL-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi, R., Hori, S., Takahashi, T. and Sakaguchi, S. 2005. Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory Tcells by interleukin IL-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201:723.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 723
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
9
-
-
0036170938
-
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu, J., Yamazaki, S., Takahashi, T., Ishida, Y. and Sakaguchi, S. 2002. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance. Nat. Immunol. 3:135.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 135
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
10
-
-
0036195161
-
CD4+CD25+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh, R. S., Whitters, M. J., Piccirillo, C. A. et al. 2002. CD4+CD25+ immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16:311.
-
(2002)
Immunity
, vol.16
, pp. 311
-
-
McHugh, R.S.1
Whitters, M.J.2
Piccirillo, C.A.3
-
11
-
-
0036791004
-
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells
-
Lehmann, J., Huehn, J., de la Rosa, M. et al. 2002. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells. Proc. Natl Acad. Sci. USA 99:13031.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 13031
-
-
Lehmann, J.1
Huehn, J.2
de la Rosa, M.3
-
12
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
-
Read, S., Malmstrom, V. and Powrie, F. 2000. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J. Exp. Med. 192:295.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
13
-
-
19444383208
-
Frontline: Neuropilin-1: A surface marker of regulatory T cells
-
Bruder, D., Probst-Kepper, M., Westendorf, A. M. et al. 2004. Frontline: neuropilin-1: A surface marker of regulatory T cells. Eur. J. Immunol. 34:1498.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1498
-
-
Bruder, D.1
Probst-Kepper, M.2
Westendorf, A.M.3
-
14
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T., Tagami, T., Yamazaki, S. et al. 2000. Immunologic self-tolerance maintained by CD25+CD4+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192:303.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
-
15
-
-
10344220512
-
cD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion
-
Curotto de Lafaille, M. A., Lino, A. C., Kutchukhidze, N. and Lafaille, J. J. 2004. cd25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion. J. Immunol. 173:7259.
-
(2004)
J. Immunol.
, vol.173
, pp. 7259
-
-
Curotto de Lafaille, M.A.1
Lino, A.C.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
16
-
-
33645776461
-
Control of autoimmune myocarditis and multi-organ inflammation by GITRhigh, Foxp3-expressing CD25+ and CD25- regulatory T cells
-
Ono, M., Shimizu, J., Miyachi, Y. and Sakaguchi, S. 2006. Control of autoimmune myocarditis and multi-organ inflammation by GITRhigh, Foxp3-expressing CD25+ and CD25- regulatory T cells. J. Immunol. 176:4748.
-
(2006)
J. Immunol.
, vol.176
, pp. 4748
-
-
Ono, M.1
Shimizu, J.2
Miyachi, Y.3
Sakaguchi, S.4
-
17
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi, T., Kuniyasu, Y., Toda, M. et al. 1998. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/ suppressive state. Int. Immunol. 10:1969.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
-
18
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid, Y., Piccirillo, C. A., Mendez, S., Shevach, E. M. and Sacks, D. L. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420:502.
-
(2002)
Nature
, vol.420
, pp. 502
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
19
-
-
4344653864
-
Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells
-
Nishimura, E., Sakihama, T., Setoguchi, R., Tanaka, K. and Sakaguchi, S. 2004. Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells. Int. Immunol. 16:1189.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1189
-
-
Nishimura, E.1
Sakihama, T.2
Setoguchi, R.3
Tanaka, K.4
Sakaguchi, S.5
-
20
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood, K. J. and Sakaguchi, S. 2003. Regulatory T cells in transplantation tolerance. Nat. Rev. Immunol. 3:199.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 199
-
-
Wood, K.J.1
Sakaguchi, S.2
-
21
-
-
18944370310
-
CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection
-
Ji, J., Masterson, J., Sun, J. and Soong, L. 2005. CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection. J. Immunol. 174:7147.
-
(2005)
J. Immunol.
, vol.174
, pp. 7147
-
-
Ji, J.1
Masterson, J.2
Sun, J.3
Soong, L.4
-
22
-
-
25844517914
-
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
-
Ko, K., Yamazaki, S., Nakamura, K. et al. 2005. Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. J. Exp. Med. 202:885.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 885
-
-
Ko, K.1
Yamazaki, S.2
Nakamura, K.3
-
23
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton, A. M. and Shevach, E. M. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287
-
-
Thornton, A.M.1
Shevach, E.M.2
-
24
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek, T. R., Yu, A., Vincek, V., Scibelli, P. and Kong, L. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17:167.
