-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A. et al. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
-
2
-
-
0035281741
-
RNA interference - 2001
-
Sharp, P.A. (2001) RNA interference - 2001. Genes Dev. 15, 485-490
-
(2001)
Genes Dev.
, vol.15
, pp. 485-490
-
-
Sharp, P.A.1
-
3
-
-
0034877670
-
RNA interference: Listening to the sound of silence
-
Zamore, P.D. (2001) RNA interference: listening to the sound of silence. Nat. Struct. Biol. 8, 746-750
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 746-750
-
-
Zamore, P.D.1
-
4
-
-
0037062951
-
RNA interference
-
Hannon, G.J. (2002) RNA interference. Nature 418, 244-251
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
5
-
-
0036953376
-
The genetics of RNA silencing
-
Tijsterman, M. et al. (2002) The genetics of RNA silencing. Annu. Rev. Genet. 36, 489-519
-
(2002)
Annu. Rev. Genet.
, vol.36
, pp. 489-519
-
-
Tijsterman, M.1
-
6
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S.M. et al. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
-
7
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus, M.T. et al. (2002) Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3, 737-747
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
-
8
-
-
0032578911
-
Specific interference by ingested dsRNA
-
Timmons, L. et al. (1998) Specific interference by ingested dsRNA. Nature 395, 854
-
(1998)
Nature
, vol.395
, pp. 854
-
-
Timmons, L.1
-
9
-
-
0001359591
-
Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
-
Napoli, C. et al. (1990) Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2, 279-289
-
(1990)
Plant Cell
, vol.2
, pp. 279-289
-
-
Napoli, C.1
-
10
-
-
0025134418
-
Altered gene expression in plants due to trans interactions between homologous genes
-
Jorgensen, R. (1990) Altered gene expression in plants due to trans interactions between homologous genes. Trends Biotechnol. 8, 340-344
-
(1990)
Trends Biotechnol.
, vol.8
, pp. 340-344
-
-
Jorgensen, R.1
-
11
-
-
0030220502
-
Chalcone synthase cosuppression phenotypes in petunia flowers: Comparison of sense vs antisense constructs and single-copy vs complex T-DNA sequences
-
Jorgensen, R.A. et al. (1996) Chalcone synthase cosuppression phenotypes in petunia flowers: comparison of sense vs antisense constructs and single-copy vs complex T-DNA sequences. Plant Mol. Biol. 31, 957-973
-
(1996)
Plant Mol. Biol.
, vol.31
, pp. 957-973
-
-
Jorgensen, R.A.1
-
12
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen, T. et al. (2001) On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 107, 465-476
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
-
13
-
-
0032304201
-
Isolation of an RNA-directed RNA polymerase-specific cDNA clone from tomato
-
Schiebel, W. et al. (1998) Isolation of an RNA-directed RNA polymerase-specific cDNA clone from tomato. Plant Cell 10, 2087-2101
-
(1998)
Plant Cell
, vol.10
, pp. 2087-2101
-
-
Schiebel, W.1
-
14
-
-
0037443089
-
siRNAs can function as miRNAs
-
Doench, J.G. et al. (2003) siRNAs can function as miRNAs. Genes Dev. 17, 438-442
-
(2003)
Genes Dev.
