메뉴 건너뛰기




Volumn 24, Issue 8, 2003, Pages 434-439

What is the relevance of bioinformatics to pharmacology?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ANTIVIRUS AGENT; BIOLOGICAL MARKER; VACCINE;

EID: 0042160230     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(03)00197-4     Document Type: Review
Times cited : (46)

References (75)
  • 1
    • 0014547638 scopus 로고
    • Computer analysis of protein evolution
    • Dayhoff M.O. Computer analysis of protein evolution. Sci. Am. 221:1969;86-95.
    • (1969) Sci. Am. , vol.221 , pp. 86-95
    • Dayhoff, M.O.1
  • 2
    • 0017815318 scopus 로고
    • A program for teaching bio-informatics
    • Rybak B. A program for teaching bio-informatics. Bioscience Communications. 4:1978;158-159.
    • (1978) Bioscience Communications , vol.4 , pp. 158-159
    • Rybak, B.1
  • 3
    • 0037252704 scopus 로고    scopus 로고
    • The Molecular Biology Database Collection: 2003 update
    • Baxevanis A.D. The Molecular Biology Database Collection: 2003 update. Nucleic Acids Res. 31:2003;1-12.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 1-12
    • Baxevanis, A.D.1
  • 4
    • 0034868592 scopus 로고    scopus 로고
    • What is bioinformatics? A proposed definition and overview of the field
    • Luscombe N.M., et al. What is bioinformatics? A proposed definition and overview of the field. Methods Inf. Med. 40:2001;346-358.
    • (2001) Methods Inf. Med. , vol.40 , pp. 346-358
    • Luscombe, N.M.1
  • 6
    • 0036849112 scopus 로고    scopus 로고
    • Yellow pages to the transcriptome
    • Scheel J., et al. Yellow pages to the transcriptome. Pharmacogenomics. 3:2002;791-807.
    • (2002) Pharmacogenomics , vol.3 , pp. 791-807
    • Scheel, J.1
  • 7
    • 0036899286 scopus 로고    scopus 로고
    • From patterns to pathways: Gene expression data analysis comes of age
    • Slonim D.K. From patterns to pathways: gene expression data analysis comes of age. Nat. Genet. 32:2002;502-508.
    • (2002) Nat. Genet. , vol.32 , pp. 502-508
    • Slonim, D.K.1
  • 8
    • 0036215449 scopus 로고    scopus 로고
    • Proteomics and its impact upon biomedical science
    • Marshall T., Williams K.M. Proteomics and its impact upon biomedical science. Br. J. Biomed. Sci. 59:2002;47-64.
    • (2002) Br. J. Biomed. Sci. , vol.59 , pp. 47-64
    • Marshall, T.1    Williams, K.M.2
  • 9
    • 0036667384 scopus 로고    scopus 로고
    • 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer
    • Weinstein J.N. 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer. Curr. Opin. Pharmacol. 2:2002;361-365.
    • (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 361-365
    • Weinstein, J.N.1
  • 10
    • 0034077507 scopus 로고    scopus 로고
    • Sequencing the entire genomes of free-living organisms: The foundation of pharmacology in the new millennium
    • Broder S., Venter J.C. Sequencing the entire genomes of free-living organisms: the foundation of pharmacology in the new millennium. Annu. Rev. Pharmacol. Toxicol. 40:2000;97-132.
    • (2000) Annu. Rev. Pharmacol. Toxicol. , vol.40 , pp. 97-132
    • Broder, S.1    Venter, J.C.2
  • 12
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs - will they model the next 100?
    • Zambrowicz B.P., Sands A.T. Knockouts model the 100 best-selling drugs - will they model the next 100? Nat. Rev. Drug Discov. 2:2003;38-51.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2
  • 13
    • 0036755003 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction
    • Corbin J.D., et al. Phosphodiesterase type 5 as a pharmacologic target in erectile dysfunction. Urology. 60:2002;4-11.
    • (2002) Urology , vol.60 , pp. 4-11
    • Corbin, J.D.1
  • 14
    • 4243926785 scopus 로고    scopus 로고
    • Imatinib and chronic myeloid leukemia: Validating the promise of molecularly targeted therapy
    • Druker B.J. Imatinib and chronic myeloid leukemia: validating the promise of molecularly targeted therapy. Eur. J. Cancer. 38:2002;S70-S76.