-
(2002)
Immunity
, vol.17
, pp. 167
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
25
-
-
0043244867
-
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
-
Walker, L. S., Chodos, A., Eggena, M., Dooms, H. and Abbas, A. K. 2003. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J. Exp. Med. 198:249.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 249
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
26
-
-
0041884743
-
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state
-
Fisson, S., Darrasse-Jeze, G., Litvinova, E. et al. 2003. Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J. Exp. Med. 198:737.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 737
-
-
Fisson, S.1
Darrasse-Jeze, G.2
Litvinova, E.3
-
27
-
-
0041806547
-
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro
-
Klein, L., Khazaie, K. and von Boehmer, H. 2003. In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc. Natl Acad. Sci. USA 100:8886.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 8886
-
-
Klein, L.1
Khazaie, K.2
von Boehmer, H.3
-
28
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen, Y., Kuchroo, V. K., Inobe, J., Hafler, D. A. and Weiner, H. L. 1994. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis. Science 265:1237.
-
(1994)
Science
, vol.265
, pp. 1237
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
29
-
-
0030058433
-
Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells
-
Groux, H., Bigler, M., de Vries, J. E. and Roncarolo, M. G. 1996. Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J. Exp. Med. 184:19.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 19
-
-
Groux, H.1
Bigler, M.2
de Vries, J.E.3
Roncarolo, M.G.4
-
30
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux, H., O'Garra, A., Bigler, M. et al. 1997. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389:737.
-
(1997)
Nature
, vol.389
, pp. 737
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
-
31
-
-
1642410432
-
Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells
-
Verhasselt, V., Vosters, O., Beuneu, C. et al. 2004. Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells. Eur. J. Immunol. 34:762.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 762
-
-
Verhasselt, V.1
Vosters, O.2
Beuneu, C.3
-
32
-
-
0034613767
-
Induction of interleukin 10-producing, nonproliferating CD4+ Tcells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
Jonuleit, H., Schmitt, E., Schuler, G., Knop, J. and Enk, A. H. 2000. Induction of interleukin 10-producing, nonproliferating CD4+ Tcells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192:1213.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1213
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
33
-
-
0012391130
-
Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
-
Sato, K., Yamashita, N., Baba, M. and Matsuyama, T. 2003. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 101:3581.
-
(2003)
Blood
, vol.101
, pp. 3581
-
-
Sato, K.1
Yamashita, N.2
Baba, M.3
Matsuyama, T.4
-
34
-
-
0037987977
-
Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
-
Wakkach, A., Fournier, N., Brun, V., Breittmayer, J. P., Cottrez, F. and Groux, H. 2003. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18:605.
-
(2003)
Immunity
, vol.18
, pp. 605
-
-
Wakkach, A.1
Fournier, N.2
Brun, V.3
Breittmayer, J.P.4
Cottrez, F.5
Groux, H.6
-
35
-
-
0141566334
-
Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes
-
Vigouroux, S., Yvon, E., Wagner, H. J. et al. 2003. Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes. J. Virol. 77:10872.
-
(2003)
J. Virol.
, vol.77
, pp. 10872
-
-
Vigouroux, S.1
Yvon, E.2
Wagner, H.J.3
-
36
-
-
0242493801
-
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells
-
Yvon, E. S., Vigouroux, S., Rousseau, R. F. et al. 2003. Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood 102:3815.
-
(2003)
Blood
, vol.102
, pp. 3815
-
-
Yvon, E.S.1
Vigouroux, S.2
Rousseau, R.F.3
-
37
-
-
0035176364
-
Notch signalling in the regulation of peripheral immunity
-
Hoyne, G. F., Dallman, M. J., Champion, B. R. and Lamb, J. R. 2001. Notch signalling in the regulation of peripheral immunity. Immunol. Rev. 182:215.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 215
-
-
Hoyne, G.F.1
Dallman, M.J.2
Champion, B.R.3
Lamb, J.R.4
-
38
-
-
0035885068
-
Differentiation of regulatory T cells 1 is induced by CD2 costimulation
-
Wakkach, A., Cottrez, F. and Groux, H. 2001. Differentiation of regulatory T cells 1 is induced by CD2 costimulation. J. Immunol. 167:3107.
