메뉴 건너뛰기




Volumn 36, Issue , 2002, Pages 489-519

The genetics of RNA silencing

Author keywords

Cosuppression; Post Transcriptional Gene Silencing (PTGS); RNA silencing; RNAi; SiRNAs

Indexed keywords

DOUBLE STRANDED RNA; MESSENGER RNA; RNA;

EID: 0036953376     PISSN: 00664197     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genet.36.043002.091619     Document Type: Review
Times cited : (256)

References (128)
  • 1
    • 0005820503 scopus 로고    scopus 로고
    • Depletion of yeast RNase III blocks correct U2 3′ end end formation and results in polyadenylated but functional U2 snRNA
    • Abou Elela S, Ares M Jr. 1998. Depletion of yeast RNase III blocks correct U2 3′ end end formation and results in polyadenylated but functional U2 snRNA. EMBO J. 17:3738-46
    • (1998) EMBO J. , vol.17 , pp. 3738-3746
    • Abou Elela, S.1    Ares M., Jr.2
  • 2
    • 0037123639 scopus 로고    scopus 로고
    • RNA-dependent RNA polymerases, viruses, and RNA silencing
    • Ahlquist P. 2002. RNA-dependent RNA polymerases, viruses, and RNA silencing. Science 296:1270-73
    • (2002) Science , vol.296 , pp. 1270-1273
    • Ahlquist, P.1
  • 3
    • 0032571483 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional plant gene silencing in response to a pathogen
    • Al-Kaff NS, Covey SN, Kreike MM, Page AM, Pinder R, Dale PJ. 1998. Transcriptional and posttranscriptional plant gene silencing in response to a pathogen. Science 279:2113-15
    • (1998) Science , vol.279 , pp. 2113-2115
    • Al-Kaff, N.S.1    Covey, S.N.2    Kreike, M.M.3    Page, A.M.4    Pinder, R.5    Dale, P.J.6
  • 4
    • 0033935425 scopus 로고    scopus 로고
    • Control of developmental timing in Caenorhabditis elegans
    • Ambros V. 2000. Control of developmental timing in Caenorhabditis elegans. Curr. Opin. Genet. Dev. 10:428-33
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 428-433
    • Ambros, V.1
  • 5
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • Ambros V. 2001. MicroRNAs: tiny regulators with great potential. Cell 107:823-26
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 6
    • 0034613277 scopus 로고    scopus 로고
    • A calmodulin-related protein that suppresses posttranscriptional gene silencing in plants
    • Anandalakshmi R, Marathe R, Ge X, Herr JM Jr, Mau C, et al. 2000. A calmodulin-related protein that suppresses posttranscriptional gene silencing in plants. Science 290:142-44
    • (2000) Science , vol.290 , pp. 142-144
    • Anandalakshmi, R.1    Marathe, R.2    Ge, X.3    Herr J.M., Jr.4    Mau, C.5
  • 8
    • 0030927776 scopus 로고    scopus 로고
    • Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA
    • Angell SM, Baulcombe DC. 1997. Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA. EMBO J. 16:3675-84
    • (1997) EMBO J. , vol.16 , pp. 3675-3684
    • Angell, S.M.1    Baulcombe, D.C.2
  • 9
    • 0035838369 scopus 로고    scopus 로고
    • Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline
    • Aravin AA, Naumova NM, Tulin AV, Vagin VV, Rozovsky YM, Gvozdev VA. 2001. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr. Biol. 11:1017-27
    • (2001) Curr. Biol. , vol.11 , pp. 1017-1027
    • Aravin, A.A.1    Naumova, N.M.2    Tulin, A.V.3    Vagin, V.V.4    Rozovsky, Y.M.5    Gvozdev, V.A.6
  • 10
    • 0030267493 scopus 로고    scopus 로고
    • RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants
    • Baulcombe DC. 1996. RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants. Plant Mol. Biol. 32:79-88
    • (1996) Plant Mol. Biol. , vol.32 , pp. 79-88
    • Baulcombe, D.C.1
  • 11
    • 0034634248 scopus 로고    scopus 로고
    • Unwinding RNA silencing
    • Baulcombe DC. 2001. Unwinding RNA silencing. Science 290:1108
    • (2001) Science , vol.290 , pp. 1108
    • Baulcombe, D.C.1
  • 12
    • 0032567413 scopus 로고    scopus 로고
    • Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans)genes
    • Beclin C, Berthome R, Palauqui JC, Tepfer M, Vaucheret H. 1998. Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans)genes. Virology 252:313-17
    • (1998) Virology , vol.252 , pp. 313-317
    • Beclin, C.1    Berthome, R.2    Palauqui, J.C.3    Tepfer, M.4    Vaucheret, H.5
  • 13
    • 0037117416 scopus 로고    scopus 로고
    • A branched pathway for transgene-induced RNA silencing in plants
    • Beclin C, Boutet S, Waterhouse P, Vaucheret H. 2002. A branched pathway for transgene-induced RNA silencing in plants. Curr. Biol. 12:684-88
    • (2002) Curr. Biol. , vol.12 , pp. 684-688
    • Beclin, C.1    Boutet, S.2    Waterhouse, P.3    Vaucheret, H.4
  • 14
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-66
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 16
    • 0032538794 scopus 로고    scopus 로고
    • Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
