-
1
-
-
2542486456
-
Asthma: Mechanisms of disease persistence and progression
-
Cohn, L., Elias, J. A. and Chupp, G. L. 2004. Asthma: Mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22:789.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 789
-
-
Cohn, L.1
Elias, J.A.2
Chupp, G.L.3
-
2
-
-
0028821825
-
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
-
Gavett, S. H., O'Hearn, D. J., Li, X., Huang, S. K., Finkelman, F. D. and Wills-Karp, M. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1527
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Li, X.3
Huang, S.K.4
Finkelman, F.D.5
Wills-Karp, M.6
-
3
-
-
0037059462
-
Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
-
Szabo, S. J., Sullivan, B. M., Stemmann, C., Satoskar, A. R., Sleckman, B. P. and Glimcher, L. H. 2002. Distinct effects of T-bet in Th1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science 295:338.
-
(2002)
Science
, vol.295
, pp. 338
-
-
Szabo, S.J.1
Sullivan, B.M.2
Stemmann, C.3
Satoskar, A.R.4
Sleckman, B.P.5
Glimcher, L.H.6
-
4
-
-
0038195719
-
Molecular mechanisms regulating Th1 immune responses
-
Szabo, S. J., Sullivan, B. M., Peng, S. L. and Glimcher, L. H. 2003. Molecular mechanisms regulating Th1 immune responses. Annu. Rev. Immunol. 21:713.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 713
-
-
Szabo, S.J.1
Sullivan, B.M.2
Peng, S.L.3
Glimcher, L.H.4
-
5
-
-
0037059509
-
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
-
Finotto, S., Neurath, M. F., Glickman, J. N. et al. 2002. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295:336.
-
(2002)
Science
, vol.295
, pp. 336
-
-
Finotto, S.1
Neurath, M.F.2
Glickman, J.N.3
-
6
-
-
1442283556
-
T cell directives for transcriptional regulation in asthma
-
Finotto, S. and Glimcher, L. H. 2004. T cell directives for transcriptional regulation in asthma. Springer Semin. Immunopathol. 25:281.
-
(2004)
Springer Semin. Immunopathol.
, vol.25
, pp. 281
-
-
Finotto, S.1
Glimcher, L.H.2
-
7
-
-
0036721057
-
IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblasts
-
Simmons, J. G., Pucilowska, J. B., Keku, T. O. and Lund, P. K. 2002. IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblasts. Am. J. Physiol. Gastrointest. Liver Physiol. 283:G809.
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.283
-
-
Simmons, J.G.1
Pucilowska, J.B.2
Keku, T.O.3
Lund, P.K.4
-
8
-
-
0034802397
-
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma
-
Richter, A., Puddicombe, S. M., Lordan, J. L. et al. 2001. The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am. J. Respir. Cell Mol. Biol. 25:385.
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.25
, pp. 385
-
-
Richter, A.1
Puddicombe, S.M.2
Lordan, J.L.3
-
9
-
-
0032523927
-
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma
-
Doucet, C., Brouty-Boye, D., Pottin-Clemenceau, C., Canonica, G.W., Jasmin, C. and Azzarone, B. 1998. Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. J. Clin. Invest. 101:2129.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2129
-
-
Doucet, C.1
Brouty-Boye, D.2
Pottin-Clemenceau, C.3
Canonica, G.W.4
Jasmin, C.5
Azzarone, B.6
-
10
-
-
0037335831
-
Interleukin-13 induces surfactant function abnormality in the murine lung
-
Zhu, Z., Enhorning, G., Zheng, T. et al. 2003. Interleukin-13 induces surfactant function abnormality in the murine lung. Chest 123:375S.
-
(2003)
Chest
, vol.123
-
-
Zhu, Z.1
Enhorning, G.2
Zheng, T.3
-
11
-
-
2942668626
-
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation
-
Zhu, Z., Zheng, T., Homer, R. J. et al. 2004. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 304:1678.
-
(2004)
Science
, vol.304
, pp. 1678
-
-
Zhu, Z.1
Zheng, T.2
Homer, R.J.3
-
12
-
-
0035903306
-
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β
-
Lee, C. G., Homer, R. J., Zhu, Z. et al. 2001. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β. J. Exp. Med. 194:809.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 809
-
-
Lee, C.G.1
Homer, R.J.2
Zhu, Z.3
-
13
-
-
0037197942
-
Asthma: T-bet- a master controller?
