JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

Journal of Clinical Investigation

Volumn 106, Issue 12, 2000, Pages

  Chatila, T A ^a   Blaeser, F ^a   Ho, N ^a   Lederman, H M ^a   Voulgaropoulos, C ^a   Helms, C ^a   Bowcock, A M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; COMPLEMENTARY DNA; PROTEIN JM2; UNCLASSIFIED DRUG;

ALLERGY; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; GENE DELETION; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOPHENOTYPING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TH2 CELL; X CHROMOSOME LINKAGE;

EID: 0034526617     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI11679     Document Type: Article

References (28)

1. An X-linked syndrome of diarrhea, polyendocrinopathy, and fatal infection in infancy
2. A Japanese family of X-linked auto-immune enteropathy with haemolytic anaemia and polyendocrinopathy
3. Neonatal diabetes mellitus associated with severe diarrhea, hyperimmunoglobulin E syndrome, and absence of islets of Langerhans
4. X-linked immune dysregulation, neonatal insulin dependent diabetes, and intractable diarrhoea
5. X linked immune dysregulation, neonatal insulin dependent diabetes, and intractable diarrhoea
6. Manifestations and linkage analysis in X-linked autoimmunity-immunodeficiency syndrome
7. Congenital autoimmune diabetes mellitus
8. X-linked syndrome of polyendocrinopathy, immune dysfunction, and diarrhea maps to Xp11.23-Xq13.3
9. The absence of the transcription activator TFE3 impairs activation of B cells in vivo
10. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
11. The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome
12. Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes
13. The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the proximal X chromosome
14. A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation
15. Five years on the wings of fork head
16. Winged helix proteins
17. Human N-myc is closely related in organization and nucleotide sequence to c-myc
18. The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells
19. DNA binding by N- and L-Myc proteins
20. CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
21. Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse
22. Cellular and molecular characterization of the scurfy mouse mutant
23. Complement deficiencies
24. An inherited disorder of lymphocyte apoptosis: The autoimmune lymphoproliferative syndrome
25. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. The Finnish-German APECED Consortium. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
26. Positional cloning of the APECED gene
27. Lineage commitment in the immune system: The T helper lymphocyte grows up
28. A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients