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Volumn 362, Issue 9393, 2003, Pages 1401-1403

Small RNA: Can RNA interference be exploited for therapy?

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE 8; DAUNORUBICIN; DOUBLE STRANDED RNA; DOXYCYCLINE; FAS ANTIGEN; INTERFERON; RNA; VIRUS VECTOR;

EID: 0242317385     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)14637-5     Document Type: Short Survey
Times cited : (172)

References (39)
  • 1
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature. 418:2002;244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 2
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore P.D., Tuschl T., Sharp P.A., Bartel D.P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 101:2000;25-33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 5
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson A.L., Bartz S.R., Schelter J., et al. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotech. 21:2003;635-637.
    • (2003) Nat Biotech , vol.21 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 6
    • 0034084338 scopus 로고    scopus 로고
    • Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
    • Gil J., Esteban M. Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis. 5:2000;107-114.
    • (2000) Apoptosis , vol.5 , pp. 107-114
    • Gil, J.1    Esteban, M.2
  • 7
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 8
    • 0038419800 scopus 로고    scopus 로고
    • Induction of an interferon response by RNAi vectors in mammalian cells
    • Bridge A.J., Pebernard S., Ducraux A., Nicoulaz A.L., Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet. 34:2003;263-264.
    • (2003) Nat Genet , vol.34 , pp. 263-264
    • Bridge, A.J.1    Pebernard, S.2    Ducraux, A.3    Nicoulaz, A.L.4    Iggo, R.5
  • 11
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 12
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison P.J., Caudy A.A., Bernstein E., Hannon G.J., Conklin D.S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:2002;948-958.
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 13
    • 0036787671 scopus 로고    scopus 로고
    • SiRNA-mediated gene silencing in vitro and in vivo
    • Xia H., Mao Q., Paulson H.L., Davidson B.L. SiRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol. 20:2002;1006-1010.
    • (2002) Nat Biotechnol , vol.20 , pp. 1006-1010
    • Xia, H.1    Mao, Q.2    Paulson, H.L.3    Davidson, B.L.4
  • 14
    • 0037948173 scopus 로고    scopus 로고
    • Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter
    • Shinagawa T., Shunsuke I. Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter. Genes Dev. 17:2003;1340-1345.
    • (2003) Genes Dev , vol.17 , pp. 1340-1345
    • Shinagawa, T.1    Shunsuke, I.2
  • 15
    • 0042662862 scopus 로고    scopus 로고
    • Establishment of conditional vectors for hairpin siRNA knockdowns
    • Matsukura S., Jones P.A., Takai D. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res. 31:2003;e77.
    • (2003) Nucleic Acids Res , vol.31 , pp. 77
    • Matsukura, S.1    Jones, P.A.2    Takai, D.3
  • 16
    • 0042941765 scopus 로고    scopus 로고
    • Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
    • Chen Y., Stamatoyannopoulos G., Song C.Z. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res. 63:2003;4801-4804.
    • (2003) Cancer Res , vol.63 , pp. 4801-4804
    • Chen, Y.1    Stamatoyannopoulos, G.2    Song, C.Z.3
  • 17
    • 0038303229 scopus 로고    scopus 로고
    • Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin
    • Wang J., Tekle E., Oubrahim H., Mieyal J.J., Stadtman E.R., Chock P.B. Stable and controllable RNA interference: investigating the physiological function of glutathionylated actin. Proc Nat Acad Sci USA. 100:2003;5103-5106.
    • (2003) Proc Nat Acad Sci USA , vol.100 , pp. 5103-5106
    • Wang, J.1    Tekle, E.2    Oubrahim, H.3    Mieyal, J.J.4    Stadtman, E.R.5    Chock, P.B.6
  • 18
    • 10744219596 scopus 로고    scopus 로고
    • Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
    • Van de Wetering M., Oving I., Muncan V., et al. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep. 4:2003;609-615.
    • (2003) EMBO Rep , vol.4 , pp. 609-615
    • Van De Wetering, M.1    Oving, I.2    Muncan, V.3
  • 19
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson D.A., Dillon C.P., Kwiatkowski A.V., et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet. 33:2003;401-406.
    • (2003) Nat Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 21
    • 0036904741 scopus 로고    scopus 로고
    • Intravascular adenoviral agents in cancer patients: Lessons from clinical trials
    • Reid T., Warren R., Kirn D. Intravascular adenoviral agents in cancer patients: lessons from clinical trials. Cancer Gene Ther. 9:2002;979-986.
    • (2002) Cancer Gene Ther , vol.9 , pp. 979-986
    • Reid, T.1    Warren, R.2    Kirn, D.3
  • 22