-
Robinson, D. S. and Lloyd, C. M. 2002. Asthma: T-bet- a master controller? Curr. Biol. 12:R322.
-
(2002)
Curr. Biol.
, vol.12
-
-
Robinson, D.S.1
Lloyd, C.M.2
-
14
-
-
0035806279
-
Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of gata-3 expression
-
Finotto, S., De Sanctis, G. T., Lehr, H. A. et al. 2001. Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of gata-3 expression. J. Exp. Med. 193:1247.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1247
-
-
Finotto, S.1
De Sanctis, G.T.2
Lehr, H.A.3
-
15
-
-
0037389229
-
T-box genes in human disorders
-
(Spec. no. 1)
-
Packham, E. A. and Brook, J. D. 2003. T-box genes in human disorders. Hum. Mol. Genet. 12(Spec. no. 1):R37.
-
(2003)
Hum. Mol. Genet.
, vol.12
-
-
Packham, E.A.1
Brook, J.D.2
-
16
-
-
0037013930
-
Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation
-
Gorelik, L., Constant, S. and Flavell, R. A. 2002. Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195:1499.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
17
-
-
0034808223
-
Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population
-
Howard, T. D., Whittaker, P. A., Zaiman, A. L. et al. 2001. Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am. J. Respir. Cell Mol. Biol. 25:377.
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.25
, pp. 377
-
-
Howard, T.D.1
Whittaker, P.A.2
Zaiman, A.L.3
-
18
-
-
0035113157
-
Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthma
-
Finotto, S., Buerke, M., Lingnau, K., Schmitt, E., Galle, P. R. and Neurath, M. F. 2001. Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthma. J. Allergy Clin. Immunol. 107:279.
-
(2001)
J. Allergy Clin. Immunol.
, vol.107
, pp. 279
-
-
Finotto, S.1
Buerke, M.2
Lingnau, K.3
Schmitt, E.4
Galle, P.R.5
Neurath, M.F.6
-
19
-
-
0242491040
-
Role of regulatory T cells in allergy and asthma
-
Akbari, O., Stock, P., DeKruyff, R. H. and Umetsu, D. T. 2003. Role of regulatory T cells in allergy and asthma. Curr. Opin. Immunol. 15:627.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 627
-
-
Akbari, O.1
Stock, P.2
DeKruyff, R.H.3
Umetsu, D.T.4
-
20
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Neurath, M. F., Weigmann, B., Finotto, S. et al. 2002. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 195:1129.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1129
-
-
Neurath, M.F.1
Weigmann, B.2
Finotto, S.3
-
21
-
-
2942709797
-
Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells
-
Stassen, M., Jonuleit, H., Muller, C. et al. 2004. Differential regulatory capacity of CD25+ T regulatory cells and preactivated CD25+ T regulatory cells on development, functional activation, and proliferation of Th2 cells. J. Immunol. 173:267.
-
(2004)
J. Immunol.
, vol.173
, pp. 267
-
-
Stassen, M.1
Jonuleit, H.2
Muller, C.3
-
22
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, G. C. and Glimcher, L. H. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100:655.
-
(2000)
Cell
, vol.100
, pp. 655
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, G.C.5
Glimcher, L.H.6
-
23
-
-
0036305450
-
Th cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni, O., Lee, D., Macian, F., Szabo, S. J., Glimcher, L. H. and Rao, A. 2002. Th cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 3:643.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 643
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
24
-
-
0036301997
-
Hlx is induced by and genetically interacts with T-bet to promote heritable Th1 gene induction
-
Mullen, A. C., Hutchins, A. S., High, F. A. et al. 2002. Hlx is induced by and genetically interacts with T-bet to promote heritable Th1 gene induction. Nat. Immunol. 10:652.
-
(2002)
Nat. Immunol.
, vol.10
, pp. 652
-
-
Mullen, A.C.1
Hutchins, A.S.2
High, F.A.3
-
25
-
-
0035997908
-
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
-
Afkarian, M., Sedy, J. R., Yang, J. et al. 2002. T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells. Nat. Immunol. 3:549.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 549
-
-
Afkarian, M.1
Sedy, J.R.2
Yang, J.3
-
26
-
-
0035910037
-
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
-
Lighvani, A. A., Frucht, D. M., Jankovic, D. et al. 2001. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. Proc. Natl Acad. Sci. USA 98:15137.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15137
-
-
Lighvani, A.A.1
Frucht, D.M.2
Jankovic, D.3
-
27
-
-
0035827347
-
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
-
Mullen, A. C., High, F. A., Hutchins, A. S. et al. 2001. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science 292:1907.