-
(2001)
J. Immunol.
, vol.167
, pp. 3107
-
-
Wakkach, A.1
Cottrez, F.2
Groux, H.3
-
39
-
-
0347895101
-
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
-
Kemper, C., Chan, A. C., Green, J. M., Brett, K. A., Murphy, K. M. and Atkinson, J. P. 2003. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421:388.
-
(2003)
Nature
, vol.421
, pp. 388
-
-
Kemper, C.1
Chan, A.C.2
Green, J.M.3
Brett, K.A.4
Murphy, K.M.5
Atkinson, J.P.6
-
40
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
Barrat, F. J., Cua, D. J., Boonstra, A. et al. 2002. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195:603.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
-
41
-
-
2442450433
-
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
-
Vieira, P. L., Christensen, J. R., Minaee, S. et al. 2004. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J. Immunol. 172:5986.
-
(2004)
J. Immunol.
, vol.172
, pp. 5986
-
-
Vieira, P.L.1
Christensen, J.R.2
Minaee, S.3
-
42
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
-
Weiner, H. L. 2001. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol. Rev. 182:207.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 207
-
-
Weiner, H.L.1
-
43
-
-
0032525034
-
In situ immune response in gut-associated lymphoid tissue (GALT) following oral antigen in TCR-transgenic mice
-
Gonnella, P. A., Chen, Y., Inobe, J., Komagata, Y., Quartulli, M. and Weiner, H. L. 1998. In situ immune response in gut-associated lymphoid tissue (GALT) following oral antigen in TCR-transgenic mice. J. Immunol. 160:4708.
-
(1998)
J. Immunol.
, vol.160
, pp. 4708
-
-
Gonnella, P.A.1
Chen, Y.2
Inobe, J.3
Komagata, Y.4
Quartulli, M.5
Weiner, H.L.6
-
44
-
-
0042831022
-
Reduced transforming growth factor-beta1-producing T cells in the duodenal mucosa of children with food allergy
-
Perez-Machado, M. A., Ashwood, P., Thomson, M. A. et al. 2003. Reduced transforming growth factor-beta1-producing T cells in the duodenal mucosa of children with food allergy. Eur. J. Immunol. 33:2307.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 2307
-
-
Perez-Machado, M.A.1
Ashwood, P.2
Thomson, M.A.3
-
45
-
-
0036118781
-
Reduced transforming growth factor-beta1 production by mononuclear cells from patients with active chronic idiopathic thrombocytopenic purpura
-
Andersson, P. O., Olsson, A. and Wadenvik, H. 2002. Reduced transforming growth factor-beta1 production by mononuclear cells from patients with active chronic idiopathic thrombocytopenic purpura. Br. J. Haematol. 116:862.
-
(2002)
Br. J. Haematol.
, vol.116
, pp. 862
-
-
Andersson, P.O.1
Olsson, A.2
Wadenvik, H.3
-
46
-
-
25844504653
-
Developmental regulation of Foxp3 expression during ontogeny
-
Fontenot, J. D., Dooley, J. L., Farr, A. G. and Rudensky, A. Y. 2005. Developmental regulation of Foxp3 expression during ontogeny. J. Exp. Med. 202:901.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 901
-
-
Fontenot, J.D.1
Dooley, J.L.2
Farr, A.G.3
Rudensky, A.Y.4
-
47
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan, M. S., Boesteanu, A., Reed, A. J. et al. 2001. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2:301.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
-
48
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot, J. D. and Rudensky, A. Y. 2005. A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol. 6:331.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 331
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
49
-
-
0035920510
-
Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4+25+ immunoregulatory T cells
-
Bensinger, S. J., Bandeira, A., Jordan, M. S., Caton, A. J. and Laufer, T. M. 2001. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4+25+ immunoregulatory T cells. J. Exp. Med. 194:427.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 427
-
-
Bensinger, S.J.1
Bandeira, A.2
Jordan, M.S.3
Caton, A.J.4
Laufer, T.M.5
-
50
-
-
24144480562
-
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
-
Watanabe, N., Wang, Y. H., Lee, H. K., Ito, T., Cao, W. and Liu, Y. J. 2005. Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature 436: 1181.