, vol.17
, pp. 438-442
-
-
Doench, J.G.1
-
15
-
-
0028031830
-
RNA-directed de novo methylation of genomic sequences in plants
-
Wassenegger, M. et al. (1994) RNA-directed de novo methylation of genomic sequences in plants. Cell 76, 567-576
-
(1994)
Cell
, vol.76
, pp. 567-576
-
-
Wassenegger, M.1
-
16
-
-
0036184188
-
RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
-
Pal-Bhadra, M. et al. (2002) RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol. Cell 9, 315-327
-
(2002)
Mol. Cell
, vol.9
, pp. 315-327
-
-
Pal-Bhadra, M.1
-
17
-
-
0033215511
-
Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences
-
Pal-Bhadra, M. et al. (1999) Cosuppression of nonhomologous transgenes in Drosophila involves mutually related endogenous sequences. Cell 99, 35-46
-
(1999)
Cell
, vol.99
, pp. 35-46
-
-
Pal-Bhadra, M.1
-
18
-
-
0036008547
-
Control of developmental timing by small temporal RNAs: A paradigm for RNA-mediated regulation of gene expression
-
Banerjee, D. et al. (2002) Control of developmental timing by small temporal RNAs: a paradigm for RNA-mediated regulation of gene expression. Bioessays 24, 119-129
-
(2002)
Bioessays
, vol.24
, pp. 119-129
-
-
Banerjee, D.1
-
19
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner, G. et al. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science 297, 2056-2060
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
-
20
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
Hamilton, A.J. et al. (1999) A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286, 950-952
-
(1999)
Science
, vol.286
, pp. 950-952
-
-
Hamilton, A.J.1
-
21
-
-
0037009520
-
Two classes of short interfering RNA in RNA silencing
-
Hamilton, A. et al. (2002) Two classes of short interfering RNA in RNA silencing. EMBO J. 21, 4671-4679
-
(2002)
EMBO J.
, vol.21
, pp. 4671-4679
-
-
Hamilton, A.1
-
22
-
-
0037474126
-
ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation
-
Zilberman, D. et al. (2003) ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science 299, 716-719
-
(2003)
Science
, vol.299
, pp. 716-719
-
-
Zilberman, D.1
-
23
-
-
0037224921
-
A biochemical framework for RNA silencing in plants
-
Tang, G. et al. (2003) A biochemical framework for RNA silencing in plants. Genes Dev. 17, 49-63
-
(2003)
Genes Dev.
, vol.17
, pp. 49-63
-
-
Tang, G.1
-
24
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore, P.D. et al. (2000) RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101, 25-33
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
-
25
-
-
0033634682
-
Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
-
Parrish, S. et al. (2000) Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference. Mol. Cell 6, 1077-1087
-
(2000)
Mol. Cell
, vol.6
, pp. 1077-1087
-
-
Parrish, S.1
-
26
-
-
0034609759
-
Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
-
Yang, D. et al. (2000) Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos. Curr. Biol. 10, 1191-1200
-
(2000)
Curr. Biol.
, vol.10
, pp. 1191-1200
-
-
Yang, D.1
-
27
-
-
0034673638
-
An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells
-
Hammond, S.M. et al. (2000) An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells. Nature 404, 293-296
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
-
28
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir, S.M. et al. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20, 6877-6888
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
-
29
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E. et al. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
-
30
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting, R.F. et al. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-2659
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
-
31
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight, S.W. et al. (2001) A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293, 2269-2271
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
-
32
-
-
0037422606
-
RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast
-
Hall, I.M. et al. (2003) RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc. Natl. Acad. Sci. U. S. A. 100, 193-198
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 193-198
-
-
Hall, I.M.1
-
33
-
-
0037183856
-
Establishment and maintenance of a heterochromatin domain
-
Hall, I.M. et al. (2002) Establishment and maintenance of a heterochromatin domain. Science 297, 2232-2237
-
(2002)
Science
, vol.297
, pp. 2232-2237
-
-
Hall, I.M.1
-
34
-
-
0037072661
-
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
-
Volpe, T.A. et al. (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297, 1833-1837
-
(2002)
Science
, vol.297
, pp. 1833-1837
-
-
Volpe, T.A.1
-
35
-
-
0032443021
-
Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
-
Kennerdell, J.R. et al. (1998) Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95, 1017-1026
-
(1998)
Cell
, vol.95
, pp. 1017-1026
-
-
Kennerdell, J.R.1
-
36
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl, T. et al. (1999) Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13, 3191-3197
-
(1999)
Genes Dev.