-
(2001)
Science
, vol.292
, pp. 1907
-
-
Mullen, A.C.1
High, F.A.2
Hutchins, A.S.3
-
28
-
-
0030236307
-
Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation
-
Ohno, I., Nitta, Y., Yamauchi, K. et al. 1996. Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation. Am. J. Respir. Cell Mol. Biol. 15:404.
-
(1996)
Am. J. Respir. Cell Mol. Biol.
, vol.15
, pp. 404
-
-
Ohno, I.1
Nitta, Y.2
Yamauchi, K.3
-
29
-
-
0031226757
-
Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma
-
Minshall, E. M., Leung, D. Y., Martin, R. J. et al. 1997. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 17:326.
-
(1997)
Am. J. Respir. Cell Mol. Biol.
, vol.17
, pp. 326
-
-
Minshall, E.M.1
Leung, D.Y.2
Martin, R.J.3
-
30
-
-
0035181092
-
Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis
-
Khalil, N., Parekh, T. V., O'Connor, R. et al. 2001. Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis. Thorax 56:907.
-
(2001)
Thorax
, vol.56
, pp. 907
-
-
Khalil, N.1
Parekh, T.V.2
O'Connor, R.3
-
31
-
-
0034178260
-
TGF-beta1 and radiation fibrosis: A master switch and a specific therapeutic target?
-
Martin, M., Lefaix, J. and Delanian, S. 2000. TGF-beta1 and radiation fibrosis: A master switch and a specific therapeutic target? Int. J. Radiat. Oncol. Biol. Phys. 47:277.
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.47
, pp. 277
-
-
Martin, M.1
Lefaix, J.2
Delanian, S.3
-
32
-
-
0034927240
-
Is SMAD3 a major player in signal transduction pathways leading to fibrogenesis?
-
Roberts, A. B., Piek, E., Bottinger, E. P., Ashcroft, G., Mitchell, J. B. and Flanders, K. C. 2001. Is SMAD3 a major player in signal transduction pathways leading to fibrogenesis? Chest 120:43S.
-
(2001)
Chest
, vol.120
-
-
Roberts, A.B.1
Piek, E.2
Bottinger, E.P.3
Ashcroft, G.4
Mitchell, J.B.5
Flanders, K.C.6
-
33
-
-
0037442216
-
Dual roles of IL-4 in lung injury and fibrosis
-
Huaux, F., Liu, T., McGarry, B., Ullenbruch, M. and Phan, S. H. 2003. Dual roles of IL-4 in lung injury and fibrosis. J. Immunol. 170:2083.
-
(2003)
J. Immunol.
, vol.170
, pp. 2083
-
-
Huaux, F.1
Liu, T.2
McGarry, B.3
Ullenbruch, M.4
Phan, S.H.5
-
34
-
-
1642333177
-
Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts
-
Kolodsick, J. E., Toews, G. B., Jakubzick, C. et al. 2004. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J. Immunol. 172:4068.
-
(2004)
J. Immunol.
, vol.172
, pp. 4068
-
-
Kolodsick, J.E.1
Toews, G.B.2
Jakubzick, C.3
-
35
-
-
0037133611
-
Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts
-
Kodera, T., McGaha, T. L., Phelps, R., Paul, W. E. and Bona, C. A. 2002. Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts. Proc. Natl Acad. Sci. USA 99:3800.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3800
-
-
Kodera, T.1
McGaha, T.L.2
Phelps, R.3
Paul, W.E.4
Bona, C.A.5
-
36
-
-
0037911660
-
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
-
Akbari, O., Stock, P., Meyer, E. et al. 2003. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat. Med. 9:582.
-
(2003)
Nat. Med.
, vol.9
, pp. 582
-
-
Akbari, O.1
Stock, P.2
Meyer, E.3
-
37
-
-
1842785209
-
T-bet regulates the terminal maturation and homeostasis of NK and Val4iNKT cells
-
Townsend, M., Weinmann, A. S., Matsuda, J. et al. 2004. T-bet regulates the terminal maturation and homeostasis of NK and Val4iNKT cells. Immunity 20:477.
-
(2004)
Immunity
, vol.20
, pp. 477
-
-
Townsend, M.1
Weinmann, A.S.2
Matsuda, J.3
-
38
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp, M., Luyimbazi, J., Xu, X. et al. 1998. Interleukin-13: central mediator of allergic asthma. Science 282:2258.
