-
1
-
-
0033555703
-
RNAi and double-strand RNA
-
Sharp PA. 1999. RNAi and double-strand RNA. Genes Dev. 13:139-41
-
(1999)
Genes Dev.
, vol.13
, pp. 139-141
-
-
Sharp, P.A.1
-
2
-
-
0033119713
-
Fast forward genetics based on virus-induced gene silencing
-
Baulcombe DC. 1999. Fast forward genetics based on virus-induced gene silencing. Curr. Opin. Plant Biol. 2:109-13
-
(1999)
Curr. Opin. Plant Biol.
, vol.2
, pp. 109-113
-
-
Baulcombe, D.C.1
-
3
-
-
0034636715
-
dsRNA-mediated gene silencing in cultured Drosophila cells: A tissue culture model for the analysis of RNA interference
-
Caplen NJ, Fleenor J, Fire A, Morgan RA. 2000. dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference. Gene. 252:95-105
-
(2000)
Gene
, vol.252
, pp. 95-105
-
-
Caplen, N.J.1
Fleenor, J.2
Fire, A.3
Morgan, R.A.4
-
4
-
-
0034683099
-
Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
-
Ui-Tei K, Zenno S, Miyata Y, Saigo K. 2000. Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS. Lett. 479:79-82
-
(2000)
FEBS. Lett.
, vol.479
, pp. 79-82
-
-
Ui-Tei, K.1
Zenno, S.2
Miyata, Y.3
Saigo, K.4
-
5
-
-
0031657551
-
How cells respond to interferons
-
Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. 1998. How cells respond to interferons. Annu. Rev. Biochem. 67:227-64
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
6
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-98
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
7
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-11
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
9
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-54
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
11
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
Lau NC, Lim LP, Weinstein EG, Bartel DP. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294:858-62
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
12
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
Lee RC, Ambros V. 2001. An extensive class of small RNAs in Caenorhabditis elegans. Science 294:862-64
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
13
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP. 2003. Vertebrate microRNA genes. Science 299:1540
-
(2003)
Science
, vol.299
, pp. 1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
14
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen CZ, Li L, Lodish HF, Bartel DP. 2004. MicroRNAs modulate hematopoietic lineage differentiation. Science 303:83-86
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
15
-
-
18744396337
-
Frequent deletions and down-regulation of microRNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, et al. 2002. Frequent deletions and down-regulation of microRNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 99:15524-29
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
-
16
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, et al. 2004. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. USA 101:2999-3004
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
-
17
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-97
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
18
-
-
0037197803
-
Identification of tissue-specific micro RNAs from mouse
-
Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. 2002. Identification of tissue-specific micro RNAs from mouse. Curr. Biol. 12:735-39
-
(2002)
Curr. Biol.
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
19
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee Y, Jeon K, Lee JT, Kim S, Kim VN. 2002. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21:4663-70
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
20
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, et al. 2003. The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415-19
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
-
21
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-66
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
22
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner G, Zamore PD. 2002. A microRNA in a multiple-turnover RNAi enzyme complex. Science 297:2056-60
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
23
-
-
0037076320
-
ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
-
Williams RW, Rubin GM. 2002. ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc. Natl. Acad. Sci. USA 99:6889-94
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6889-6894
-
-
Williams, R.W.1
Rubin, G.M.2
-
24
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ. 2001. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293:1146-50
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
25
-
-
0042124978
-
Identification of eight members of the Argonaute family in the human genome small star, filled
-
Sasaki T, Shiohama A, Minoshima S, Shimizu N. 2003. Identification of eight members of the Argonaute family in the human genome small star, filled. Genomics 82:323-30
-
(2003)
Genomics
, vol.82
, pp. 323-330
-
-
Sasaki, T.1
Shiohama, A.2
Minoshima, S.3
Shimizu, N.4
-
26
-
-
0032717319
-
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
-
Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, et al. 1999. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99:123-32
-
(1999)
Cell
, vol.99
, pp. 123-132
-
-
Tabara, H.1
Sarkissian, M.2
Kelly, W.G.3
Fleenor, J.4
Grishok, A.5
-
27
-
-
0036009918
-
Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance
-
Morel JB, Godon C, Mourrain P, Beclin C, Boulet S, et al. 2002. Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance. Plant Cell 14:629-39
-
(2002)
Plant Cell
, vol.14
, pp. 629-639
-
-
Morel, J.B.1
Godon, C.2
Mourrain, P.3
Beclin, C.4
Boulet, S.5
-
28
-
-
0037087780
-
miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, et al. 2002. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16:720-28
-
(2002)
Genes Dev.
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
Dostie, J.2
Paushkin, S.3
Sharma, A.4
Charroux, B.5
-
29
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T. 2002. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110:563-74
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
30
-
-
0242266620
-
Dicer is essential for mouse development
-
Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, et al. 2003. Dicer is essential for mouse development. Nat. Genet. 35:215-17
-
(2003)
Nat. Genet.
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
Murchison, E.P.4
Alcorn, H.5
-
31
-
-
0242266618
-
The microRNA-producing enzyme Dicer1 is essential for zebrafish development
-
Wienholds E, Koudijs MJ, van Eeden FJ, Cuppen E, Plasterk RH. 2003. The microRNA-producing enzyme Dicer1 is essential for zebrafish development. Nat. Genet. 35:217-18
-
(2003)
Nat. Genet.
, vol.35
, pp. 217-218
-
-
Wienholds, E.1
Koudijs, M.J.2
Van Eeden, F.J.3
Cuppen, E.4
Plasterk, R.H.5
-
32
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, et al. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
-
33
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD. 2001. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293:834-38
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
34
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15:2654-59
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
35
-
-
1942435249
-
Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
-
Bartel DP, Chen CZ. 2004. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5:396-400
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 396-400
-
-
Bartel, D.P.1
Chen, C.Z.2
-
38
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-53
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
39
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G, Soohoo C, Affar el B, Gay F, Shi Y, Forrester WC. 2002. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99:5515-20
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affar El, B.3
Gay, F.4
Shi, Y.5
Forrester, W.C.6
-
41
-
-
0037948173
-
Generation of Ski-knockdown mice by expressing along double-strand RNA from an RNA polymerase II promoter
-
Shinagawa T, Ishii S. 2003. Generation of Ski-knockdown mice by expressing along double-strand RNA from an RNA polymerase II promoter. Genes Dev. 17:1340-45
-
(2003)
Genes Dev.
, vol.17
, pp. 1340-1345
-
-
Shinagawa, T.1
Ishii, S.2
-
42
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. 1999. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13:3191-97
-
(1999)
Genes Dev.
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
43
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
44
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A, Reynolds A, Jayasena SD. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-16
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
45
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, Khvorova A. 2004. Rational siRNA design for RNA interference. Nat. Biotechnol. 22:326-30
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
46
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen T, Fleenor J, Simmer F, Thijssen KL, Parrish S, et al. 2001. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107:465-76
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
Thijssen, K.L.4
Parrish, S.5
-
47
-
-
0034708215
-
EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans
-
Smardon A, Spoerke JM, Stacey SC, Klein ME, Mackin N, Maine EM. 2000. EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans. Curr. Biol 10:169-78
-
(2000)
Curr. Biol.
, vol.10
, pp. 169-178
-
-
Smardon, A.1
Spoerke, J.M.2
Stacey, S.C.3
Klein, M.E.4
Mackin, N.5
Maine, E.M.6
-
48
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E, Lee SK, Wang J, Ince N, Ouyang N, et al. 2003. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9:347-51
-
(2003)
Nat. Med.