    • Brigneti G, Voinnet O, Li WX, Ji LH, Ding SW, Baulcombe DC. 1998. Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana. EMBO J. 17:6739-46
    • (1998) EMBO J. , vol.17 , pp. 6739-6746
    • Brigneti, G.1    Voinnet, O.2    Li, W.X.3    Ji, L.H.4    Ding, S.W.5    Baulcombe, D.C.6
  • 17
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-53
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 19
    • 0036205131 scopus 로고    scopus 로고
    • Involvement of small RNAs and role of the qde genes in the gene silencing pathway in Neurospora
    • Catalanotto C, Azzalin G, Macino G, Cogoni C. 2002. Involvement of small RNAs and role of the qde genes in the gene silencing pathway in Neurospora. Genes Dev. 16:790-95
    • (2002) Genes Dev. , vol.16 , pp. 790-795
    • Catalanotto, C.1    Azzalin, G.2    Macino, G.3    Cogoni, C.4
  • 20
    • 0034306266 scopus 로고    scopus 로고
    • Domains in gene silencing and cell differentiation proteins: The novel PAZ domain and redefinition of the Piwi domain
    • Cerutti L, Mian N, Bateman A. 2000. Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain. Trends Biochem. Sci. 25:481-82
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 481-482
    • Cerutti, L.1    Mian, N.2    Bateman, A.3
  • 21
    • 0029934123 scopus 로고    scopus 로고
    • Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
    • Cogoni C, Irelan JT, Schumacher M, Schmidhauser TJ, Selker EU, Macino G. 1996. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBO J. 15:3153-63
    • (1996) EMBO J. , vol.15 , pp. 3153-3163
    • Cogoni, C.1    Irelan, J.T.2    Schumacher, M.3    Schmidhauser, T.J.4    Selker, E.U.5    Macino, G.6
  • 22
    • 0030885595 scopus 로고    scopus 로고
    • Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa
    • Cogoni C, Macino G. 1997. Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa. Proc. Natl. Acad. Sci. USA 94:10233-38
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10233-10238
    • Cogoni, C.1    Macino, G.2
  • 23
    • 0033551328 scopus 로고    scopus 로고
    • Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
    • Cogoni C, Macino G. 1999. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399:166-69
    • (1999) Nature , vol.399 , pp. 166-169
    • Cogoni, C.1    Macino, G.2
  • 24
    • 0033579344 scopus 로고    scopus 로고
    • Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase
    • Cogoni C, Macino G. 1999. Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase. Science 286:2342-44
    • (1999) Science , vol.286 , pp. 2342-2344
    • Cogoni, C.1    Macino, G.2
  • 25
    • 0034103861 scopus 로고    scopus 로고
    • Potato virus X amplicons in Arabidopsis mediate genetic and epigenetic gene silencing
    • Dalmay T, Hamilton A, Mueller E, Baulcombe DC. 2000. Potato virus X amplicons in Arabidopsis mediate genetic and epigenetic gene silencing. Plant Cell 12:369-79
    • (2000) Plant Cell , vol.12 , pp. 369-379
    • Dalmay, T.1    Hamilton, A.2    Mueller, E.3    Baulcombe, D.C.4
  • 26
    • 0034716924 scopus 로고    scopus 로고
    • An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
    • Dalmay T, Hamilton A, Rudd S, Angell S, Baulcombe DC. 2000. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell 101:543-53
    • (2000) Cell , vol.101 , pp. 543-553
    • Dalmay, T.1    Hamilton, A.2    Rudd, S.3    Angell, S.4    Baulcombe, D.C.5
  • 27
    • 0035901497 scopus 로고    scopus 로고
    • SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis
    • Dalmay T, Horsefield R, Braunstein TH, Baulcombe DC. 2001. SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis. EMBO J. 20:2069-78
    • (2001) EMBO J. , vol.20 , pp. 2069-2078
    • Dalmay, T.1    Horsefield, R.2    Braunstein, T.H.3    Baulcombe, D.C.4
  • 30
    • 0035160923 scopus 로고    scopus 로고
    • RNA interference in Trypanosoma brucei: Cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs
    • Djikeng A, Shi H, Tschudi C, Ullu E. 2001. RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs. RNA 7:1522-30
    • (2001) RNA , vol.7 , pp. 1522-1530
    • Djikeng, A.1    Shi, H.2    Tschudi, C.3    Ullu, E.4
  • 31
    • 0034665818 scopus 로고    scopus 로고
    • A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans
    • Domeier ME, Morse DP, Knight SW, Portereiko M, Bass BL, Mango SE. 2000. A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans. Science 289:1928-31
    • (2000) Science , vol.289 , pp. 1928-1931
    • Domeier, M.E.1    Morse, D.P.2    Knight, S.W.3    Portereiko, M.4    Bass, B.L.5    Mango, S.E.6
  • 32
    • 0037007007 scopus 로고    scopus 로고
    • Using RNA interference to identify genes required for RNA interference