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
-
37
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
Nykanen, A. et al. (2001) ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107, 309-321
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
-
38
-
-
0032717319
-
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
-
Tabara, H. et al. (1999) The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99, 123-132
-
(1999)
Cell
, vol.99
, pp. 123-132
-
-
Tabara, H.1
-
39
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond, S.M. et al. (2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293, 1146-1150
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
-
40
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez, J. et al. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
-
41
-
-
0026381380
-
Interferon-induced and double-stranded RNA-activated enzymes: A specific protein kinase and 2′,5′-oligoadenylate synthetases
-
Hovanessian, A.G. (1991) Interferon-induced and double-stranded RNA-activated enzymes: a specific protein kinase and 2′,5′ -oligoadenylate synthetases. J. Interferon Res. 11, 199-205
-
(1991)
J. Interferon Res.
, vol.11
, pp. 199-205
-
-
Hovanessian, A.G.1
-
42
-
-
0027931663
-
Fascination with 2-5A-dependent RNase: A unique enzyme that functions in interferon action
-
Silverman, R.H. (1994) Fascination with 2-5A-dependent RNase: a unique enzyme that functions in interferon action. J. Interferon Res. 14, 101-104
-
(1994)
J. Interferon Res.
, vol.14
, pp. 101-104
-
-
Silverman, R.H.1
-
43
-
-
0028815704
-
Regulation of the interferon-induced PKR: Can viruses cope?
-
Katze, M.G. (1995) Regulation of the interferon-induced PKR: can viruses cope? Trends Microbiol. 3, 75-78
-
(1995)
Trends Microbiol.
, vol.3
, pp. 75-78
-
-
Katze, M.G.1
-
44
-
-
0031290258
-
Genetic analysis of interferon and other mammalian signaling pathways
-
Stark, G.R. (1997) Genetic analysis of interferon and other mammalian signaling pathways. Harvey Lect. 93, 1-16
-
(1997)
Harvey Lect.
, vol.93
, pp. 1-16
-
-
Stark, G.R.1
-
45
-
-
0034084338
-
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
-
Gil, J. et al. (2000) Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis 5, 107-114
-
(2000)
Apoptosis
, vol.5
, pp. 107-114
-
-
Gil, J.1
-
46
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir, S.M. et al. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15, 188-200
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
-
47
-
-
0037123630
-
Induction and suppression of RNA silencing by an animal virus
-
Li, H. et al. (2002) Induction and suppression of RNA silencing by an animal virus. Science 296, 1319-1321
-
(2002)
Science
, vol.296
, pp. 1319-1321
-
-
Li, H.1
-
48
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P.J. et al. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
-
49
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen, N.J. et al. (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. U. S. A. 98, 9742-9747
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
-
50
-
-
0037111232
-
Small interfering RNA-mediated gene silencing in T lymphocytes
-
McManus, M.T. et al. (2002) Small interfering RNA-mediated gene silencing in T lymphocytes. J. Immunol. 169, 5754-5760
-
(2002)