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
Ince, N.4
Ouyang, N.5
-
49
-
-
0037663944
-
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages
-
Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, et al. 2003. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J. Virol. 77:7174-81
-
(2003)
J. Virol.
, vol.77
, pp. 7174-7181
-
-
Song, E.1
Lee, S.K.2
Dykxhoorn, D.M.3
Novina, C.4
Zhang, D.5
-
50
-
-
0034652838
-
Survey and summary: Transcription by RNA polymerases I and III
-
Paule MR, White RJ. 2000. Survey and summary: transcription by RNA polymerases I and III. Nucleic Acids Res. 28:1283-98
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1283-1298
-
-
Paule, M.R.1
White, R.J.2
-
51
-
-
0345374597
-
Promoter choice affects the potency of HIV-1 specific RNA interference
-
Boden D, Pusch O, Lee F, Tucker L, Shank PR, Ramratnam B. 2003. Promoter choice affects the potency of HIV-1 specific RNA interference. Nucleic Acids Res. 31:5033-38
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 5033-5038
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Shank, P.R.5
Ramratnam, B.6
-
52
-
-
0037440160
-
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
-
Kawasaki H, Taira K. 2003. Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res. 31:700-7
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 700-707
-
-
Kawasaki, H.1
Taira, K.2
-
53
-
-
0344211452
-
Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer
-
Zhang L, Yang N, Mohamed-Hadley A, Rubin SC, Coukos G. 2003. Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer. Biochem Biophys. Res. Commun. 303:1169-78
-
(2003)
Biochem Biophys. Res. Commun.
, vol.303
, pp. 1169-1178
-
-
Zhang, L.1
Yang, N.2
Mohamed-Hadley, A.3
Rubin, S.C.4
Coukos, G.5
-
54
-
-
1542604807
-
An enhanced U6 promoter for synthesis of short hairpin RNA
-
Xia XG, Zhou H, Ding H, Affar el B, Shi Y, Xu Z. 2003. An enhanced U6 promoter for synthesis of short hairpin RNA. Nucleic Acids Res. 31:e100
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Xia, X.G.1
Zhou, H.2
Ding, H.3
Affar El, B.4
Shi, Y.5
Xu, Z.6
-
56
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng Y, Wagner EJ, Cullen BR. 2002. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell. 9:1327-33
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
57
-
-
0037111232
-
Small interfering RNA-mediated gene silencing in T lymphocytes
-
McManus MT, Haines BB, Dillon CP, Whitehurst CE, van Parijs L, et al. 2002. Small interfering RNA-mediated gene silencing in T lymphocytes. J. Immunol. 169:5754-60
-
(2002)
J. Immunol.
, vol.169
, pp. 5754-5760
-
-
McManus, M.T.1
Haines, B.B.2
Dillon, C.P.3
Whitehurst, C.E.4
Van Parijs, L.5
-
58
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. 2002. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2:243-47
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
59
-
-
0344668868
-
Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA
-
Pusch O, Boden D, Silbermann R, Lee F, Tucker L, Ramratnam B. 2003. Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA. Nucleic Acids Res. 31:6444-49
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6444-6449
-
-
Pusch, O.1
Boden, D.2
Silbermann, R.3
Lee, F.4
Tucker, L.5
Ramratnam, B.6
-
60
-
-
0347623204
-
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
-
Persengiev SP, Zhu X, Green MR. 2004. Nonspecific, concentration- dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA 10:12-18
-
(2004)
RNA
, vol.10
, pp. 12-18
-
-
Persengiev, S.P.1
Zhu, X.2
Green, M.R.3
-
61
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, et al. 2003. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21:635-37
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
-
62
-
-
0142173075
-
Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
-
Saxena S, Jonsson ZO, Dutta A. 2003. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem. 278:44312-19
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44312-44319
-
-
Saxena, S.1
Jonsson, Z.O.2
Dutta, A.3
-
63
-
-
1942499451
-
Improving the efficiency of RNA interference in mammals
-
a. Mittal V. 2004. Improving the efficiency of RNA interference in mammals. Nat. Rev. Genet. 5:355-65
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 355-365
-
-
Mittal, V.1
-
64
-
-
0034877670
-
RNA interference: Listening to the sound of silence
-
Zamore PD. 2001. RNA interference: listening to the sound of silence. Nat. Struct. Biol. 8:746-50
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 746-750
-
-
Zamore, P.D.1
-
65
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R. 2003. Induction of an interferon response by RNAi vectors in mammalian cells. Nat. Genet. 34:263-64
-
(2003)
Nat. Genet.
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
66
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
-
Kim DH, Longo M, Han Y, Lundberg P, Cantin E, Rossi JJ. 2004. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat. Biotechnol. 22:321-25
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
Lundberg, P.4
Cantin, E.5
Rossi, J.J.6
-
67
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA, Holko M, de Veer MJ, Silverman RH, Williams BR. 2003. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 5:834-39
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
De Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
68
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413:732-38
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
69
-
-
2442705429
-
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3
-
Kariko K, Bhuyan P, Capodici J, Weissman D. 2004. Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3. J. Immunol. 172:6545-49
-
(2004)
J. Immunol.
, vol.172
, pp. 6545-6549
-
-
Kariko, K.1
Bhuyan, P.2
Capodici, J.3
Weissman, D.4
-
70
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. 2002. RNA interference in adult mice. Nature 418:38-39
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.J.5
Kay, M.A.6
-
71
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32:107-8
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
72
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen DR, Leirdal M, Sioud M. 2003. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327:761-66
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
73
-
-
0347363469
-
BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia
-
Baker-Herman TL, Fuller DD, Bavis RW, Zabka AG, Golder FJ, et al. 2004. BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia. Nat. Neurosci. 7:48-55
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 48-55
-
-
Baker-Herman, T.L.1
Fuller, D.D.2
Bavis, R.W.3
Zabka, A.G.4
Golder, F.J.5
-
74
-
-
1942494048
-
Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA
-
Kishida T, Asada H, Gojo S, Ohashi S, Shin-Ya M, et al. 2004. Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA. J. Gene Med. 6:105-10
-
(2004)
J. Gene Med.
, vol.6
, pp. 105-110
-
-
Kishida, T.1
Asada, H.2
Gojo, S.3
Ohashi, S.4
Shin-Ya, M.5
-
75
-
-
1142274208
-
Cdh1-APC controls axonal growth and patterning in the mammalian brain
-
Konishi Y, Stegmuller J, Matsuda T, Bonni S, Bonni A. 2004. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 303:1026-30
-
(2004)
Science
, vol.303
, pp. 1026-1030
-
-
Konishi, Y.1
Stegmuller, J.2
Matsuda, T.3
Bonni, S.4
Bonni, A.5
-
76
-
-
1642487117
-
Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference
-
Kong XC, Barzaghi P, Ruegg MA. 2004. Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference. EMBO Rep. 5:183-88
-
(2004)
EMBO Rep.
