A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens

Nucleic Acids Research

Volumn 32, Issue 3, 2004, Pages 893-901

  Hsieh, Andrew C ^a,d   Bo, Ronghai ^a   Manola, Judith ^a   Vazquez, Francisca ^a   Bare, Olivia ^a   Khvorova, Anastasia ^c   Scaringe, Stephen ^c   Sellers, William R ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Dharmacon Inc   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DOUBLE STRANDED RNA; GUANINE; MESSENGER RNA; NUCLEOTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SERINE; THYMINE; AKT1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DATA ANALYSIS; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE LIBRARY; GENE SEQUENCE; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC CODE; GENETIC PARAMETERS; GENETIC REGULATION; GENETIC SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MAMMAL CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA SYNTHESIS; CELL LINE; GENETICS; METABOLISM; PHENOTYPE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNTHESIS;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE; GENE TARGETING; HUMANS; PHENOTYPE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 2342564353     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh238     Document Type: Article

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