J. Immunol.
, vol.169
, pp. 5754-5760
-
-
McManus, M.T.1
-
51
-
-
0036273940
-
Gene silencing using micro-RNA designed hairpins
-
McManus, M.T. et al. (2002) Gene silencing using micro-RNA designed hairpins. RNA 8, 842-850
-
(2002)
RNA
, vol.8
, pp. 842-850
-
-
McManus, M.T.1
-
52
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul, C.P. et al. (2002) Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20, 505-508
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
-
53
-
-
0036245628
-
U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
-
Miyagishi, M. et al. (2002) U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20, 497-500
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 497-500
-
-
Miyagishi, M.1
-
54
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui, G. et al. (2002) A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 99, 5515-5520
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
-
55
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey, A.P. et al. (2002) RNA interference in adult mice. Nature 418, 38-39
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
-
56
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis, D.L. et al. (2002) Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32, 107-108
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
-
57
-
-
17944363138
-
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding
-
Garrus, J.E. et al. (2001) Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell 107, 55-65
-
(2001)
Cell
, vol.107
, pp. 55-65
-
-
Garrus, J.E.1
-
58
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp, T. et al. (2002) Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2, 243-247
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.1
-
59
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda, M. et al. (2002) Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene 21, 5716-5724
-
(2002)
Oncogene
, vol.21
, pp. 5716-5724
-
-
Wilda, M.1
-
60
-
-
0037026601
-
Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
-
Jiang, M. et al. (2002) Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference. Oncogene 21, 6041-6048
-
(2002)
Oncogene
, vol.21
, pp. 6041-6048
-
-
Jiang, M.1
-
61
-
-
0036735367
-
An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis
-
Bhoumik, A. et al. (2002) An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis. J. Clin. Invest. 110, 643-650
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 643-650
-
-
Bhoumik, A.1
-
62
-
-
0037329372
-
RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines
-
Cioca, D.P. et al. (2003) RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer Gene Ther. 10, 125-133
-
(2003)
Cancer Gene Ther.
, vol.10
, pp. 125-133
-
-
Cioca, D.P.1
-
63
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song, E. et al. (2003) RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9, 347-351
-
(2003)
Nat. Med.
, vol.9
, pp. 347-351
-
-
Song, E.1
-
64
-
-
0038610713
-
Caspase 8 siRNA prevents acute liver failure in mice
-
Zender, L. et al. (2003) Caspase 8 siRNA prevents acute liver failure in mice. Proc. Natl. Acad. Sci. U. S. A. 100, 7797-7802
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7797-7802
-
-
Zender, L.1
-
65
-
-
0036787671
-
siRNA-mediated gene silencing in vitro and in vivo
-
Xia, H. et al. (2002) siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20, 1006-1010
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1006-1010
-
-
Xia, H.1
-
66
-
-
19044381013
-
Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
-
Bitko, V. et al. (2001) Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses. BMC Microbiol. 1, 34
-
(2001)
BMC Microbiol.
, vol.1
, pp. 34
-
-
Bitko, V.1
-
67
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee, N.S. et al. (2002) Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20, 500-505
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
-
68
-
-
0036066508
-
siRNA-directed inhibition of HIV-1 infection
-
Novina, C.D. et al. (2002) siRNA-directed inhibition of HIV-1 infection. Nat. Med. 8, 681-686
-
(2002)
Nat. Med.
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
-
69
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque, J.M. et al. (2002) Modulation of HIV-1 replication by RNA interference. Nature 418, 435-438
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.M.1
-
70
-
-
0037031148
-
Inhibition of retroviral pathogenesis by RNA interference
-
Hu, W. et al. (2002) Inhibition of retroviral pathogenesis by RNA interference. Curr. Biol. 12, 1301-1311
-
(2002)
Curr. Biol.
, vol.12
, pp. 1301-1311
-
-
Hu, W.1
-
71
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn, G.A. et al. (2002) Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol. 76, 9225-9231
-
(2002)
J. Virol.
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
-
72
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici, J. et al. (2002) Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J. Immunol. 169, 5196-5201
-
(2002)
J. Immunol.
, vol.169
, pp. 5196-5201
-
-
Capodici, J.1
-
73
-
-
0037173613
-
Short interfering RNA confers intracellular antiviral immunity in human cells
-
Gitlin, L. et al. (2002) Short interfering RNA confers intracellular antiviral immunity in human cells. Nature 418, 430-434
-
(2002)
Nature
, vol.418
, pp. 430-434
-
-
Gitlin, L.1
-
74
-
-
10744230911
-
Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
-
Yokota, T. et al. (2003) Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO Rep. 4, 602-608
-
(2003)
EMBO Rep.
