Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 49, 2004, Pages 17270-17275

  Thakker, Deepak R ^a   Natt, Francois ^a   Hüsken, Dieter ^a   Maier, Rainer ^a   Müller, Matthias ^a   Van Der Putten, Herman ^a   Hoyer, Daniel ^a   Cryan, John F ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Dopamine transporter; EGFP; in vivo; Target validation

Indexed keywords

DOPAMINE TRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN; BRAIN REGION; BRAIN THIRD VENTRICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; LOCOMOTION; MALE; MESENCEPHALON; MOUSE; NEUROCHEMISTRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; STATISTICAL SIGNIFICANCE; TRANSGENE;

ANIMALS; BRAIN; CEREBRAL VENTRICLES; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOWN-REGULATION; GREEN FLUORESCENT PROTEINS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METHODS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

ANIMALIA;

EID: 10344228801     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406214101     Document Type: Article

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