, vol.5
, pp. 183-188
-
-
Kong, X.C.1
Barzaghi, P.2
Ruegg, M.A.3
-
77
-
-
0347089037
-
Electroporation and RNA interference in the rodent retina in vivo and in vitro
-
Matsuda T, Cepko CL. 2004. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. USA 101:16-22
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16-22
-
-
Matsuda, T.1
Cepko, C.L.2
-
78
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
Braasch DA, Jensen S, Liu Y, Kaur K, Arar K, et al. 2003. RNA interference in mammalian cells by chemically-modified RNA. Biochemistry 42:7967-75
-
(2003)
Biochemistry
, vol.42
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
Kaur, K.4
Arar, K.5
-
79
-
-
1242316928
-
Biodistribution of phosphodiester and phosphorothioate siRNA
-
Braasch DA, Paroo Z, Constantinescu A, Ren G, Oz OK, et al. 2004. Biodistribution of phosphodiester and phosphorothioate siRNA. Bioorg. Med. Chem. Lett. 14:1139-43
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 1139-1143
-
-
Braasch, D.A.1
Paroo, Z.2
Constantinescu, A.3
Ren, G.4
Oz, O.K.5
-
80
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
Czauderna F, Fechtner M, Dames S, Aygun H, Klippel A, et al. 2003. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 31:2705-16
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygun, H.4
Klippel, A.5
-
81
-
-
0041331496
-
siRNA function in RNAi: A chemical modification analysis
-
Chiu YL, Rana TM. 2003. siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-48
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
82
-
-
1942523210
-
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats
-
Zhang Y, Boado RJ, Pardridge WM. 2003. In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. J. Gene Med. 5:1039-45
-
(2003)
J. Gene Med.
, vol.5
, pp. 1039-1045
-
-
Zhang, Y.1
Boado, R.J.2
Pardridge, W.M.3
-
83
-
-
0842346326
-
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
-
Muratovska A, Eccles MR. 2004. Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett. 558:63-68
-
(2004)
FEBS Lett.
, vol.558
, pp. 63-68
-
-
Muratovska, A.1
Eccles, M.R.2
-
85
-
-
0036976008
-
Lentiviral-mediated RNA interference
-
Abbas-Terki T, Blanco-Bose W, Deglon N, Pralong W, Aebischer P. 2002. Lentiviral-mediated RNA interference. Hum. Gene Ther. 13:2197-201
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 2197-2201
-
-
Abbas-Terki, T.1
Blanco-Bose, W.2
Deglon, N.3
Pralong, W.4
Aebischer, P.5
-
86
-
-
0037686707
-
Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53
-
Dirac AM, Bernards R. 2003. Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. J. Biol. Chem. 278:11731-34
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11731-11734
-
-
Dirac, A.M.1
Bernards, R.2
-
87
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann MT, Fridman JS, Zilfou JT, Hernando E, Paddison PJ, et al. 2003. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat. Genet. 33:396-400
-
(2003)
Nat. Genet.
, vol.33
, pp. 396-400
-
-
Hemann, M.T.1
Fridman, J.S.2
Zilfou, J.T.3
Hernando, E.4
Paddison, P.J.5
-
88
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, et al. 2003. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33:401-6
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
-
89
-
-
0344375083
-
Lentivirus-delivered stable gene silencing by RNAi in primary cells
-
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, et al. 2003. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9:493-501
-
(2003)
RNA
, vol.9
, pp. 493-501
-
-
Stewart, S.A.1
Dykxhoorn, D.M.2
Palliser, D.3
Mizuno, H.4
Yu, E.Y.5
-
90
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia G, Singer O, Ikawa M, Verma IM. 2003. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100:1844-48
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
91
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin XF, An DS, Chen IS, Baltimore D. 2003. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA 100:183-88
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.3
Baltimore, D.4
-
92
-
-
0346216853
-
Local gene knockdown in the brain using viral-mediated RNA interference
-
Hommel JD, Sears RM, Georgescu D, Simmons DL, DiLeone RJ. 2003. Local gene knockdown in the brain using viral-mediated RNA interference. Nat. Med. 9:1539-44
-
(2003)
Nat. Med.
, vol.9
, pp. 1539-1544
-
-
Hommel, J.D.1
Sears, R.M.2
Georgescu, D.3
Simmons, D.L.4
DiLeone, R.J.5
-
93
-
-
10744221455
-
Adenoviral vectors expressing siRNAs for discovery and validation of gene function
-
Arts GJ, Langemeijer E, Tissingh R, Ma L, Pavliska H, et al. 2003. Adenoviral vectors expressing siRNAs for discovery and validation of gene function. Genome Res. 13:2325-32
-
(2003)
Genome Res.
, vol.13
, pp. 2325-2332
-
-
Arts, G.J.1
Langemeijer, E.2
Tissingh, R.3
Ma, L.4
Pavliska, H.5
-
94
-
-
0037468660
-
Gene silencing by adenovirus-delivered siRNA
-
Shen C, Buck AK, Liu X, Winkler M, Reske SN. 2003. Gene silencing by adenovirus-delivered siRNA. FEBS Lett. 539:111-14
-
(2003)
FEBS Lett.
, vol.539
, pp. 111-114
-
-
Shen, C.1
Buck, A.K.2
Liu, X.3
Winkler, M.4
Reske, S.N.5
-
95
-
-
0141991324
-
Specific gene inhibition by adenovirus-mediated expression of small interfering RNA
-
Zhao LJ, Jian H, Zhu H. 2003. Specific gene inhibition by adenovirus-mediated expression of small interfering RNA. Gene 316:137-41
-
(2003)
Gene
, vol.316
, pp. 137-141
-
-
Zhao, L.J.1
Jian, H.2
Zhu, H.3
-
96
-
-
1942537043
-
Advances in AAV-mediated gene transfer for the treatment of inherited disorders
-
Hildinger M, Auricchio A. 2004. Advances in AAV-mediated gene transfer for the treatment of inherited disorders. Eur. J. Hum. Genet. 12:263-71
-
(2004)
Eur. J. Hum. Genet.
, vol.12
, pp. 263-271
-
-
Hildinger, M.1
Auricchio, A.2
-
97
-
-
0041806502
-
Looking into the safety of AAV vectors
-
Kay MA, Nakai H. 2003. Looking into the safety of AAV vectors. Nature 424:251
-
(2003)
Nature
, vol.424
, pp. 251
-
-
Kay, M.A.1
Nakai, H.2
-
98
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
Thomas CE, Ehrhardt A, Kay MA. 2003. Progress and problems with the use of viral vectors for gene therapy. Nat. Rev. Genet. 4:346-58
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
99
-
-
1642443401
-
Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors
-
Boden D, Pusch O, Lee F, Tucker L, Ramratnam B. 2004. Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors. Mol. Ther. 9:396-402
-
(2004)
Mol. Ther.
, vol.9
, pp. 396-402
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Ramratnam, B.5
-
100
-
-
4043057946
-
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
-
Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, et al. 2004. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat. Med. 10:816-20
-
(2004)
Nat. Med.
, vol.10
, pp. 816-820
-
-
Xia, H.1
Mao, Q.2
Eliason, S.L.3
Harper, S.Q.4
Martins, I.H.5
-
101
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. 2002. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532:227-30
-
(2002)
FEBS Lett.
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
102
-
-
0037377201
-
Transgenic RNAi in mouse oocytes: A simple and fast approach to study gene function
-
Stein P, Svoboda P, Schultz RM. 2003. Transgenic RNAi in mouse oocytes: a simple and fast approach to study gene function. Dev. Biol. 256:187-93
-
(2003)
Dev. Biol.