    • (2002) Eur. J. Cancer , vol.38
    • Druker, B.J.1
  • 15
    • 0035415861 scopus 로고    scopus 로고
    • From symptomatic treatments to causative therapy?
    • Whittaker P.A. From symptomatic treatments to causative therapy? Curr. Opin. Chem. Biol. 5:2001;352-359.
    • (2001) Curr. Opin. Chem. Biol. , vol.5 , pp. 352-359
    • Whittaker, P.A.1
  • 16
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: A historical perspective
    • Drews J. Drug discovery: a historical perspective. Science. 287:2000;1960-1964.
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.1
  • 17
    • 0036791447 scopus 로고    scopus 로고
    • Receptor classification: Post genome
    • Foord S.M. Receptor classification: post genome. Curr. Opin. Pharmacol. 2:2002;561-566.
    • (2002) Curr. Opin. Pharmacol. , vol.2 , pp. 561-566
    • Foord, S.M.1
  • 18
    • 0035827339 scopus 로고    scopus 로고
    • A genomic perspective on human proteases
    • Southan C. A genomic perspective on human proteases. FEBS Lett. 498:2001;214-218.
    • (2001) FEBS Lett. , vol.498 , pp. 214-218
    • Southan, C.1
  • 19
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • Manning G., et al. The protein kinase complement of the human genome. Science. 298:2002;1912-1934.
    • (2002) Science , vol.298 , pp. 1912-1934
    • Manning, G.1
  • 20
    • 0003293442 scopus 로고    scopus 로고
    • Molecular identification of high and low affinity receptors for nicotinic acid
    • Wise A., et al. Molecular identification of high and low affinity receptors for nicotinic acid. J. Biol. Chem. 278:2003;9869-9874.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9869-9874
    • Wise, A.1
  • 21
    • 0035993441 scopus 로고    scopus 로고
    • Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach
    • Chalker A.F., Lunsford R.D. Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach. Pharmacol. Ther. 95:2002;1-20.
    • (2002) Pharmacol. Ther. , vol.95 , pp. 1-20
    • Chalker, A.F.1    Lunsford, R.D.2
  • 22
    • 0036018926 scopus 로고    scopus 로고
    • Hepatitis C virus proteins as targets for drug development: The role of bioinformatics and modelling
    • Lahm A., et al. Hepatitis C virus proteins as targets for drug development: the role of bioinformatics and modelling. Curr. Drug Targets. 3:2002;281-296.
    • (2002) Curr. Drug Targets , vol.3 , pp. 281-296
    • Lahm, A.1
  • 23
    • 0035989334 scopus 로고    scopus 로고
    • Immuno-informatics: Mining genomes for vaccine components
    • De Groot A.S., et al. Immuno-informatics: mining genomes for vaccine components. Immunol. Cell Biol. 80:2002;255-269.
    • (2002) Immunol. Cell Biol. , vol.80 , pp. 255-269
    • De Groot, A.S.1
  • 24
    • 0037034044 scopus 로고    scopus 로고
    • Plasmodium, human and Anopheles genomics and malaria
    • Hoffman S.L., et al. Plasmodium, human and Anopheles genomics and malaria. Nature. 415:2002;702-709.
    • (2002) Nature , vol.415 , pp. 702-709
    • Hoffman, S.L.1
  • 25
    • 0035206101 scopus 로고    scopus 로고
    • Genome analysis with gene-indexing databases
    • Yuan J., et al. Genome analysis with gene-indexing databases. Pharmacol. Ther. 91:2001;115-132.
    • (2001) Pharmacol. Ther. , vol.91 , pp. 115-132
    • Yuan, J.1
  • 26
    • 0035864810 scopus 로고    scopus 로고
    • Whole-body gene expression by data mining
    • Pires M.R., et al. Whole-body gene expression by data mining. Genomics. 72:2001;34-42.
    • (2001) Genomics , vol.72 , pp. 34-42
    • Pires, M.R.1
  • 27
    • 0036342301 scopus 로고    scopus 로고
    • Bioinformatics-based discovery of a novel factor with apparent specificity to colon cancer
    • De Young M.P., et al. Bioinformatics-based discovery of a novel factor with apparent specificity to colon cancer. In Vivo. 16:2002;239-248.
