-
1
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003;4:337-342.
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
2
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003;4:330-336.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
3
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
4
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
5
-
-
0034052708
-
The self-directed T cell repertoire: Its creation and activation
-
Moudgil KD, Sercarz EE. The self-directed T cell repertoire: its creation and activation. Rev Immunogenet 2000;2:26-37.
-
(2000)
Rev Immunogenet
, vol.2
, pp. 26-37
-
-
Moudgil, K.D.1
Sercarz, E.E.2
-
6
-
-
0141790757
-
Lymphoid organ development and cell migration
-
Cyster JG. Lymphoid organ development and cell migration. Immunol Rev 2003;195:5-14.
-
(2003)
Immunol Rev
, vol.195
, pp. 5-14
-
-
Cyster, J.G.1
-
7
-
-
0042696999
-
Antigen presentation to naive CD4 T cells in the lymph node
-
Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nat Immunol 2003;4:733-739.
-
(2003)
Nat Immunol
, vol.4
, pp. 733-739
-
-
Itano, A.A.1
Jenkins, M.K.2
-
8
-
-
0037769037
-
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
-
Itano AA, et al. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity 2003;19:47-57.
-
(2003)
Immunity
, vol.19
, pp. 47-57
-
-
Itano, A.A.1
-
9
-
-
0037025990
-
Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice
-
Gagnerault MC, Luan JJ, Lotton C, Lepault F. Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice. J Exp Med 2002;196: 369-377.
-
(2002)
J Exp Med
, vol.196
, pp. 369-377
-
-
Gagnerault, M.C.1
Luan, J.J.2
Lotton, C.3
Lepault, F.4
-
10
-
-
9444242666
-
Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes
-
Levisetti MG, Suri A, Frederick K, Unanue ER. Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes. Diabetes 2004;53:3115-3119.
-
(2004)
Diabetes
, vol.53
, pp. 3115-3119
-
-
Levisetti, M.G.1
Suri, A.2
Frederick, K.3
Unanue, E.R.4
-
11
-
-
9644270396
-
Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells
-
Bour-Jordan H, Salomon BL, Thompson HL, Szot GL, Bernhard MR, Bluestone JA. Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. J Clin Invest 2004;114:979-987.
-
(2004)
J Clin Invest
, vol.114
, pp. 979-987
-
-
Bour-Jordan, H.1
Salomon, B.L.2
Thompson, H.L.3
Szot, G.L.4
Bernhard, M.R.5
Bluestone, J.A.6
-
12
-
-
4644335694
-
B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets
-
Yadav D, et al. B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets. J Immunol 2004;173:3631-3639.
-
(2004)
J Immunol
, vol.173
, pp. 3631-3639
-
-
Yadav, D.1
-
13
-
-
0042839568
-
Role of cytokines in the pathogenesis of autoimmune diabetes mellitus
-
Rabinovitch A, Suarez-Pinzon WL. Role of cytokines in the pathogenesis of autoimmune diabetes mellitus. Rev Endocr Metab Disord 2003;4:291-299.
-
(2003)
Rev Endocr Metab Disord
, vol.4
, pp. 291-299
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
14
-
-
13444261147
-
CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination
-
Segal BM. CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination. J Neurol Sci 2005;228:210-214.
-
(2005)
J Neurol Sci
, vol.228
, pp. 210-214
-
-
Segal, B.M.1
-
15
-
-
27144471025
-
Distinct effector mechanisms in the development of autoimmune neuropathy versus diabetes in nonobese diabetic mice
-
Bour-Jordan H, Thompson HL, Bluestone JA. Distinct effector mechanisms in the development of autoimmune neuropathy versus diabetes in nonobese diabetic mice. J Immunol 2005;175:5649-5655.
-
(2005)
J Immunol
, vol.175
, pp. 5649-5655
-
-
Bour-Jordan, H.1
Thompson, H.L.2
Bluestone, J.A.3
-
16
-
-
30044447736
-
Immune cell migration in inflammation: Present and future therapeutic targets
-
Luster AD, Alon R, von Andrian UH. Immune cell migration in inflammation: present and future therapeutic targets. Nat Immunol 2005;6:1182-1190.
-
(2005)
Nat Immunol
, vol.6
, pp. 1182-1190
-
-
Luster, A.D.1
Alon, R.2
Von Andrian, U.H.3
-
17
-
-
14544300428
-
Selective generation of gut-tropic T cells in gut-associated lymphoid tissues: Requirement for GALT dendritic cells and adjuvant
-
Svensson M, Johansson-Lindbom B, Wurbel MA, Malissen B, Marquez G, Agace W. Selective generation of gut-tropic T cells in gut-associated lymphoid tissues: requirement for GALT dendritic cells and adjuvant. Ann NY Acad Sci 2004;1029:405-407.
-
(2004)
Ann NY Acad Sci
, vol.1029
, pp. 405-407
-
-
Svensson, M.1
Johansson-Lindbom, B.2
Wurbel, M.A.3
Malissen, B.4
Marquez, G.5
Agace, W.6
-
18
-
-
0141449950
-
Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): Requirement for GALT dendritic cells and adjuvant
-
Johansson-Lindbom B, Svensson M, Wurbel MA, Malissen B, Marquez G, Agace W. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 2003;198:963-969.
-
(2003)
J Exp Med
, vol.198
, pp. 963-969
-
-
Johansson-Lindbom, B.1
Svensson, M.2
Wurbel, M.A.3
Malissen, B.4
Marquez, G.5
Agace, W.6
-
19
-
-
0038264036
-
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
-
Mora JR, et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003;424:88-93.
-
(2003)
Nature
, vol.424
, pp. 88-93
-
-
Mora, J.R.1
-
20
-
-
17144398284
-
Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: Important roles for soluble factors and tissue microenvironments
-
Dudda JC, et al. Dendritic cells govern induction and reprogramming of polarized tissue-selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments. Eur J Immunol 2005;35:1056-1065.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1056-1065
-
-
Dudda, J.C.1
-
21
-
-
0031441873
-
The roles of alpha 4-integrins in the development of insulin-dependent diabetes mellitus
-
Michie SA, Sytwu HK, McDevitt JO, Yang XD. The roles of alpha 4-integrins in the development of insulin-dependent diabetes mellitus. Curr Top Microbiol Immunol 1998;231:65-83.
-
(1998)
Curr Top Microbiol Immunol
, vol.231
, pp. 65-83
-
-
Michie, S.A.1
Sytwu, H.K.2
McDevitt, J.O.3
Yang, X.D.4
-
22
-
-
0037087405
-
L-selectin is not required for T cell-mediated autoimmune diabetes
-
Friedline RH, Wong CP, Steeber DA, Tedder TF, Tisch R. L-selectin is not required for T cell-mediated autoimmune diabetes. J Immunol 2002;168:2659-2666.