, vol.256
, pp. 187-193
-
-
Stein, P.1
Svoboda, P.2
Schultz, R.M.3
-
103
-
-
0347986844
-
Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting
-
Fedoriw AM, Stein P, Svoboda P, Schultz RM, Bartolomei MS. 2004. Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science 303:238-40
-
(2004)
Science
, vol.303
, pp. 238-240
-
-
Fedoriw, A.M.1
Stein, P.2
Svoboda, P.3
Schultz, R.M.4
Bartolomei, M.S.5
-
104
-
-
0037312978
-
Germline transmission of RNAi in mice
-
Carmell MA, Zhang L, Conklin DS, Hannon GJ, Rosenquist TA. 2003. Germline transmission of RNAi in mice. Nat. Struct. Biol. 10:91-92
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 91-92
-
-
Carmell, M.A.1
Zhang, L.2
Conklin, D.S.3
Hannon, G.J.4
Rosenquist, T.A.5
-
105
-
-
0038708339
-
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
-
Kunath T, Gish G, Lickert H, Jones N, Pawson T, Rossant J. 2003. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 21:559-61
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 559-561
-
-
Kunath, T.1
Gish, G.2
Lickert, H.3
Jones, N.4
Pawson, T.5
Rossant, J.6
-
106
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
Gonczy P, Echeverri C, Oegema K, Coulson A, Jones SJ, et al. 2000. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408:331-36
-
(2000)
Nature
, vol.408
, pp. 331-336
-
-
Gonczy, P.1
Echeverri, C.2
Oegema, K.3
Coulson, A.4
Jones, S.J.5
-
107
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
Fraser AG, Kamath RS, Zipperlen P, Martinez-Campos M, Sohrmann M, Ahringer J. 2000. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408:325-30
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
Kamath, R.S.2
Zipperlen, P.3
Martinez-Campos, M.4
Sohrmann, M.5
Ahringer, J.6
-
108
-
-
0035941485
-
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
Timmons L, Court DL, Fire A. 2001. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263:103-12
-
(2001)
Gene
, vol.263
, pp. 103-112
-
-
Timmons, L.1
Court, D.L.2
Fire, A.3
-
109
-
-
0032578911
-
Specific interference by ingested dsRNA
-
Timmons L, Fire A. 1998. Specific interference by ingested dsRNA. Nature 395:854
-
(1998)
Nature
, vol.395
, pp. 854
-
-
Timmons, L.1
Fire, A.2
-
110
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. 2003. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421:231-37
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
-
111
-
-
1542298437
-
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions
-
Simmer F, Moorman C, Van Der Linden AM, Kuijk E, Van Den Berghe PV, et al. 2003. Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol. 1:E12
-
(2003)
PLoS Biol.
, vol.1
-
-
Simmer, F.1
Moorman, C.2
Van Der Linden, A.M.3
Kuijk, E.4
Van Den Berghe, P.V.5
-
112
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. 2003. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat. Genet. 33:40-48
-
(2003)
Nat. Genet.
, vol.33
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
113
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, et al. 2003. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421:268-72
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
Fraser, A.G.4
Kamath, R.S.5
-
114
-
-
0037443054
-
Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
-
Pothof J, van Haaften G, Thijssen K, Kamath RS, Fraser AG, et al. 2003. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev. 17:443-48
-
(2003)
Genes Dev.
, vol.17
, pp. 443-448
-
-
Pothof, J.1
Van Haaften, G.2
Thijssen, K.3
Kamath, R.S.4
Fraser, A.G.5
-
115
-
-
0034649570
-
RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans
-
Piano F, Schetter AJ, Mangone M, Stein L, Kemphues KJ. 2000. RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans. Curr. Biol. 10:1619-22
-
(2000)
Curr. Biol.
, vol.10
, pp. 1619-1622
-
-
Piano, F.1
Schetter, A.J.2
Mangone, M.3
Stein, L.4
Kemphues, K.J.5
-
116
-
-
1342346710
-
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
-
Kennedy S, Wang D, Ruvkun G. 2004. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 427:645-49
-
(2004)
Nature
, vol.427
, pp. 645-649
-
-
Kennedy, S.1
Wang, D.2
Ruvkun, G.3
-
117
-
-
0037103781
-
Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases
-
Muda M, Worby CA, Simonson-Leff N, Clemens JC, Dixon JE. 2002. Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem. J. 366:73-77
-
(2002)
Biochem. J.
, vol.366
, pp. 73-77
-
-
Muda, M.1
Worby, C.A.2
Simonson-Leff, N.3
Clemens, J.C.4
Dixon, J.E.5
-
118
-
-
0034612276
-
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
-
Clemens JC, Worby CA, Simonson-Leff N, Muda M, Maehama T, et al. 2000. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97:6499-503
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6499-6503
-
-
Clemens, J.C.1
Worby, C.A.2
Simonson-Leff, N.3
Muda, M.4
Maehama, T.5
-
119
-
-
0037470952
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, et al. 2003. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299:2039-45
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
Yao, S.2
Mozer, B.3
Rovescalli, A.4
Von Kessler, D.5
-
120
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger A, Baum B, Jones S, Jones M, Coulson A, et al. 2003. A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2:27
-
(2003)
J. Biol.
, vol.2
, pp. 27
-
-
Kiger, A.1
Baum, B.2
Jones, S.3
Jones, M.4
Coulson, A.5
-
121
-
-
0347719384
-
A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos
-
Kim YO, Park SJ, Balaban RS, Nirenberg M, Kim Y. 2004. A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos. Proc. Natl. Acad. Sci. USA 101:159-64
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 159-164
-
-
Kim, Y.O.1
Park, S.J.2
Balaban, R.S.3
Nirenberg, M.4
Kim, Y.5
-
122
-
-
0036329002
-
Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells
-
Somma MP, Fasulo B, Cenci G, Cundari E, Gatti M. 2002. Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells. Mol. Biol. Cell. 13:2448-60
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2448-2460
-
-
Somma, M.P.1
Fasulo, B.2
Cenci, G.3
Cundari, E.4
Gatti, M.5
-
123
-
-
0037061482
-
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
-
Ramet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezekowitz RA. 2002. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416:644-48
-
(2002)
Nature
, vol.416
, pp. 644-648
-
-
Ramet, M.1
Manfruelli, P.2
Pearson, A.3
Mathey-Prevot, B.4
Ezekowitz, R.A.5
-
124
-
-
19344370696
-
Functional dissection of an innate immune response by a genome-wide RNAi screen
-
Foley E, O'Farrell PH. 2004. Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2:E203
-
(2004)
PLoS Biol.
, vol.2
-
-
Foley, E.1
O'Farrell, P.H.2
-
125
-
-
0842309871
-
Genome-wide RNAi analysis of growth and viability in Drosophila cells
-
Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, et al. 2004. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303:832-35
-
(2004)
Science
, vol.303
, pp. 832-835
-
-
Boutros, M.1
Kiger, A.A.2
Armknecht, S.3
Kerr, K.4
Hild, M.5
-
126
-
-
0141750434
-
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
-
Aza-Blanc P, Cooper CL, Wagner K, Batalov S, Deveraux QL, Cooke MP. 2003. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol. Cell. 12:627-37
-
(2003)
Mol. Cell
, vol.12
, pp. 627-637
-
-
Aza-Blanc, P.1
Cooper, C.L.2
Wagner, K.3
Batalov, S.4
Deveraux, Q.L.5
Cooke, M.P.6
-
127
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
-
Brummelkamp TR, Nijman SM, Dirac AM, Bernards R. 2003. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 424:797-801
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.2
Dirac, A.M.3
Bernards, R.4
-
128
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, et al. 2004. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428:431-37
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
Hijmans, E.M.2
Mullenders, J.3
Brummelkamp, T.R.4
Velds, A.5
-
129
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, et al. 2004. A resource for large-scale RNA-interference-based screens in mammals. Nature 428:427-31
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
Silva, J.M.2
Conklin, D.S.3
Schlabach, M.4
Li, M.5
-
130
-
-
0347089019
-
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
-
Zheng L, Liu J, Batalov S, Zhou D, Orth A, et al. 2004. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 101:135-40
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 135-140
-
-
Zheng, L.1
Liu, J.2
Batalov, S.3
Zhou, D.4
Orth, A.5
-
131
-
-
0142092529
-
High-throughput selection of effective RNAi probes for gene silencing
-
Kumar R, Conklin DS, Mittal V. 2003. High-throughput selection of effective RNAi probes for gene silencing. Genome Res. 13:2333-40
-
(2003)
Genome Res.