-
(1998)
Science
, vol.282
, pp. 2258
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
-
39
-
-
0035888013
-
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity
-
Walter, D. M., McIntire, J. J., Berry, G. et al. 2001. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J. Immunol. 167:4668.
-
(2001)
J. Immunol.
, vol.167
, pp. 4668
-
-
Walter, D.M.1
McIntire, J.J.2
Berry, G.3
-
40
-
-
0037013925
-
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma
-
Mattes, J., Yang, M., Mahalingam, S. et al. 2002. Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J. Exp. Med. 195:1433.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1433
-
-
Mattes, J.1
Yang, M.2
Mahalingam, S.3
-
41
-
-
0036344597
-
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman, D. A., Huang, X., Koth, L. L. et al. 2002. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat. Med. 8:885.
-
(2002)
Nat. Med.
, vol.8
, pp. 885
-
-
Kuperman, D.A.1
Huang, X.2
Koth, L.L.3
-
42
-
-
0034581505
-
The gene encoding interleukin-13: A susceptibility locus for asthma and related traits
-
Wills-Karp, M. 2000. The gene encoding interleukin-13: A susceptibility locus for asthma and related traits. Respir. Res. 1:19.
-
(2000)
Respir. Res.
, vol.1
, pp. 19
-
-
Wills-Karp, M.1
-
43
-
-
0035141618
-
IL-12/IL-13 axis in allergic asthma
-
Wills-Karp, M. 2001. IL-12/IL-13 axis in allergic asthma. J. Allergy Clin. Immunol. 107:9.
-
(2001)
J. Allergy Clin. Immunol.
, vol.107
, pp. 9
-
-
Wills-Karp, M.1
-
44
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu, Z., Homer, R. J., Wang, Z. et al. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 779
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
-
45
-
-
0037108501
-
TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts
-
Wenzel, S. E., Trudeau, J. B., Barnes, S. et al. 2002. TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts. J. Immunol. 169:4613.
-
(2002)
J. Immunol.
, vol.169
, pp. 4613
-
-
Wenzel, S.E.1
Trudeau, J.B.2
Barnes, S.3
-
46
-
-
0036020038
-
Interleukins-4, -5, and -13: Emerging therapeutic targets in allergic disease
-
Foster, P. S., Martinez-Moczygemba, M., Huston, D. P. and Corry, D. B. 2002. Interleukins-4, -5, and -13: Emerging therapeutic targets in allergic disease. Pharmacol. Ther. 94:253.
-
(2002)
Pharmacol. Ther.
, vol.94
, pp. 253
-
-
Foster, P.S.1
Martinez-Moczygemba, M.2
Huston, D.P.3
Corry, D.B.4
-
47
-
-
0035987319
-
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma
-
Kumar, R. K., Herbert, C., Yang, M., Koskinen, A. M., McKenzie, A. N. and Foster, P. S. 2002. Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma. Clin. Exp. Allergy 32:1104.
-
(2002)
Clin. Exp. Allergy
, vol.32
, pp. 1104
-
-
Kumar, R.K.1
Herbert, C.2
Yang, M.3
Koskinen, A.M.4
McKenzie, A.N.5
Foster, P.S.6
-
48
-
-
0037100414
-
Eosinophils express functional IL-13 in eosinophilic inflammatory diseases
-
Schmid-Grendelmeier, P., Altznauer, F., Fischer, B. et al. 2002. Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J. Immunol. 169:1021.
-
(2002)
J. Immunol.
, vol.169
, pp. 1021
-
-
Schmid-Grendelmeier, P.1
Altznauer, F.2
Fischer, B.3
-
49
-
-
18144449996
-
Roles of interleukin-13 and interferon-gamma in lung inflammation
-
Grunig, G., Ford, J. G., Donaldson, D. D. et al. 2002. Roles of interleukin-13 and interferon-gamma in lung inflammation. Chest 121:88S.
-
(2002)
Chest
, vol.121
-
-
Grunig, G.1
Ford, J.G.2
Donaldson, D.D.3
-
50
-
-
0035424185
-
IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung
-
Mattes, J., Yang, M., Siqueira, A. et al. 2001. IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung. J. Immunol. 167:1683.