-
(2002)
J Immunol
, vol.168
, pp. 2659-2666
-
-
Friedline, R.H.1
Wong, C.P.2
Steeber, D.A.3
Tedder, T.F.4
Tisch, R.5
-
23
-
-
1042269481
-
Role of L-selectin in the development of autoimmune diabetes in non-obese diabetic mice
-
Mora C, Grewal IS, Wong FS, Flavell RA. Role of L-selectin in the development of autoimmune diabetes in non-obese diabetic mice. Int Immunol 2004;16:257-264.
-
(2004)
Int Immunol
, vol.16
, pp. 257-264
-
-
Mora, C.1
Grewal, I.S.2
Wong, F.S.3
Flavell, R.A.4
-
24
-
-
0036896022
-
CCR4-bearing T cells participate in autoimmune diabetes
-
Kim SH, Cleary MM, Fox HS, Chantry D, Sarvetnick N. CCR4-bearing T cells participate in autoimmune diabetes. J Clin Invest 2002;110:1675-1686.
-
(2002)
J Clin Invest
, vol.110
, pp. 1675-1686
-
-
Kim, S.H.1
Cleary, M.M.2
Fox, H.S.3
Chantry, D.4
Sarvetnick, N.5
-
25
-
-
0036913215
-
Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
-
Frigerio S, et al. Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med 2002;8:1414-1420.
-
(2002)
Nat Med
, vol.8
, pp. 1414-1420
-
-
Frigerio, S.1
-
26
-
-
16244417773
-
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
-
McMahon EJ, Bailey SL, Castenada CV, Waldner H, Miller SD. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 2005;11:335-339.
-
(2005)
Nat Med
, vol.11
, pp. 335-339
-
-
McMahon, E.J.1
Bailey, S.L.2
Castenada, C.V.3
Waldner, H.4
Miller, S.D.5
-
27
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter M, et al. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med 2005;11:328-334.
-
(2005)
Nat Med
, vol.11
, pp. 328-334
-
-
Greter, M.1
-
28
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner FL, et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med 2005;11:146-152.
-
(2005)
Nat Med
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
-
29
-
-
0034026665
-
In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis
-
Shinomiya M, Nadano S, Shinomiya H, Onji M. In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis. Pancreas 2000;20:290-296.
-
(2000)
Pancreas
, vol.20
, pp. 290-296
-
-
Shinomiya, M.1
Nadano, S.2
Shinomiya, H.3
Onji, M.4
-
30
-
-
3843080902
-
Increased islet antigen presentation leads to type-1 diabetes in mice with autoimmune susceptibility
-
Judkowski V, Krakowski M, Rodriguez E, Mocnick L, Santamaria P, Sarvetnick N. Increased islet antigen presentation leads to type-1 diabetes in mice with autoimmune susceptibility. Eur J Immunol 2004;34:1031-1040.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1031-1040
-
-
Judkowski, V.1
Krakowski, M.2
Rodriguez, E.3
Mocnick, L.4
Santamaria, P.5
Sarvetnick, N.6
-
31
-
-
17144418467
-
Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri) -insulitis of the nonobese diabetic mouse: A phagocyte depletion study
-
Nikolic T, Geutskens SB, van Rooijen N, Drexhage HA, Leenen PJ. Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri) -insulitis of the nonobese diabetic mouse: a phagocyte depletion study. Lab Invest 2005;85:487-501.
-
(2005)
Lab Invest
, vol.85
, pp. 487-501
-
-
Nikolic, T.1
Geutskens, S.B.2
Van Rooijen, N.3
Drexhage, H.A.4
Leenen, P.J.5
-
32
-
-
0345448056
-
Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
-
Turley S, Poirot L, Hattori M, Benoist C, Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J Exp Med 2003;198:1527-1537.
-
(2003)
J Exp Med
, vol.198
, pp. 1527-1537
-
-
Turley, S.1
Poirot, L.2
Hattori, M.3
Benoist, C.4
Mathis, D.5
-
33
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 2000;12:431-440.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
34
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 2005;201:723-735.
-
(2005)
J Exp Med
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
35
-
-
2942692037
-
CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
-
Herman AE, Freeman GJ, Mathis D, Benoist C. CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med 2004;199:1479-1489.
-
(2004)
J Exp Med
, vol.199
, pp. 1479-1489
-
-
Herman, A.E.1
Freeman, G.J.2
Mathis, D.3
Benoist, C.4
-
36
-
-
0035198718
-
Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes
-
Gonzalez A, Andre-Schmutz I, Carnaud C, Mathis D, Benoist C. Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes. Nat Immunol 2001;2:1117-1125.
-
(2001)
Nat Immunol
, vol.2
, pp. 1117-1125
-
-
Gonzalez, A.1
Andre-Schmutz, I.2
Carnaud, C.3
Mathis, D.4
Benoist, C.5
-
37
-
-
27944454429
-
Where CD4+CD25+ T reg cells impinge on autoimmune diabetes
-
Chen Z, Herman AE, Matos M, Mathis D, Benoist C. Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. J Exp Med 2005;202:1387-1397.
-
(2005)
J Exp Med
, vol.202
, pp. 1387-1397
-
-
Chen, Z.1
Herman, A.E.2
Matos, M.3
Mathis, D.4
Benoist, C.5
-
38
-
-
20944444896
-
Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells
-
You S, et al. Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes 2005;54:1415-1422.
-
(2005)
Diabetes
, vol.54
, pp. 1415-1422
-
-
You, S.1
-
39
-
-
18244400088
-
Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes
-
Pop SM, Wong CP, Culton DA, Clarke SH, Tisch R. Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. J Exp Med 2005;201:1333-1346.
-
(2005)
J Exp Med
, vol.201
, pp. 1333-1346
-
-
Pop, S.M.1
Wong, C.P.2
Culton, D.A.3
Clarke, S.H.4
Tisch, R.5
-
40
-
-
0141992907
-
Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development
-
Gregori S, Giarratana N, Smiroldo S, Adorini L. Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development. J Immunol 2003;171:4040-4047.
-
(2003)
J Immunol
, vol.171
, pp. 4040-4047
-
-
Gregori, S.1
Giarratana, N.2
Smiroldo, S.3
Adorini, L.4
-
41
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja A, et al. Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest 2002;109:131-140.
-
(2002)
J Clin Invest
, vol.109
, pp. 131-140
-
-
Kukreja, A.1
-
42
-
-
12144249838
-
Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
-
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI. Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes. Diabetes 2005;54:92-99.
-
(2005)
Diabetes
, vol.54
, pp. 92-99
-
-
Lindley, S.1
Dayan, C.M.2
Bishop, A.3
Roep, B.O.4
Peakman, M.5
Tree, T.I.6
-
43
-
-
17844364504
-
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes
-
Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes. Diabetes 2005;54:1407-1414.