    • (2002) In Vivo , vol.16 , pp. 239-248
    • De Young, M.P.1
  • 28
    • 0035970294 scopus 로고    scopus 로고
    • An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors
    • Wittenberger T., et al. An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J. Mol. Biol. 307:2001;799-813.
    • (2001) J. Mol. Biol. , vol.307 , pp. 799-813
    • Wittenberger, T.1
  • 29
    • 0037458085 scopus 로고    scopus 로고
    • Microarrays: The use of oligonucleotides and cDNA for the analysis of gene expression
    • Barrett J.C., Kawasaki E.S. Microarrays: the use of oligonucleotides and cDNA for the analysis of gene expression. Drug Discov. Today. 8:2003;134-141.
    • (2003) Drug Discov. Today , vol.8 , pp. 134-141
    • Barrett, J.C.1    Kawasaki, E.S.2
  • 30
    • 0036216372 scopus 로고    scopus 로고
    • Application of gene expression profiling to cardiovascular disease
    • Henriksen P.A., Kotelevtsev Y. Application of gene expression profiling to cardiovascular disease. Cardiovasc. Res. 54:2002;16-24.
    • (2002) Cardiovasc. Res. , vol.54 , pp. 16-24
    • Henriksen, P.A.1    Kotelevtsev, Y.2
  • 31
    • 0036211235 scopus 로고    scopus 로고
    • Functional genomics approaches to understanding brain disorders
    • Shilling P.D., Kelsoe J.R. Functional genomics approaches to understanding brain disorders. Pharmacogenomics. 3:2002;31-45.
    • (2002) Pharmacogenomics , vol.3 , pp. 31-45
    • Shilling, P.D.1    Kelsoe, J.R.2
  • 32
    • 0036884167 scopus 로고    scopus 로고
    • The use and analysis of microarray data
    • Butte A. The use and analysis of microarray data. Nat. Rev. Drug Discov. 1:2002;951-960.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 951-960
    • Butte, A.1
  • 33
    • 0037107935 scopus 로고    scopus 로고
    • From microarrays to networks: Mining expression time series
    • Dewey T.G. From microarrays to networks: mining expression time series. Drug Discov. Today. 7:2002;S170-S175.
    • (2002) Drug Discov. Today , vol.7
    • Dewey, T.G.1
  • 34
    • 0037871684 scopus 로고    scopus 로고
    • Genes for asthma: Much ado about nothing?
    • Whittaker P.A. Genes for asthma: much ado about nothing? Curr. Opin. Pharmacol. 3:2003;212-219.
    • (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 212-219
    • Whittaker, P.A.1
  • 35
    • 0035408587 scopus 로고    scopus 로고
    • Genome annotation: From sequence to biology
    • Stein L. Genome annotation: from sequence to biology. Nat. Rev. Genet. 2:2001;493-503.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 493-503
    • Stein, L.1
  • 36
    • 0035874906 scopus 로고    scopus 로고
    • From genome to function
    • Thornton J.M. From genome to function. Science. 292:2001;2095-2097.
    • (2001) Science , vol.292 , pp. 2095-2097
    • Thornton, J.M.1
  • 37
    • 0035279936 scopus 로고    scopus 로고
    • Towards an understanding of complex protein networks
    • Tucker C.L., et al. Towards an understanding of complex protein networks. Trends Cell Biol. 11:2001;102-106.
    • (2001) Trends Cell Biol. , vol.11 , pp. 102-106
    • Tucker, C.L.1
  • 38
    • 0035369531 scopus 로고    scopus 로고
    • Protein-protein interaction maps: A lead towards cellular functions
    • Legrain P., et al. Protein-protein interaction maps: a lead towards cellular functions. Trends Genet. 17:2001;346-352.
    • (2001) Trends Genet. , vol.17 , pp. 346-352
    • Legrain, P.1
  • 39
    • 0036377939 scopus 로고    scopus 로고
    • Bioinformatics: From genome to drug targets
    • Dahl S.G., et al. Bioinformatics: from genome to drug targets. Ann. Med. 34:2002;306-312.
    • (2002) Ann. Med. , vol.34 , pp. 306-312
    • Dahl, S.G.1
  • 40
    • 0037119336 scopus 로고    scopus 로고
    • From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries
    • Breinbauer R., et al. From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries. Angew. Chem. Int. Ed. Engl. 41:2002;2879-2890.