-
(2005)
Nature
, vol.436
, pp. 1181
-
-
Watanabe, N.1
Wang, Y.H.2
Lee, H.K.3
Ito, T.4
Cao, W.5
Liu, Y.J.6
-
51
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon, B., Lenschow, D. J., Rhee, L. et al. 2000. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12:431.
-
(2000)
Immunity
, vol.12
, pp. 431
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
-
52
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
Tai, X., Cowan, M., Feigenbaum, L. and Singer, A. 2005. CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. Nat. Immunol. 6:152.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 152
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
53
-
-
23844460509
-
Rap1-GTP is a negative regulator of Th cell function and promotes the generation of CD4+CD103+ regulatory T cells in vivo
-
Li, L., Greenwald, R. J., Lafuente, E. M. et al. 2005. Rap1-GTP is a negative regulator of Th cell function and promotes the generation of CD4+CD103+ regulatory T cells in vivo. J. Immunol. 175:3133.
-
(2005)
J. Immunol.
, vol.175
, pp. 3133
-
-
Li, L.1
Greenwald, R.J.2
Lafuente, E.M.3
-
54
-
-
29144533904
-
CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells
-
Marski, M., Kandula, S., Turner, J. R. and Abraham, C. 2005. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. J. Immunol. 175:7889.
-
(2005)
J. Immunol.
, vol.175
, pp. 7889
-
-
Marski, M.1
Kandula, S.2
Turner, J.R.3
Abraham, C.4
-
55
-
-
0033136302
-
Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh, M., Takahashi, T., Sakaguchi, N. et al. 1999. Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162:5317.
-
(1999)
J. Immunol.
, vol.162
, pp. 5317
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
-
56
-
-
0037062420
-
Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice
-
Hori, S., Haury, M., Coutinho, A. and Demengeot, J. 2002. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice. Proc. Natl Acad. Sci. USA 99:8213.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8213
-
-
Hori, S.1
Haury, M.2
Coutinho, A.3
Demengeot, J.4
-
57
-
-
0036568942
-
Generation of CD4+CD25+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
Kawahata, K., Misaki, Y., Yamauchi, M. et al. 2002. Generation of CD4+CD25+ regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J. Immunol. 168:4399.
-
(2002)
J. Immunol.
, vol.168
, pp. 4399
-
-
Kawahata, K.1
Misaki, Y.2
Yamauchi, M.3
-
58
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. and Sakaguchi, S. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057.
-
(2003)
Science
, vol.299
, pp. 1057
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
59
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S. A. and Ramsdell, F. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
60
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J. D., Gavin, M. A. and Rudensky, A. Y. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
61
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Wan, Y. Y. and Flavell, R. A. 2005. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl Acad. Sci. USA 102:5126.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 5126
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
62
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A. et al. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27:68.
-
(2001)
Nat. Genet.
, vol.27
, pp. 68
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
-
63
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Richter, K., Grill, S. M., Shariat, N. et al. 2004. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol. 2:E198.
-
(2004)
PLoS Biol.
, vol.2
-
-
Oswald-Richter, K.1
Grill, S.M.2
Shariat, N.3
-
64
-
-
0346969978
-
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells
-
Walker, M. R., Kasprowicz, D. J., Gersuk, V. H. et al. 2003. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J. Clin. Invest. 112:1437.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1437
-
-
Walker, M.R.1
Kasprowicz, D.J.2
Gersuk, V.H.3
-
65
-
-
8344275995
-
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
-
Yagi, H., Nomura, T., Nakamura, K. et al. 2004. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int. Immunol. 16:1643.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1643
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
-
66
-
-
8644280556
-
Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
-
Weiss, L., Donkova-Petrini, V., Caccavelli, L., Balbo,M., Carbonneil, C. and Levy, Y. 2004. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104:3249.