-
(2005)
Diabetes
, vol.54
, pp. 1407-1414
-
-
Brusko, T.M.1
Wasserfall, C.H.2
Clare-Salzler, M.J.3
Schatz, D.A.4
Atkinson, M.A.5
-
45
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004;199:971-979.
-
(2004)
J Exp Med
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
46
-
-
1842607712
-
Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs
-
Putheti P, Pettersson A, Soderstrom M, Link H, Huang YM. Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs. J Clin Immunol 2004;24:155-161.
-
(2004)
J Clin Immunol
, vol.24
, pp. 155-161
-
-
Putheti, P.1
Pettersson, A.2
Soderstrom, M.3
Link, H.4
Huang, Y.M.5
-
47
-
-
21044449573
-
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells
-
Ochando JC, et al. Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. J Immunol 2005;174:6993-7005.
-
(2005)
J Immunol
, vol.174
, pp. 6993-7005
-
-
Ochando, J.C.1
-
48
-
-
0037083360
-
L-selectin-dependent lymphoid occupancy is required to induce alloantigen-specific tolerance
-
Bai Y, et al. L-selectin-dependent lymphoid occupancy is required to induce alloantigen-specific tolerance. J Immunol 2002;168:1579-1589.
-
(2002)
J Immunol
, vol.168
, pp. 1579-1589
-
-
Bai, Y.1
-
49
-
-
17144374934
-
Regulatory T-cell therapy: Is it ready for the clinic?
-
Bluestone JA. Regulatory T-cell therapy: is it ready for the clinic? Nat Rev Immunol 2005;5:343-349.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 343-349
-
-
Bluestone, J.A.1
-
50
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang Q, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 2006;7:83-92.
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
-
52
-
-
27144524938
-
Migration matters: Regulatory T cell compartmentalization determines suppressive activity in vivo
-
Siegmund K, et al. Migration matters: regulatory T cell compartmentalization determines suppressive activity in vivo. Blood 2005;106:3097-3104.
-
(2005)
Blood
, vol.106
, pp. 3097-3104
-
-
Siegmund, K.1
-
53
-
-
0037097503
-
Cutting edge: Depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
-
McHugh RS, Shevach EM. Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J Immunol 2002;168:5979-5983.
-
(2002)
J Immunol
, vol.168
, pp. 5979-5983
-
-
McHugh, R.S.1
Shevach, E.M.2
-
54
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
USA
-
Chen ML, et al. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci USA 2005;102:419-424.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 419-424
-
-
Chen, M.L.1
-
55
-
-
4344657757
-
CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
-
Sarween N, Chodos A, Raykundalia C, Khan M, Abbas AK, Walker LS. CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol 2004;173:2942-2951.
-
(2004)
J Immunol
, vol.173
, pp. 2942-2951
-
-
Sarween, N.1
Chodos, A.2
Raykundalia, C.3
Khan, M.4
Abbas, A.K.5
Walker, L.S.6
-
56
-
-
0037810672
-
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens
-
Lohr J, Knoechel B, Jiang S, Sharpe AH, Abbas AK. The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol 2003;4:664-669.
-
(2003)
Nat Immunol
, vol.4
, pp. 664-669
-
-
Lohr, J.1
Knoechel, B.2
Jiang, S.3
Sharpe, A.H.4
Abbas, A.K.5
-
57
-
-
2442637772
-
Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
-
Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J Immunol 2004;172:6519-6523.
-
(2004)
J Immunol
, vol.172
, pp. 6519-6523
-
-
Thornton, A.M.1
Donovan, E.E.2
Piccirillo, C.A.3
Shevach, E.M.4
-
58
-
-
1642390941
-
Activation requirements for the induction of CD4+CD25+ T cell suppressor function
-
Thornton AM, Piccirillo CA, Shevach EM. Activation requirements for the induction of CD4+CD25+ T cell suppressor function. Eur J Immunol 2004;34:366-376.
-
(2004)
Eur J Immunol
, vol.34
, pp. 366-376
-
-
Thornton, A.M.1
Piccirillo, C.A.2
Shevach, E.M.3
-
59
-
-
0242494202
-
Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes
-
Masteller EL, et al. Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes. J Immunol 2003;171:5587-5595.
-
(2003)
J Immunol
, vol.171
, pp. 5587-5595
-
-
Masteller, E.L.1
-
60
-
-
0037290768
-
Epitope dominance, competition and T cell affinity maturation
-
Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Curr Opin Immunol 2003;15:120-127.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 120-127
-
-
Kedl, R.M.1
Kappler, J.W.2
Marrack, P.3
-
61
-
-
0033565272
-
Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens
-
Morgan DJ, Kreuwel HT, Sherman LA. Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens. J Immunol 1999;163:723-727.
-
(1999)
J Immunol
, vol.163
, pp. 723-727
-
-
Morgan, D.J.1
Kreuwel, H.T.2
Sherman, L.A.3
-
62
-
-
23944461953
-
Initial T cell frequency dictates memory CD8+ T cell lineage commitment
-
Marzo AL, Klonowski KD, Le Bon A, Borrow P, Tough DF, Lefrancois L. Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nat Immunol 2005;6:793-799.
-
(2005)
Nat Immunol
, vol.6
, pp. 793-799
-
-
Marzo, A.L.1
Klonowski, K.D.2
Le Bon, A.3
Borrow, P.4
Tough, D.F.5
Lefrancois, L.6
-
63
-
-
20344392877
-
Migration rules: Functional properties of naive and effector/memory-like regulatory T cell subsets
-
Huehn J, Siegmund K, Hamann A. Migration rules: functional properties of naive and effector/memory-like regulatory T cell subsets. Curr Top Microbiol Immunol 2005;293:89-114.
-
(2005)
Curr Top Microbiol Immunol
, vol.293
, pp. 89-114
-
-
Huehn, J.1
Siegmund, K.2
Hamann, A.3
-
64
-
-
0037124359
-
Identification of regulatory T cells in tolerated allografts
-
Graca L, Cobbold SP, Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med 2002;195:1641-1646.
-
(2002)
J Exp Med
, vol.195
, pp. 1641-1646
-
-
Graca, L.1
Cobbold, S.P.2
Waldmann, H.3
-
65
-
-
15444377017
-
Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
-
Yu P, et al. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J Exp Med 2005;201:779-791.
-
(2005)
J Exp Med
, vol.201
, pp. 779-791
-
-
Yu, P.1
-
66
-
-
17144393320
-
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
-
Lee I, Wang L, Wells AD, Dorf ME, Ozkaynak E, Hancock WW. Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med 2005;201:1037-1044.
-
(2005)
J Exp Med
, vol.201
, pp. 1037-1044
-
-
Lee, I.1
Wang, L.2
Wells, A.D.3
Dorf, M.E.4
Ozkaynak, E.5
Hancock, W.W.6
-
67
-
-
28244444532
-
Messenger RNA for FOXP3 in the urine of renal-allograft recipients
-
Muthukumar T, et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med 2005;353:2342-2351.
