메뉴 건너뛰기




Volumn 432, Issue 7020, 2004, Pages 1036-1040

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; GENES; INTERFERONS; RNA;

EID: 19944367565     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03159     Document Type: Article
Times cited : (353)

References (30)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1
  • 2
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein, E., Gaudy, A. A., Hammond, S. M. & Hannon, G. J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366 (2001).
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Gaudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 3
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S. M., Lendeckel, W. & Tuschl, T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15, 188-200 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 4
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez, J., Patkaniowska, A., Urlaub, H., Luhrmann, R. & Tuschl, T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574 (2002).
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 5
    • 0034676448 scopus 로고    scopus 로고
    • Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
    • Gonczy, P. et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408, 331-336 (2000).
    • (2000) Nature , vol.408 , pp. 331-336
    • Gonczy, P.1
  • 6
    • 0034676457 scopus 로고    scopus 로고
    • Functional genomic analysis of C. elegans chromosome 1 by systematic RNA interference
    • Fraser, A. G. et al. Functional genomic analysis of C. elegans chromosome 1 by systematic RNA interference. Nature 408, 325-330 (2000).
    • (2000) Nature , vol.408 , pp. 325-330
    • Fraser, A.G.1
  • 7
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath, R. S. et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421, 231-237 (2003).
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1
  • 8
    • 0842309871 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of growth and viability in Drosophila cells
    • Boutros, M. et al. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303, 832-835 (2004).
    • (2004) Science , vol.303 , pp. 832-835
    • Boutros, M.1
  • 9
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M. et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498 (2001).
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1
  • 10
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J. & Conklin, D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 11
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T. R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 12
    • 0037162522 scopus 로고    scopus 로고
    • Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    • Yang, D. et al. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc. Natl Acad. Sci. USA 99, 9942-9947 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 9942-9947
    • Yang, D.1
  • 13
    • 0347089019 scopus 로고    scopus 로고
    • An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
    • Zheng, L. et al. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl Acad. Sci. USA 101, 135-140 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 135-140
    • Zheng, L.1
  • 14
    • 12144289681 scopus 로고    scopus 로고
    • A large-scale RNAi screen in human cells identifies new components of the p53 pathway
    • Berns, K. et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437 (2004).
    • (2004) Nature , vol.428 , pp. 431-437
    • Berns, K.1
  • 15
    • 12144288006 scopus 로고    scopus 로고
    • A resource for large-scale RNA-interference-based screens in mammals
    • Paddison, P. J. et al. A resource for large-scale RNA-interference-based screens in mammals. Nature 428, 427-431 (2004).
    • (2004) Nature , vol.428 , pp. 427-431
    • Paddison, P.J.1
  • 16
    • 0037195064 scopus 로고    scopus 로고
    • Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA
    • Calegari, F., Haubensak, W., Yang, D., Huttner, W. B. & Buchholz, F. Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proc. Natl Acad. Sci. USA 99, 14236-14240 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14236-14240
    • Calegari, F.1    Haubensak, W.2    Yang, D.3    Huttner, W.B.4    Buchholz, F.5
  • 17
    • 12144289381 scopus 로고    scopus 로고
    • Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
    • Kronke, J. et al. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J. Virol. 78, 3436-3446 (2004).
    • (2004) J. Virol. , vol.78 , pp. 3436-3446