    • (2002) Angew. Chem. Int. Ed. Engl. , vol.41 , pp. 2879-2890
    • Breinbauer, R.1
  • 41
    • 0037059061 scopus 로고    scopus 로고
    • Combining computational and experimental screening for rapid optimization of protein properties
    • Hayes R.J., et al. Combining computational and experimental screening for rapid optimization of protein properties. Proc. Natl. Acad. Sci. U. S. A. 99:2002;15926-15931.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 15926-15931
    • Hayes, R.J.1
  • 42
    • 0036051992 scopus 로고    scopus 로고
    • High-throughput crystallography for lead discovery in drug design
    • Blundell T.L., et al. High-throughput crystallography for lead discovery in drug design. Nat. Rev. Drug Discov. 1:2002;45-54.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 45-54
    • Blundell, T.L.1
  • 43
    • 0036628560 scopus 로고    scopus 로고
    • An ontology for pharmaceutical ligands and its application for in silico screening and library design
    • Schuffenhauer A., et al. An ontology for pharmaceutical ligands and its application for in silico screening and library design. J. Chem. Inf. Comput. Sci. 42:2002;947-955.
    • (2002) J. Chem. Inf. Comput. Sci. , vol.42 , pp. 947-955
    • Schuffenhauer, A.1
  • 44
    • 0036194512 scopus 로고    scopus 로고
    • Chemical genomics: A systematic approach in biological research and drug discovery
    • Zheng X.F., Chan T.F. Chemical genomics: a systematic approach in biological research and drug discovery. Curr. Issues Mol. Biol. 4:2002;33-43.
    • (2002) Curr. Issues Mol. Biol. , vol.4 , pp. 33-43
    • Zheng, X.F.1    Chan, T.F.2
  • 45
    • 0036367324 scopus 로고    scopus 로고
    • Pharmacogenomic-guided drug development: Regulatory perspective
    • Lesko L.J., Woodcock J. Pharmacogenomic-guided drug development: regulatory perspective. Pharmacogenomics J. 2:2002;20-24.
    • (2002) Pharmacogenomics J. , vol.2 , pp. 20-24
    • Lesko, L.J.1    Woodcock, J.2
  • 46
    • 0036900945 scopus 로고    scopus 로고
    • Medical applications of microarray technologies: A regulatory science perspective
    • Petricoin E.F. III, et al. Medical applications of microarray technologies: a regulatory science perspective. Nat. Genet. 32:2002;474-479.
    • (2002) Nat. Genet. , vol.32 , pp. 474-479
    • Petricoin E.F. III1
  • 47
    • 0036173893 scopus 로고    scopus 로고
    • Challenges for biomedical informatics and pharmacogenomics
    • Altman R.B., Klein T.E. Challenges for biomedical informatics and pharmacogenomics. Annu. Rev. Pharmacol. Toxicol. 42:2002;113-133.
    • (2002) Annu. Rev. Pharmacol. Toxicol. , vol.42 , pp. 113-133
    • Altman, R.B.1    Klein, T.E.2
  • 48
    • 0036204734 scopus 로고    scopus 로고
    • In silico approaches to mechanistic and predictive toxicology: An introduction to bioinformatics for toxicologists
    • Fielden M.R., et al. In silico approaches to mechanistic and predictive toxicology: an introduction to bioinformatics for toxicologists. Crit. Rev. Toxicol. 32:2002;67-112.
    • (2002) Crit. Rev. Toxicol. , vol.32 , pp. 67-112
    • Fielden, M.R.1
  • 49
    • 0035037328 scopus 로고    scopus 로고
    • Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies
    • Lesko L.J., Atkinson A.J. Jr. Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies. Annu. Rev. Pharmacol. Toxicol. 41:2001;347-366.
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 347-366
    • Lesko, L.J.1    Atkinson A.J., Jr.2
  • 50
    • 0036677602 scopus 로고    scopus 로고
    • Reinventing pharma: The theranostic revolution
    • (
    • Funkhouser J. Reinventing pharma: the theranostic revolution. Current Drug Discovery. 2002;17-19. ( http://www.currentdrugdiscovery.com/2002/august.html ).