-
(2001)
J. Immunol.
, vol.167
, pp. 1683
-
-
Mattes, J.1
Yang, M.2
Siqueira, A.3
-
51
-
-
0037393502
-
Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro
-
Zheng, T., Zhu, Z., Liu, W. et al. 2003. Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro. J. Allergy Clin. Immunol. 111:720.
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 720
-
-
Zheng, T.1
Zhu, Z.2
Liu, W.3
-
52
-
-
0036884608
-
The role of IL-13 in established allergic airway disease
-
Taube, C., Duez, C., Cui, Z. H. et al. 2002. The role of IL-13 in established allergic airway disease. J. Immunol. 169:6482.
-
(2002)
J. Immunol.
, vol.169
, pp. 6482
-
-
Taube, C.1
Duez, C.2
Cui, Z.H.3
-
53
-
-
0344091551
-
Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2
-
Wood, N., Whitters, M. J., Jacobson, B. A. et al. 2003. Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. J. Exp. Med. 197:703.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 703
-
-
Wood, N.1
Whitters, M.J.2
Jacobson, B.A.3
-
54
-
-
0037451126
-
Decoy receptors in the regulation of T helper cell type 2 responses
-
McKenzie, A. N. and Fallon, P. G. 2003. Decoy receptors in the regulation of T helper cell type 2 responses. J. Exp. Med. 197:675.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 675
-
-
McKenzie, A.N.1
Fallon, P.G.2
-
55
-
-
0033768824
-
Identification and characterization of constitutively active Smad2 mutants: Evaluation of formation of Smad complex and subcellular distribution
-
Funaba, M. and Mathews, L. S. 2000. Identification and characterization of constitutively active Smad2 mutants: Evaluation of formation of Smad complex and subcellular distribution. Mol. Endocrinol. 14:1583.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1583
-
-
Funaba, M.1
Mathews, L.S.2
-
56
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling
-
Souchelnytskyi, S., Tamaki, K., Engstrom, U., Wernstedt, C., ten Dijke, P. and Heldin, C. H. 1997. Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling. J. Biol. Chem. 272:28107.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28107
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engstrom, U.3
Wernstedt, C.4
ten Dijke, P.5
Heldin, C.H.6
-
57
-
-
0033106484
-
A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras
-
Kretzschmar, M., Doody, J., Timokhina, I. and Massague, J. 1999. A mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev. 13:804.
-
(1999)
Genes Dev.
, vol.13
, pp. 804
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
58
-
-
0035827581
-
Functional characterization of transforming growth factor beta signaling in Smad2- and SMAD3-deficient fibroblasts
-
Piek, E., Ju, W. J., Heyer, J. et al. 2001. Functional characterization of transforming growth factor beta signaling in Smad2- and SMAD3-deficient fibroblasts. J. Biol. Chem. 276:19945.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19945
-
-
Piek, E.1
Ju, W.J.2
Heyer, J.3
-
59
-
-
3042550759
-
Targeted disruption of TGF-beta/SMAD3 signaling modulates skin fibrosis in a mouse model of scleroderma
-
Lakos, G., Takagawa, S., Chen, S. J. et al. 2004. Targeted disruption of TGF-beta/SMAD3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am. J. Pathol. 165:203.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 203
-
-
Lakos, G.1
Takagawa, S.2
Chen, S.J.3
-
60
-
-
10744233540
-
Interference with transforming growth factor-beta/ SMAD3 signaling results in accelerated healing of wounds in previously irradiated skin
-
Flanders, K. C., Major, C. D., Arabshahi, A. et al. 2003. Interference with transforming growth factor-beta/ SMAD3 signaling results in accelerated healing of wounds in previously irradiated skin. Am. J. Pathol. 163:2247.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2247
-
-
Flanders, K.C.1
Major, C.D.2
Arabshahi, A.3
-
61
-
-
19944427616
-
TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids
-
Tantisira, K. G., Hwang, E. S., Raby, B. A. et al. 2004. TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc. Natl Acad. Sci. USA 101: 18099.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 18099
-
-
Tantisira, K.G.1
Hwang, E.S.2
Raby, B.A.3
-
62
-
-
9144221958
-
Transforming growth factor-beta1 promoter polymorphism C-509T is associated with asthma
-
Silverman, E. S., Palmer, L. J., Subramaniam, V. et al. 2004. Transforming growth factor-beta1 promoter polymorphism C-509T is associated with asthma. Am. J. Respir. Crit. Care Med. 169:214.
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 214
-
-
Silverman, E.S.1
Palmer, L.J.2
Subramaniam, V.3
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