    • Dudley NR, Labbe JC, Goldstein B. 2002. Using RNA interference to identify genes required for RNA interference. Proc. Natl. Acad. Sci. USA 99:4191-96
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4191-4196
    • Dudley, N.R.1    Labbe, J.C.2    Goldstein, B.3
  • 33
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-98
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 34
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. 2001. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15:188-200
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 35
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. 2001. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20:6877-88
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 37
    • 0034633770 scopus 로고    scopus 로고
    • AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
    • Fagard M, Boutet S, Morel JB, Bellini C, Vaucheret H. 2000. AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl. Acad. Sci. USA 97:11650-54
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11650-11654
    • Fagard, M.1    Boutet, S.2    Morel, J.B.3    Bellini, C.4    Vaucheret, H.5
  • 38
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-11
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 40
    • 0034676448 scopus 로고    scopus 로고
    • Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
    • Gonczy P, Echeverri G, Oegema K, Coulson A, Jones SJ, et al. 2000. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408:331-36
    • (2000) Nature , vol.408 , pp. 331-336
    • Gonczy, P.1    Echeverri, G.2    Oegema, K.3    Coulson, A.4    Jones, S.J.5
  • 41
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, et al. 2001. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5
  • 42
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • Grishok A, Tabara H, Mello CC. 2000. Genetic requirements for inheritance of RNAi in C. elegans. Science 287:2494-97
    • (2000) Science , vol.287 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.C.3
  • 43
    • 0029024475 scopus 로고
    • par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S, Kemphues KJ. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81:611-20
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 44
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in post-transcriptional gene silencing in plants
    • Hamilton AJ, Baulcombe DC. 1999. A species of small antisense RNA in post-transcriptional gene silencing in plants. Science 286:950-52
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 45
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, Hannon GJ. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404:293-96
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 47
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
    • Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H. 2002. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res. 30:1757-66
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 48
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD. 2001. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293:834-38
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 49
    • 0033385170 scopus 로고    scopus 로고
    • Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems
    • Jacobsen SE, Running MP, Meyerowitz EM. 1999. Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems. Development 126:5231-43
    • (1999) Development , vol.126 , pp. 5231-5243
    • Jacobsen, S.E.1    Running, M.P.2    Meyerowitz, E.M.3
  • 50
    • 0001787262 scopus 로고    scopus 로고
    • Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans
    • Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J. 2000. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2:1-10
    • (2000) Genome Biol. , vol.2 , pp. 1-10
    • Kamath, R.S.1    Martinez-Campos, M.2    Zipperlen, P.3    Fraser, A.G.4    Ahringer, J.5
  • 51
    • 0032514856 scopus 로고    scopus 로고
    • A counterdefensive strategy of plant viruses: Suppression of posttranscriptional gene silencing
    • Kasschau KD, Carrington JC. 1998. A counterdefensive strategy of plant viruses: suppression of posttranscriptional gene silencing. Cell 95:461-70
    • (1998) Cell , vol.95 , pp. 461-470
    • Kasschau, K.D.1    Carrington, J.C.2
  • 52
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. 2001. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15:2654-59
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 53
    • 0032739015 scopus 로고    scopus 로고
    • Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
    • Ketting RF, Haverkamp TH, van Luenen HG, Plasterk RH. 1999. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99:133-41
    • (1999) Cell , vol.99 , pp. 133-141
    • Ketting, R.F.1    Haverkamp, T.H.2    Van Luenen, H.G.3    Plasterk, R.H.4
  • 54