    • (2002) Current Drug Discovery , pp. 17-19
    • Funkhouser, J.1
  • 51
    • 0036850750 scopus 로고    scopus 로고
    • Rapid molecular theranostics in infectious diseases
    • Picard F.J., Bergeron M.G. Rapid molecular theranostics in infectious diseases. Drug Discov. Today. 7:2002;1092-1101.
    • (2002) Drug Discov. Today , vol.7 , pp. 1092-1101
    • Picard, F.J.1    Bergeron, M.G.2
  • 52
    • 0037252179 scopus 로고    scopus 로고
    • The identification of clinically relevant markers and therapeutic targets
    • Nicolette C.A., Miller G.A. The identification of clinically relevant markers and therapeutic targets. Drug Discov. Today. 8:2003;31-38.
    • (2003) Drug Discov. Today , vol.8 , pp. 31-38
    • Nicolette, C.A.1    Miller, G.A.2
  • 53
    • 0037271069 scopus 로고    scopus 로고
    • The future of clinical cancer management: One tumor, one chip
    • Yeatman T.J. The future of clinical cancer management: one tumor, one chip. Am. Surg. 69:2003;41-44.
    • (2003) Am. Surg. , vol.69 , pp. 41-44
    • Yeatman, T.J.1
  • 54
    • 0036718796 scopus 로고    scopus 로고
    • Clinical proteomics: Translating benchside promise into bedside reality
    • Petricoin E.F., et al. Clinical proteomics: translating benchside promise into bedside reality. Nat. Rev. Drug Discov. 1:2002;683-695.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 683-695
    • Petricoin, E.F.1
  • 55
    • 0036320438 scopus 로고    scopus 로고
    • Proteomics for cancer biomarker discovery
    • Srinivas P.R., et al. Proteomics for cancer biomarker discovery. Clin. Chem. 48:2002;1160-1169.
    • (2002) Clin. Chem. , vol.48 , pp. 1160-1169
    • Srinivas, P.R.1
  • 56
    • 0035369825 scopus 로고    scopus 로고
    • Genetic susceptibility to adverse drug reactions
    • Pirmohamed M., Park B.K. Genetic susceptibility to adverse drug reactions. Trends Pharmacol. Sci. 22:2001;298-305.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 298-305
    • Pirmohamed, M.1    Park, B.K.2
  • 57
    • 0035252388 scopus 로고    scopus 로고
    • Pharmacogenomics of psychiatric disorders
    • Pickar D., Rubinow K. Pharmacogenomics of psychiatric disorders. Trends Pharmacol. Sci. 22:2001;75-83.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 75-83
    • Pickar, D.1    Rubinow, K.2
  • 58
    • 0036629712 scopus 로고    scopus 로고
    • Genotypic drug resistance interpretation systems-the cutting edge of antiretroviral therapy
    • Schmidt B., et al. Genotypic drug resistance interpretation systems-the cutting edge of antiretroviral therapy. AIDS Rev. 4:2002;148-156.
    • (2002) AIDS Rev. , vol.4 , pp. 148-156
    • Schmidt, B.1
  • 59
    • 0036050211 scopus 로고    scopus 로고
    • Pharmacogenomic analysis: Correlating molecular substructure classes with microarray gene expression data
    • Blower P.E., et al. Pharmacogenomic analysis: correlating molecular substructure classes with microarray gene expression data. Pharmacogenomics J. 2:2002;259-271.
    • (2002) Pharmacogenomics J. , vol.2 , pp. 259-271
    • Blower, P.E.1
  • 60
    • 0036174441 scopus 로고    scopus 로고
    • Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae
    • Emerson L.R., et al. Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 46:2002;787-796.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 787-796
    • Emerson, L.R.1
  • 61
    • 0036720460 scopus 로고    scopus 로고
    • Progress toward virtual screening for drug side effects
    • Rockey W.M., Elcock A.H. Progress toward virtual screening for drug side effects. Proteins. 48:2002;664-671.
    • (2002) Proteins , vol.48 , pp. 664-671
    • Rockey, W.M.1    Elcock, A.H.2
  • 62
    • 0037184855 scopus 로고    scopus 로고
    • Genomic interrogation of mechanism(s) underlying cellular responses to toxicants
    • Amin R.P., et al. Genomic interrogation of mechanism(s) underlying cellular responses to toxicants. Toxicology. 181-182:2002;555-563.
