Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Critical Reviews in Toxicology

Volumn 47, Issue 1, 2017, Pages 1-58

  Kuempel, Eileen D ^a   Jaurand, Marie Claude ^b,c,d,e   Møller, Peter ^f   Morimoto, Yasuo ^g   Kobayashi, Norihiro ^h   Pinkerton, Kent E ⁱ   Sargent, Linda M ^a   Vermeulen, Roel C H ^j   Fubini, Bice ^k   Kane, Agnes B ^l  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITÉ PARIS DIDEROT   (France)

^e UNIVERSITÉ PARIS 13   (France)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

^g UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^h NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UTRECHT UNIVERSITY   (Netherlands)

^k UNIVERSITY OF TURIN   (Italy)

^l BROWN UNIVERSITY   (United States)

more..

Author keywords

Cancer mechanisms; carbon nanofibers; carbon nanotubes; cell proliferation; fibrosis; genotoxicity; inflammation; lung cancer; mesothelioma; particle retention; pulmonary; translocation

Indexed keywords

ASBESTOS; CARBON NANOFIBER; CARBON NANOTUBE; DNA; MULTI WALLED NANOTUBE; RADICAL; SINGLE WALLED NANOTUBE; NANOFIBER;

AIRBORNE PARTICLE; ANALYTICAL PARAMETERS; ASBESTOSIS; ATMOSPHERIC DEPOSITION; BODY FLUID; CARCINOGENESIS; CARCINOGENICITY; CELL CULTURE; CELL FREE SYSTEM; CELL INTERACTION; CELL PROLIFERATION; CELL TRANSFORMATION; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CHROMOSOME NUMBER; CHROMOSOME STRUCTURE; CLEARANCE; COMPARATIVE STUDY; DEGRADATION; DNA DAMAGE; DOSIMETRY; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; GENE EXPRESSION; GENE MUTATION; GENOTOXICITY; GENOTOXICITY ASSAY; HUMAN; HYPERPLASIA; IN VITRO STUDY; IN VIVO STUDY; INHALATION; INTRACELLULAR SIGNALING; LUNG; LUNG CANCER; LUNG EPITHELIUM; LUNG FIBROSIS; LUNG GRANULOMA; MESOTHELIUM CELL; MICRONUCLEUS; NANOTOXICOLOGY; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PHYSICAL CHEMISTRY; PLEURA; PLEURA CAVITY; PLEURA MESOTHELIOMA; PLEURAL FIBROSIS; PNEUMONIA; RESPIRATORY SYSTEM; RETENTION KINETICS; REVIEW; RODENT; SOLUBILITY; SURFACE PROPERTY; ANIMAL; CARCINOGEN TESTING;

ANIMALS; CARCINOGENICITY TESTS; HUMANS; NANOFIBERS; NANOTUBES, CARBON;

EID: 85012117657     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.1080/10408444.2016.1206061     Document Type: Review

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