-
1
-
-
0037470952
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum, L. et al. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299, 2039-2045 (2003).
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
-
2
-
-
0037448540
-
Systematic functional analysis of the Caenorhabilitis elegans genome using RNAi
-
Kamath, R. S. et al. Systematic functional analysis of the Caenorhabilitis elegans genome using RNAi. Nature 421, 231-237 (2003).
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
-
3
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabilitis elegans fat regulatory genes
-
Ashrafi, K. et al. Genome-wide RNAi analysis of Caenorhabilitis elegans fat regulatory genes. Nature 421, 268-272 (2003).
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
-
4
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T. R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
5
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J. & Conklin, D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
6
-
-
0037062951
-
RNA interference
-
Hannon, G. J. RNA interference. Nature 418, 244-251 (2002).
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
7
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S. M. et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498 (2001).
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
-
8
-
-
0035487104
-
The ink4a/ARF network in tumour suppression
-
Sherr, C. J. The ink4a/ARF network in tumour suppression. Nature Rev. Mol. Cell Biol. 2, 731-737 (2001).
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 731-737
-
-
Sherr, C.J.1
-
9
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp, T., Bernards, R. & Agami, R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2, 243-247 (2002).
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.1
Bernards, R.2
Agami, R.3
-
10
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
-
Brummelkamp, T. R., Nijman, S. M., Dirac, A. M. & Bernards, R. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB. Nature 424, 797-801 (2003).
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.2
Dirac, A.M.3
Bernards, R.4
-
11
-
-
0038121109
-
Specificity of short interfering RNA determined through gene expression signatures
-
Semizarov, D. et al. Specificity of short interfering RNA determined through gene expression signatures. Proc. Natl Acad. Sci. USA 100, 6347-6352 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6347-6352
-
-
Semizarov, D.1
-
12
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson, A. L. et al. Expression profiling reveals off-target gene regulation by RNAi. Nature Biotechnol. 21, 635-637 (2003).
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
-
13
-
-
0030728468
-
Tumor suppression at the mouse INK 4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo, T. et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91, 649-659 (1997).
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
-
14
-
-
0033552595
-
Regulation of p53 in response to DNA damage
-
Lakin, N. D. & Jackson, S. P. Regulation of p53 in response to DNA damage. Oncogene 18, 7644-7655 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 7644-7655
-
-
Lakin, N.D.1
Jackson, S.P.2
-
15
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W. S. et al. WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825 (1993).
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
-
16
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas, J. et al. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377, 552-557 (1995).
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
-
17
-
-
0028849274
-
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman, T., Kinzler, K. W. & Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55, 5187-5190 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
18
-
-
0030609861
-
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
-
Brown, J. P., Wei, W. & Sedivy, J. M. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277, 831-834 (1997).
-
(1997)
Science
, vol.277
, pp. 831-834
-
-
Brown, J.P.1
Wei, W.2
Sedivy, J.M.3
-
19
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita, T. & Reed, J. C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299 (1995).
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
20
-
-
0027459198
-
mdm2 expression is induced by wild type p53 activity
-
Barak, Y., Juven, T., Haffner, R. & Oren, M. mdm2 expression is induced by wild type p53 activity. EMBO J. 12, 461-468 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
21
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H., Jones, S. N. & Vousden, K. H. Regulation of p53 stability by Mdm2. Nature 387, 299-303 (1997).
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
22
-
-
0142259345
-
New tools for functional mammalian cancer genetics
-
Brummelkamp, T. R. & Bernards, R. New tools for functional mammalian cancer genetics. Nature Rev. Cancer 3, 781-789 (2003).
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 781-789
-
-
Brummelkamp, T.R.1
Bernards, R.2
-
23
-
-
0029804246
-
Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy
-
Shoemaker, D. D., Lashkari, D. A., Morris, D., Mittmann, M. & Davis, R. W. Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy. Nature Genet. 14, 450-456 (1996).
-
(1996)
Nature Genet.
, vol.14
, pp. 450-456
-
-
Shoemaker, D.D.1
Lashkari, D.A.2
Morris, D.3
Mittmann, M.4
Davis, R.W.5
-
24
-
-
0037155231
-
TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p 19ARF and inhibits senescence
-
Brummelkamp, T. R. et al. TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence. J. Biol. Chem. 277, 6567-6572 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6567-6572
-
-
Brummelkamp, T.R.1
-
25
-
-
0032568321
-
Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells
-
Kanda, T., Sullivan, K. F. & Wahl, G. M. Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Curr. Biol. 8, 377-385 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 377-385
-
-
Kanda, T.1
Sullivan, K.F.2
Wahl, G.M.3
-
26
-
-
0032696590
-
HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor
-
Wang, A. H. et al. HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor. Mol. Cell. Biol. 19, 7816-7827 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7816-7827
-
-
Wang, A.H.1
-
27
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz, D. S. et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199-208 (2003).
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
-
28
-
-
12444316158
-
Platinum(II)-based coordination compounds as nucleic acid labeling reagents: Synthesis, reactivity, and applications in hybridization assays
-
Heetebrij, R. J. et al. Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays. Chembiochem 4, 573-583 (2003).
-
(2003)
Chembiochem
, vol.4
, pp. 573-583
-
-
Heetebrij, R.J.1
-
29
-
-
0034703869
-
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
-
Trettel, F. et al. Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum. Mol. Genet. 9, 2799-2809 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2799-2809
-
-
Trettel, F.1
-
30
-
-
0037686707
-
Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53
-
Dirac, A. M. & Bernards, R. Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. J. Biol. Chem. 278, 11731-11734 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11731-11734
-
-
Dirac, A.M.1
Bernards, R.2
|