, vol.13
, pp. 2333-2340
-
-
Kumar, R.1
Conklin, D.S.2
Mittal, V.3
-
132
-
-
10744230287
-
RNAi microarray analysis in cultured mammalian cells
-
Mousses S, Caplen NJ, Cornelison R, Weaver D, Basik M, et al. 2003. RNAi microarray analysis in cultured mammalian cells. Genome Res. 13:2341-47
-
(2003)
Genome Res.
, vol.13
, pp. 2341-2347
-
-
Mousses, S.1
Caplen, N.J.2
Cornelison, R.3
Weaver, D.4
Basik, M.5
-
133
-
-
0141569812
-
Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
-
Lieberman J, Song E, Lee SK, Shankar P. 2003. Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends Mol. Med. 9:397-403
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 397-403
-
-
Lieberman, J.1
Song, E.2
Lee, S.K.3
Shankar, P.4
-
134
-
-
0242317385
-
Small RNA: Can RNA interference be exploited for therapy?
-
Wall NR, Shi Y. 2003. Small RNA: can RNA interference be exploited for therapy? Lancet 362:1401-3
-
(2003)
Lancet
, vol.362
, pp. 1401-1403
-
-
Wall, N.R.1
Shi, Y.2
-
135
-
-
0037168029
-
RNA interference - A new weapon against HIV and beyond
-
Kitabwalla M, Ruprecht RM. 2002. RNA interference - a new weapon against HIV and beyond. N. Engl. J. Med. 347:1364-67
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 1364-1367
-
-
Kitabwalla, M.1
Ruprecht, R.M.2
-
136
-
-
0242379146
-
Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
-
Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, et al. 2003. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell 2:209-17
-
(2003)
Aging Cell
, vol.2
, pp. 209-217
-
-
Ding, H.1
Schwarz, D.S.2
Keene, A.3
Affar El, B.4
Fenton, L.5
-
137
-
-
0141790842
-
Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571)
-
Wohlbold L, van der Kuip H, Miething C, Vomlocher HP, Knabbe C, et al. 2003. Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571). Blood 102:2236-39
-
(2003)
Blood
, vol.102
, pp. 2236-2239
-
-
Wohlbold, L.1
Van Der Kuip, H.2
Miething, C.3
Vomlocher, H.P.4
Knabbe, C.5
-
138
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda M, Fuchs U, Wossmann W, Borkhardt A. 2002. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene 21:5716-24
-
(2002)
Oncogene
, vol.21
, pp. 5716-5724
-
-
Wilda, M.1
Fuchs, U.2
Wossmann, W.3
Borkhardt, A.4
-
139
-
-
0141706705
-
siRNA agents inhibit oncogene expression and attenuate human tumor cell growth
-
Yin JQ, Gao J, Shao R, Tian WN, Wang J, Wan Y. 2003. siRNA agents inhibit oncogene expression and attenuate human tumor cell growth. J. Exp. Ther. Oncol. 3:194-204
-
(2003)
J. Exp. Ther. Oncol.
, vol.3
, pp. 194-204
-
-
Yin, J.Q.1
Gao, J.2
Shao, R.3
Tian, W.N.4
Wang, J.5
Wan, Y.6
-
140
-
-
0042173218
-
SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
-
Filleur S, Courtin A, Ait-Si-Ali S, Guglielmi J, Merle C, et al. 2003. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 63:3919-22
-
(2003)
Cancer Res.
, vol.63
, pp. 3919-3922
-
-
Filleur, S.1
Courtin, A.2
Ait-Si-Ali, S.3
Guglielmi, J.4
Merle, C.5
-
141
-
-
0242493171
-
RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
-
Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. 2003. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem. Biophys. Res. Commun. 311:786-92
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 786-792
-
-
Duxbury, M.S.1
Ito, H.2
Benoit, E.3
Zinner, M.J.4
Ashley, S.W.5
Whang, E.E.6
-
142
-
-
2342538514
-
Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells
-
Lima RT, Martins LM, Guimaraes JE, Sambade C, Vasconcelos MH. 2004. Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. Cancer Gene Ther. 11:309-16
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 309-316
-
-
Lima, R.T.1
Martins, L.M.2
Guimaraes, J.E.3
Sambade, C.4
Vasconcelos, M.H.5
-
143
-
-
0037526598
-
Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)
-
Nieth C, Priebsch A, Stege A, Lage H. 2003. Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett. 545:144-50
-
(2003)
FEBS Lett.
, vol.545
, pp. 144-150
-
-
Nieth, C.1
Priebsch, A.2
Stege, A.3
Lage, H.4
-
144
-
-
0141730323
-
siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells
-
Butz K, Ristriani T, Hengstermann A, Denk C, Scheffner M, Hoppe-Seyler F. 2003. siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells. Oncogene 22:5938-45
-
(2003)
Oncogene
, vol.22
, pp. 5938-5945
-
-
Butz, K.1
Ristriani, T.2
Hengstermann, A.3
Denk, C.4
Scheffner, M.5
Hoppe-Seyler, F.6
-
145
-
-
0038032792
-
RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells
-
Hall AH, Alexander KA. 2003. RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells. J. Virol. 77:6066-69
-
(2003)
J. Virol.
, vol.77
, pp. 6066-6069
-
-
Hall, A.H.1
Alexander, K.A.2
-
146
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, et al. 2003. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc. Natl. Acad. Sci. USA 100:2718-23
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2718-2723
-
-
Ge, Q.1
McManus, M.T.2
Nguyen, T.3
Shen, C.H.4
Sharp, P.A.5
-
147
-
-
0346873025
-
Small interfering RNA inhibits hepatitis B virus replication in mice
-
Giladi H, Ketzinel-Gilad M, Rivkin L, Felig Y, Nussbaum O, Galun E. 2003. Small interfering RNA inhibits hepatitis B virus replication in mice. Mol. Ther. 8:769-76
-
(2003)
Mol. Ther.
, vol.8
, pp. 769-776
-
-
Giladi, H.1
Ketzinel-Gilad, M.2
Rivkin, L.3
Felig, Y.4
Nussbaum, O.5
Galun, E.6
-
148
-
-
10744230911
-
Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
-
Yokota T, Sakamoto N, Enomoto N, Tanabe Y, Miyagishi M, et al. 2003. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO Rep. 4:602-8
-
(2003)
EMBO Rep.
, vol.4
, pp. 602-608
-
-
Yokota, T.1
Sakamoto, N.2
Enomoto, N.3
Tanabe, Y.4
Miyagishi, M.5
-
149
-
-
12144289381
-
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
-
Kronke J, Kittler R, Buchholz F, Windisch MP, Pietschmann T, et al. 2004. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J. Virol. 78:3436-46
-
(2004)
J. Virol.
, vol.78
, pp. 3436-3446
-
-
Kronke, J.1
Kittler, R.2
Buchholz, F.3
Windisch, M.P.4
Pietschmann, T.5
-
150
-
-
10744221444
-
Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference
-
Zhang Y, Li T, Fu L, Yu C, Li Y, et al. 2004. Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference. FEBS Lett. 560:141-46
-
(2004)
FEBS Lett.
