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Volumn 1, Issue 9, 2002, Pages 727-730

The druggable genome

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; DNA VACCINE; G PROTEIN COUPLED RECEPTOR; HORMONE RECEPTOR; METALLOPROTEINASE; PHOSPHODIESTERASE; PROTEIN DERIVATIVE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; SERINE PROTEINASE;

EID: 0036717194     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd892     Document Type: Article
Times cited : (2860)

References (16)
  • 1
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski, C., Lombardo, F., Dominy, B. & Feeney, P. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 23, 3-25 (1997).
    • (1997) Adv. Drug Deliv. Rev. , vol.23 , pp. 3-25
    • Lipinski, C.1    Lombardo, F.2    Dominy, B.3    Feeney, P.4
  • 2
    • 0030274647 scopus 로고    scopus 로고
    • Genomic sciences and the medicine of tomorrow
    • Drews, J. Genomic sciences and the medicine of tomorrow. Nature Biotechnol. 14, 1516-1518 (1996).
    • (1996) Nature Biotechnol. , vol.14 , pp. 1516-1518
    • Drews, J.1
  • 3
    • 0031304155 scopus 로고    scopus 로고
    • Classic drug targets
    • Drews, J. & Ryser, S. Classic drug targets. Nature Biotechnol. 15, 1318-1319 (1997).
    • (1997) Nature Biotechnol. , vol.15 , pp. 1318-1319
    • Drews, J.1    Ryser, S.2
  • 4
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: A historical perspective
    • Drews, J. Drug discovery: a historical perspective. Science 287, 1960-1964 (2000).
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.1
  • 5
    • 0035286796 scopus 로고    scopus 로고
    • The end of the beginning for genomic medicine
    • Bailey, D., Zanders, E. & Dean, P. The end of the beginning for genomic medicine. Nature Biotechnol. 19, 207-209 (2001).
    • (2001) Nature Biotechnol. , vol.19 , pp. 207-209
    • Bailey, D.1    Zanders, E.2    Dean, P.3
  • 6
    • 0035166973 scopus 로고    scopus 로고
    • The InterPro database, an integrated documentation resource for protein families, domains and functional sites
    • Apweiler, R. et al. The InterPro database, an integrated documentation resource for protein families, domains and functional sites. Nucleic Acids Res. 29, 37-40 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. 37-40
    • Apweiler, R.1
  • 7
    • 85039625749 scopus 로고    scopus 로고
    • Proteome Analysis Database [online], (version analysed with release date 29 Oct 01)
    • Proteome Analysis Database [online], (version analysed with release date 29 Oct 01) http://www.ebi.ac.uk/proteome/ (2001).
    • (2001)
  • 8
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander, E. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.1
  • 9
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter, J. C. et al. The sequence of the human genome. Science 291, 1304-1351 (2001).
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1
  • 10
    • 0031686598 scopus 로고    scopus 로고
    • Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool ('metabolome') analysis
    • Tweeddale, H., Notley-McRobb, L. & Ferenci, T. Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool ('metabolome') analysis. J. Bacteriol. 180, 5109-5119 (1998).
    • (1998) J. Bacteriol. , vol.180 , pp. 5109-5119
    • Tweeddale, H.1    Notley-McRobb, L.2    Ferenci, T.3
  • 11
    • 0033757963 scopus 로고    scopus 로고
    • Metabolite profiling for plant functional genomics
    • Fiehn, O. et al. Metabolite profiling for plant functional genomics. Nature Biotechnol. 18, 1157-1161 (2000).
    • (2000) Nature Biotechnol. , vol.18 , pp. 1157-1161
    • Fiehn, O.1
  • 12
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
    • Raamsdonk, L. et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nature Biotechnol. 19, 45-50 (2001).
    • (2001) Nature Biotechnol. , vol.19 , pp. 45-50
    • Raamsdonk, L.1
  • 13
    • 0035895513 scopus 로고    scopus 로고
    • What if there are only 30,000 human genes?
    • Claverie, J.-M. What if there are only 30,000 human genes? Science 291, 1255-1257 (2001).
    • (2001) Science , vol.291 , pp. 1255-1257
    • Claverie, J.-M.1
  • 14
    • 0035711462 scopus 로고    scopus 로고
    • In vivo drug target discovery: Identifying the best targets from the genome
    • Walke, D. W. et al. In vivo drug target discovery: identifying the best targets from the genome. Curr. Opin, Biotechnol. 12, 626-631 (2001)
    • (2001) Curr. Opin. Biotechnol. , vol.12 , pp. 626-631
    • Walke, D.W.1
  • 15
    • 0003951725 scopus 로고    scopus 로고
    • Lehman Brothers. (Lehman Brothers)
    • Lehman Brothers. The Fruits of Genomics (Lehman Brothers, 2001).
    • (2001) The Fruits of Genomics
  • 16
    • 0034708444 scopus 로고    scopus 로고
    • Comparative genomics of the eukaryotes
    • Rubin, G. Comparative genomics of the eukaryotes. Science 24, 2204-2215 (2000).
    • (2000) Science , vol.24 , pp. 2204-2215
    • Rubin, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.