siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells

Oncogene

Volumn 22, Issue 38, 2003, Pages 5938-5945

  Butz, Karin ^a   Ristriani, Tutik ^a   Hengstermann, Arnd ^b   Denk, Claudia ^a   Scheffner, Martin ^b   Hoppe Seyler, Felix ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Apoptosis; Human papillomavirus; RNA interference; Tumour therapy; Tumour virus

Indexed keywords

RNA;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL TRANSFORMATION; CONTROLLED STUDY; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN TARGETING; VIRUS ONCOGENE; VIRUS ONCOGENE E6; WART VIRUS;

APOPTOSIS; DNA-BINDING PROTEINS; GENE THERAPY; HELA CELLS; HUMANS; ONCOGENE PROTEINS, VIRAL; RETINOBLASTOMA PROTEIN; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY; TUMOR SUPPRESSOR PROTEIN P53;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPES; PAPILLOMAVIRUS; PAPOVAVIRIDAE; RNA VIRUSES;

EID: 0141730323     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206894     Document Type: Article

References (46)

1. Agami R. (2002). Curr. Opin. Chem. Biol., 6, 829-834.
2. Brummelkamp TR, Bernards R and Agami R. (2002a). Cancer Cell, 2, 243-247.
3. Brummelkamp TR, Bernards R and Agami R. (2002b). Science, 296, 550-553.
4. Butz K, Denk C, Ullmann A, Scheffner M and Hoppe-Seyler F. (2000). Proc. Natl. Acad. Sci. USA, 97, 6693-6697.
5. Butz K, Geisen C, Ullmann A, Zentgraf H and Hoppe-Seyler F. (1998). Oncogene, 17, 781-787.
6. Butz K, Shahabeddin L, Geisen C, Spitkovsky D, Ullmann A and Hoppe-Seyler F. (1995). Oncogene, 10, 927-936.
7. Chen C and Okayama H. (1987). Mol. Cell. Biol., 7, 2745-2752.
8. Chomczynski P and Sacchi N. (1987). Anal. Biochem., 162, 156-159.
9. Cole ST and Danos O. (1987). J. Mol. Biol., 193, 599-608.
10. Elbashir SM, Harboth J, Lendeckel W, Yalcin A, Weber K and Tuschl T. (2001). Nature, 411, 494-498.
11. Elbashir SM, Harboth J, Weber K and Tuschl T. (2002). Methods, 26, 199-213.
12. El-Deiry WS, Tokino T, Velculescu VE, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
13. Evan GI and Vousden KH. (2001). Nature, 411, 342-348.
14. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE and Mello CC. (1998). Nature, 391, 806-811.
15. Fulda S, Wick W, Weller M and Debatin M. (2002). Nat. Med., 8, 808-815.
16. Funk WD, Pak DT, Karas RH, Wright WE and Shay JW. (1992). Mol. Cell. Biol., 12, 2866-2871.
17. Goodwin EC and DiMaio D. (2000). Proc. Natl. Acad. Sci. USA, 97, 12513-12518.
18. Hoppe-Seyler F and Butz K. (1999). Anticancer Res., 19, 4747-4758.
19. Igney FH and Krammer PH. (2002). Nat. Rev. Cancer, 2, 277-288.
20. Jaque J-M, Triques K and Stevenson M. (2002). Nature, 418, 435-438.
21. Jiang M and Milner J. (2002). Oncogene, 21, 6041-6048.
22. Lee NS, Dohjima T, Bauer G, Li H, Li M-J, Ehsani A, Salvaterra P and Rossi J. (2002). Nat. Biotechnol., 19, 500-505.
23. Mantovani F and Banks L. (2001). Oncogene, 20, 7874-7887.
24. Mittnacht S. (1998). Curr. Opin. Genet. Dev., 8, 21-27.
25. Morris MC, Chaloin L, Heitz F and Divita G. (2000). Curr. Opin. Biotechnol., 11, 461-466.
26. Münger K, Basile JR, Duensing S, Eichten A, Gonzalez SL, Grace M and Zacny VL. (2001). Oncogene, 20, 7888-7898.
27. Nicholson DW. (2000). Nature, 407, 810-816.
28. Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee S-K, Collman RG, Lieberman J, Shankar P and Sharp PA. (2002). Nat. Med., 8, 681-686.
29. Paddison PJ and Hannon GJ. (2002). Cancer Cell, 2, 17-23.
30. Pan H and Griep AE. (1994). Genes Dev., 9, 2157-2169.
31. Parkin DM, Bray FI and Devesa SS. (2001). Eur. J. Cancer, 37, S4-S66.
32. Reed JC. (2001). Trends Mol. Med., 7, 314-319.
33. Rittner K, Benavente A, Bompard-Sorlet A, Heitz F, Divita G, Brasseur R and Jacobs E. (2002). Mol. Ther., 5, 104-114.
34. Rothbard JB, Garlington S, Lin Q, Kirschberg T, Kreider E, McGrane PL, Wender P and Khavari PA. (2000). Nat. Med., 11, 1253-1257.
35. Salvesen GS and Duckett CS. (2002). Nat. Rev. Mol. Cell. Biol., 3, 401-410.
36. Scheffner M, Werness BA, Huibregtse JM, Levine AJ and Howley PM. (1990). Cell, 63, 1129-1136.
37. Schneider-Gaedicke A and Schwarz E. (1986). EMBO J., 5, 2285-2292.
38. Sedman SA, Barbosa MS, Vass WC, Hubbert NL, Haas JA, Lowy DR and Schiller JT. (1991). J. Virol., 65, 4860-4866.
39. Smotkin D, Prokoph H and Wettstein FO. (1989). J. Virol., 63, 1441-1447.
40. Southern PJ and Berg P. (1982). J. Mol. Appl. Genet., 1, 327-341.
41. Thomas M and Banks L. (1998). Oncogene, 17, 2943-2954.
42. Thomas M and Banks L. (1999). Oncogene, 18, 7690-7700.
43. Venturini F, Braspenning J, Homann M, Gissmann L and Sczakiel G. (1999). Nucleic Acids Res., 27, 1585-1592.
44. von Knebel Doeberitz M, Oltersdorf T, Schwarz E and Gissmann L. (1988). Cancer Res., 48, 3780-3786.
45. Wells SI, Francis DA, Karpova AY, Dowhanick JJ, Benson JD and Howley PM. (2000). EMBO J., 19, 5762-5771.
46. Zur Hausen H. (2002). Nat. Rev. Cancer, 2, 342-350.