, vol.560
, pp. 141-146
-
-
Zhang, Y.1
Li, T.2
Fu, L.3
Yu, C.4
Li, Y.5
-
151
-
-
2942530436
-
Inhibition of influenza virus production in virus-infected mice by RNA interference
-
Ge Q, Filip L, Bai A, Nguyen T, Eisen HN, Chen J. 2004. Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc. Natl. Acad. Sci. USA 101:8676-81
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8676-8681
-
-
Ge, Q.1
Filip, L.2
Bai, A.3
Nguyen, T.4
Eisen, H.N.5
Chen, J.6
-
152
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from RNA interference- mediated inhibition
-
Das AT, Brummelkamp TR, Westerhout EM, Vink M, Madiredjo M, et al. 2004. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 78:2601-5
-
(2004)
J. Virol.
, vol.78
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
Vink, M.4
Madiredjo, M.5
-
153
-
-
0142124143
-
Human immunodeficiency virus type 1 escape from RNA interference
-
Boden D, Pusch O, Lee F, Tucker L, Ramratnam B. 2003. Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 77:11531-35
-
(2003)
J. Virol.
, vol.77
, pp. 11531-11535
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Ramratnam, B.5
-
154
-
-
0042265526
-
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
-
Wang X, Huong SM, Chiu ML, Raab-Traub N, Huang ES. 2003. Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus. Nature 424:456-61
-
(2003)
Nature
, vol.424
, pp. 456-461
-
-
Wang, X.1
Huong, S.M.2
Chiu, M.L.3
Raab-Traub, N.4
Huang, E.S.5
-
155
-
-
0038610713
-
Caspase 8 small interfering RNA prevents acute liver failure in mice
-
Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, et al. 2003. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc. Natl. Acad. Sci. USA 100:7797-802
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7797-7802
-
-
Zender, L.1
Hutker, S.2
Liedtke, C.3
Tillmann, H.L.4
Zender, S.5
-
156
-
-
0345826094
-
BACE1 suppression by RNA interference in primary cortical neurons
-
Kao SC, Krichevsky AM, Kosik KS, Tsai LH. 2004. BACE1 suppression by RNA interference in primary cortical neurons. J. Biol. Chem. 279:1942-49
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1942-1949
-
-
Kao, S.C.1
Krichevsky, A.M.2
Kosik, K.S.3
Tsai, L.H.4
-
157
-
-
0038578675
-
Efficient and specific down-regulation of prion protein expression by RNAi
-
Tilly G, Chapuis J, Vilette D, Laude H, Vilotte JL. 2003. Efficient and specific down-regulation of prion protein expression by RNAi. Biochem. Biophys. Res. Commun. 305:548-51
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 548-551
-
-
Tilly, G.1
Chapuis, J.2
Vilette, D.3
Laude, H.4
Vilotte, J.L.5
-
158
-
-
0344926320
-
Cationic liposome-mediated delivery of siRNAs in adult mice
-
Sioud M, Sorensen DR. 2003. Cationic liposome-mediated delivery of siRNAs in adult mice. Biochem. Biophys. Res. Commun. 312:1220-25
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 1220-1225
-
-
Sioud, M.1
Sorensen, D.R.2
-
159
-
-
0141595996
-
Linear polyethylenimine as a tool for comparative studies of antisense and short double-stranded RNA oligonucleotides
-
Bologna JC, Dorn G, Natt F, Weiler J. 2003. Linear polyethylenimine as a tool for comparative studies of antisense and short double-stranded RNA oligonucleotides. Nucleosides Nucleotides Nucleic Acids 22:1729-31
-
(2003)
Nucleosides Nucleotides Nucleic Acids
, vol.22
, pp. 1729-1731
-
-
Bologna, J.C.1
Dorn, G.2
Natt, F.3
Weiler, J.4
-
160
-
-
2342593280
-
Surfection: A new platform for transfected cell arrays
-
Chang FH, Lee CH, Chen MT, Kuo CC, Chiang YL, et al. 2004. Surfection: a new platform for transfected cell arrays. Nucleic Acids Res. 32:e33
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Chang, F.H.1
Lee, C.H.2
Chen, M.T.3
Kuo, C.C.4
Chiang, Y.L.5
-
161
-
-
0037769876
-
Immune modulation by silencing IL-12 production in dendritic cells using small interfering RNA
-
Hill JA, Ichim TE, Kusznieruk KP, Li M, Huang X, et al. 2003. Immune modulation by silencing IL-12 production in dendritic cells using small interfering RNA. J. Immunol. 171:691-96
-
(2003)
J. Immunol.
, vol.171
, pp. 691-696
-
-
Hill, J.A.1
Ichim, T.E.2
Kusznieruk, K.P.3
Li, M.4
Huang, X.5
-
162
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, von Kalle C, Schmidt M, Le Deist F, Wulffraat N, et al. 2003. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348:255-56
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
Le Deist, F.4
Wulffraat, N.5
-
163
-
-
0038303229
-
Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin
-
Wang J, Tekle E, Oubrahim H, Mieyal JJ, Stadtman ER, Chock PB. 2003. Stable and controllable RNA interference: investigating the physiological function of glutathionylated actin. Proc. Natl. Acad. Sci. USA 100:5103-6
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5103-5106
-
-
Wang, J.1
Tekle, E.2
Oubrahim, H.3
Mieyal, J.J.4
Stadtman, E.R.5
Chock, P.B.6
-
164
-
-
0042941765
-
Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
-
Chen Y, Stamatoyannopoulos G, Song CZ. 2003. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res. 63:4801-4
-
(2003)
Cancer Res.
, vol.63
, pp. 4801-4804
-
-
Chen, Y.1
Stamatoyannopoulos, G.2
Song, C.Z.3
-
165
-
-
0642303887
-
Inducible shRNA expression for application in a prostate cancer mouse model
-
Czauderna F, Santel A, Hinz M, Fechtner M, Durieux B, et al. 2003. Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res. 31:e127
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Czauderna, F.1
Santel, A.2
Hinz, M.3
Fechtner, M.4
Durieux, B.5
-
166
-
-
0043210428
-
Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
-
Wiznerowicz M, Trono D. 2003. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77:8957-61
-
(2003)
J. Virol.
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
-
167
-
-
0042662862
-
Establishment of conditional vectors for hairpin siRNA knockdowns
-
Matsukura S, Jones PA, Takai D. 2003. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res. 31:e77
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Matsukura, S.1
Jones, P.A.2
Takai, D.3
-
168
-
-
10744219596
-
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
-
van de Watering M, Oving I, Muncan V, Pon Fong MT, Brantjes H, et al. 2003. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep. 4:609-15
-
(2003)
EMBO Rep.
, vol.4
, pp. 609-615
-
-
Van De Watering, M.1
Oving, I.2
Muncan, V.3
Pon Fong, M.T.4
Brantjes, H.5
-
170
-
-
3142708570
-
Crelox-regulated conditional RNA interference from transgenes
-
Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, et al. 2004. Crelox-regulated conditional RNA interference from transgenes. Proc. Natl. Acad. Sci. USA 101:10380-85
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
-
171
-
-
0142150130
-
Control of siRNA expression utilizing Cre-loxP recombination system
-
Kasim V, Miyagishi M, Taira K. 2003. Control of siRNA expression utilizing Cre-loxP recombination system. Nucleic Acids Res. Suppl. 3:255-56
-
(2003)
Nucleic Acids Res. Suppl.
, vol.3
, pp. 255-256
-
-
Kasim, V.1
Miyagishi, M.2
Taira, K.3
-
172
-
-
1642487123
-
Conditional gene knock-down by CRE-dependent short interfering RNAs
-
Fritsch L, Martinez LA, Sekhri R, Naguibneva I, Gerard M, et al. 2004. Conditional gene knock-down by CRE-dependent short interfering RNAs. EMBO Rep. 5:178-82
-
(2004)
EMBO Rep.
, vol.5
, pp. 178-182
-
-
Fritsch, L.1
Martinez, L.A.2
Sekhri, R.3
Naguibneva, I.4
Gerard, M.5
-
173
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta S, Schoer RA, Egan JE, Hannon GJ, Mittal V. 2004. Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl. Acad. Sci. USA 101:1927-32
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
174
-
-
0038725897
-
Genome-wide RNAi screening in Caenorhabditis elegans
-
Kamath RS, Ahringer J. 2003. Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30:313-21
-
(2003)
Methods
, vol.30
, pp. 313-321
-
-
Kamath, R.S.1
Ahringer, J.2
-
175
-
-
0037137443
-
Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans
-
Piano F, Schetter AJ, Morton DG, Gunsalus KC, Reinke V, et al. 2002. Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr. Biol. 12:1959-64
-
(2002)
Curr. Biol.