    • Kronke, J.1
  • 18
    • 3242891277 scopus 로고    scopus 로고
    • DEQOR a web-based tool for the design and quality control of siRNAs
    • Henschel, A., Buchholz, F. & Habermann, B. DEQOR: a web-based tool for the design and quality control of siRNAs. Nucleic Acids Res. 32, W113-W120 (2004).
    • (2004) Nucleic Acids Res. , vol.32
    • Henschel, A.1    Buchholz, F.2    Habermann, B.3
  • 19
    • 4444231522 scopus 로고    scopus 로고
    • 'Harvester': A fast meta search engine of human protein resources
    • Liebel, U., Kindler, B. & Pepperkok, R. 'Harvester': a fast meta search engine of human protein resources. Bioinformatics 20, 1962-1963 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 1962-1963
    • Liebel, U.1    Kindler, B.2    Pepperkok, R.3
  • 20
    • 0029417238 scopus 로고
    • Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • Blangy, A. et al. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83, 1159-1169 (1995).
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1
  • 21
    • 0035694237 scopus 로고    scopus 로고
    • Identification of essential genes in cultured mammalian cells using small interfering RNAs
    • Harborth, J., Elbashir, S. M., Bechert, K., Tuscht, T. & Weber, K. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114, 4557-4565 (2001).
    • (2001) J. Cell Sci. , vol.114 , pp. 4557-4565
    • Harborth, J.1    Elbashir, S.M.2    Bechert, K.3    Tuscht, T.4    Weber, K.5
  • 22
    • 0037459085 scopus 로고    scopus 로고
    • Regulating access to the genome: Nucleocytoplasmic transport throughout the cell cycle
    • Weis, K. Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell 112, 441-451 (2003).
    • (2003) Cell , vol.112 , pp. 441-451
    • Weis, K.1
  • 23
    • 0034754698 scopus 로고    scopus 로고
    • Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae
    • Biggins, S., Bhalla, N., Chang, A., Smith, D. L. & Murray, A. W. Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159, 453-470 (2001).
    • (2001) Genetics , vol.159 , pp. 453-470
    • Biggins, S.1    Bhalla, N.2    Chang, A.3    Smith, D.L.4    Murray, A.W.5
  • 24
    • 0036143714 scopus 로고    scopus 로고
    • Removal of a single alpha-tubidin gene intron suppresses cell cycle arrest 'phenotypes of splicing factor mutations in Saccharomyces cerevisiae
    • Burns, C. G. et al. Removal of a single alpha-tubidin gene intron suppresses cell cycle arrest 'phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Mol Cell Biol 22, 801-815 (2002).
    • (2002) Mol. Cell Biol. , vol.22 , pp. 801-815
    • Burns, C.G.1
  • 25
    • 0037339967 scopus 로고    scopus 로고
    • Sequential entry of components of the gene expression machinery into daughter nuclei
    • Prasanth, K. V., Sacco-Bubuiya, P. A., Prasanth, S. G. & Spector, D. L. Sequential entry of components of the gene expression machinery into daughter nuclei. Mol Biol Cell 14, 1043-1057 (2003).
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1043-1057
    • Prasanth, K.V.1    Sacco-Bubuiya, P.A.2    Prasanth, S.G.3    Spector, D.L.4
  • 26
    • 0036849137 scopus 로고    scopus 로고
    • Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells
    • Gruss, O. J. et al. Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nature Cell Biol 4, 871-879 (2002).
    • (2002) Nature Cell Biol. , vol.4 , pp. 871-879
    • Gruss, O.J.1
  • 27
    • 0037073946 scopus 로고    scopus 로고
    • Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome
    • Makarov, E. M. et al. Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298, 2205-2208 (2002).
    • (2002) Science , vol.298 , pp. 2205-2208
    • Makarov, E.M.1
  • 28
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr, C. J. & Roberts, J. M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 29
    • 3242677639 scopus 로고    scopus 로고
    • siRNAs: Applications in functional genomics and potential as therapeutics
    • Dorsett, Y. & Tuschl, T. siRNAs: applications in functional genomics and potential as therapeutics. Nature Rev. Drug Discov. 3, 318-329 (2004).
    • (2004) Nature Rev. Drug Discov. , vol.3 , pp. 318-329
    • Dorsett, Y.1    Tuschl, T.2
  • 30
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson, A. L. et al. Expression profiling reveals off-target gene regulation by RNAi. Nature Biotechnol 21, 635-637 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 635-637
    • Jackson, A.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.