    • 0034673645 scopus 로고    scopus 로고
    • A genetic link between co-suppression and RNA interference in C. elegans
    • Ketting RF, Plasterk RH. 2000. A genetic link between co-suppression and RNA interference in C. elegans. Nature 404:296-98
    • (2000) Nature , vol.404 , pp. 296-298
    • Ketting, R.F.1    Plasterk, R.H.2
  • 55
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • Knight SW, Bass BL. 2001. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293:2269-71
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 57
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. 2001. Identification of novel genes coding for small expressed RNAs. Science 294:853-58
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 58
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau NC, Lim LP, Weinstein EG, Bartel DP. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294:858-62
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 59
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee RC, Ambros V. 2001. An extensive class of small RNAs in Caenorhabditis elegans. Science 294:862-64
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 60
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. 1993. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-54
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 61
    • 0037123630 scopus 로고    scopus 로고
    • Induction and suppression of RNA silencing by an animal virus
    • Li H, Li WX, Ding SW. 2002. Induction and suppression of RNA silencing by an animal virus. Science 296:1319-21
    • (2002) Science , vol.296 , pp. 1319-1321
    • Li, H.1    Li, W.X.2    Ding, S.W.3
  • 62
    • 0033577701 scopus 로고    scopus 로고
    • Strong host resistance targeted against a viral suppressor of the plant gene silencing defence mechanism
    • Li HW, Lucy AP, Guo HS, Li WX, Ji LH, et al. 1999. Strong host resistance targeted against a viral suppressor of the plant gene silencing defence mechanism. EMBO J. 18:2683-91
    • (1999) EMBO J. , vol.18 , pp. 2683-2691
    • Li, H.W.1    Lucy, A.P.2    Guo, H.S.3    Li, W.X.4    Ji, L.H.5
  • 63
    • 0035798399 scopus 로고    scopus 로고
    • RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs
    • Lipardi C, Wei Q, Paterson BM. 2001. RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs. Cell 107:297-307
    • (2001) Cell , vol.107 , pp. 297-307
    • Lipardi, C.1    Wei, Q.2    Paterson, B.M.3
  • 64
    • 0035059524 scopus 로고    scopus 로고
    • HC-Pro suppression of transgene silencing eliminates the small RNAs but not transgene methylation or the mobile signal
    • Mallory AC, Ely L, Smith TH, Marathe R, Anandalakshmi R, et al. 2001. HC-Pro suppression of transgene silencing eliminates the small RNAs but not transgene methylation or the mobile signal. Plant Cell 13:571-83
    • (2001) Plant Cell , vol.13 , pp. 571-583
    • Mallory, A.C.1    Ely, L.2    Smith, T.H.3    Marathe, R.4    Anandalakshmi, R.5
  • 65
    • 0035500594 scopus 로고    scopus 로고
    • Stop making nonSense: The C. elegans smg genes
    • Mango SE. 2001. Stop making nonSense: the C. elegans smg genes. Trends Genet. 17:646-53
    • (2001) Trends Genet. , vol.17 , pp. 646-653
    • Mango, S.E.1
  • 66
    • 0033828957 scopus 로고    scopus 로고
    • RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing
    • Marathe R, Anandalakshmi R, Smith TH, Pruss GJ, Vance VB. 2000. RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing. Plant Mol. Biol. 43:295-306
    • (2000) Plant Mol. Biol. , vol.43 , pp. 295-306
    • Marathe, R.1    Anandalakshmi, R.2    Smith, T.H.3    Pruss, G.J.4    Vance, V.B.5
  • 68
    • 0000213492 scopus 로고
    • Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants
    • Matzke MA, Primig M, Trnovsky J, Matzke AJM. 1989. Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J. 8:643-49
    • (1989) EMBO J. , vol.8 , pp. 643-649
    • Matzke, M.A.1    Primig, M.2    Trnovsky, J.3    Matzke, A.J.M.4
  • 70
    • 0031826316 scopus 로고    scopus 로고
    • Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression
    • Montgomery MK, Fire A. 1998. Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression. Trends Genet. 14:255-58
    • (1998) Trends Genet. , vol.14 , pp. 255-258
    • Montgomery, M.K.1    Fire, A.2
  • 71
    • 0032417618 scopus 로고    scopus 로고
    • RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
    • Montgomery MK, Xu S, Fire A. 1998. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 95:15502-7
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15502-15507
    • Montgomery, M.K.1    Xu, S.2    Fire, A.3
  • 72
    • 0036009918 scopus 로고    scopus 로고
    • Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance
    • Morel JB, Godon C, Mourrain P, Beclin C, Boutet S, et al. 2002. Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance. Plant Cell 14:629-39
    • (2002) Plant Cell , vol.14 , pp. 629-639
    • Morel, J.B.1    Godon, C.2    Mourrain, P.3    Beclin, C.4    Boutet, S.5
  • 73
    • 0034658928 scopus 로고    scopus 로고
    • Non-coding RNA's: Lightning strikes twice
    • Moss EG. 2000. Non-coding RNA's: lightning strikes twice. Curr. Biol. 10:R436-39
    • (2000) Curr. Biol. , vol.10
    • Moss, E.G.1
  • 74
    • 0037087780 scopus 로고    scopus 로고
    • miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
    • Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, et al. 2002. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16:720-28
    • (2002) Genes Dev. , vol.16 , pp. 720-728
    • Mourelatos, Z.1    Dostie, J.2    Paushkin, S.3    Sharma, A.4    Charroux, B.5
  • 75
    • 0034716907 scopus 로고    scopus 로고
    • Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance
    • Mourrain P, Beclin C, Elmayan T, Feuerbach F, Godon C, et al. 2000. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance. Cell 101:533-42
    • (2000) Cell , vol.101 , pp. 533-542
    • Mourrain, P.1    Beclin, C.2    Elmayan, T.3    Feuerbach, F.4    Godon, C.5
  • 76
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans
    • Napoli C, Lemieux C, Jorgensen RA. 1990. Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2:279-89
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.A.3
  • 77
    • 0032410928 scopus 로고    scopus 로고
    • Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
    • Ngo H, Tschudi C, Gull K, Ullu E. 1998. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc. Natl. Acad. Sci. USA 95:14687-92
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14687-14692
    • Ngo, H.1    Tschudi, C.2    Gull, K.3    Ullu, E.4
  • 78
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • Nykanen A, Haley B, Zamore PD. 2001. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107:309-21
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 79
  • 80
    • 0036184188 scopus 로고    scopus 로고
    • RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
    • Pal-Bhadra M, Bhadra U, Birchler JA. 2002. RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol. Cell 9:315-27
    • (2002) Mol. Cell , vol.9 , pp. 315-327
    • Pal-Bhadra, M.1    Bhadra, U.2    Birchler, J.A.3
  • 81
    • 0030875953 scopus 로고    scopus 로고
    • Systemic acquired silencing: Transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
    • Palauqui JC, Elmayan T, Pollien JM, Vaucheret H. 1997. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16:4738-45
    • (1997) EMBO J. , vol.16 , pp. 4738-4745
    • Palauqui, J.C.1    Elmayan, T.2    Pollien, J.M.3    Vaucheret, H.4
  • 82
    • 0032483012 scopus 로고    scopus 로고
    • Transgenes are dispensable for the RNA degradation step of cosuppression
    • Palauqui JC, Vaucheret H. 1998. Transgenes are dispensable for the RNA degradation step of cosuppression. Proc. Natl. Acad. Sci. USA 95:9675-80
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9675-9680
    • Palauqui, J.C.1    Vaucheret, H.2
  • 83
    • 0034757613 scopus 로고    scopus 로고
    • Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans
    • Parrish S, Fire A. 2001. Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans. RNA 7:1397-402
    • (2001) RNA , vol.7 , pp. 1397-1402
    • Parrish, S.1    Fire, A.2
  • 84
    • 0033634682 scopus 로고    scopus 로고
    • Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
    • Parrish S, Fleenor J, Xu S, Mello C, Fire A. 2000. Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol. Cell 6:1077-87
    • (2000) Mol. Cell , vol.6 , pp. 1077-1087
    • Parrish, S.1    Fleenor, J.2    Xu, S.3    Mello, C.4    Fire, A.5
  • 85
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, et al. 2000. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408:86-89
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.3    Martindale, M.Q.4    Kuroda, M.I.5
  • 86
    • 0037123606 scopus 로고    scopus 로고
    • RNA silencing: The genome's immune system
    • Plasterk RH. 2002. RNA silencing: the genome's immune system. Science 296:1263-65
    • (2002) Science , vol.296 , pp. 1263-1265
    • Plasterk, R.H.1
  • 87
    • 0031153997 scopus 로고    scopus 로고
    • Plant viral synergism: The potyviral genome encodes a broad-range pathogenicity enhancer that transactivates replication of heterologous viruses
    • Pruss G, Ge X, Shi XM, Carrington JC, Vance VB. 1997. Plant viral synergism: the potyviral genome encodes a broad-range pathogenicity enhancer that transactivates replication of heterologous viruses. Plant Cell 9:859-68
    • (1997) Plant Cell , vol.9 , pp. 859-868