, vol.12
, pp. 1959-1964
-
-
Piano, F.1
Schetter, A.J.2
Morton, D.G.3
Gunsalus, K.C.4
Reinke, V.5
-
176
-
-
0036445530
-
Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication
-
Yamamoto T, Omoto S, Mizuguchi M, Mizukami H, Okuyama H, et al. 2002. Double-stranded nef RNA interferes with human immunodeficiency virus type 1 replication. Microbiol. Immunol. 46:809-17
-
(2002)
Microbiol. Immunol.
, vol.46
, pp. 809-817
-
-
Yamamoto, T.1
Omoto, S.2
Mizuguchi, M.3
Mizukami, H.4
Okuyama, H.5
-
177
-
-
0037112667
-
Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference
-
Park WS, Miyano-Kurosaki N, Hayafune M, Nakajima E, Matsuzaki T, et al. 2002. Prevention of HIV-1 infection in human peripheral blood mononuclear cells by specific RNA interference. Nucleic Acids Res. 30:4830-35
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 4830-4835
-
-
Park, W.S.1
Miyano-Kurosaki, N.2
Hayafune, M.3
Nakajima, E.4
Matsuzaki, T.5
-
178
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici J, Kariko K, Weissman D. 2002. Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J. Immunol 169:5196-201
-
(2002)
J. Immunol.
, vol.169
, pp. 5196-5201
-
-
Capodici, J.1
Kariko, K.2
Weissman, D.3
-
179
-
-
1642452660
-
Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
-
Nishitsuji H, Ikeda T, Miyoshi H, Ohashi T, Kannagi M, Masuda T. 2004. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microb. Infect. 6:76-85
-
(2004)
Microb. Infect.
, vol.6
, pp. 76-85
-
-
Nishitsuji, H.1
Ikeda, T.2
Miyoshi, H.3
Ohashi, T.4
Kannagi, M.5
Masuda, T.6
-
180
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS, Dohjima T, Bauer G, Li H, Li MJ, et al. 2002. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20:500-5
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
Li, H.4
Li, M.J.5
-
181
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn GA, Cullen BR. 2002. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol. 76:9225-31
-
(2002)
J. Virol.
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
182
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque JM, Triques K, Stevenson M. 2002. Modulation of HIV-1 replication by RNA interference. Nature 418:435-38
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.M.1
Triques, K.2
Stevenson, M.3
-
184
-
-
0242440877
-
Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells
-
Park WS, Hayafune M, Miyano-Kurosaki N, Takaku H. 2003. Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells. Gene Ther. 10:2046-50
-
(2003)
Gene Ther.
, vol.10
, pp. 2046-2050
-
-
Park, W.S.1
Hayafune, M.2
Miyano-Kurosaki, N.3
Takaku, H.4
-
185
-
-
0036066508
-
siRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, et al. 2002. siRNA-directed inhibition of HIV-1 infection. Nat. Med. 8:681-86
-
(2002)
Nat. Med.
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
Beresford, P.J.4
Riess, J.5
-
186
-
-
0242300128
-
Protection from HIV-1 infection of primary CD4 T cells by CCR5 silencing is effective for the full spectrum of CCR5 expression
-
Butticaz C, Ciuffi A, Munoz M, Thomas J, Bridge A, et al. 2003. Protection from HIV-1 infection of primary CD4 T cells by CCR5 silencing is effective for the full spectrum of CCR5 expression. Antiviral. Ther. 8:373-77
-
(2003)
Antiviral. Ther.
, vol.8
, pp. 373-377
-
-
Butticaz, C.1
Ciuffi, A.2
Munoz, M.3
Thomas, J.4
Bridge, A.5
-
187
-
-
0037032933
-
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
-
Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, et al. 2002. Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16:2385-90
-
(2002)
AIDS
, vol.16
, pp. 2385-2390
-
-
Martinez, M.A.1
Gutierrez, A.2
Armand-Ugon, M.3
Blanco, J.4
Parera, M.5
-
189
-
-
1242342082
-
Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1)
-
Chiu YL, Cao H, Jacque JM, Stevenson M, Rana TM. 2004. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J. Virol. 78:2517-29
-
(2004)
J. Virol.
, vol.78
, pp. 2517-2529
-
-
Chiu, Y.L.1
Cao, H.2
Jacque, J.M.3
Stevenson, M.4
Rana, T.M.5
-
190
-
-
1642564331
-
Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance
-
Anderson J, Banerjea A, Akkina R. 2003. Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides 13:303-12
-
(2003)
Oligonucleotides
, vol.13
, pp. 303-312
-
-
Anderson, J.1
Banerjea, A.2
Akkina, R.3
-
191
-
-
0037382795
-
Inhibition of hepatitis B virus expression and replication by RNA interference
-
Shlomai A, Shaul Y. 2003. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology 37:764-70
-
(2003)
Hepatology
, vol.37
, pp. 764-770
-
-
Shlomai, A.1
Shaul, Y.2
-
192
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, et al. 2003. Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol. 21:639-44
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
-
193
-
-
0041923781
-
Selective inhibition of hepatitis B virus replication by RNA interference
-
Ying C, De Clercq E, Neyts J. 2003. Selective inhibition of hepatitis B virus replication by RNA interference. Biochem. Biophys. Res. Commun. 309:482-84
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.309
, pp. 482-484
-
-
Ying, C.1
De Clercq, E.2
Neyts, J.3
-
194
-
-
0037382795
-
Inhibition of hepatitis B virus expression and replication by RNA interference. Interference of hepatitis C virus RNA replication by short interfering RNAs. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells
-
Shlomai A, Shaul Y, Kapadia SB, Brideau-Andersen A, Chisari FV, et al. 2003. Inhibition of hepatitis B virus expression and replication by RNA
-
(2003)
Hepatology
, vol.37
, pp. 764-770
-
-
Shlomai, A.1
Shaul, Y.2
Kapadia, S.B.3
Brideau-Andersen, A.4
Chisari, F.V.5
-
195
-
-
0037213594
-
Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7
-
Seo MY, Abrignani S, Houghton M, Han JH. 2003. Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7. J. Virol. 77:810-12
-
(2003)
J. Virol.
, vol.77
, pp. 810-812
-
-
Seo, M.Y.1
Abrignani, S.2
Houghton, M.3
Han, J.H.4
-
196
-
-
0142091755
-
Inhibition of hepatitis C virus protein expression by RNA interference
-
Sen A, Steele R, Ghosh AK, Basu A, Ray R, Ray RB. 2003. Inhibition of hepatitis C virus protein expression by RNA interference. Virus Res. 96:27-35
-
(2003)
Virus Res.
, vol.96
, pp. 27-35
-
-
Sen, A.1
Steele, R.2
Ghosh, A.K.3
Basu, A.4
Ray, R.5
Ray, R.B.6
-
197
-
-
0041387358
-
Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action
-
Chang J, Taylor JM. 2003. Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action. J. Virol. 77:9728-31
-
(2003)
J. Virol.
, vol.77
, pp. 9728-9731
-
-
Chang, J.1
Taylor, J.M.2
-
198
-
-
1642544563
-
Inhibition of human cytomegalovirus replication by small interfering RNAs
-
Wiebusch L, Truss M, Hagemeier C. 2004. Inhibition of human cytomegalovirus replication by small interfering RNAs. J. Gen. Virol. 85:179-84
-
(2004)
J. Gen. Virol.
, vol.85
, pp. 179-184
-
-
Wiebusch, L.1
Truss, M.2
Hagemeier, C.3
-
199
-
-
0345547464
-
Small interfering RNA molecules as potential anti-human rhinovirus agents: In vitro potency, specificity, and mechanism
-
Phipps KM, Martinez A, Lu J, Heinz BA, Zhao G. 2004. Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism. Antiviral. Res. 61:49-55
-
(2004)
Antiviral. Res.