-
(2005)
N Engl J Med
, vol.353
, pp. 2342-2351
-
-
Muthukumar, T.1
-
68
-
-
0028874330
-
Molecular analysis of TCR junctional variability in individual infiltrated islets of non-obese diabetic mice: Evidence for the constitution of largely autonomous T cell foci within the same pancreas
-
Sarukhan A, Bedossa P, Garchon HJ, Bach JF, Carnaud C. Molecular analysis of TCR junctional variability in individual infiltrated islets of non-obese diabetic mice: evidence for the constitution of largely autonomous T cell foci within the same pancreas. Int Immunol 1995;7:139-146.
-
(1995)
Int Immunol
, vol.7
, pp. 139-146
-
-
Sarukhan, A.1
Bedossa, P.2
Garchon, H.J.3
Bach, J.F.4
Carnaud, C.5
-
69
-
-
1942539173
-
Kinetic evolution of a diabetogenic CD8+ T cell response
-
Santamaria P. Kinetic evolution of a diabetogenic CD8+ T cell response. Ann NY Acad Sci 2003;1005:88-97.
-
(2003)
Ann NY Acad Sci
, vol.1005
, pp. 88-97
-
-
Santamaria, P.1
-
70
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003;299:1033-1036.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
71
-
-
22344432319
-
Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
-
Ruprecht CR, et al. Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. J Exp Med 2005;201:1793-1803.
-
(2005)
J Exp Med
, vol.201
, pp. 1793-1803
-
-
Ruprecht, C.R.1
-
72
-
-
23244443617
-
Cutting edge: IL-12 induces CD4+CD25- T cell activation in the presence of T regulatory cells
-
King IL, Segal BM. Cutting edge: IL-12 induces CD4+CD25- T cell activation in the presence of T regulatory cells. J Immunol 2005;175:641-645.
-
(2005)
J Immunol
, vol.175
, pp. 641-645
-
-
King, I.L.1
Segal, B.M.2
-
73
-
-
0032759199
-
The interplay between the duration of TCR and cytokine signaling determines T cell polarization
-
Iezzi G, Scotet E, Scheidegger D, Lanzavecchia A. The interplay between the duration of TCR and cytokine signaling determines T cell polarization. Eur J Immunol 1999;29:4092-4101.
-
(1999)
Eur J Immunol
, vol.29
, pp. 4092-4101
-
-
Iezzi, G.1
Scotet, E.2
Scheidegger, D.3
Lanzavecchia, A.4
-
75
-
-
0041695164
-
Continuous T cell receptor signaling required for synapse maintenance and full effector potential
-
Huppa JB, Gleimer M, Sumen C, Davis MM. Continuous T cell receptor signaling required for synapse maintenance and full effector potential. Nat Immunol 2003;4:749-755.
-
(2003)
Nat Immunol
, vol.4
, pp. 749-755
-
-
Huppa, J.B.1
Gleimer, M.2
Sumen, C.3
Davis, M.M.4
-
76
-
-
0037036114
-
Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
-
Stoll S, Delon J, Brotz TM, Germain RN. Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 2002;296:1873-1876.
-
(2002)
Science
, vol.296
, pp. 1873-1876
-
-
Stoll, S.1
Delon, J.2
Brotz, T.M.3
Germain, R.N.4
-
77
-
-
0347717903
-
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
-
Mempel TR, Henrickson SE, Von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 2004;427:154-159.
-
(2004)
Nature
, vol.427
, pp. 154-159
-
-
Mempel, T.R.1
Henrickson, S.E.2
Von Andrian, U.H.3
-
78
-
-
0037036142
-
Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
-
Miller MJ, Wei SH, Parker I, Cahalan MD. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 2002;296:1869-1873.
-
(2002)
Science
, vol.296
, pp. 1869-1873
-
-
Miller, M.J.1
Wei, S.H.2
Parker, I.3
Cahalan, M.D.4
-
79
-
-
5444229324
-
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes
-
Miller MJ, Safrina O, Parker I, Cahalan MD. Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med 2004;200:847-856.
-
(2004)
J Exp Med
, vol.200
, pp. 847-856
-
-
Miller, M.J.1
Safrina, O.2
Parker, I.3
Cahalan, M.D.4
-
80
-
-
0037501371
-
Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes
-
Bousso P, Robey E. Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nat Immunol 2003;4:579-585.
-
(2003)
Nat Immunol
, vol.4
, pp. 579-585
-
-
Bousso, P.1
Robey, E.2
-
81
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4 (+) CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4 (+) CD25 (+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 2001;194:629-644.
-
(2001)
J Exp Med
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
82
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
USA
-
Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci USA 2004;101:10398-10403.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
83
-
-
5644302161
-
Human T regulatory cells can use the perform pathway to cause autologous target cell death
-
Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ. Human T regulatory cells can use the perform pathway to cause autologous target cell death. Immunity 2004;21:589-601.
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
84
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999;190:995-1004.
-
(1999)
J Exp Med
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
85
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
86
-
-
0036467522
-
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
Kingsley CI, Karim M, Bushell AR, Wood KJ. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002;168:1080-1086.
-
(2002)
J Immunol
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
87
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 2002;420:502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
88
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki S, et al. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med 2003;198:235-247.
-
(2003)
J Exp Med
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
-
89
-
-
10344233176
-
Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
-
Kubo T, Hatton RD, Oliver J, Liu X, Elson CO, Weaver CT. Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J Immunol 2004;173:7249-7258.
-
(2004)
J Immunol
, vol.173
, pp. 7249-7258
-
-
Kubo, T.1
Hatton, R.D.2
Oliver, J.3
Liu, X.4
Elson, C.O.5
Weaver, C.T.6
-
90
-
-
12144270876
-
Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4(+)CD25(+) regulatory T-cells
-
Kared H, Masson A, Adle-Biassette H, Bach JF, Chatenoud L, Zavala F. Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4(+)CD25(+) regulatory T-cells. Diabetes 2005;54:78-84.
-
(2005)
Diabetes
, vol.54
, pp. 78-84
-
-
Kared, H.1
Masson, A.2
Adle-Biassette, H.3
Bach, J.F.4
Chatenoud, L.5
Zavala, F.6
-
91
-
-
0037391351
-
Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties
-
Bilsborough J, George TC, Norment A, Viney JL. Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology 2003;108:481-492.
-
(2003)
Immunology
, vol.108
, pp. 481-492
-
-
Bilsborough, J.1
George, T.C.2
Norment, A.3
Viney, J.L.4
-
92
-
-
14044278784
-
Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function
-
Cong Y, Konrad A, Iqbal N, Hatton RD, Weaver CT, Elson CO. Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function. J Immunol 2005;174:2787-2795.
