Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression

Journal of Experimental Medicine

Volumn 193, Issue 11, 2001, Pages 1247-1260

  Finotto, Susetta ^a,b   De Sanctis, George T ^b   Lehr, Hans A ^a   Herz, Udo ^c   Buerke, Michael ^a   Schipp, Mechthild ^a   Bartsch, Brigitte ^a   Atreya, Raja ^a   Schmitt, Edgar ^a   Galle, Peter R ^a   Renz, Harald ^c   Neurath, Markus F ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Antisense DNA; Asthma; GATA 3; T cells; Th2 cytokines

Indexed keywords

ANTISENSE GATA 3; ANTISENSE OLIGONUCLEOTIDE; CELL DNA; GLUCOCORTICOID; ISOTHIOCYANIC ACID; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

AIRWAY; ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; FEMALE; INFLAMMATION; LUNG RESISTANCE; MOUSE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH2 CELL; TRANSGENIC MOUSE; TREATMENT OUTCOME;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; DNA-BINDING PROTEINS; EOSINOPHILS; FEMALE; GATA3 TRANSCRIPTION FACTOR; INTERLEUKIN-4; INTERLEUKIN-9; LUNG; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDES, ANTISENSE; OVALBUMIN; TH2 CELLS; TRANS-ACTIVATORS;

EID: 0035806279     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.11.1247     Document Type: Article

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