Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer

Clinical Cancer Research

Volumn 10, Issue 11, 2004, Pages 3667-3677

  Zhang, Yun ^a   Zhang, Yu Feng ^a   Bryant, Joshua ^b   Charles, Andrew ^b   Boado, Ruben J ^a,c   Pardridge, William M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ArmaGen Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOLIPOSOME; LIPOSOME ENCAPSULATED PLASMID DNA; MONOCLONAL ANTIBODY; MURINE MONOCLONAL ANTIBODY 83 14; NUCLEOTIDE; PEGYLATED IMMUNOLIPOSOME; PLASMID DNA; RAT MONOCLONAL ANTIBODY 8D3; THYMIDINE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ADVANCED CANCER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CANCER; CALCIUM SIGNALING; CANCER CELL CULTURE; CANCER SURVIVAL; CONTROLLED STUDY; ENCAPSULATION; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; EPIDERMAL GROWTH FACTOR RECEPTOR RNA INTERFERENCE GENE; GENE; GENE EXPRESSION; GENE SILENCING; GLIOMA; HUMAN; HUMAN CELL; IN VIVO CULTURE; INTRAVENOUS DRUG ADMINISTRATION; INTRAVENOUS NONVIRAL GENE THERAPY; MOUSE; NONHUMAN; NONVIRAL GENE THERAPY; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; RECEPTOR AFFINITY; RNA INTERFERENCE; SCID MOUSE;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; BRAIN; BRAIN NEOPLASMS; CALCIUM; CELL LINE, TUMOR; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; GENE THERAPY; HUMANS; IMMUNOHISTOCHEMISTRY; LIGANDS; LIPOSOMES; MICE; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; OLIGONUCLEOTIDES; PLASMIDS; POLYETHYLENE GLYCOLS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; THYMIDINE; TIME FACTORS; TREATMENT OUTCOME;

EID: 2542561420     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0740     Document Type: Article

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