-
(2005)
J Immunol
, vol.174
, pp. 2787-2795
-
-
Cong, Y.1
Konrad, A.2
Iqbal, N.3
Hatton, R.D.4
Weaver, C.T.5
Elson, C.O.6
-
93
-
-
33644691658
-
On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes
-
Bruder D, et al. On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes. Diabetes 2005;54:3395-3401.
-
(2005)
Diabetes
, vol.54
, pp. 3395-3401
-
-
Bruder, D.1
-
94
-
-
0043244853
-
CD4+ CD25+ regulatory T cells control T helper cell type 1 responses to foreign antigens induced by mature dendritic cells in vivo
-
Oldenhove G, et al. CD4+ CD25+ regulatory T cells control T helper cell type 1 responses to foreign antigens induced by mature dendritic cells in vivo. J Exp Med 2003;198:259-266.
-
(2003)
J Exp Med
, vol.198
, pp. 259-266
-
-
Oldenhove, G.1
-
95
-
-
0034077559
-
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
-
Cederbom L, Hall H, Ivars F. CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 2000;30:1538-1543.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1538-1543
-
-
Cederbom, L.1
Hall, H.2
Ivars, F.3
-
96
-
-
0347480215
-
CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells
-
Serra P, et al. CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. Immunity 2003;19:877-889.
-
(2003)
Immunity
, vol.19
, pp. 877-889
-
-
Serra, P.1
-
97
-
-
1842581857
-
Cutting edge, human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
-
Misra N, Bayry J, Lacroix-Desmazes S, Kazatchkine MD, Kaveri SV. Cutting edge, human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J Immunol 2004;172:4676-4680.
-
(2004)
J Immunol
, vol.172
, pp. 4676-4680
-
-
Misra, N.1
Bayry, J.2
Lacroix-Desmazes, S.3
Kazatchkine, M.D.4
Kaveri, S.V.5
-
98
-
-
15444365238
-
Downregulation of IL-12 and a novel negative feedback system mediated by CD25+CD4+ T cells
-
Sato K, Tateishi S, Kubo K, Mimura T, Yamamoto K, Kanda H. Downregulation of IL-12 and a novel negative feedback system mediated by CD25+CD4+ T cells. Biochem Biophys Res Commun 2005;330:226-232.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 226-232
-
-
Sato, K.1
Tateishi, S.2
Kubo, K.3
Mimura, T.4
Yamamoto, K.5
Kanda, H.6
-
99
-
-
28544432829
-
CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function
-
Lewkowich IP, et al. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J Exp Med 2005;202:1549-1561.
-
(2005)
J Exp Med
, vol.202
, pp. 1549-1561
-
-
Lewkowich, I.P.1
-
100
-
-
17144367365
-
In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma
-
van Rijt LS, et al. In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med 2005;201:981-991.
-
(2005)
J Exp Med
, vol.201
, pp. 981-991
-
-
Van Rijt, L.S.1
-
101
-
-
0020451946
-
Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
-
Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J Exp Med 1982;156:1577-1586.
-
(1982)
J Exp Med
, vol.156
, pp. 1577-1586
-
-
Sakaguchi, S.1
Takahashi, T.2
Nishizuka, Y.3
-
102
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000;101:455-458.
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
103
-
-
0032403697
-
Control of immune pathology by regulatory T cells
-
Mason D, Powrie F. Control of immune pathology by regulatory T cells. Curr Opin Immunol 1998;10:649-655.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 649-655
-
-
Mason, D.1
Powrie, F.2
-
105
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q, et al. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 2004;199:1455-1465.
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
-
106
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single auto-antigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single auto-antigenic peptide, suppress autoimmune diabetes. J Exp Med 2004;199:1467-1477.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
107
-
-
1042269477
-
IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells
-
Zhang X, et al. IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells. Int Immunol 2004;16:249-256.
-
(2004)
Int Immunol
, vol.16
, pp. 249-256
-
-
Zhang, X.1
-
108
-
-
0036838536
-
Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
-
Kohm AP, Carpentier PA, Anger HA, Miller SD. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J Immunol 2002;169:4712-4716.
-
(2002)
J Immunol
, vol.169
, pp. 4712-4716
-
-
Kohm, A.P.1
Carpentier, P.A.2
Anger, H.A.3
Miller, S.D.4
-
109
-
-
0141461418
-
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
-
Edinger M, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med 2003;9:1144-1150.
-
(2003)
Nat Med
, vol.9
, pp. 1144-1150
-
-
Edinger, M.1
-
110
-
-
0346690399
-
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
Trenado A, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest 2003;112:1688-1696.
-
(2003)
J Clin Invest
, vol.112
, pp. 1688-1696
-
-
Trenado, A.1
-
111
-
-
0037093217
-
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
-
Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002;99:3493-3499.
-
(2002)
Blood
, vol.99
, pp. 3493-3499
-
-
Taylor, P.A.1
Lees, C.J.2
Blazar, B.R.3
-
112
-
-
20144370643
-
The role of regulatory T cells in antigen-induced arthritis: Aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells
-
Frey O, et al. The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells. Arthritis Res Ther 2005;7:R291-R301.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Frey, O.1
-
113
-
-
0034967640
-
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells
-
Suri-Payer E, Cantor H. Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun 2001;16:115-123.
-
(2001)
J Autoimmun
, vol.16
, pp. 115-123
-
-
Suri-Payer, E.1
Cantor, H.2
-
114
-
-
28244447468
-
CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells
-
DiPaolo RJ, Glass DD, Bijwaard KE, Shevach EM. CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells. J Immunol 2005;175:7135-7142.
-
(2005)
J Immunol
, vol.175
, pp. 7135-7142
-
-
DiPaolo, R.J.1
Glass, D.D.2
Bijwaard, K.E.3
Shevach, E.M.4
-
115
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
116
-
-
33746355344
-
Suppression of disease in NZB/NZW lupus prone mice by adoptive transfer of ex vivo expanded regulatory T cells
-
in press
-
Scalapino KJ, Tang Q, Bluestone JA, Bonyhadi ML, Daikh DI. Suppression of disease in NZB/NZW lupus prone mice by adoptive transfer of ex vivo expanded regulatory T cells. J Immunol (in press).
-
J Immunol
-
-
Scalapino, K.J.1
Tang, Q.2
Bluestone, J.A.3
Bonyhadi, M.L.4
Daikh, D.I.5
-
117
-
-
20344365312
-
Autoimmune ovarian disease in day 3-thymectomized mice: The neonatal time window, antigen specificity of disease suppression, and genetic control
-
Tung KS, Setiady YY, Samy ET, Lewis J, Teuscher C. Autoimmune ovarian disease in day 3-thymectomized mice: the neonatal time window, antigen specificity of disease suppression, and genetic control. Curr Top Microbiol Immunol 2005;293:209-247.