, vol.61
, pp. 49-55
-
-
Phipps, K.M.1
Martinez, A.2
Lu, J.3
Heinz, B.A.4
Zhao, G.5
-
200
-
-
0037372313
-
Inhibition of gamma-herpesvirus replication by RNA interference
-
Jia Q, Sun R. 2003. Inhibition of gamma-herpesvirus replication by RNA interference. J. Virol. 77:3301-6
-
(2003)
J. Virol.
, vol.77
, pp. 3301-3306
-
-
Jia, Q.1
Sun, R.2
-
201
-
-
1542267797
-
RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells
-
Maxwell MM, Pasinelli P, Kazantsev AG, Brown RH Jr. 2004. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells. Proc. Natl. Acad. Sci. USA 101:3178-83
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3178-3183
-
-
Maxwell, M.M.1
Pasinelli, P.2
Kazantsev, A.G.3
Brown Jr., R.H.4
-
202
-
-
0141886425
-
Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference
-
Abdelgany A, Wood M, Beeson D. 2003. Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference. Hum. Mol. Genet. 12:2637-44
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2637-2644
-
-
Abdelgany, A.1
Wood, M.2
Beeson, D.3
-
203
-
-
0042847060
-
Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells
-
Grzmil M, Thelen P, Hemmerlein B, Schweyer S, Voigt S, et al. 2003. Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells. Am. J. Pathol. 163:543-52
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 543-552
-
-
Grzmil, M.1
Thelen, P.2
Hemmerlein, B.3
Schweyer, S.4
Voigt, S.5
-
204
-
-
1442308345
-
EphA2: A determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. 2004. EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene 23:1448-56
-
(2004)
Oncogene
, vol.23
, pp. 1448-1456
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
205
-
-
0141480922
-
Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells
-
Sanceau J, Truchet S, Bauvois B. 2003. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells. J. Biol. Chem. 278:36537-46
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36537-36546
-
-
Sanceau, J.1
Truchet, S.2
Bauvois, B.3
-
206
-
-
0038047685
-
AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells
-
Heidenreich O, Krauter J, Riehle H, Hadwiger P, John M, et al. 2003. AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells. Blood 101:3157-63
-
(2003)
Blood
, vol.101
, pp. 3157-3163
-
-
Heidenreich, O.1
Krauter, J.2
Riehle, H.3
Hadwiger, P.4
John, M.5
-
207
-
-
0141816881
-
Suppression of BRAF(V599E) in human melanoma abrogates transformation
-
Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA. 2003. Suppression of BRAF(V599E) in human melanoma abrogates transformation. Cancer Res. 63:5198-202
-
(2003)
Cancer Res.
, vol.63
, pp. 5198-5202
-
-
Hingorani, S.R.1
Jacobetz, M.A.2
Robertson, G.P.3
Herlyn, M.4
Tuveson, D.A.5
-
208
-
-
0042786007
-
Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation
-
Harvey AJ, Crompton MR. 2003. Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation. Oncogene 22:5006-10
-
(2003)
Oncogene
, vol.22
, pp. 5006-5010
-
-
Harvey, A.J.1
Crompton, M.R.2
-
209
-
-
0842329646
-
Suppression of Epstein-Barr virus-encoded latent membrane protein-1 by RNA interference inhibits the metastatic potential of nasopharyngeal carcinoma cells
-
Li XP, Li G, Peng Y, Kung HF, Lin MC. 2004. Suppression of Epstein-Barr virus-encoded latent membrane protein-1 by RNA interference inhibits the metastatic potential of nasopharyngeal carcinoma cells. Biochem. Biophys. Res. Commun. 315:212-18
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.315
, pp. 212-218
-
-
Li, X.P.1
Li, G.2
Peng, Y.3
Kung, H.F.4
Lin, M.C.5
-
210
-
-
0037446068
-
Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells
-
Nagy P, Arndt-Jovin DJ, Jovin TM. 2003. Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells. Exp. Cell Res. 285:39-49
-
(2003)
Exp. Cell Res.
, vol.285
, pp. 39-49
-
-
Nagy, P.1
Arndt-Jovin, D.J.2
Jovin, T.M.3
-
211
-
-
0345763126
-
Inhibition of epidermal growth factor receptor expression by RNA interference in A549 cells
-
Zhang M, Zhang X, Bai CX, Chen J, Wei MQ. 2004. Inhibition of epidermal growth factor receptor expression by RNA interference in A549 cells. Acta Pharmacol. Sin. 25:61-67
-
(2004)
Acta Pharmacol. Sin.
, vol.25
, pp. 61-67
-
-
Zhang, M.1
Zhang, X.2
Bai, C.X.3
Chen, J.4
Wei, M.Q.5
-
212
-
-
0038418257
-
RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells
-
De Schrijver E, Brusselmans K, Heyns W, Verhoeven G, Swinnen JV. 2003. RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells. Cancer Res. 63:3799-804
-
(2003)
Cancer Res.
, vol.63
, pp. 3799-3804
-
-
De Schrijver, E.1
Brusselmans, K.2
Heyns, W.3
Verhoeven, G.4
Swinnen, J.V.5
-
213
-
-
0344873763
-
Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene
-
Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. 2003. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene 22:8330-36
-
(2003)
Oncogene
, vol.22
, pp. 8330-8336
-
-
Crnkovic-Mertens, I.1
Hoppe-Seyler, F.2
Butz, K.3
-
214
-
-
0042318693
-
Induction of apoptosis in HeLa cells with siRNA expression vector targeted against bcl-2
-
Futami T, Miyagishi M, Seki M, Taira K. 2002. Induction of apoptosis in HeLa cells with siRNA expression vector targeted against bcl-2. Nucleic Acids Res. Suppl. 2:251-52
-
(2002)
Nucleic Acids Res. Suppl.
, vol.2
, pp. 251-252
-
-
Futami, T.1
Miyagishi, M.2
Seki, M.3
Taira, K.4
-
215
-
-
0037132736
-
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
-
Spankuch-Schmitt B, Bereiter-Hahn J, Kaufmann M, Strebhardt K. 2002. Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells. J. Natl. Cancer Inst. 94:1863-77
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1863-1877
-
-
Spankuch-Schmitt, B.1
Bereiter-Hahn, J.2
Kaufmann, M.3
Strebhardt, K.4
-
217
-
-
0347087458
-
RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells
-
Zhang L, Fogg DK, Waisman DM. 2004. RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells. J. Biol. Chem. 279:2053-62
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2053-2062
-
-
Zhang, L.1
Fogg, D.K.2
Waisman, D.M.3
-
218
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
Konnikova L, Kotecki M, Kruger MM, Cochran BH. 2003. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 3:23
-
(2003)
BMC Cancer
, vol.3
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
219
-
-
1642523434
-
Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL)
-
Ritter U, Damm-Welk C, Fuchs U, Bohle RM, Borkhardt A, Woessmann W. 2003. Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL). Oligonucleotides 13:365-73
-
(2003)
Oligonucleotides
, vol.13
, pp. 365-373
-
-
Ritter, U.1
Damm-Welk, C.2
Fuchs, U.3
Bohle, R.M.4
Borkhardt, A.5
Woessmann, W.6
|