Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 7, 2004, Pages 1892-1897

  Scacheri, Peter C ^a   Rozenblatt Rosen, Orit ^b,c   Caplen, Natasha J ^a   Wolfsberg, Tyra G ^a   Umayam, Lowell ^a   Lee, Jeffrey C ^b   Hughes, Christina M ^b   Shanmugam, Kalai Selvi ^b   Bhattacharjee, Arindam ^c   Meyerson, Matthew ^b   Collins, Francis S ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c AGILENT TECHNOLOGIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ACTIN; BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; DOUBLE STRANDED RNA; GENE PRODUCT; INTERFERON; MEN1 PROTEIN, HUMAN; MESSENGER RNA; METHIONINE; MICRORNA; OAS1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL; ARTICLE; CELL LINE; CONTROLLED STUDY; DROSOPHILA; ENZYME SPECIFICITY; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HELA CELL; HUMAN; HUMAN CELL; MEN1 GENE; METABOLISM; MULTIPLE ENDOCRINE NEOPLASIA; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY; TRANSLATION REGULATION; WESTERN BLOTTING;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; BLOTTING, WESTERN; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INTERFERONS; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY; SUBSTRATE SPECIFICITY; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MAMMALIA;

EID: 10744219688     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0308698100     Document Type: Article

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