-
(2005)
Curr Top Microbiol Immunol
, vol.293
, pp. 209-247
-
-
Tung, K.S.1
Setiady, Y.Y.2
Samy, E.T.3
Lewis, J.4
Teuscher, C.5
-
119
-
-
0015172562
-
Infectious immunological tolerance
-
Gershon RK, Kondo K. Infectious immunological tolerance. Immunology 1971;21:903-914.
-
(1971)
Immunology
, vol.21
, pp. 903-914
-
-
Gershon, R.K.1
Kondo, K.2
-
120
-
-
30744461834
-
Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells
-
Trenado A, et al. Ex vivo-expanded CD4+CD25+ immunoregulatory T cells prevent graft-versus-host-disease by inhibiting activation/differentiation of pathogenic T cells. J Immunol 2006;176:1266-1273.
-
(2006)
J Immunol
, vol.176
, pp. 1266-1273
-
-
Trenado, A.1
-
121
-
-
1642494602
-
Ex vivo selection of recipient-type alloantigen-specific CD4(+)CD25(+) immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation
-
Trenado A, Fisson S, Braunberger E, Klatzmann D, Salomon BL, Cohen JL. Ex vivo selection of recipient-type alloantigen-specific CD4(+)CD25(+) immunoregulatory T cells for the control of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation. Transplantation 2004;77:S32-S34.
-
(2004)
Transplantation
, vol.77
-
-
Trenado, A.1
Fisson, S.2
Braunberger, E.3
Klatzmann, D.4
Salomon, B.L.5
Cohen, J.L.6
-
122
-
-
0035554674
-
T cell regulation: A special job or everyone's responsibility?
-
Stockinger B, Barthlott T, Kassiotis G. T cell regulation: a special job or everyone's responsibility? Nat Immunol 2001;2:757-758.
-
(2001)
Nat Immunol
, vol.2
, pp. 757-758
-
-
Stockinger, B.1
Barthlott, T.2
Kassiotis, G.3
-
123
-
-
0037450727
-
T cell regulation as a side effect of homeostasis and competition
-
Barthlott T, Kassiotis G, Stockinger B. T cell regulation as a side effect of homeostasis and competition. J Exp Med 2003;197:451-460.
-
(2003)
J Exp Med
, vol.197
, pp. 451-460
-
-
Barthlott, T.1
Kassiotis, G.2
Stockinger, B.3
-
124
-
-
0035863825
-
Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question
-
Suchin EJ, Langmuir PB, Palmer E, Sayegh MH, Wells AD, Turka LA. Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question. J Immunol 2001;166:973-981.
-
(2001)
J Immunol
, vol.166
, pp. 973-981
-
-
Suchin, E.J.1
Langmuir, P.B.2
Palmer, E.3
Sayegh, M.H.4
Wells, A.D.5
Turka, L.A.6
-
125
-
-
0034992147
-
Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset
-
Novak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT. Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset. Int Immunol 2001;13:799-806.
-
(2001)
Int Immunol
, vol.13
, pp. 799-806
-
-
Novak, E.J.1
Masewicz, S.A.2
Liu, A.W.3
Lernmark, A.4
Kwok, W.W.5
Nepom, G.T.6
-
126
-
-
13544258633
-
Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation
-
Hanash AM, Levy RB. Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. Blood 2005;105:1828-1836.
-
(2005)
Blood
, vol.105
, pp. 1828-1836
-
-
Hanash, A.M.1
Levy, R.B.2
-
127
-
-
0033985780
-
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
-
Thornton AM, Shevach EM. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 2000;164:183-190.
-
(2000)
J Immunol
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
128
-
-
0242486680
-
CD4+CD25+ regulatory T cells generated in response to insulin B: 9-23 Peptide prevent adoptive transfer of diabetes by diabetogenic T cells
-
Mukherjee R, Chaturvedi P, Qin HY, Singh B. CD4+CD25+ regulatory T cells generated in response to insulin B: 9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells. J Autoimmun 2003;21:221-237.
-
(2003)
J Autoimmun
, vol.21
, pp. 221-237
-
-
Mukherjee, R.1
Chaturvedi, P.2
Qin, H.Y.3
Singh, B.4
-
129
-
-
0036196305
-
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
-
Green EA, Choi Y, Flavell RA. Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity 2002;16:183-191.
-
(2002)
Immunity
, vol.16
, pp. 183-191
-
-
Green, E.A.1
Choi, Y.2
Flavell, R.A.3
-
130
-
-
0033103668
-
Peripheral autoantigen induces regulatory T cells that prevent autoimmunity
-
Seddon B, Mason D. Peripheral autoantigen induces regulatory T cells that prevent autoimmunity. J Exp Med 1999;189:877-882.
-
(1999)
J Exp Med
, vol.189
, pp. 877-882
-
-
Seddon, B.1
Mason, D.2
-
131
-
-
0033853625
-
Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
-
Kuniyasu Y, Takahashi T, Itoh M, Shimizu J, Toda G, Sakaguchi S. Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol 2000;12:1145-1155.
-
(2000)
Int Immunol
, vol.12
, pp. 1145-1155
-
-
Kuniyasu, Y.1
Takahashi, T.2
Itoh, M.3
Shimizu, J.4
Toda, G.5
Sakaguchi, S.6
-
132
-
-
0032169512
-
Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate 'active tolerance' in the nonobese diabetic mouse
-
Herbelin A, Gombert JM, Lepault F, Bach JF, Chatenoud L. Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate 'active tolerance' in the nonobese diabetic mouse. J Immunol 1998;161:2620-2628.
-
(1998)
J Immunol
, vol.161
, pp. 2620-2628
-
-
Herbelin, A.1
Gombert, J.M.2
Lepault, F.3
Bach, J.F.4
Chatenoud, L.5
-
133
-
-
0033970953
-
Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice
-
Lepault F, Gagnerault MC. Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice. J Immunol 2000;164:240-247.
-
(2000)
J Immunol
, vol.164
, pp. 240-247
-
-
Lepault, F.1
Gagnerault, M.C.2
-
134
-
-
10744221289
-
Developmental stage, phenotype, and migration distinguish naive-and effector/memory-like CD4+ regulatory T cells
-
Huehn J, et al. Developmental stage, phenotype, and migration distinguish naive-and effector/memory-like CD4+ regulatory T cells. J Exp Med 2004;199:303-313.
-
(2004)
J Exp Med
, vol.199
, pp. 303-313
-
-
Huehn, J.1
-
135
-
-
30444458396
-
Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44
-
Firan M, Dhillon S, Estess P, Siegeknan MH. Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44. Blood 2006;107:619-627.