-
(2004)
Blood
, vol.104
, pp. 3249
-
-
Weiss, L.1
Donkova-Petrini, V.2
Caccavelli, L.3
Balbo, M.4
Carbonneil, C.5
Levy, Y.6
-
67
-
-
0025317650
-
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
-
Lyon, M. F., Peters, J., Glenister, P. H., Ball, S. and Wright, E. 1990. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome. Proc. Natl Acad. Sci. USA 87:2433.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 2433
-
-
Lyon, M.F.1
Peters, J.2
Glenister, P.H.3
Ball, S.4
Wright, E.5
-
68
-
-
2942733256
-
Human CD25+ regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells
-
Stassen, M., Fondel, S., Bopp, T. et al. 2004. Human CD25+ regulatory T cells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells. Eur. J. Immunol. 34:1303.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1303
-
-
Stassen, M.1
Fondel, S.2
Bopp, T.3
-
69
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou, I. and von Boehmer, H. 2004. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199:1401.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1401
-
-
Apostolou, I.1
von Boehmer, H.2
-
70
-
-
0002384347
-
Induction of immunological paralysis in two zones of dosage
-
Mitchison, N. A. 1964. Induction of immunological paralysis in two zones of dosage. Proc. R. Soc. Lond. B Biol. Sci. 161:275.
-
(1964)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.161
, pp. 275
-
-
Mitchison, N.A.1
-
71
-
-
27944455288
-
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen
-
Knoechel, B., Lohr, J., Kahn, E., Bluestone, J. A. and Abbas, A. K. 2005. Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J. Exp. Med. 202:1375.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1375
-
-
Knoechel, B.1
Lohr, J.2
Kahn, E.3
Bluestone, J.A.4
Abbas, A.K.5
-
72
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek, T. R. and Bayer, A. L. 2004. Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 4:665.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 665
-
-
Malek, T.R.1
Bayer, A.L.2
-
73
-
-
7144259082
-
Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik, M., de Moraes, M. L., Pontoux, C., Vasseur, F. and Penit, C. 1998. Regulatory CD4 T cells: Expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10:371.
-
(1998)
Int. Immunol.
, vol.10
, pp. 371
-
-
Papiernik, M.1
de Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
74
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J. D., Rasmussen, J. P., Gavin, M. A. and Rudensky, A. Y. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6:1142.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1142
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
75
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory Tcells by TGF-beta induction of transcription factor Foxp3
-
Chen, W., Jin, W., Hardegen, N. et al. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory Tcells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198:1875.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
76
-
-
14644388075
-
Dominant tolerance: Activation thresholds for peripheral generation of regulatory T cells
-
Graca, L., Chen, T. C., Le Moine, A., Cobbold, S. P., Howie, D. and Waldmann, H. 2005. Dominant tolerance: Activation thresholds for peripheral generation of regulatory T cells. Trends Immunol. 26:130.
-
(2005)
Trends Immunol.
, vol.26
, pp. 130
-
-
Graca, L.1
Chen, T.C.2
Le Moine, A.3
Cobbold, S.P.4
Howie, D.5
Waldmann, H.6
-
77
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer, K., Apostolou, I., Hawiger, D., Khazaie, K., Nussenzweig, M. C. and von Boehmer, H. 2005. Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 6:1219.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1219
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
von Boehmer, H.6
-
78
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Fox p3 expression in CD4+CD25+ regulatory T cells
-
Marie, J. C., Letterio, J. J., Gavin, M. and Rudensky, A. Y. 2005. TGF-beta1 maintains suppressor function and Fox p3 expression in CD4+CD25+ regulatory T cells. J. Exp. Med. 201:1061.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1061
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
79
-
-
4544357207
-
TGFbeta regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo
-
Schramm, C., Huber, S., Protschka, M. et al. 2004. TGFbeta regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo. Int. Immunol. 16:1241.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1241
-
-
Schramm, C.1
Huber, S.2
Protschka, M.3
-
80
-
-
9144219649
-
Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells
-
Huber, S., Schramm, C., Lehr, H. A. et al. 2004. Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells. J. Immunol. 173:6526.
-
(2004)
J. Immunol.
, vol.173
, pp. 6526
-
-
Huber, S.1
Schramm, C.2
Lehr, H.A.3
-
81
-
-
2442425262
-
Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
-
Cobbold, S. P., Castejon, R., Adams, E. et al. 2004. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol. 172:6003.