    • (2002) Toxicology , vol.181-182 , pp. 555-563
    • Amin, R.P.1
  • 63
    • 0036043671 scopus 로고    scopus 로고
    • Toxicogenomics and drug discovery: Will new technologies help us produce better drugs?
    • Ulrich R., Friend S.H. Toxicogenomics and drug discovery: will new technologies help us produce better drugs? Nat. Rev. Drug Discov. 1:2002;84-88.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 84-88
    • Ulrich, R.1    Friend, S.H.2
  • 64
    • 0036649486 scopus 로고    scopus 로고
    • The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis
    • Kennedy S. The role of proteomics in toxicology: identification of biomarkers of toxicity by protein expression analysis. Biomarkers. 7:2002;269-290.
    • (2002) Biomarkers , vol.7 , pp. 269-290
    • Kennedy, S.1
  • 65
    • 0035190398 scopus 로고    scopus 로고
    • Discovery in toxicology: Mediation by gene expression array technology
    • Hamadeh H.K., et al. Discovery in toxicology: mediation by gene expression array technology. J. Biochem. Mol. Toxicol. 15:2001;231-242.
    • (2001) J. Biochem. Mol. Toxicol. , vol.15 , pp. 231-242
    • Hamadeh, H.K.1
  • 66
    • 0036783335 scopus 로고    scopus 로고
    • Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes
    • Rushmore T.H., Kong A.N. Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. Curr. Drug Metab. 3:2002;481-490.
    • (2002) Curr. Drug Metab. , vol.3 , pp. 481-490
    • Rushmore, T.H.1    Kong, A.N.2
  • 67
    • 0036463681 scopus 로고    scopus 로고
    • Metabonomics: A platform for studying drug toxicity and gene function
    • Nicholson J.K., et al. Metabonomics: a platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1:2002;153-161.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 153-161
    • Nicholson, J.K.1
  • 68
    • 0037192320 scopus 로고    scopus 로고
    • Toxicology and genetic toxicology in the new era of 'toxicogenomics': Impact of '-omics' technologies
    • Aardema M.J., MacGregor J.T. Toxicology and genetic toxicology in the new era of 'toxicogenomics': impact of '-omics' technologies. Mutat. Res. 499:2002;13-25.
    • (2002) Mutat. Res. , vol.499 , pp. 13-25
    • Aardema, M.J.1    MacGregor, J.T.2
  • 69
    • 0037444362 scopus 로고    scopus 로고
    • Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project
    • Lindon J.C., et al. Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project. Toxicol. Appl. Pharmacol. 187:2003;137-146.
    • (2003) Toxicol. Appl. Pharmacol. , vol.187 , pp. 137-146
    • Lindon, J.C.1
  • 70
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano H. Computational systems biology. Nature. 420:2002;206-210.
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 71
    • 0037590604 scopus 로고    scopus 로고
    • Overview of the Alliance for Cellular Signaling
    • Gilman A.G., et al. Overview of the Alliance for Cellular Signaling. Nature. 420:2002;703-706.
    • (2002) Nature , vol.420 , pp. 703-706
    • Gilman, A.G.1
  • 72
    • 0037069697 scopus 로고    scopus 로고
    • The Molecule Pages database
    • Li J., et al. The Molecule Pages database. Nature. 420:2002;716-717.
    • (2002) Nature , vol.420 , pp. 716-717
    • Li, J.1
  • 73
    • 0036468236 scopus 로고    scopus 로고
    • The TGF-beta-Smad network: Introducing bioinformatic tools
    • Kloos D.U., et al. The TGF-beta-Smad network: introducing bioinformatic tools. Trends Genet. 18:2002;96-103.
    • (2002) Trends Genet. , vol.18 , pp. 96-103
    • Kloos, D.U.1
  • 74
    • 0037323878 scopus 로고    scopus 로고
    • The future: Putting Humpty-Dumpty together again
    • Noble D. The future: putting Humpty-Dumpty together again. Biochem. Soc. Trans. 31:2003;156-158.
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 156-158
    • Noble, D.1
  • 75
    • 0037204540 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetic simulation modelling
    • Grass G.M., Sinko P.J. Physiologically-based pharmacokinetic simulation modelling. Adv. Drug Deliv. Rev. 54:2002;433-451.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 433-451
    • Grass, G.M.1    Sinko, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.