A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs

Molecular Therapy

Volumn 10, Issue 2, 2004, Pages 386-398

  Hagstrom, James E ^a   Hegge, Julia ^a   Zhang, Guofeng ^b   Noble, Mark ^a   Budker, Vladimir ^b   Lewis, David L ^a   Herweijer, Hans ^a   Wolff, Jon A ^b  

^a Mirus Bio Corporation   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Intravascular; Intravenous; Muscle gene therapy; Muscular dystrophy; Nonviral; siRNA

Indexed keywords

NAKED DNA; NUCLEIC ACID; PLASMID DNA; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SAFETY; DRUG TOXICITY; EXTRAVASATION; FEMALE; GENE EXPRESSION; LEG MUSCLE; MALE; MAMMAL; MOUSE; MUSCLE CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; RAT; SKELETAL MUSCLE; TOURNIQUET; TRANSGENE;

ANIMALS; BETA-GALACTOSIDASE; CREATINE KINASE; DNA; DOGS; EXTREMITIES; GENE THERAPY; GENE TRANSFER TECHNIQUES; HAPLORHINI; INJECTIONS, INTRAVENOUS; MUSCLE, SKELETAL; PLASMIDS; RATS; RNA, SMALL INTERFERING; VEINS;

ANIMALIA; MAMMALIA;

EID: 4344715026     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.05.004     Document Type: Article

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