-
(2004)
J. Immunol.
, vol.172
, pp. 6003
-
-
Cobbold, S.P.1
Castejon, R.2
Adams, E.3
-
82
-
-
0037339812
-
Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
-
Sato, K., Yamashita, N., Baba, M. and Matsuyama, T. 2003. Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse. Immunity 18:367.
-
(2003)
Immunity
, vol.18
, pp. 367
-
-
Sato, K.1
Yamashita, N.2
Baba, M.3
Matsuyama, T.4
-
83
-
-
31144468294
-
CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer
-
Smyth, M. J., Teng, M. W., Swann, J., Kyparissoudis, K., Godfrey, D. I. and Hayakawa, Y. 2006. CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer. J. Immunol. 176:1582.
-
(2006)
J. Immunol.
, vol.176
, pp. 1582
-
-
Smyth, M.J.1
Teng, M.W.2
Swann, J.3
Kyparissoudis, K.4
Godfrey, D.I.5
Hayakawa, Y.6
-
84
-
-
0041589414
-
Human CD4+ CD25+ regulatory T cells suppress NKT cell functions
-
Azuma, T., Takahashi, T., Kunisato, A., Kitamura, T. and Hirai, H. 2003. Human CD4+ CD25+ regulatory T cells suppress NKT cell functions. Cancer Res. 63:4516.
-
(2003)
Cancer Res.
, vol.63
, pp. 4516
-
-
Azuma, T.1
Takahashi, T.2
Kunisato, A.3
Kitamura, T.4
Hirai, H.5
-
85
-
-
0034077559
-
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
Cederbom, L., Hall, H. and Ivars, F. 2000. CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur. J. Immunol. 30:1538.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1538
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
86
-
-
1842581857
-
Cutting edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
-
Misra, N., Bayry, J., Lacroix-Desmazes, S., Kazatchkine, M. D. and Kaveri, S. V. 2004. Cutting edge: Human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J. Immunol. 172:4676.
-
(2004)
J. Immunol.
, vol.172
, pp. 4676
-
-
Misra, N.1
Bayry, J.2
Lacroix-Desmazes, S.3
Kazatchkine, M.D.4
Kaveri, S.V.5
-
87
-
-
15444366582
-
Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells
-
Taams, L. S., van Amelsfort, J. M., Tiemessen, M. M. et al. 2005. Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells. Hum. Immunol. 66:222.
-
(2005)
Hum. Immunol.
, vol.66
, pp. 222
-
-
Taams, L.S.1
van Amelsfort, J.M.2
Tiemessen, M.M.3
-
88
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
Schorle, H., Holtschke, T., Hunig, T., Schimpl, A. and Horak, I. 1991. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 352:621.
-
(1991)
Nature
, vol.352
, pp. 621
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
89
-
-
27544446622
-
Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
-
D'Cruz, L. M. and Klein, L. 2005. Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6:1152.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1152
-
-
D'Cruz, L.M.1
Klein, L.2
-
90
-
-
0035806290
-
Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood
-
Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J. and Enk, A. H. 2001. Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193:1285.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1285
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.H.6
-
91
-
-
0037099613
-
CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
Piccirillo, C. A., Letterio, J. J., Thornton, A. M. et al. 2002. CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J. Exp. Med. 196:237.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
-
92
-
-
0035801335
-
Cell contactdependent immunosuppression by CD4+CD25+ regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura, K., Kitani, A. and Strober, W. 2001. Cell contactdependent immunosuppression by CD4+CD25+ regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 194:629.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
93
-
-
0037026003
-
Phenotype, localization, and mechanism of suppression of CD4+CD25+ human thymocytes
-
Annunziato, F., Cosmi, L., Liotta, F. et al. 2002. Phenotype, localization, and mechanism of suppression of CD4+CD25+ human thymocytes. J. Exp. Med. 196:379.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 379
-
-
Annunziato, F.1
Cosmi, L.2
Liotta, F.3
-
94
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L. and Powrie, F. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190:995.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
95
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer, E. and Cantor, H. 2001. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J. Autoimmun. 16:115.
