RNA interference: From gene silencing to gene-specific therapeutics

Pharmacology and Therapeutics

Volumn 107, Issue 2, 2005, Pages 222-239

  Leung, Ray K M ^a   Whittaker, Paul A ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Disease; RNAi; shRNA; siRNA; Therapy; Validation

Indexed keywords

SMALL INTERFERING RNA;

ASTHMA; CLINICAL TRIAL; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; GENE TARGETING; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUNTINGTON CHOREA; MOLECULAR EVOLUTION; NONHUMAN; PARKINSON DISEASE; PLASMID; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; RNA INTERFERENCE; SOLID TUMOR; SPINAL CORD INFECTION; VIRUS INFECTION;

ANIMALS; COMMUNICABLE DISEASES; DRUG DESIGN; GENE SILENCING; HUMANS; NEOPLASMS; RESPIRATORY TRACT DISEASES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 21344457432     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2005.03.004     Document Type: Review

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