    • Pruss, G.1    Ge, X.2    Shi, X.M.3    Carrington, J.C.4    Vance, V.B.5
  • 88
    • 0031421379 scopus 로고    scopus 로고
    • The frequency and degree of co-suppression by sense chalcone synthase transgenes are dependent on transgene promoter strength and are reduced by premature nonsense codons in the transgene coding sequence
    • Que Q, Wang H-Y, English JJ, Jorgensen RA. 1997. The frequency and degree of co-suppression by sense chalcone synthase transgenes are dependent on transgene promoter strength and are reduced by premature nonsense codons in the transgene coding sequence. Plant Cell 9:1357-68
    • (1997) Plant Cell , vol.9 , pp. 1357-1368
    • Que, Q.1    Wang, H.-Y.2    English, J.J.3    Jorgensen, R.A.4
  • 89
    • 0030992349 scopus 로고    scopus 로고
    • A similarity between viral defense and gene silencing in plants
    • Ratcliff F, Harrison BD, Baulcombe DC. 1997. A similarity between viral defense and gene silencing in plants. Science 276:1558-60
    • (1997) Science , vol.276 , pp. 1558-1560
    • Ratcliff, F.1    Harrison, B.D.2    Baulcombe, D.C.3
  • 90
    • 0032726038 scopus 로고    scopus 로고
    • Gene silencing without DNA. RNA-mediated cross-protection between viruses
    • Ratcliff FG, MacFarlane SA, Baulcombe DC. 1999. Gene silencing without DNA. RNA-mediated cross-protection between viruses. Plant Cell 11:1207-16
    • (1999) Plant Cell , vol.11 , pp. 1207-1216
    • Ratcliff, F.G.1    MacFarlane, S.A.2    Baulcombe, D.C.3
  • 91
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, et al. 2000. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403:901-6
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3    Pasquinelli, A.E.4    Bettinger, J.C.5
  • 92
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano N, Macino G. 1992. Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol. Microbiol. 6:3343-53
    • (1992) Mol. Microbiol. , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 93
    • 3643145804 scopus 로고    scopus 로고
    • Initiation and maintenance of virus-induced gene silencing
    • Ruiz MT, Voinnet O, Baulcombe DC. 1998. Initiation and maintenance of virus-induced gene silencing. Plant Cell 10:937-46
    • (1998) Plant Cell , vol.10 , pp. 937-946
    • Ruiz, M.T.1    Voinnet, O.2    Baulcombe, D.C.3
  • 94
    • 0035955406 scopus 로고    scopus 로고
    • Molecular biology. Glimpses of a tiny RNA world
    • Ruvkun G. 2001. Molecular biology. Glimpses of a tiny RNA world. Science 294:797-99
    • (2001) Science , vol.294 , pp. 797-799
    • Ruvkun, G.1
  • 95
    • 0027323008 scopus 로고
    • RNA-directed RNA polymerase from tomato leaves. I. Purification and physical properties
    • Schiebel W, Haas B, Marinkovic S, Klanner A, Sanger HL. 1993. RNA-directed RNA polymerase from tomato leaves. I. Purification and physical properties. J. Biol. Chem. 268:11851-57
    • (1993) J. Biol. Chem. , vol.268 , pp. 11851-11857
    • Schiebel, W.1    Haas, B.2    Marinkovic, S.3    Klanner, A.4    Sanger, H.L.5
  • 96
    • 0027298691 scopus 로고
    • RNA-directed RNA polymerase from tomato leaves. II. Catalytic in vitro properties
    • Schiebel W, Haas B, Marinkovic S, Klanner A, Sanger HL. 1993. RNA-directed RNA polymerase from tomato leaves. II. Catalytic in vitro properties. J. Biol. Chem. 268:11858-67
    • (1993) J. Biol. Chem. , vol.268 , pp. 11858-11867
    • Schiebel, W.1    Haas, B.2    Marinkovic, S.3    Klanner, A.4    Sanger, H.L.5
  • 97
    • 0036570589 scopus 로고    scopus 로고
    • Why do miRNAs live in the miRNP?
    • Schwarz DS, Zamore PD. 2002. Why do miRNAs live in the miRNP? Genes Dev. 16:1025-31
    • (2002) Genes Dev. , vol.16 , pp. 1025-1031
    • Schwarz, D.S.1    Zamore, P.D.2
  • 98
    • 0035900651 scopus 로고    scopus 로고
    • On the role of RNA amplification in dsRNA-triggered gene silencing
    • Sijen T, Fleenor J, Simmer F, Thijssen KL, Parrish S, et al. 2001. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107:465-76
    • (2001) Cell , vol.107 , pp. 465-476
    • Sijen, T.1    Fleenor, J.2    Simmer, F.3    Thijssen, K.L.4    Parrish, S.5
  • 99
    • 0031468448 scopus 로고    scopus 로고
    • Temporal pattern formation by heterochronic genes
    • Slack F, Ruvkun G. 1997. Temporal pattern formation by heterochronic genes. Annu. Rev. Genet. 31:611-34
    • (1997) Annu. Rev. Genet. , vol.31 , pp. 611-634
    • Slack, F.1    Ruvkun, G.2
  • 100
    • 0034708215 scopus 로고    scopus 로고
    • EGO-1 is related to RNA-directed RNA polymerase and functions in germline development and RNA interference in C. elegans
    • Smardon A, Spoerke JM, Stacey SC, Klein ME, Mackin N, Maine EM. 2000. EGO-1 is related to RNA-directed RNA polymerase and functions in germline development and RNA interference in C. elegans. Curr. Biol. 10:169-78