  • 23
    • 0037012663 scopus 로고    scopus 로고
    • Antisense-RNA regulation and RNA interference
    • Brantl S. Antisense-RNA regulation and RNA interference. Biochmica Biophysica Acta. 1575:2002;15-25.
    • (2002) Biochmica Biophysica Acta , vol.1575 , pp. 15-25
    • Brantl, S.1
  • 24
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E., Lee S.K., Wang J., et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med. 9:2001;347-351.
    • (2001) Nat Med , vol.9 , pp. 347-351
    • Song, E.1    Lee, S.K.2    Wang, J.3
  • 25
    • 0038610713 scopus 로고    scopus 로고
    • Caspase 8 small interfering RNA prevents acute liver failure in mice
    • Zender L., Hutker S., Liedtke C., et al. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Nat Acad Sci USA. 100:2003;7797-7802.
    • (2003) Proc Nat Acad Sci USA , vol.100 , pp. 7797-7802
    • Zender, L.1    Hutker, S.2    Liedtke, C.3
  • 26
    • 0036721314 scopus 로고    scopus 로고
    • Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
    • Covurn G.A., Cullen B.R. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol. 76:2002;9225-9231.
    • (2002) J Virol , vol.76 , pp. 9225-9231
    • Covurn, G.A.1    Cullen, B.R.2
  • 27
    • 0037418322 scopus 로고    scopus 로고
    • RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
    • Ge Q., McManus M.T., Nguyen T., et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Nat Acad Sci USA. 100:2003;2718-2723.
    • (2003) Proc Nat Acad Sci USA , vol.100 , pp. 2718-2723
    • Ge, Q.1    McManus, M.T.2    Nguyen, T.3
  • 28
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp T.R., Bernards R., Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell. 2:2002;243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 29
    • 0242379146 scopus 로고    scopus 로고
    • Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
    • Ding H., Schwarz D.S., Keene A., et al. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell. 2:2003;209-217.
    • (2003) Aging Cell , vol.2 , pp. 209-217
    • Ding, H.1    Schwarz, D.S.2    Keene, A.3
  • 30
    • 0141790842 scopus 로고    scopus 로고
    • Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571)
    • Wohlbold L., Van Der Kuip H., et al. Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571). Blood. 102:2003;2236-2239.
    • (2003) Blood , vol.102 , pp. 2236-2239
    • Wohlbold, L.1    Van Der Kuip, H.2
  • 31
    • 0037441756 scopus 로고    scopus 로고
    • Specific inhibition of bcr-abl gene expression by small interfering RNA
    • Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., Eder M. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood. 101:2003;1566-1569.
    • (2003) Blood , vol.101 , pp. 1566-1569
    • Scherr, M.1    Battmer, K.2    Winkler, T.3    Heidenreich, O.4    Ganser, A.5    Eder, M.6
  • 32
    • 0037158901 scopus 로고    scopus 로고
    • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
    • Wilda M., Fuchs U., Wossmann W., Borkhardt A. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene. 21:2002;5716-5724.
    • (2002) Oncogene , vol.21 , pp. 5716-5724
    • Wilda, M.1    Fuchs, U.2    Wossmann, W.3    Borkhardt, A.4
  • 34
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath R.S., Fraser A.G., Dong Y., et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 421:2003;231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2    Dong, Y.3
  • 35
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashrafi K., Chang F.Y., Watts J.L., et al. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature. 421:2003;268-272.
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3
  • 36
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee S.S., Lee R.Y., Fraser A.G., Kamath R.S., Ahringer J., Ruvkun G. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet. 33:2003;40-48.
    • (2003) Nat Genet , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 37
    • 0037443054 scopus 로고    scopus 로고
    • Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
    • Pothof J., Van Haaften G., Thijssen K., et al. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev. 17:2003;443-448.
    • (2003) Genes Dev , vol.17 , pp. 443-448
    • Pothof, J.1    Van Haaften, G.2    Thijssen, K.3
  • 38
    • 0042467554 scopus 로고    scopus 로고
    • Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
    • Brummelkamp T.R., Nijman S.M., Dirac A.M., Bernards R. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB. Nature. 424:2003;797-801.
    • (2003) Nature , vol.424 , pp. 797-801
    • Brummelkamp, T.R.1    Nijman, S.M.2    Dirac, A.M.3    Bernards, R.4
  • 39
    • 0037441979 scopus 로고    scopus 로고
    • Consortium uses RNAi to uncover genes' function
    • Frankish H. Consortium uses RNAi to uncover genes' function. Lancet. 361:2003;584.
    • (2003) Lancet , vol.361 , pp. 584
    • Frankish, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.