-
(2001)
J. Autoimmun.
, vol.16
, pp. 115
-
-
Suri-Payer, E.1
Cantor, H.2
-
96
-
-
0037099719
-
Infectious tolerance: Human CD25+ regulatory T cells convey suppressor activity to conventional CD4+ T helper cells
-
Jonuleit, H., Schmitt, E., Kakirman, H., Stassen, M., Knop, J. and Enk, A. H. 2002. Infectious tolerance: Human CD25+ regulatory T cells convey suppressor activity to conventional CD4+ T helper cells. J. Exp. Med. 196:255.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 255
-
-
Jonuleit, H.1
Schmitt, E.2
Kakirman, H.3
Stassen, M.4
Knop, J.5
Enk, A.H.6
-
97
-
-
0037099733
-
Human CD4+CD25+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
-
Dieckmann, D., Bruett, C. H., Ploettner, H., Lutz, M. B. and Schuler, G. 2002. Human CD4+CD25+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells. J. Exp. Med. 196:247.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 247
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
98
-
-
0033985780
-
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
-
Thornton, A. M. and Shevach, E. M. 2000. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J. Immunol. 164:183.
-
(2000)
J. Immunol.
, vol.164
, pp. 183
-
-
Thornton, A.M.1
Shevach, E.M.2
-
99
-
-
0347994958
-
B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions
-
Taylor, P. A., Lees, C. J., Fournier, S., Allison, J. P., Sharpe, A. H. and Blazar, B. R. 2004. B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions. J. Immunol. 172:34.
-
(2004)
J. Immunol.
, vol.172
, pp. 34
-
-
Taylor, P.A.1
Lees, C.J.2
Fournier, S.3
Allison, J.P.4
Sharpe, A.H.5
Blazar, B.R.6
-
100
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
Paust, S., Lu, L., McCarty, N. and Cantor, H. 2004. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc. Natl Acad. Sci. USA 101:10398.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10398
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
101
-
-
9244261022
-
Distinct roles of CTLA-4 and TGF-beta in CD4(+)CD25(+) regulatory T cell function
-
Tang, Q., Boden, E. K., Henriksen, K. J., Bour-Jordan, H., Bi, M. and Bluestone, J. A. 2004. Distinct roles of CTLA-4 and TGF-beta in CD4(+)CD25(+) regulatory T cell function. Eur. J. Immunol. 34:2996.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2996
-
-
Tang, Q.1
Boden, E.K.2
Henriksen, K.J.3
Bour-Jordan, H.4
Bi, M.5
Bluestone, J.A.6
-
102
-
-
33646567156
-
Activated CD4+CD25+ T cells selectively kill B lymphocytes
-
Zhao, D. M., Thornton, A. M., Dipaolo, R. J. and Shevach, E. M. 2006. Activated CD4+CD25+ T cells selectively kill B lymphocytes. Blood 107:3925.
-
(2006)
Blood
, vol.107
, pp. 3925
-
-
Zhao, D.M.1
Thornton, A.M.2
Dipaolo, R.J.3
Shevach, E.M.4
-
103
-
-
13544271161
-
Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
-
Gondek, D. C., Lu, L. F., Quezada, S. A., Sakaguchi, S. and Noelle, R. J. 2005. Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J. Immunol. 174:1783.
-
(2005)
J. Immunol.
, vol.174
, pp. 1783
-
-
Gondek, D.C.1
Lu, L.F.2
Quezada, S.A.3
Sakaguchi, S.4
Noelle, R.J.5
-
104
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
Grossman, W. J., Verbsky, J. W., Barchet, W., Colonna, M., Atkinson, J. P. and Ley, T. J. 2004. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 21:589.
-
(2004)
Immunity
, vol.21
, pp. 589
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
105
-
-
28244477625
-
Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity
-
Sojka, D. K., Hughson, A., Sukiennicki, T. L. and Fowell, D. J. 2005. Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity. J. Immunol. 175:7274.
-
(2005)
J. Immunol.
, vol.175
, pp. 7274
-
-
Sojka, D.K.1
Hughson, A.2
Sukiennicki, T.L.3
Fowell, D.J.4
-
106
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
von Boehmer, H. 2005. Mechanisms of suppression by suppressor T cells. Nat. Immunol. 6:338.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 338
-
-
von Boehmer, H.1
-
107
-
-
0347480215
-
CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells
-
Serra, P., Amrani, A., Yamanouchi, J. et al. 2003. CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity 19:877.