    • (2000) Curr. Biol. , vol.10 , pp. 169-178
    • Smardon, A.1    Spoerke, J.M.2    Stacey, S.C.3    Klein, M.E.4    Mackin, N.5    Maine, E.M.6
  • 101
    • 0025683324 scopus 로고
    • Expression of a truncated tomato polygalacturonase gene inhibits expression of the endogenous gene in transgenic plants
    • Smith CJ, Watson CF, Bird CR, Ray J, Schuch W, Grierson D. 1990. Expression of a truncated tomato polygalacturonase gene inhibits expression of the endogenous gene in transgenic plants. Mol. Gen. Genet. 224:477-81
    • (1990) Mol. Gen. Genet. , vol.224 , pp. 477-481
    • Smith, C.J.1    Watson, C.F.2    Bird, C.R.3    Ray, J.4    Schuch, W.5    Grierson, D.6
  • 102
    • 0030846433 scopus 로고    scopus 로고
    • Post-transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats
    • Stam M, de Bruin R, Kenter S, van der Hoorn RA, van Blokland R, et al. 1997. Post-transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats. Plant J. 12:63-82
    • (1997) Plant J. , vol.12 , pp. 63-82
    • Stam, M.1    De Bruin, R.2    Kenter, S.3    Van Der Hoorn, R.A.4    Van Blokland, R.5
  • 103
    • 0034002457 scopus 로고    scopus 로고
    • Distinct features of post-transcriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci
    • Stam M, de Bruin R, van Blokland R, van der Hoorn RA, Mol JN, Kooter JM. 2000. Distinct features of post-transcriptional gene silencing by antisense transgenes in single copy and inverted T-DNA repeat loci. Plant J. 21:27-42
    • (2000) Plant J. , vol.21 , pp. 27-42
    • Stam, M.1    De Bruin, R.2    Van Blokland, R.3    Van Der Hoorn, R.A.4    Mol, J.N.5    Kooter, J.M.6
  • 104
    • 0032538391 scopus 로고    scopus 로고
    • RNAi in C. elegans: Soaking in the genome sequence
    • Tabara H, Grishok A, Mello CC. 1998. RNAi in C. elegans: soaking in the genome sequence. Science 282:430-31
    • (1998) Science , vol.282 , pp. 430-431
    • Tabara, H.1    Grishok, A.2    Mello, C.C.3
  • 105
    • 0032717319 scopus 로고    scopus 로고
    • The rde-1 gene, RNA interference, and transposon silencing in C. elegans
    • Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, et al. 1999. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99:123-32
    • (1999) Cell , vol.99 , pp. 123-132
    • Tabara, H.1    Sarkissian, M.2    Kelly, W.G.3    Fleenor, J.4    Grishok, A.5
  • 106
    • 0037169034 scopus 로고    scopus 로고
    • RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs
    • Tijsterman M, Ketting RF, Okihara KL, Sijen T, Plasterk RH. 2002. RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs. Science 295:694-97
    • (2002) Science , vol.295 , pp. 694-697
    • Tijsterman, M.1    Ketting, R.F.2    Okihara, K.L.3    Sijen, T.4    Plasterk, R.H.5
  • 107
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons L, Court DL, Fire A. 2001. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263:103-12
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 108
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L, Fire A. 1998. Specific interference by ingested dsRNA. Nature 395:854
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 110
    • 0035999373 scopus 로고    scopus 로고
    • Spreading of RNA targeting and DNA methylation in RNA silencing requires. Transcription of the target gene and a putative RNA-dependent RNA polymerase
    • Vaistij FE, Jones L, Baulcombe DC. 2002. Spreading of RNA targeting and DNA methylation in RNA silencing requires. Transcription of the target gene and a putative RNA-dependent RNA polymerase. Plant Cell 14:857-67
    • (2002) Plant Cell , vol.14 , pp. 857-867
    • Vaistij, F.E.1    Jones, L.2    Baulcombe, D.C.3
  • 111
    • 0028322448 scopus 로고
    • Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover
    • van Blokland R, van der Geest N, Mol JN, Kooter JM. 1994. Transgene-mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover. Plant J. 6:861-77
    • (1994) Plant J. , vol.6 , pp. 861-877
    • Van Blokland, R.1    Van Der Geest, N.2    Mol, J.N.3    Kooter, J.M.4
  • 112
    • 0025405838 scopus 로고
    • Flavonoid genes in Petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
    • van der Krol AR, Mur LA, Beld M, Mol JN, Stuitje AR. 1990. Flavonoid genes in Petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell 2:291-99
    • (1990) Plant Cell , vol.2 , pp. 291-299
    • Van Der Krol, A.R.1    Mur, L.A.2    Beld, M.3    Mol, J.N.4    Stuitje, A.R.5
  • 113
    • 0035933512 scopus 로고    scopus 로고
    • RNA silencing in plants - Defense and counter-defense
    • Vance V, Vaucheret H. 2001. RNA silencing in plants - defense and counter-defense. Science 292:2277-80
    • (2001) Science , vol.292 , pp. 2277-2280
    • Vance, V.1    Vaucheret, H.2
  • 115
    • 0034789243 scopus 로고    scopus 로고