-
(2006)
Blood
, vol.107
, pp. 619-627
-
-
Firan, M.1
Dhillon, S.2
Estess, P.3
Siegeknan, M.H.4
-
136
-
-
0346103659
-
Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases
-
USA
-
Alyanakian MA, et al. Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases. Proc Natl Acad Sci USA 2003;100:15806-15811.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 15806-15811
-
-
Alyanakian, M.A.1
-
137
-
-
13544271155
-
CCR8 is expressed by antigen-elicited, IL-10-producing CD4+CD25+ T cells, which regulate Th2-mediated granuloma formation in mice
-
Freeman CM, et al. CCR8 is expressed by antigen-elicited, IL-10-producing CD4+CD25+ T cells, which regulate Th2-mediated granuloma formation in mice. J Immunol 2005;174:1962-1970.
-
(2005)
J Immunol
, vol.174
, pp. 1962-1970
-
-
Freeman, C.M.1
-
138
-
-
0035903307
-
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells
-
Iellem A, et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med 2001;194:847-853.
-
(2001)
J Exp Med
, vol.194
, pp. 847-853
-
-
Iellem, A.1
-
139
-
-
15944425718
-
CCR6 expression defines regulatory effector/memory-like cells within the CD25 (+) CD4+ T-cell subset
-
Kleinewietfeld M, Puentes F, Borsellino G, Battistini L, Rotzschke O, Falk K. CCR6 expression defines regulatory effector/memory-like cells within the CD25 (+) CD4+ T-cell subset. Blood 2005;105:2877-2886.
-
(2005)
Blood
, vol.105
, pp. 2877-2886
-
-
Kleinewietfeld, M.1
Puentes, F.2
Borsellino, G.3
Battistini, L.4
Rotzschke, O.5
Falk, K.6
-
140
-
-
10044293050
-
Pregnancy-induced expansion of regulatory T-lymphocytes may mediate protection to multiple sclerosis activity
-
Sanchez-Ramon S, et al. Pregnancy-induced expansion of regulatory T-lymphocytes may mediate protection to multiple sclerosis activity. Immunol Lett 2005;96:195-201.
-
(2005)
Immunol Lett
, vol.96
, pp. 195-201
-
-
Sanchez-Ramon, S.1
-
141
-
-
20444374502
-
CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells
-
Koenen HJ, Fasse E, Joosten I. CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells. J Immunol 2005;174:7573-7583.
-
(2005)
J Immunol
, vol.174
, pp. 7573-7583
-
-
Koenen, H.J.1
Fasse, E.2
Joosten, I.3
-
142
-
-
0036721772
-
The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
-
Szanya V, Ermann J, Taylor C, Holness C, Fathman CG. The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. J Immunol 2002;169:2461-2465.
-
(2002)
J Immunol
, vol.169
, pp. 2461-2465
-
-
Szanya, V.1
Ermann, J.2
Taylor, C.3
Holness, C.4
Fathman, C.G.5
-
143
-
-
14944346738
-
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
-
Ermann J, et al. Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood 2005;105:2220-2226.
-
(2005)
Blood
, vol.105
, pp. 2220-2226
-
-
Ermann, J.1
-
144
-
-
9444280125
-
L-Selectin (hi) but not the L-selectin (lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
-
Taylor PA, et al. L-Selectin (hi) but not the L-selectin (lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood 2004;104:3804-3812.
-
(2004)
Blood
, vol.104
, pp. 3804-3812
-
-
Taylor, P.A.1
-
145
-
-
17844364002
-
A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection
-
Suffia I, Reckling SK, Salay G, Belkaid Y. A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection. J Immunol 2005;174:5444-5455.
-
(2005)
J Immunol
, vol.174
, pp. 5444-5455
-
-
Suffia, I.1
Reckling, S.K.2
Salay, G.3
Belkaid, Y.4
-
146
-
-
27744528888
-
Homing to suppress: Address codes for Treg migration
-
Huehn J, Hamann A. Homing to suppress: address codes for Treg migration. Trends Immunol 2005;26:632-636.
-
(2005)
Trends Immunol
, vol.26
, pp. 632-636
-
-
Huehn, J.1
Hamann, A.2
-
147
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi T, et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998;10:1969-1980.
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
-
148
-
-
0141920662
-
Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells
-
Tang Q, et al. Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol 2003;171:3348-3352.
-
(2003)
J Immunol
, vol.171
, pp. 3348-3352
-
-
Tang, Q.1
-
149
-
-
0043244867
-
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo
-
Walker LS, Chodos A, Eggena M, Dooms H, Abbas AK. Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med 2003;198:249-258.
-
(2003)
J Exp Med
, vol.198
, pp. 249-258
-
-
Walker, L.S.1
Chodos, A.2
Eggena, M.3
Dooms, H.4
Abbas, A.K.5
-
150
-
-
0041884743
-
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state
-
Fisson S, et al. Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med 2003;198:737-746.
-
(2003)
J Exp Med
, vol.198
, pp. 737-746
-
-
Fisson, S.1
-
151
-
-
3142519564
-
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures
-
Godfrey WR, et al. In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures. Blood 2004;104:453-461.
-
(2004)
Blood
, vol.104
, pp. 453-461
-
-
Godfrey, W.R.1
-
152
-
-
3242801352
-
Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells
-
Hoffmann P, Eder R, Kunz-Schughart LA, Andreesen R, Edinger M. Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells. Blood 2004;104:895-903.
-
(2004)
Blood
, vol.104
, pp. 895-903
-
-
Hoffmann, P.1
Eder, R.2
Kunz-Schughart, L.A.3
Andreesen, R.4
Edinger, M.5
-
153
-
-
18144396195
-
In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation
-
Earle KE, et al. In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation. Clin Immunol 2005;115:3-9.
-
(2005)
Clin Immunol
, vol.115
, pp. 3-9
-
-
Earle, K.E.1
-
154
-
-
11244268818
-
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
-
Godfrey WR, et al. Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood 2005;105:750-758.
-
(2005)
Blood
, vol.105
, pp. 750-758
-
-
Godfrey, W.R.1
-
155
-
-
30744454570
-
Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer
-
Rapoport AP, et al. Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer. Nat Med 2005;11:1230-1237.
-
(2005)
Nat Med
, vol.11
, pp. 1230-1237
-
-
Rapoport, A.P.1
-
156
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
157
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 2004;199:1401-1408.
-
(2004)
J Exp Med
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
158
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo MG, Bacchetta R, Bordignon C, Narula S, Levings MK. Type 1 T regulatory cells. Immunol Rev 2001;182:68-79.
-
(2001)
Immunol Rev
, vol.182
, pp. 68-79
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
159
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF, Chatenoud L. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003;9:1202-1208.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
160
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold KC, et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med 2002;346:1692-1698.
-
(2002)
N Engl J Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
-
161
-
-
0038792101
-
Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells
-
Mahnke K, Qian Y, Knop J, Enk AH. Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood 2003;101:4862-4869.