-
(2003)
Immunity
, vol.19
, pp. 877
-
-
Serra, P.1
Amrani, A.2
Yamanouchi, J.3
-
108
-
-
10844252294
-
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
-
Fehervari, Z. and Sakaguchi, S. 2004. Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells. Int. Immunol. 16:1769.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1769
-
-
Fehervari, Z.1
Sakaguchi, S.2
-
109
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang, Q., Adams, J. Y., Tooley, A. J. et al. 2006. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat. Immunol. 7:83.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 83
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
-
110
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino, F., Grohmann, U., Hwang, K.W. et al. 2003. Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. 4:1206.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1206
-
-
Fallarino, F.1
Grohmann, U.2
Hwang, K.W.3
-
111
-
-
24644506094
-
CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for co-receptor function
-
Schneider, H., Valk, E., da Rocha Dias, S., Wei, B. and Rudd, C. E. 2005. CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for co-receptor function. Proc. Natl Acad. Sci. USA 102:12861.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12861
-
-
Schneider, H.1
Valk, E.2
da Rocha Dias, S.3
Wei, B.4
Rudd, C.E.5
-
112
-
-
0036284229
-
Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood
-
Wing, K., Ekmark, A., Karlsson, H., Rudin, A. and Suri-Payer, E. 2002. Characterization of human CD25+ CD4+ T cells in thymus, cord and adult blood. Immunology 106:190.
-
(2002)
Immunology
, vol.106
, pp. 190
-
-
Wing, K.1
Ekmark, A.2
Karlsson, H.3
Rudin, A.4
Suri-Payer, E.5
-
114
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki, S., Iyoda, T., Tarbell, K. et al. 2003. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198:235.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 235
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
-
115
-
-
0036883944
-
Inhibition of human CD4+CD25+high regulatory T cell function
-
Baecher-Allan, C., Viglietta, V. and Hafler, D. A. 2002. Inhibition of human CD4+CD25+high regulatory T cell function. J. Immunol. 169:6210.
-
(2002)
J. Immunol.
, vol.169
, pp. 6210
-
-
Baecher-Allan, C.1
Viglietta, V.2
Hafler, D.A.3
-
116
-
-
6344279933
-
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells
-
Stephens, G. L., McHugh, R. S., Whitters, M. J. et al. 2004. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J. Immunol. 173:5008.
-
(2004)
J. Immunol.
, vol.173
, pp. 5008
-
-
Stephens, G.L.1
McHugh, R.S.2
Whitters, M.J.3
-
117
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare, C. and Medzhitov, R. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299:1033.
-
(2003)
Science
, vol.299
, pp. 1033
-
-
Pasare, C.1
Medzhitov, R.2
-
118
-
-
23944509107
-
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
-
Peng, G., Guo, Z., Kiniwa, Y. et al. 2005. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 309:1380.
-
(2005)
Science
, vol.309
, pp. 1380
-
-
Peng, G.1
Guo, Z.2
Kiniwa, Y.3
-
119
-
-
32444432610
-
Toll-like receptor 2 controls expansion and function of regulatory T cells
-
Sutmuller, R. P., den Brok, M. H., Kramer, M. et al. 2006. Toll-like receptor 2 controls expansion and function of regulatory T cells. J. Clin. Invest. 116:485.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 485
-
-
Sutmuller, R.P.1
den Brok, M.H.2
Kramer, M.3
-
120
-
-
29144534608
-
Human CD4+ Tcells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells
-
Crellin, N. K., Garcia, R. V., Hadisfar, O., Allan, S. E., Steiner, T. S. and Levings, M. K. 2005. Human CD4+ Tcells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J. Immunol. 175:8051.
-
(2005)
J. Immunol.
, vol.175
, pp. 8051
-
-
Crellin, N.K.1
Garcia, R.V.2
Hadisfar, O.3
Allan, S.E.4
Steiner, T.S.5
Levings, M.K.6
-
121
-
-
0037450804
-
Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
-
Caramalho, I., Lopes-Carvalho, T., Ostler, D. et al. 2003. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J. Exp. Med. 197:403.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 403
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
|