    • Post-transcriptional gene silencing in plants
    • Vaucheret H, Beclin C, Fagard M. 2001. Post-transcriptional gene silencing in plants. J. Cell Sci. 114:3083-91
    • (2001) J. Cell Sci. , vol.114 , pp. 3083-3091
    • Vaucheret, H.1    Beclin, C.2    Fagard, M.3
  • 116
    • 0035054777 scopus 로고    scopus 로고
    • Transcriptional gene silencing in plants: Targets, inducers and regulators
    • Vaucheret H, Fagard M. 2001. Transcriptional gene silencing in plants: targets, inducers and regulators. Trends Genet. 17:29-35
    • (2001) Trends Genet. , vol.17 , pp. 29-35
    • Vaucheret, H.1    Fagard, M.2
  • 117
    • 0031412527 scopus 로고    scopus 로고
    • A transcriptionally active state is required for post-transcriptional silencing (co-suppression) of nitrate reductase host genes and transgenes
    • Vaucheret H, Nussaume L, Palauqui J-C, Quillere I, Elmayan T. 1997. A transcriptionally active state is required for post-transcriptional silencing (co-suppression) of nitrate reductase host genes and transgenes. Plant Cell 9:1495-504
    • (1997) Plant Cell , vol.9 , pp. 1495-1504
    • Vaucheret, H.1    Nussaume, L.2    Palauqui, J.-C.3    Quillere, I.4    Elmayan, T.5
  • 118
    • 0035425379 scopus 로고    scopus 로고
    • RNA silencing as a plant immune system against viruses
    • Voinnet O. 2001. RNA silencing as a plant immune system against viruses. Trends Genet. 17:449-59
    • (2001) Trends Genet. , vol.17 , pp. 449-459
    • Voinnet, O.1
  • 119
    • 0030798444 scopus 로고    scopus 로고
    • Systemic signalling in gene silencing
    • Voinnet O, Baulcombe DC. 1997. Systemic signalling in gene silencing. Nature 389:553
    • (1997) Nature , vol.389 , pp. 553
    • Voinnet, O.1    Baulcombe, D.C.2
  • 120
    • 0034730318 scopus 로고    scopus 로고
    • A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana
    • Voinnet O, Lederer C, Baulcombe DC. 2000. A viral movement protein prevents spread of the gene silencing signal in Nicotiana benthamiana. Cell 103:157-67
    • (2000) Cell , vol.103 , pp. 157-167
    • Voinnet, O.1    Lederer, C.2    Baulcombe, D.C.3
  • 121
    • 0033598840 scopus 로고    scopus 로고
    • Suppression of gene silencing: A general strategy used by diverse DNA and RNA viruses of plants
    • Voinnet O, Pinto YM, Baulcombe DC. 1999. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc. Natl. Acad. Sci. USA 96:14147-52
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14147-14152
    • Voinnet, O.1    Pinto, Y.M.2    Baulcombe, D.C.3
  • 122
    • 0032538348 scopus 로고    scopus 로고
    • Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA
    • Voinnet O, Vain P, Angell S, Baulcombe DC. 1998. Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA. Cell 95:177-87
    • (1998) Cell , vol.95 , pp. 177-187
    • Voinnet, O.1    Vain, P.2    Angell, S.3    Baulcombe, D.C.4
  • 123
    • 0032506226 scopus 로고    scopus 로고
    • Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
    • Waterhouse PM, Graham MW, Wang MB. 1998. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc. Natl. Acad. Sci. USA 95:13959-64
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13959-13964
    • Waterhouse, P.M.1    Graham, M.W.2    Wang, M.B.3
  • 124
    • 0037076320 scopus 로고    scopus 로고
    • ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
    • Williams RW, Rubin GM. 2002. ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc. Natl. Acad. Sci. USA 99:6889-94
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6889-6894
    • Williams, R.W.1    Rubin, G.M.2
  • 125
    • 0037192490 scopus 로고    scopus 로고
    • Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1
    • Winston WM, Molodowitch C, Hunter CP. 2002. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 295:2456-59
    • (2002) Science , vol.295 , pp. 2456-2459
    • Winston, W.M.1    Molodowitch, C.2    Hunter, C.P.3
  • 126
    • 0034634360 scopus 로고    scopus 로고
    • Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase
    • Wu-Scharf D, Jeong B, Zhang C, Cerutti H. 2000. Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase. Science 290:1159-62
    • (2000) Science , vol.290 , pp. 1159-1162
    • Wu-Scharf, D.1    Jeong, B.2    Zhang, C.3    Cerutti, H.4
  • 127
    • 0037123601 scopus 로고    scopus 로고
    • Ancient pathways programmed by small RNAs
    • Zamore PD. 2002. Ancient pathways programmed by small RNAs. Science 296:1265-69
    • (2002) Science , vol.296 , pp. 1265-1269
    • Zamore, P.D.1
  • 128
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore PD, Tuschl T, Sharp PA, Barrel DP. 2000. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101:25-33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Barrel, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.