-
(2003)
Blood
, vol.101
, pp. 4862-4869
-
-
Mahnke, K.1
Qian, Y.2
Knop, J.3
Enk, A.H.4
-
162
-
-
0035237036
-
Immunotherapy of type 1 diabetes mellitus
-
Chatenoud L. Immunotherapy of type 1 diabetes mellitus. Curr Dir Autoimmun 2001;4:333-350.
-
(2001)
Curr Dir Autoimmun
, vol.4
, pp. 333-350
-
-
Chatenoud, L.1
-
163
-
-
0024588763
-
Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. in vivo activation of T cells
-
Hirsch R, Gress RE, Pluznik DH, Eckhaus M, Bluestone JA. Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells. J Immunol 1989;142:737-743.
-
(1989)
J Immunol
, vol.142
, pp. 737-743
-
-
Hirsch, R.1
Gress, R.E.2
Pluznik, D.H.3
Eckhaus, M.4
Bluestone, J.A.5
-
164
-
-
0027466834
-
Devising murine models to better adapt clinical protocols: Sequential low-dose treatment with anti-CD3 and anti-CD4 monoclonal antibodies to prevent fully mismatched allograft rejection
-
Campos HH, Bach JF, Chatenoud L. Devising murine models to better adapt clinical protocols: sequential low-dose treatment with anti-CD3 and anti-CD4 monoclonal antibodies to prevent fully mismatched allograft rejection. Transplant Proc 1993;25:798-799.
-
(1993)
Transplant Proc
, vol.25
, pp. 798-799
-
-
Campos, H.H.1
Bach, J.F.2
Chatenoud, L.3
-
165
-
-
0024382830
-
In-vivo anti-CD3 treatment of autoimmune patients
-
Chatenoud L, Ferran C, Bach JF. In-vivo anti-CD3 treatment of autoimmune patients. Lancet 1989;2:164.
-
(1989)
Lancet
, vol.2
, pp. 164
-
-
Chatenoud, L.1
Ferran, C.2
Bach, J.F.3
-
166
-
-
0027083592
-
Remission of established disease in diabetic NOD mice induced by anti-CD3 monoclonal antibody
-
Chatenoud L, Thervet E, Primo J, Bach JF. Remission of established disease in diabetic NOD mice induced by anti-CD3 monoclonal antibody. C R Acad Sci III 1992;315:225-228.
-
(1992)
C R Acad Sci III
, vol.315
, pp. 225-228
-
-
Chatenoud, L.1
Thervet, E.2
Primo, J.3
Bach, J.F.4
-
167
-
-
0027958044
-
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
-
USA
-
Chatenoud L, Thervet E, Primo J, Bach JF. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci USA 1994;91:123-127.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 123-127
-
-
Chatenoud, L.1
Thervet, E.2
Primo, J.3
Bach, J.F.4
-
168
-
-
0037314237
-
Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1 (Ala-Ala)
-
Herold KC, Burton JB, Francois F, Poumian-Ruiz E, Glandt M, Bluestone JA. Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1 (Ala-Ala). J Clin Invest 2003;111:409-418.
-
(2003)
J Clin Invest
, vol.111
, pp. 409-418
-
-
Herold, K.C.1
Burton, J.B.2
Francois, F.3
Poumian-Ruiz, E.4
Glandt, M.5
Bluestone, J.A.6
-
169
-
-
0026546211
-
Prevention of autoimmune diabetes with nonactivating anti-CD3 monoclonal antibody
-
Herold KC, et al. Prevention of autoimmune diabetes with nonactivating anti-CD3 monoclonal antibody. Diabetes 1992;41:385-391.
-
(1992)
Diabetes
, vol.41
, pp. 385-391
-
-
Herold, K.C.1
-
170
-
-
0031569177
-
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
-
Chatenoud L, Primo J, Bach JF. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol 1997;158:2947-2954.
-
(1997)
J Immunol
, vol.158
, pp. 2947-2954
-
-
Chatenoud, L.1
Primo, J.2
Bach, J.F.3
-
171
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3gamma1 (Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
Herold KC, et al. A single course of anti-CD3 monoclonal antibody hOKT3gamma1 (Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 2005;54:1763-1769.
-
(2005)
Diabetes
, vol.54
, pp. 1763-1769
-
-
Herold, K.C.1
-
172
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
Keymeulen B, et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 2005;352:2598-2608.
-
(2005)
N Engl J Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
-
173
-
-
0034650845
-
Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab′)2
-
Yu XZ, Anasetti C. Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab′)2. Transplantation 2000;69:104-112.
-
(2000)
Transplantation
, vol.69
, pp. 104-112
-
-
Yu, X.Z.1
Anasetti, C.2
-
174
-
-
0033568236
-
Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1 (Ala-Ala) in the treatment of acute renal allograft rejection
-
Woodle ES, et al. Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1 (Ala-Ala) in the treatment of acute renal allograft rejection. Transplantation 1999;68:608-616.
-
(1999)
Transplantation
, vol.68
, pp. 608-616
-
-
Woodle, E.S.1
-
175
-
-
17044425656
-
Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis
-
Kohm AP, et al. Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis. J Immunol 2005;174:4525-4534.
-
(2005)
J Immunol
, vol.174
, pp. 4525-4534
-
-
Kohm, A.P.1
-
176
-
-
2142770174
-
CD3 antibody treatment stimulates the functional capability of regulatory T cells
-
Chatenoud L. CD3 antibody treatment stimulates the functional capability of regulatory T cells. Novartis Found Symp 2003;252:279-286 (discussion 286-290).
-
(2003)
Novartis Found Symp
, vol.252
, pp. 279-286
-
-
Chatenoud, L.1
-
177
-
-
23844550915
-
IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes
-
USA
-
Mekala DJ, Alli RS, Geiger TL. IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc Natl Acad Sci USA 2005;102:11817-11822.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 11817-11822
-
-
Mekala, D.J.1
Alli, R.S.2
Geiger, T.L.3
-
178
-
-
14944371830
-
Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes
-
Mekala DJ, Geiger TL. Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Blood 2005;105:2090-2092.
-
(2005)
Blood
, vol.105
, pp. 2090-2092
-
-
Mekala, D.J.1
Geiger, T.L.2
-
179
-
-
28544448646
-
Supernatural T cells: Genetic modification of T cells for cancer therapy
-
Kershaw MH, Teng MW, Smyth MJ, Darcy PK. Supernatural T cells: genetic modification of T cells for cancer therapy. Nat Rev Immunol 2005;5:928-940.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 928-940
-
-
Kershaw, M.H.1
Teng, M.W.2
Smyth, M.J.3
Darcy, P.K.4
-
180
-
-
14844352743
-
CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: Antigen-specific reactivation in vivo is critical for bystander regulation
-
Karim M, Feng G, Wood KJ, Bushell AR. CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation. Blood 2005;105:4871-4877.
-
(2005)
Blood
, vol.105
, pp. 4871-4877
-
-
Karim, M.1
Feng, G.2
Wood, K.J.3
Bushell, A.R.4
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