, vol.4
, pp. 602-608
-
-
Yokota, T.1
-
75
-
-
0038731180
-
Short interfering RNA-directed inhibition of hepatitis B virus replication
-
Hamasaki, K. et al. (2003) Short interfering RNA-directed inhibition of hepatitis B virus replication. FEBS Lett. 543, 51-54
-
(2003)
FEBS Lett.
, vol.543
, pp. 51-54
-
-
Hamasaki, K.1
-
76
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey, A.P. et al. (2003) Inhibition of hepatitis B virus in mice by RNA interference. Nat. Biotechnol. 21, 639-644
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
-
77
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Ge, Q. et al. (2003) RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc. Natl. Acad. Sci. U. S. A. 100, 2718-2723
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2718-2723
-
-
Ge, Q.1
-
78
-
-
0037663944
-
Sustained small interfering RNA-mediated human immunodeficiency type 1 inhibition in primary macrophages
-
Song, E. et al. (2003) Sustained small interfering RNA-mediated human immunodeficiency type 1 inhibition in primary macrophages. J. Virol. 77, 7174-7181
-
(2003)
J. Virol.
, vol.77
, pp. 7174-7181
-
-
Song, E.1
-
79
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin, X.F. et al. (2003) Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. U. S. A. 100, 183-188
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
-
80
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson, A.L. et al. (2003) Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21, 635-637
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
-
81
-
-
0037197914
-
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
-
Yu, J.Y. et al. (2002) RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 99, 6047-6052
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
-
82
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng, Y. et al. (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9, 1327-1333
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
-
83
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson, D.A. et al. (2003) A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33, 401-406
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
-
84
-
-
0344375083
-
Lentivirus-delivered stable gene silencing by RNAi in primary cells
-
Stewart, S.A. et al. (2003) Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9, 493-501
-
(2003)
RNA
, vol.9
, pp. 493-501
-
-
Stewart, S.A.1
-
85
-
-
0038303229
-
Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin
-
Wang, J. et al. (2003) Stable and controllable RNA interference: investigating the physiological function of glutathionylated actin. Proc. Natl. Acad. Sci. U. S. A. 100, 5103-5106
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 5103-5106
-
-
Wang, J.1
-
86
-
-
0037108818
-
Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
-
Yang, P.L. et al. (2002) Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proc. Natl. Acad. Sci. U. S. A. 99, 13825-13830
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 13825-13830
-
-
Yang, P.L.1
-
87
-
-
0033692912
-
Nuclease-resistant synthetic ribozymes: Developing a new class of therapeutics
-
Usman, N. et al. (2000) Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics. J. Clin. Invest. 106, 1197-1202
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1197-1202
-
-
Usman, N.1
-
88
-
-
0037440005
-
Tolerance for mutations and chemical modifications in a siRNA
-
Amarzguioui, M. et al. (2003) Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31, 589-595
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 589-595
-
-
Amarzguioui, M.1
-
89
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
Czauderna, F. et al. (2003) Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 31, 2705-2716
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
-
90
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth, J. et al. (2003) Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev. 13, 83-105
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 83-105
-
-
Harborth, J.1
-
91
-
-
0037063996
-
Nuclear targeting of macromolecular polyanions by an HIV-tat derived peptide. Role for cell-surface proteoglycans
-
Sandgren, S. et al. (2002) Nuclear targeting of macromolecular polyanions by an HIV-tat derived peptide. Role for cell-surface proteoglycans. J. Biol. Chem. 277, 38877-38883
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38877-38883
-
-
Sandgren, S.1
-
92
-
-
0037592877
-
Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells
-
Simeoni, F. et al. (2003) Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells. Nucleic Acids Res. 31, 2717-2724
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2717-2724
-
-
Simeoni, F.1
-
93
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
Bertrand, J.R. et al. (2002) Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem. Biophys. Res. Commun. 296, 1000-1004
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1000-1004
-
-
Bertrand, J.R.1
-
94
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen, D.R. et al. (2003) Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327, 761-766
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
|